Peroxisome proliferator-activated receptor (PPAR)gamma is expressed by human spermatozoa: its potential role on the sperm physiology.

abstract：:Regulation of lipid synthesis from acetate in human diploid fibroblast cultures has been studied at various passage levels and at different stages of cell growth. When cultures were transferred to lipid free medium, a stimulation of [14C]acetate incorporation into lipid occurred within three to six hours after removal...

journal_title：Journal of cellular physiology

authors： Howard BV,Howard WJ,Kefalides NA

更新日期：1976-10-01 00:00:00

abstract：:Cardiac fibroblast (CF) differentiation to myofibroblasts expressing α-smooth muscle actin (α-SMA) plays a key role in cardiac fibrosis. Therefore, a study of the mechanism regulating α-SMA expression is a means to understanding the mechanism of fibroblast differentiation and cardiac fibrosis. Previous studies have sh...

journal_title：Journal of cellular physiology

authors： He Y,Ling S,Sun Y,Sheng Z,Chen Z,Pan X,Ma G

更新日期：2019-05-01 00:00:00

abstract：:Vero (African green monkey kidney) cells grown in tissue culture monolayer were sensitive to Clostridium perfringens enterotoxin. Within 30 minutes of exposure to the enterotoxin gross morphological damage was observed and within 40 minutes approximately 75% of the cells had detached. Nearly half of the cells were non...

journal_title：Journal of cellular physiology

authors： McClane BA,McDonel JL

更新日期：1979-05-01 00:00:00

abstract：:Apoptosis constitutes a response of organisms to various physiological or pathological stimuli, and to different stresses. The ability of thermotolerance induced at a mild temperature of 40 degrees C to protect against activation of the apoptotic cascade by heat shock was investigated. When Chinese hamster ovary and h...

journal_title：Journal of cellular physiology

authors： Bettaieb A,Averill-Bates DA

更新日期：2005-10-01 00:00:00

abstract：:Epithelial cells are important components of the thymus microenvironment and are involved in thymocyte differentiation. The production and secretion of sulfated glycosaminoglycans by these cells grown in culture were investigated using labeling with radioactive 35S-Na2SO4 and 3H-glucosamine. The major glycosaminoglyca...

journal_title：Journal of cellular physiology

authors： Werneck CC,Oliveira-Dos-Santos AJ,Silva LC,Villa-Verde DM,Savino W,Mourão PA

更新日期：1999-01-01 00:00:00

abstract：:Induction of vascular smooth muscle (VSM) alpha-actin mRNA expression during cytodifferentiation of mouse BC3H1 myogenic cells coincides with the accumulation of cell surface- and extracellular matrix-associated sulfated proteoglycans. Inhibition of proteoglycan biosynthesis in myogenic cells using an artificial beta-...

journal_title：Journal of cellular physiology

authors： Lee SH,Yan H,Reeser JC,Dillman JM,Strauch AR

更新日期：1995-07-01 00:00:00

abstract：:B cell activating factor from the TNF family (BAFF) stimulates B-cell proliferation and survival, but excessive BAFF promotes the development of aggressive B cells leading to malignant and autoimmune diseases. Recently, we have reported that rapamycin, a macrocyclic lactone, attenuates human soluble BAFF (hsBAFF)-stim...

journal_title：Journal of cellular physiology

authors： Zeng Q,Qin S,Zhang H,Liu B,Qin J,Wang X,Zhang R,Liu C,Dong X,Zhang S,Huang S,Chen L

更新日期：2018-01-01 00:00:00

abstract：:Fibroblast growth factors (FGFs) are soluble ligands important for embryonic patterning, limb and brain development, and stem cell proliferation. They activate specific receptors (FGFR) to elicit changes in gene expression and cellular responses such as proliferation, differentiation, and survival, but the extent to w...

journal_title：Journal of cellular physiology

authors： Garcia-Maya M,Anderson AA,Kendal CE,Kenny AV,Edwards-Ingram LC,Holladay A,Saffell JL

更新日期：2006-02-01 00:00:00

abstract：:Adiponectin, one of the adipose-derived hormone with metabolic activity, has been reported to conversely affect angiogenesis of endothelial cells in vitro. The previous study in animal models has demonstrated that adiponectin has a protective role in retinal vascular injury following pathological stimuli. However, cli...

journal_title：Journal of cellular physiology

authors： Li R,Du J,Yao Y,Yao G,Wang X

更新日期：2019-11-01 00:00:00

abstract：:TRB3 (a mammalian homolog of Drosophila) is emerging as an important player in the regulation of insulin signaling. TRB3 can directly bind to Ser/Thr protein kinase Akt, the major downstream kinase of insulin signaling. Conversely, physical exercise has been linked to improved glucose homeostasis and enhanced insulin ...

journal_title：Journal of cellular physiology

authors： Lima AF,Ropelle ER,Pauli JR,Cintra DE,Frederico MJ,Pinho RA,Velloso LA,De Souza CT

