Kushta(s): unique herbo-mineral preparations used in South Asian traditional medicine.

abstract：:The Sudden Infant Death Syndrome (SIDS) is responsible for the death of 10,000 infants annually in the U.S.A. The cause of these deaths is not known; all SIDS infants studied died during sleep in a silent fashion and there are no specific lesions observable post mortem. It may be of significance, however, that nearly ...

journal_title：Medical hypotheses

authors： Reid GM

更新日期：1987-03-01 00:00:00

abstract：:Obstructive sleep apnea (OSA) is a common and underdiagnosed medical disorder. OSA is associated with the symptoms of excessive daytime sleepiness (EDS). These patients typically follow a sedentary lifestyle, and sedentary behavior is related to impaired fluid dynamics in the lower body, particularly the legs. In a su...

journal_title：Medical hypotheses

authors： Mirrakhimov AE

更新日期：2013-02-01 00:00:00

abstract：:Computer algorithms can only produce seemingly random or pseudorandom numbers whereas certain natural phenomena, such as the decay of radioactive particles, can be utilized to produce truly random numbers. In this study, the ability of humans to generate random numbers was tested in healthy adults. Subjects were simpl...

journal_title：Medical hypotheses

authors： Persaud N

更新日期：2005-01-01 00:00:00

abstract：:The cause and therapy of neurodegenerative diseases remain unsolved puzzles. These diseases are correlated with presence of beta sheet-rich amyloid assemblies. Here, I derive and assemble puzzle pieces to obtain a loose end-tying hypothesis for cause with direct implications for therapy. I use the following extrapolat...

journal_title：Medical hypotheses

authors： Serwer P

更新日期：2018-01-01 00:00:00

abstract：:It is proposed that there is biological regulation of the low molecular weight antioxidant (LMWA) status of the body, and that these different antioxidants work in concert and in homeostasis as a system analogous to the regulation of acid-base status (pH). The theoretical design characteristics for such a system inclu...

journal_title：Medical hypotheses

authors： Berry EM,Kohen R

更新日期：1999-11-01 00:00:00

abstract：:Despite the fact that antidepressants represent the gold standard for the treatment of depression, not all patients treated with an antidepressant monotherapy achieve complete remission of depressive symptoms and functional recovery. Therefore, further examination of the components that may be involved in the action m...

journal_title：Medical hypotheses

authors： Pae CU,Lee C,Paik IH

更新日期：2007-01-01 00:00:00

abstract：:Chronic stresses can induce physiological and psychological changes and result in stress-related neuropsychiatry, sometimes they may also contribute to hypersensitivity to pain known as stress-induced hyperalgesia (SIH). Recently it was found that GABAergic disinhibition is closely related to morphine and chronic infl...

journal_title：Medical hypotheses

authors： Dai S,Ma Z

更新日期：2014-12-01 00:00:00

abstract：:Both epidemiological and experimental studies have shown that impaired growth in utero due to maternal malnutrition, resulting in low birth weight, is associated with a high incidence of glucose intolerance, insulin resistance, and type 2 diabetes in adult life. Maternal malnutrition is a worldwide problem and unavoid...

journal_title：Medical hypotheses

authors： Ende N,Reddi AS

更新日期：2006-01-01 00:00:00

abstract：:Despite aggressive intervention, patients who survive an out-of-hospital cardiac arrest (OHCA) generally have very poor prognoses, with nationwide survival rates of approximately 10-20%. Approximately 90% of survivors will have moderate to severe neurological injury ranging from moderate cognitive impairment to brain ...

journal_title：Medical hypotheses

authors： Gul SS,Huesgen KW,Wang KK,Mark K,Tyndall JA

更新日期：2017-08-01 00:00:00

abstract：:The existence of homosexuality in humans poses a problem for evolutionary theory. Exclusive male homosexuality has a catastrophic effect on reproduction and yet inherited factors appear to contribute to it. Previous attempts to resolve this conundrum are inconsistent with aspects of evolutionary theory. Additional lim...

