Galactosyltransferase activity and cell growth: uridine diphosphate (UDP)galactose inhibition of murine leukemic L1210 cells.

abstract：:Members of the transforming growth factor-β (TGF-β) family of cytokines are involved in diverse physiological processes. Although TGF-β is known to play multiple roles in the mammalian central nervous system (CNS), its role in neuronal development has not been explored. We have studied the effects of TGF-β1 on the ele...

journal_title：Journal of cellular physiology

authors： Zhuang JL,Wang CY,Zhou MH,Duan KZ,Mei YA

更新日期：2012-01-01 00:00:00

abstract：:Osteoblasts are terminally differentiated cells with mesenchymal origins, known to possess pivotal roles in sustaining bone microstructure and homeostasis. These cells are implicated in the pathophysiology of various bone disorders, especially osteoporosis. Over the last few decades, strategies to impede bone resorpti...

journal_title：Journal of cellular physiology

authors： Aslani S,Abhari A,Sakhinia E,Sanajou D,Rajabi H,Rahimzadeh S

更新日期：2019-06-01 00:00:00

abstract：:L-Arginine transport and nitric oxide (NO) synthesis (L-arginine/NO pathway) are stimulated by insulin, adenosine or elevated extracellular D-glucose in human umbilical vein endothelial cells (HUVEC). Adenosine uptake via the human equilibrative nucleoside transporters 1 (hENT1) and 2 (hENT2) has been proposed as a me...

journal_title：Journal of cellular physiology

authors： Muñoz G,San Martín R,Farías M,Cea L,Vecchiola A,Casanello P,Sobrevia L

更新日期：2006-12-01 00:00:00

abstract：:We have observed that some of the DNA damage or damage product caused by irradiation of interphase cells persisted throughout the cell cycle, and resulted in the expression of gamma-H2AX foci on the mitotic chromosomes. These mitotic expressions of damage after gamma-irradiation of G1 or G2 phase cells were compared i...

journal_title：Journal of cellular physiology

authors： Kato TA,Okayasu R,Bedford JS

更新日期：2009-06-01 00:00:00

abstract：:Adiponectin, one of the adipose-derived hormone with metabolic activity, has been reported to conversely affect angiogenesis of endothelial cells in vitro. The previous study in animal models has demonstrated that adiponectin has a protective role in retinal vascular injury following pathological stimuli. However, cli...

journal_title：Journal of cellular physiology

authors： Li R,Du J,Yao Y,Yao G,Wang X

更新日期：2019-11-01 00:00:00

abstract：:RB loss has long been recognized as the causative genetic alteration underlying retinoblastoma but it is increasingly evident that other alterations are required for the tumor to develop. Therefore, we set out to identify additional inheritable susceptibility markers and new potential preventive and therapeutic target...

journal_title：Journal of cellular physiology

authors： Indovina P,Acquaviva A,De Falco G,Rizzo V,Onnis A,Luzzi A,Giorgi F,Hadjistilianou T,Toti P,Tomei V,Pentimalli F,Carugi A,Giordano A

更新日期：2010-04-01 00:00:00

abstract：:Although glucocorticoids strongly affect numerous biological processes including cell growth, development, and homeostasis, their effects on migration of human mesenchymal stem cells (hMSCs) are unclear. Therefore, we investigated the role of dexamethasone (DEX) and its related signaling pathways on migration of hMSCs...

journal_title：Journal of cellular physiology

authors： Yun SP,Ryu JM,Han HJ

更新日期：2011-03-01 00:00:00

abstract：:Alkaptonuria (AKU) is a rare disease correlated with deficiency of the enzyme homogentisate 1,2 dioxygenase, which causes homogentisic acid (HGA) accumulation. HGA is subjected to oxidation/polymerization reactions, leading to the production of a peculiar melanin-like pigmentation (ochronosis) after chronic inflammati...

journal_title：Journal of cellular physiology

authors： Schiavone ML,Millucci L,Bernardini G,Giustarini D,Rossi R,Marzocchi B,Santucci A

更新日期：2020-10-01 00:00:00

abstract：:Cholangiocarcinoma (CCA) is a mortal cancer with gradually increasing incidences all over the world, whereas effective diagnosis and treatment for this disease are still lacking. As a classical long noncoding RNA (lncRNA), maternally expressed gene 3 (MEG3) has been reported to exhibit pivotal regulatory roles in the ...

journal_title：Journal of cellular physiology

authors： Li J,Jiang X,Li C,Liu Y,Kang P,Zhong X,Cui Y

更新日期：2019-12-01 00:00:00

abstract：:The epidermal growth factor (EGF) receptor interacts with structural elements of A431 cells and remains associated with the cytoskeleton following extraction with nonionic detergents. Extraction of cells with 0.15% Triton X-100 resulted in detection of only approximately 40% of the EGF binding sites on the cytoskeleto...

