Stimulation in the rat fastigial nucleus enhances the responses of neurons in the dorsal column nuclei to innocuous stimuli.

abstract：:Both autoradiographic and horseradish peroxidase tracing techniques were used to characterize a projection from the dorsal lateral geniculate (DLG) nucleus of the thalamus to visual association cortex (extrastriate cortex) in the macaque monkey. The results show that medium to large caliber DLG axons end to discontinu...

journal_title：Neuroscience letters

authors： Yoshida K,Benevento LA

更新日期：1981-03-10 00:00:00

abstract：:After hypoxic-ischemic insult iron deposited in the brain catalyzes formation of reactive oxygen species. Newborn rats, showing reduced physiological body temperature and their hyperthermic counterparts injected with deferoxamine (DF), a chelator of iron, are protected both against iron-mediated neurotoxicity and agai...

journal_title：Neuroscience letters

authors： Kletkiewicz H,Nowakowska A,Siejka A,Mila-Kierzenkowska C,Woźniak A,Caputa M,Rogalska J

更新日期：2016-08-15 00:00:00

abstract：:Although corticotropin-releasing factor (CRF) is thought to act as a neurotransmitter to activate the locus coeruleus (LC) during hypotensive stress, the consequences of LC activation by CRF are unknown. In the present study a hypotensive challenge that activated rat LC neurons also produced cortical electroencephalog...

journal_title：Neuroscience letters

authors： Page ME,Berridge CW,Foote SL,Valentino RJ

更新日期：1993-12-24 00:00:00

abstract：:The whole-cell configuration of the patch-clamp technique was applied to porcine pars intermedia cells. A tetrodotoxin-sensitive sodium current was recorded. Three types of calcium current were observed. Depolarizations from a holding potential of 100 mV elicited a transient current (ICaT), whereas depolarizations fro...

journal_title：Neuroscience letters

authors： Taleb O,Trouslard J,Demeneix BA,Feltz P

更新日期：1986-05-06 00:00:00

abstract：:A pronounced decrease in dopamine content in both the striatum and the mesolimbic area was observed up to 120 days of age after treatment with 6-hydroxydopamine (100 micrograms, intracisternally) following desipramine pretreatment (20 mg/kg, i.p.) at the 5th postnatal day. In the 6-hydroxydopamine-treated rats, Met-en...

journal_title：Neuroscience letters

authors： Kurumaji A,Takashima M,Watanabe S,Takahashi K

更新日期：1988-04-22 00:00:00

abstract：:Tetrahydroaminoacridine (THA) has recently been reported to be more useful in the treatment of Alzheimer's disease than physostigmine. A comparison of the effects of these two anticholinesterase agents on in vitro enzyme and receptor activities of human cerebral cortex (obtained at autopsy) revealed similarities in th...

journal_title：Neuroscience letters

authors： Perry EK,Smith CJ,Court JA,Bonham JR,Rodway M,Atack JR

更新日期：1988-08-31 00:00:00

abstract：:Precursor cells have been shown to be affected by oxidative stress, in vivo and vitro, but little is known about the expression of antioxidant mechanisms in neuronal/glial differentiation. We have characterized the expression of Cu/Zn superoxide dismutase (Cu/Zn SOD), one of the main antioxidant proteins involved in t...

journal_title：Neuroscience letters

authors： Faiz M,Acarin L,Peluffo H,Villapol S,Castellano B,González B

更新日期：2006-06-19 00:00:00

abstract：:Parkinson's disease (PD) is one of the common neurodegenerative diseases that result in the progressive damage of dopaminergic neurons. Environmental exposure, including paraquat, is considered risky for PD. Epigenetics refer to the study of heritable changes in gene expression that occur without a change in DNA seque...

journal_title：Neuroscience letters

authors： Kong M,Ba M,Liang H,Ma L,Yu Q,Yu T,Wang Y

更新日期：2012-08-22 00:00:00

abstract：:The highest prevalence rate of spinocerebellar ataxia type 6 (SCA6) in the worldwide population is in the Chugoku and Kansai areas of Western Japan, but the reason of this geographic characteristics is unclear. We investigated the predisposing haplotypes and their geographic distribution. Genotyping of five microsatel...

journal_title：Neuroscience letters

authors： Terasawa H,Oda M,Morino H,Miyachi T,Izumi Y,Maruyama H,Matsumoto M,Kawakami H

更新日期：2004-03-25 00:00:00

abstract：:Face processing is unique to human beings and is likely to have special neuronal properties. We studied one of these properties, categorical representation of the face in perception processing (perception) and in memory recall processing (imagery), using the face and building stimuli. The same building-selective areas...