journal_title：Medical hypotheses

authors： Dewar CS

更新日期：2003-02-01 00:00:00

abstract：:Primary hyperparathyroidism is one of the most common causes of hypercalcemia. Most cases result from sporadic benign monoclonal adenomas or hyperplasia. Increased body weight is consistently present in cohorts of patients with primary hyperparathyroidism. It has been shown that fat mass is the major determinant of se...

journal_title：Medical hypotheses

authors： Cheng SP,Doherty GM,Chang YC,Liu CL

更新日期：2011-01-01 00:00:00

abstract：:An immune modulation complex is proposed which recognizes and is driven by an MHC presented epitope of the CD4 molecule present on the surface of up regulated CD4+ lymphocytes. Immune modulation is affected by both CD4 lymphocyte destruction and impairment of their potential for immune recognition. These two processes...

journal_title：Medical hypotheses

authors： Kennedy JR

更新日期：1993-11-01 00:00:00

abstract：:According to the theory presented herewith, neoplasia results solely from stem cell depletion. Besides serving as tissue progenitors, stem cells are postulated to secrete a vital substance 'A' necessary for proper tissue function. Carcinogens interfere with 'A' production mainly by destroying stem cells and since the ...

journal_title：Medical hypotheses

authors： Zajicek G

更新日期：1985-11-01 00:00:00

abstract：:We have formalized extracellular and intracellular volume interaction with each other and the influence of these processes on the type of cell growth. The linearized model was verified by stereo metric solution and the results were compared with experimental data. Two theoretical solutions were found: Solution 1, extr...

journal_title：Medical hypotheses

authors： Hajek D,Kolar P,Maini PK,Starha P

更新日期：2005-01-01 00:00:00

abstract：:It has been uncovered that expansion of trinucleotide repeats in the human genome are causing a variety of genetic diseases. They are also identified in other loci that are not clearly related to particular diseases, which indicates such repeat expansion is one of the general forms of evolution occurring throughout th...

journal_title：Medical hypotheses

authors： Kubota S

更新日期：2001-03-01 00:00:00

abstract：:The etiology of most kinds of dementia is still obscure and is probably multifactorial. We query whether excessive watching of television may contribute to the development of dementive processes for the following reasons: TV spectators are exposed to a mass of successive and rapid stimuli with little or no possibility...

journal_title：Medical hypotheses

authors： Aronson M

更新日期：1993-11-01 00:00:00

abstract：:A hypothesis which explains disease prevalence among different socio-economic groups following early infantile modulation of cell-mediated immunity by infection and nutrition related stress is presented. Wealthy populations living under highly hygienic circumstances can develop their cell-mediated immunity to genetic ...

journal_title：Medical hypotheses

authors： Dutz W

更新日期：1975-11-01 00:00:00

abstract：:Tumor cells have an absence or deficiency of mitochondrial superoxide dismutase. Superoxide is produced when hematoporphyrin derivative is exposed to visible light. A significant portion of the antitumor effect of porphyrin:light therapy is hypothesized to be mediated by superoxide. ...

journal_title：Medical hypotheses

authors： Peterson DA,McKelvey S,Edmondson PR

更新日期：1981-02-01 00:00:00

abstract：:Chronic viral liver disease may evolve to cirrhosis. The medical treatment to slow down this passage is based on anti-viral and anti-fibrotic properties of interferon. Recently, we evidenced significant increase of portal vein flow velocity and volume after a prostacyclin analog (iloprost) infusion in subjects without...

journal_title：Medical hypotheses

authors： Zardi EM,Vespasiani Gentilucci U,Picardi A,Ambrosino G,Fazio VM,Dobrina A,Afeltra A

更新日期：2005-01-01 00:00:00

abstract：:Multiple sclerosis remains a rare neurological disease of unknown aetiology, with a unique distribution, both geographically and historically. Rare in equatorial regions, it becomes increasingly common in higher latitudes; historically, it was first clinically recognized in the early nineteenth century. A hypothesis, ...