journal_title：Journal of cellular physiology

authors： Roy LM,Gittinger CK,Landreth GE

更新日期：1991-01-01 00:00:00

abstract：:Scatchard analysis of binding of 125I-basic fibroblast growth factor (FGF) to baby hamster kidney (BHK) cells revealed the presence of two binding sites: a high affinity site with KD of 20 pM and 80,000 sites per cell and a low affinity site with KD of about 2 nM and 600,000 sites per cell. The binding to the two site...

journal_title：Journal of cellular physiology

authors： Moscatelli D

更新日期：1987-04-01 00:00:00

abstract：:Curcumin is known to be a potent wound healer. Despite this, studies on curcumin using certain model systems have shown it to be anti-angiogenic. Results of the present investigations suggest that curcumin causes opposing effects on angiogenesis in serum stimulated and unstimulated conditions. The evidence in support ...

journal_title：Journal of cellular physiology

authors： Kiran MS,Kumar VB,Viji RI,Sherin GT,Rajasekharan KN,Sudhakaran PR

更新日期：2008-04-01 00:00:00

abstract：:Hedgehog (Hh) family members are involved in multiple cellular processes including proliferation, migration, differentiation, and cell fate determination. Recently, the novel Hh agonists Hh-Ag 1.3 and 1.7 were identified in a high-throughput screening of small molecule compounds that activate the expression of Gli1, a...

journal_title：Journal of cellular physiology

authors： Nakamura T,Naruse M,Chiba Y,Komori T,Sasaki K,Iwamoto M,Fukumoto S

更新日期：2015-04-01 00:00:00

abstract：:The aim of our studies was to identify miRNAs affecting the release of the major ovarian steroid hormones progestagen, androgen and estrogen by human ovarian cells. The effect of transfection of cultured primary ovarian granulosa cells with 80 different gene constructs encoding human pre-miRNAs on release of progester...

journal_title：Journal of cellular physiology

authors： Sirotkin AV,Ovcharenko D,Grossmann R,Lauková M,Mlyncek M

更新日期：2009-05-01 00:00:00

abstract：:Males and females differ across a broad spectrum of morphological, physiological, and behavioral characters. In fact, sexually dimorphic traits typically contribute the largest component of phenotypic variance in most taxa that use sex to reproduce. However, we know very little about the mechanisms that maintain these...

journal_title：Journal of cellular physiology

authors： Rigby N,Kulathinal RJ

更新日期：2015-10-01 00:00:00

abstract：:Thymosin β4 (Tβ4), a G-actin-sequestering secreted peptide, improves neurovascular remodeling and central nervous system plasticity, which leads to neurological recovery in many neurological diseases. Inflammatory response adjustment and tissue inflammation consequences from neurological injury are vital for neurologi...

journal_title：Journal of cellular physiology

authors： Shomali N,Baradaran B,Deljavanghodrati M,Akbari M,Hemmatzadeh M,Mohammadi H,Jang Y,Xu H,Sandoghchian Shotorbani S

更新日期：2020-04-01 00:00:00

abstract：:Prostate cancer (PCa) is the second leading cause of death among American men. Increasing evidence has shown that long noncoding RNAs (lncRNAs) play important roles in tumorigenesis of PCa. In this study, we explored the biological functions of small nucleolar RNA host gene 12 (SNHG12) and investigated the interaction...

journal_title：Journal of cellular physiology

authors： Cheng G,Song Z,Liu Y,Xiao H,Ruan H,Cao Q,Wang K,Xiao W,Xiong Z,Liu D,Chen K,Zhang X

更新日期：2020-02-01 00:00:00

abstract：:Despite the improvements in fracture healing, about 10% of patients undergo abnormal healing. As a tumor suppressor, upregulation of microRNA (miR)-203 has been observed in osteogenic differentiation. Herein, we aimed to explore the functional role of miR-203 in osteoblasts as well as the underlying mechanisms. The ex...

journal_title：Journal of cellular physiology

authors： Liu H,Chen B,Li Y

更新日期：2019-08-01 00:00:00

abstract：:The toxicity of cationic fluorescent dye, rhodamine 123, towards a number of independently established cell lines from three different species, namely human, mouse, and Chinese hamster, has been examined. All of the cell lines from any one species that were examined were found to exhibit similar sensitivities towards ...

journal_title：Journal of cellular physiology

authors： Gupta RS,Dudani AK

更新日期：1987-03-01 00:00:00

abstract：:Neuropathic pain (NP) may cause serious brain diseases, but the genes associated with the metabolic pathway and transcript factors of NP remain unclear. This study is aimed to identify the therapy target genes for NP and to investigate the metabolic pathways and transcript factors associated with NP. The differentiall...