journal_title：Neuroscience letters

authors： Sung YW,Ogawa S

更新日期：2008-12-19 00:00:00

abstract：:The modulation of cutaneomuscular responses in response to mechanical vibration applied to the foot sole and to the ankle tendons was established in ten healthy subjects. The effects of mechanical vibration applied to the skin adjacent to the tibialis anterior (TA) and Achilles tendons were examined in two subjects. W...

journal_title：Neuroscience letters

authors： Smith AC,Mummidisetty CK,Rymer WZ,Knikou M

更新日期：2013-06-17 00:00:00

abstract：:In this study, we investigated two newly reported polymorphisms in association with late onset Alzheimer's disease (AD) in Chinese. They were a -491 A/T polymorphism in the Apolipoprotein E (APOE) promoter region and a five base pair deletion at exon 18 of alpha2-Macroglobin (A2M). There were 196 AD and 180 normal con...

journal_title：Neuroscience letters

authors： Chen L,Baum L,Ng HK,Chan LY,Sastre I,Artíga MJ,Valdivieso F,Bullido MJ,Chiu HF,Pang CP

更新日期：1999-07-16 00:00:00

abstract：:Acrolein-induced oxidative stress is hypothesized to involve in the etiology of Alzheimer's disease (AD). Caffeic acid (CA) and caffeic acid phenethyl ester (CAPE) have antioxidative and neuroprotective properties. The present study investigated the protective effects of CA/CAPE on acrolein-induced oxidative neuronal ...

journal_title：Neuroscience letters

authors： Huang Y,Jin M,Pi R,Zhang J,Chen M,Ouyang Y,Liu A,Chao X,Liu P,Liu J,Ramassamy C,Qin J

更新日期：2013-02-22 00:00:00

abstract：:The pituitary-adrenal responsiveness to a mild stressor was assessed in rats that were deprived of paradoxical sleep (PS) and in controls that were not deprived. Animals were either individually- or group-deprived for 96 h and hormone levels were assessed at 0, 5, 20 or 60 min after a saline injection+novelty and comp...

journal_title：Neuroscience letters

authors： Suchecki D,Tiba PA,Tufik S

更新日期：2002-03-01 00:00:00

abstract：:Single electrode voltage-clamp recording from CA3 neurons in guinea pig hippocampal slices was applied to study effects of a new GABAB antagonist, CGP 55845A, on (-)baclofen (IBac)- or gamma-aminobutyric acid (IGABA)-induced potassium (K)-currents and on inhibitory postsynaptic K-currents (K-IPSCs) recorded in the pre...

journal_title：Neuroscience letters

authors： Jarolimek W,Demmelhuber J,Bijak M,Misgeld U

更新日期：1993-05-14 00:00:00

abstract：:Nucleus rostrolateralis is a distinctive diencephalic nucleus in some ray-finned fishes. In the osteoglossomorph Pantodon, it is a large ovoid nucleus with visual system connections. A topologically and cytoarchitectonically similar nucleus has been found in six species of non-osteoglossomorph fishes, two species of g...

journal_title：Neuroscience letters

authors： Saidel WM,Butler AB

更新日期：1997-06-20 00:00:00

abstract：:Autism spectrum disorders are characterized by impaired social and communication skills and seem to result from altered neural development. We sought to determine whether the anatomy of the meninges and extracellular matrix (ECM) is altered in an animal model of autism, the BTBR T+ tf/J mouse. This mouse displays whit...

journal_title：Neuroscience letters

authors： Mercier F,Cho Kwon Y,Kodama R

更新日期：2011-07-12 00:00:00

abstract：:The distribution of substance P (SP)-like immunoreactivity in the rat retina was investigated by immunohistochemistry. SP-positive cells were found throughout the retina. The majority of them were located in the proximal portion of the inner nuclear layer and the processes from these cells directed to the inner plexif...

journal_title：Neuroscience letters

authors： Fukuda M,Kuwayama Y,Shiosaka S,Ishimoto I,Shimizu Y,Takagi H,Inagaki S,Sakanaka M,Semba E,Takatsuki K,Tohyama M

更新日期：1981-05-29 00:00:00

abstract：:The neurotoxicity of the glutamate receptor agonists N-methyl-D-aspartate (NMDA), (+/-)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA), and kainate was quantitatively assessed in murine spinal cord and cortical cultures prepared under identical conditions. Compared with cortical neurons, spinal neuron...

journal_title：Neuroscience letters

authors： Regan RF

更新日期：1996-07-26 00:00:00

abstract：:Dependency of taste buds and taste papillae on innervation has been debated for a long time. Previous research showed neurotrophins, brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3), play an important role for the establishment of the lingual gustatory and somatosensory innervation. BDNF null mutant ...