journal_title：Medical hypotheses

authors： Carlyle IP

更新日期：1997-12-01 00:00:00

abstract：:Meditation is used worldwide by millions of people for relaxation and stress relief. Given sufficient practice, meditators may also experience a variety of altered states of consciousness. These states can lead to a variety of unusual experiences, including physical, emotional and psychic disturbances. This paper high...

journal_title：Medical hypotheses

authors： Lindsay S

更新日期：2014-10-01 00:00:00

abstract：:Many clinical trials have clearly demonstrated the benefit of statins in the prevention of coronary heart disease. Although other effects have subsequently been described, the so-called pleiotropic effects of statins, there is a tendency to relate all those effects, more or less directly, to inhibition of 3-hydroxy-3-...

journal_title：Medical hypotheses

authors： Negrão MR,Mota A,Azevedo I,Martins MJ

更新日期：2006-01-01 00:00:00

abstract：:Neuromyelitis optica (NMO) is an uncommon, life-threatening demyelinating disease that produces transverse myelitis and optic neuritis. An important pathogenetic mechanism belongs to NMO-IgG autoantibodies directed against the ultrastructure of the water channel aquaporin-4 (AQP4), the so-called orthogonal arrays of p...

journal_title：Medical hypotheses

authors： Warth A

更新日期：2009-09-01 00:00:00

abstract：:Idiopathic intracranial hypertension (IHH or pseudotumor cerebri) is an uncommon but important cause of headache, characterized by raised intracranial pressure (ICP) in the absence of infection and intracranial pathology on neuroimaging. Lumbar puncture (LP) is usually contra-indicated in situations where the ICP is s...

journal_title：Medical hypotheses

authors： Salman M

更新日期：1999-10-01 00:00:00

abstract：:Diabetes is a global public health challenge that imposes heavy burdens on communities and individuals. Metformin, the first-line medication for diabetes, has the superiority of reducing risk of macrovascular diseases, all-cause mortality and even possibly cancers. Recent observational studies, however, have demonstra...

journal_title：Medical hypotheses

authors： Xu L,Huang Z,He X,Wan X,Fang D,Li Y

更新日期：2013-08-01 00:00:00

abstract：:Diabetes mellitus, a metabolic disorder with significant global health care burden, causes chronic microvascular and macrovascular complications that still comprise a therapeutic challenge. Angiotensin-(1-7), a heptapeptide with vasodilatory properties, has been found to restore vascular reactivity and endothelial cel...

journal_title：Medical hypotheses

authors： Kibel A

更新日期：2016-08-01 00:00:00

abstract：:This paper compares two models of the sense of smell and demonstrates that the new model has advantages over the accepted model with implications for medical research. The accepted transduction model had an odourant or pheromone contacting an aqueous sensory lymph then movement through it to a receptor membrane beneat...

journal_title：Medical hypotheses

authors： Nicholson B

更新日期：2001-09-01 00:00:00

abstract：:Recurrent Aphthous Stomatitis (RAS) is the most common ulcerative diseases of oral mucosa affecting an estimate of 20% of the world's population. Majority of the people affected by RAS are under 30 years of age. RAS is located on the lining (non-keratinized) oral mucosa, i.e. buccal mucosa, lateral side of the tongue,...

journal_title：Medical hypotheses

authors： Pärssinen M,Jäsberg H,Mikkonen JJW,Kullaa AM

更新日期：2021-01-01 00:00:00

abstract：:In mathematics and physics, chaos theory deals with the behavior of certain nonlinear dynamical systems that under certain conditions exhibit a phenomenon known as chaos, which is characterised by a sensitivity to initial conditions. Mathematicians paradoxically call such states of order chaos and distinguish them fro...

journal_title：Medical hypotheses

authors： Zifan A,Gharibzadeh S

更新日期：2006-01-01 00:00:00

abstract：:As human society is mainly cooperative, it is not clear how antisocial personality disorder (APD) persists. The current explanation is that sociopaths are cheaters who maximize their fitness by taking advantages from others. Although this argument is valid, we show here that society also benefits from APD. We propose ...

journal_title：Medical hypotheses

authors： Miric D,Hallet-Mathieu AM,Amar G

更新日期：2005-01-01 00:00:00