更新日期：2009-10-01 00:00:00

abstract：:UDPgalactose inhibits the growth of mouse leukemic L1210 cells. In calf serum supplemented Dulbecco's medium (CS-DMEM), 1.2 mM UDPgalactose (UDPgal) inhibited cell growth by 50% (IC50), and 5 mM UDPgalactose inhibited cell growth by 92%. Other nucleotide sugars as well as galactose, glucose, and galactose-1-phosphate ...

journal_title：Journal of cellular physiology

authors： Klohs WD,Wilson JR,Weiser MM,Frankfurt O,Bernacki RJ

更新日期：1984-04-01 00:00:00

abstract：:As a strategy to identify gene expression changes affected by human polynucleotide phosphorylase (hPNPase(old-35)), we performed gene expression analysis of HeLa cells in which hPNPase(old-35) was overexpressed. The observed changes were then compared to those of HO-1 melanoma cells in which hPNPase(old-35) was stably...

journal_title：Journal of cellular physiology

authors： Sokhi UK,Bacolod MD,Emdad L,Das SK,Dumur CI,Miles MF,Sarkar D,Fisher PB

更新日期：2014-12-01 00:00:00

abstract：:Osteosarcoma is the most common bone tumor in children and young adults. Although the microRNAs (miRNA) expression analyses of osteosarcoma have been performed previously, the construction of miRNA-messenger RNA (mRNA) networks for osteosarcoma is needed. This study aimed to identify osteosarcoma-related miRNAs throug...

journal_title：Journal of cellular physiology

authors： Ma G,Zhang C,Luo W,Zhao JL,Wang X,Qian Y

更新日期：2019-08-01 00:00:00

abstract：:We have previously identified two stimulatory activities affecting blood cell maturation in PHA-stimulated human lymphocytes conditioned medium (PHA-LyCM). One was granulocyte-macrophage colony stimulatory activity (GM-CSA), and the other was T lymphocyte growth stimulatory activity (TL-GSA) in suspension culture. In ...

journal_title：Journal of cellular physiology

authors： Wu AM

更新日期：1979-11-01 00:00:00

abstract：:The epithelium-specific ETS (ESE)-1 transcription factor is induced in chondrocytes by interleukin-1beta (IL-1beta). We reported previously that early activation of EGR-1 by IL-1beta results in suppression of the proximal COL2A1 promoter activity by displacement of Sp1 from GC boxes. Here we report that ESE-1 is a pot...

journal_title：Journal of cellular physiology

authors： Peng H,Tan L,Osaki M,Zhan Y,Ijiri K,Tsuchimochi K,Otero M,Wang H,Choy BK,Grall FT,Gu X,Libermann TA,Oettgen P,Goldring MB

更新日期：2008-05-01 00:00:00

abstract：:Deep vein thrombosis associated with advanced cancer is known as Trousseau's syndrome. We hypothesized that thrombin, an activator of protease-activated receptor (PAR)-1 and PAR-4 contributes to tumor metastasis. In this study, we demonstrated that thrombin and the PAR-1 activating peptide (AP) SFLLRN, but not the PAR...

journal_title：Journal of cellular physiology

authors： Chang LH,Chen CH,Huang DY,Pai HC,Pan SL,Teng CM

更新日期：2011-04-01 00:00:00

abstract：:The present study was to investigate the effects and action mechanisms of digoxin and ouabain on steroidogenesis in human adrenocortical NCI-H295 cells. Administration of digoxin or ouabain for 24 h decreased the basal and angiotensin II (Ang II)-stimulated release of aldosterone by NCI-H295 cells. The conversions of ...

journal_title：Journal of cellular physiology

authors： Kau MM,Kan SF,Wang JR,Wang PS

更新日期：2005-12-01 00:00:00

abstract：:Drug discovery is an onerous, extremely expensive, and time-consuming process. Instead, drug repurposing is an attractive strategy for exploiting novel indications for a drug beyond its original use. The untapped potential of drug repurposing compensates the barriers associated with the drug discovery pipeline. Psoria...

journal_title：Journal of cellular physiology

authors： Thatikonda S,Pooladanda V,Godugu C

更新日期：2020-06-01 00:00:00

abstract：:The serum-free medium conditioned by the human colon cancer cell line HT-29 contains insulin-like growth factors (IGF) that are entirely complexed to binding proteins (IGF-BP). Gel filtration in acid conditions of the cell-conditioned medium permits separation of IGF-BP from two molecular forms of IGF of 15,000 and 7,...

journal_title：Journal of cellular physiology

authors： Culouscou JM,Remacle-Bonnet M,Garrouste F,Fantini J,Marvaldi J,Pommier G

更新日期：1990-06-01 00:00:00

abstract：:It has been reported by us and other groups that the expression of small GTP binding protein RhoB can be induced by genotoxic stressors and glucocorticoid (GC), a stress hormone that plays a key role in stress response. Until now stress-induced genes that confer cytoprotection under stressed conditions are largely unk...

