Abstract：
:Age-related hearing loss, known as presbyacusis, is characterized by the progressive deterioration of auditory sensitivity associated with aging and is the most common cause of adult auditory deficiency in the United States. Presbyacusis is defined as a progressive, bilateral, high-frequency hearing loss that is manifested on audiometric assessment by a moderately sloping pure tone audiogram. This condition affects approximately 23% of the population between 65 and 75 years of age and 40% of the population older than 75 years of age. In 1980, it was estimated that 11% of the population was 76 years or older and this number is expected to nearly double by the year 2030 [, Otolaryngol. Head Neck Surg. 100, 262]. When coupled with the fact that the population over 65 years of age is experiencing the most rapid progression of hearing loss, the potential socioeconomic ramifications are staggering. Interestingly, presbyacusis varies in its frequency across differing societies. This discrepancy has been attributed to many factors such as genetics, diet, socioeconomic factors, and environmental variables [, Otolaryngol. Head Neck Surg. 100, 266;. Scand. Audiol. 26 (1997) 133]. The purpose of this discussion is to illuminate the various molecular mechanisms underlying this age-related hearing loss and to offer insights into potential ways to mitigate the effects of aging on hearing impairment.
journal_name
Ageing Res Revjournal_title
Ageing research reviewsauthors
Seidman MD,Ahmad N,Bai Udoi
10.1016/s1568-1637(02)00004-1keywords:
subject
Has Abstractpub_date
2002-06-01 00:00:00pages
331-43issue
3eissn
1568-1637issn
1872-9649pii
S1568163702000041journal_volume
1pub_type
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pub_type： 杂志文章,meta分析,评审
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pub_type： 杂志文章,评审
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journal_title：Ageing research reviews
pub_type： 杂志文章
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pub_type： 杂志文章,meta分析,评审
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
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