journal_title：Journal of cellular physiology

authors： Yan XT,Xu Y,Cheng XL,He XH,Wang Y,Zheng WZ,Zhao Y,Chen H,Wang YL

更新日期：2019-05-01 00:00:00

abstract：:The present study was to investigate the effects and action mechanisms of digoxin and ouabain on steroidogenesis in human adrenocortical NCI-H295 cells. Administration of digoxin or ouabain for 24 h decreased the basal and angiotensin II (Ang II)-stimulated release of aldosterone by NCI-H295 cells. The conversions of ...

journal_title：Journal of cellular physiology

authors： Kau MM,Kan SF,Wang JR,Wang PS

更新日期：2005-12-01 00:00:00

abstract：:Primary porcine choroid plexus epithelial cells cultivated in chemically defined medium maintain their epithelial characteristics and form confluent monolayers. They produce a fluid the composition of which resembles cerebrospinal fluid. The present study demonstrates constitutive secretion of large amounts of beta-tr...

journal_title：Journal of cellular physiology

authors： Hoffmann A,Gath U,Gross G,Lauber J,Getzlaff R,Hellwig S,Galla HJ,Conradt HS

更新日期：1996-11-01 00:00:00

abstract：:We report that cultured vascular endothelial cells release into the culture medium a vasoconstrictor peptide, a substance we call an endothelium-derived constricting factor (EDCF). Conditioned medium from cultured bovine aortic and pulmonary artery endothelial cells caused sustained, dose-dependent isometric constrict...

journal_title：Journal of cellular physiology

authors： O'Brien RF,Robbins RJ,McMurtry IF

更新日期：1987-08-01 00:00:00

abstract：:Drug discovery is an onerous, extremely expensive, and time-consuming process. Instead, drug repurposing is an attractive strategy for exploiting novel indications for a drug beyond its original use. The untapped potential of drug repurposing compensates the barriers associated with the drug discovery pipeline. Psoria...

journal_title：Journal of cellular physiology

authors： Thatikonda S,Pooladanda V,Godugu C

更新日期：2020-06-01 00:00:00

abstract：:We have previously demonstrated that the rate of fluid shear stress (ΔSS) can manipulate the fate of mesenchymal stem cells (MSCs) to osteogenic or chondrogenic cells. However, whether ΔSS is comparable to other two means of induction medium and substrate stiffness that have been proven to be potent in differentiation...

journal_title：Journal of cellular physiology

authors： Yue D,Zhang M,Lu J,Zhou J,Bai Y,Pan J

更新日期：2019-02-19 00:00:00

abstract：:A method, based on the differing capacities of cells to adhere to a column of polyester fibres, has been described for separating human bone marrow cells into a nonadherent and an adherent fraction. The effect of this cell separation procedure on colony formation by erythroid progenitor cells was investigated. In cont...

journal_title：Journal of cellular physiology

authors： Aye MT

更新日期：1977-04-01 00:00:00

abstract：:Acetylcholine (ACh) protected against cardiac injury via promoting autophagy and mitochondrial biogenesis, however, the involvement of mitophagy in ACh-elicited cardioprotection remains unknown. In the present study, H9c2 cardiomyocytes were subjected to hypoxia/reoxygenation (H/R) and ACh treatment during reoxygenati...

journal_title：Journal of cellular physiology

authors： Sun L,Zhao M,Yang Y,Xue RQ,Yu XJ,Liu JK,Zang WJ

更新日期：2016-05-01 00:00:00

abstract：:Considerable evidence has accumulated for a role of a nonsteroidal mevalonate product in the regulation of DNA replication and cell division. We report here a similar requirement for mevalonate in a nonreplicative function, that of natural killer (NK) cell cytotoxicity. Treatment of NK cells with 10 microM compactin f...

journal_title：Journal of cellular physiology

authors： Cutts JL,Scallen TJ,Watson J,Bankhurst AD

更新日期：1989-06-01 00:00:00

abstract：:Heat shock factors (HSFs) are the main transcriptional regulators of the stress-induced expression of heat shock protein genes. HSF2, which is one of the HSFs, is activated during differentiation and development but it is unclear how they regulate during cellular processes. Here, we examined the role of HSF4a on the r...

journal_title：Journal of cellular physiology

authors： Kim SA,Yoon JH,Ahn SG

更新日期：2012-01-01 00:00:00

abstract：:Excessive generation of mitochondrial reactive oxygen species (ROS) is considered to be initiating event in the development of diabetic nephropathy (DN). Mitochondrial biosynthesis mediated by coactivator PGC-1α and its downstream transcription factors NRF1 and TFAM may be a key target in maintaining mitochondrial fun...

journal_title：Journal of cellular physiology

authors： Zhang T,Chi Y,Kang Y,Lu H,Niu H,Liu W,Li Y

更新日期：2019-04-01 00:00:00