journal_title：Journal of cellular physiology

authors： Li YD,Liu YP,Cao DM,Yan YM,Hou YN,Zhao JY,Yang R,Xia ZF,Lu J

更新日期：2011-03-01 00:00:00

abstract：:The in vitro culture of porcine bone marrow-derived mesenchymal stem cells (MSCs) was used for the investigation of adult stem cell biology. Isolated porcine MSCs possessed the ability to proliferate extensively in an antioxidants-rich medium containing 5% fetal bovine serum (FBS). Greater than 40 serial MSC passages ...

journal_title：Journal of cellular physiology

authors： Vacanti V,Kong E,Suzuki G,Sato K,Canty JM,Lee T

更新日期：2005-11-01 00:00:00

abstract：:We have previously shown that retinoic acid (RA) has protective effects on high glucose (HG)-induced cardiomyocyte apoptosis. To further elucidate the molecular mechanisms of RA effects, we determined the interaction between nuclear factor (NF)-κB and RA signaling. HG induced a sustained phosphorylation of IKK/IκBα an...

journal_title：Journal of cellular physiology

authors： Nizamutdinova IT,Guleria RS,Singh AB,Kendall JA Jr,Baker KM,Pan J

更新日期：2013-02-01 00:00:00

abstract：:Cultured bovine aortic endothelial cells were fixed and stained with NBD-phallicidin and quantitated with a digital image analyzer for changes in actin cables and surface area. Serotonin (5-HT), norepinephrine (NE), dopamine and histamine (all at 10(-4)M concentrations) were tested for their ability to induce cytoskel...

journal_title：Journal of cellular physiology

authors： Welles SL,Shepro D,Hechtman HB

更新日期：1985-06-01 00:00:00

abstract：:Arterial smooth muscle cells undergo marked biochemical and morphological changes upon culturing. We have studied the time course of these changes in smooth muscle cells isolated from normal rabbit aortas by enzymic digestion and then maintained in Dulbecco's modified Eagle's medium with or without 10% rabbit serum. S...

journal_title：Journal of cellular physiology

authors： Yau-Young AO,Shio H,Fowler S

更新日期：1981-09-01 00:00:00

abstract：:Release of transcellular tension upon disruption of actin stress fibers with cytochalasin D (CD) and associated changes in cell morphology are reflected in the rapid transcription of "deformation-responsive" genes. For certain genes (e.g., urokinase plasminogen activator and its type-1 inhibitor PAI-1), de novo mRNA s...

journal_title：Journal of cellular physiology

authors： Samarakoon R,Higgins PJ

更新日期：2003-06-01 00:00:00

abstract：:Fibroblast growth factor-2 (FGF-2) stimulates periodontal regeneration by a broad spectrum of effects on periodontal ligament (PDL) cells, such as proliferation, migration, and production of extracellular matrix. A critical factor in the success of periodontal regeneration is the rapid resolution of inflammatory respo...

journal_title：Journal of cellular physiology

authors： Fujihara C,Kanai Y,Masumoto R,Kitagaki J,Matsumoto M,Yamada S,Kajikawa T,Murakami S

更新日期：2019-05-01 00:00:00

abstract：:Obese women offspring have a higher risk of developing chronic diseases associated with an altered immune function. We aim to determine, in neonatal monocyte-derived macrophages, whether maternal obesity is associated with an altered expression and DNA methylation of pro- and anti-inflammatory genes, along with a high...

journal_title：Journal of cellular physiology

authors： Cifuentes-Zúñiga F,Arroyo-Jousse V,Soto-Carrasco G,Casanello P,Uauy R,Krause BJ,Castro-Rodríguez JA

更新日期：2017-12-01 00:00:00

abstract：:Overexpression of IGF-1 in C2C12 myoblasts causes hypertrophy when myoblasts fuse to form myotubes, a response that requires elevated intracellular calcium. We show that myoblasts contain a store-operated Ca2+ channel (SOCC) whose activity is enhanced with IGF-1 overexpression. A membrane protein, CD20, can cause Ca2+...

journal_title：Journal of cellular physiology

authors： Ju YK,Wu MJ,Chaulet H,Marciniec T,Graham RM,Allen DG

更新日期：2003-10-01 00:00:00

abstract：:Osteoclasts and macrophages share progenitors that must receive decisive lineage signals driving them into their respective differentiation routes. Macrophage colony stimulation factor M-CSF is a common factor; bone is likely the stimulus for osteoclast differentiation. To elucidate the effect of both, shared mouse bo...

journal_title：Journal of cellular physiology

authors： De Vries TJ,Schoenmaker T,Aerts D,Grevers LC,Souza PP,Nazmi K,van de Wiel M,Ylstra B,Lent PL,Leenen PJ,Everts V

更新日期：2015-01-01 00:00:00

abstract：:The permeability of human platelets to glycerol was determined at 37 degrees C, 25 degrees C, and 0 degrees C from the rate of change of cell volume after abrupt addition of 0.5 mol/liter glycerol in phosphate-buffered saline. Intracellular water volume was measured employing both tritiated water and a photometric met...

journal_title：Journal of cellular physiology

authors： Armitage WJ

更新日期：1986-07-01 00:00:00