journal_title：Neuroscience letters

authors： Ito A,Nosrat IV,Nosrat CA

更新日期：2010-03-08 00:00:00

abstract：:Reduced oxidative demand or neuronal hypometabolism is a neuroprotective strategy used by several anoxia and hypoxia-tolerant species. The epaulette shark, Hemiscyllium ocellatum inhabits shallow reef platforms that can become hypoxic. Hypoxic pre-conditioning (eight cycles of 0.34 mg O(2)/l for 120 min, 12 h apart) w...

journal_title：Neuroscience letters

authors： Mulvey JM,Renshaw GM

更新日期：2000-08-18 00:00:00

abstract：:We studied the topographical distribution of laser sensory thresholds on the human hairy skin, using a small laser beam for pinprick and a large beam for warmth sensations. The threshold for pinprick sensation correlated positively with the distance from the brain, suggesting that Adelta nociceptors, the fibers which ...

journal_title：Neuroscience letters

authors： Agostino R,Cruccu G,Iannetti G,Romaniello A,Truini A,Manfredi M

更新日期：2000-05-12 00:00:00

abstract：:Insulin-like growth factor-1 (IGF1) and its active peptide (1-3)IGF1 modulate brain growth and plasticity and are candidate molecules for treatment of brain disorders. IGF1 N-terminal portion is naturally cleaved to generate the tri-peptide (1-3)IGF1 (glycine-praline-glutamate). IGF1 and (1-3)IGF have been proposed as...

journal_title：Neuroscience letters

authors： Corvin AP,Molinos I,Little G,Donohoe G,Gill M,Morris DW,Tropea D

更新日期：2012-06-27 00:00:00

abstract：:Spasticity in chronic hemiparetic stroke patients has primarily been treated pharmacologically. However, there is increasing evidence that physical rehabilitation can help manage hyper-excitability of reflexes (hyperreflexia), which is a primary contributor to spasticity. In the present study, one chronic hemiparetic ...

journal_title：Neuroscience letters

authors： Hoseini N,Koceja DM,Riley ZA

更新日期：2011-10-24 00:00:00

abstract：:The underlying mechanism of isoflurane-induced cognitive dysfunction in older individuals is unknown. In this study, the effects of isoflurane exposure on the hippocampal blood-brain barrier (BBB) in aged rats were investigated because it was previously shown that BBB disruption involves in cognitive dysfunction. Twen...

journal_title：Neuroscience letters

authors： Cao Y,Ni C,Li Z,Li L,Liu Y,Wang C,Zhong Y,Cui D,Guo X

更新日期：2015-02-05 00:00:00

abstract：:We previously reported that corticotropin-releasing factor (CRF) increased neuronal excitability specifically in type II neurons of the dorsolateral part of the bed nucleus of the stria terminalis (dlBNST). Because the majority of type II dlBNST neurons are thought to be GABAergic interneurons, at least a portion of w...

journal_title：Neuroscience letters

authors： Nagano Y,Kaneda K,Maruyama C,Ide S,Kato F,Minami M

更新日期：2015-07-23 00:00:00

abstract：:The Chronic Constriction Injury of the Infraorbital Nerve (CCI-ION) is a well-established model to study facial sensory changes related to trigeminal neuropathic pain. CCI-ION induces heat hypersensitivity that resolves within 2-3 weeks and a delayed mechanical hypersensitivity that emerges during the second week post...

journal_title：Neuroscience letters

authors： Nones CFM,Claudino RF,Ferreira LEN,Dos Reis RC,King T,Chichorro JG

更新日期：2017-03-22 00:00:00

abstract：:Alternative cleavage of the amyloid precursor protein (APP) results in generation and secretion of both soluble APP (sAPP) and beta-amyloid (Abeta). Abeta is the main component of the amyloid depositions in the brains of Alzheimer's disease (AD) patients. Using Western blotting, we compared the levels of alpha-secreta...

journal_title：Neuroscience letters

authors： Sennvik K,Fastbom J,Blomberg M,Wahlund LO,Winblad B,Benedikz E

更新日期：2000-01-14 00:00:00

abstract：:Prolonged exposure of hippocampal slices to L-glutamate was found to produce a biphasic effect on excitatory synaptic transmission from Schaffer collateral-commissural fibers to CA1 pyramidal neurons: an early blockade of postsynaptic responses was followed by a progressive recovery. Antagonists of N-methyl-D-aspartat...

journal_title：Neuroscience letters

authors： Krishtal OA,Smirnov SV,Osipchuk YuV

更新日期：1988-02-15 00:00:00

abstract：:The placebo effect can be elicited by two main mechanisms: via classical conditioning and cognitive expectations. These two mechanisms have been traditionally investigated in one single domain. The aim of the present study is to investigate how a placebo effect obtained in one modality (pain tolerance) can be transfer...

journal_title：Neuroscience letters

authors： Carlino E,Guerra G,Piedimonte A

更新日期：2016-10-06 00:00:00