The association of D-group chromosomal translocations and defective spermatogenesis.

Abstract:

:D-group chromosome translocations have been associated in isolated cases with infertility in males. In this study, we demonstrated the effect of a translocated D-group chromosome on spermatogenesis as it had segregated among three male members of one family. Although the father, who carried the translocation, was obviously fertile, the effects of the translocations on his sperm were noted in the morphologic examination. This study demonstrates the need for more careful evaluation of patients with chromosomal abnormalities for effects on spermatogenesis. Furthermore, it shows the possibility of autosomal chromosomal influences on testicular function.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Plymate SR,Bremner WJ,Paulsen CA

doi

10.1016/s0015-0282(16)41651-1

keywords:

subject

Has Abstract

pub_date

1976-02-01 00:00:00

pages

139-44

issue

2

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)41651-1

journal_volume

27

pub_type

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