Review of ICT-based services for identified unmet needs in people with dementia.

Abstract:

:Some of the needs that people with dementia and their informal carers currently perceive as insufficiently met by regular care and support services might be alleviated, or even be met, using modern Information and Communication Technology (ICT). The study described in this paper was designed to provide an insight into the state of the art in ICT solutions that could contribute to meet the most frequently mentioned unmet needs by people with dementia and their informal carers. These needs can be summarized as (1) the need for general and personalized information; (2) the need for support with regard to symptoms of dementia; (3) the need for social contact and company; and (4) the need for health monitoring and perceived safety. Databases that were searched include: PubMed, Cinahl, Psychinfo, Google (Scholar), INSPEC and IEEE. In total 22 websites and 46 publications were included that satisfied the following criteria: the article reports on people with dementia and/or their informal carers and discusses an ICT-device that has been tested within the target group and has proven to be helpful. Within the first need area 18 relevant websites and three studies were included; within the second need area 4 websites and 20 publications were included. Within the third and fourth need area 11 and 12 publications were included respectively. Most articles reported on uncontrolled studies. It is concluded that the informational websites offer helpful information for carers but seem less attuned to the person with dementia and do not offer personalized information. ICT solutions aimed at compensating for disabilities, such as memory problems and daily activities demonstrate that people with mild to moderate dementia are capable of handling simple electronic equipment and can benefit from it in terms of more confidence and enhanced positive effect. Instrumental ICT-support for coping with behavioral and psychological changes in dementia is relatively disregarded as yet, while support for social contact can be effectively realized through, for example, simplified (mobile) phones or videophones or (entertainment) robots. GPS technology and monitoring systems are proven to result in enhanced feelings of safety and less fear and anxiety. Though these results are promising, more controlled studies in which the developed ICT solutions are tested in real life situations are needed before implementing them in the care for people with dementia. It is recommended that future studies also focus on the integration of the current techniques and solutions.

journal_name

Ageing Res Rev

journal_title

Ageing research reviews

authors

Lauriks S,Reinersmann A,Van der Roest HG,Meiland FJ,Davies RJ,Moelaert F,Mulvenna MD,Nugent CD,Dröes RM

doi

10.1016/j.arr.2007.07.002

subject

Has Abstract

pub_date

2007-10-01 00:00:00

pages

223-46

issue

3

eissn

1568-1637

issn

1872-9649

pii

S1568-1637(07)00037-2

journal_volume

6

pub_type

杂志文章,评审
  • Age-related impairment of GM-CSF-induced signalling in neutrophils: role of SHP-1 and SOCS proteins.

    abstract::Functional activities of mature human neutrophils are strongly influenced by the pro-inflammatory cytokine granulocyte macrophage-colony stimulating factor (GM-CSF). Accordingly, a defective response to GM-CSF might have dramatic consequences for neutrophil functions and the host defence against infections. Such an ev...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2006.10.001

    authors: Tortorella C,Simone O,Piazzolla G,Stella I,Antonaci S

    更新日期:2007-08-01 00:00:00

  • COVID-19: risk accumulation among biologically and socially vulnerable older populations.

    abstract::Emerging data show that the health and economic impacts of COVID-19 are being disproportionately borne by individuals who are not only biologically, but also socially vulnerable. Based on preliminary data from Sweden and other reports, in this paper we propose a conceptual framework whereby different factors related t...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2020.101149

    authors: Calderón-Larrañaga A,Dekhtyar S,Vetrano DL,Bellander T,Fratiglioni L

    更新日期:2020-11-01 00:00:00

  • Splicing regulatory factors, ageing and age-related disease.

    abstract::Alternative splicing is a co-transcriptional process, which allows for the production of multiple transcripts from a single gene and is emerging as an important control point for gene expression. Alternatively expressed isoforms often have antagonistic function and differential temporal or spatial expression patterns,...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2017.04.004

    authors: Latorre E,Harries LW

    更新日期:2017-07-01 00:00:00

  • Ataxia-telangiectasia (A-T): An emerging dimension of premature ageing.

    abstract::A-T is a prototype genome instability syndrome and a multifaceted disease. A-T leads to neurodegeneration - primarily cerebellar atrophy, immunodeficiency, oculocutaneous telangiectasia (dilated blood vessels), vestigial thymus and gonads, endocrine abnormalities, cancer predisposition and varying sensitivity to DNA d...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2016.05.002

    authors: Shiloh Y,Lederman HM

    更新日期:2017-01-01 00:00:00

  • Exercise and skeletal muscle ageing: cellular and molecular mechanisms.

    abstract::As we age, our skeletal muscle becomes smaller and weaker. In addition, the remaining muscle is more susceptible to damage, particularly following exercise, recovery from damage is severely impaired and muscle is unable to adapt rapidly following sequential periods of exercise. The mechanisms by which skeletal muscle ...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/s0047-6374(01)00368-2

    authors: McArdle A,Vasilaki A,Jackson M

    更新日期:2002-02-01 00:00:00

  • Altered function of neuronal L-type calcium channels in ageing and neuroinflammation: Implications in age-related synaptic dysfunction and cognitive decline.

    abstract::The rapid developments in science have led to an increase in human life expectancy and thus, ageing and age-related disorders/diseases have become one of the greatest concerns in the 21st century. Cognitive abilities tend to decline as we get older. This age-related cognitive decline is mainly attributed to aberrant c...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2018.01.001

    authors: Navakkode S,Liu C,Soong TW

    更新日期:2018-03-01 00:00:00

  • Aging: central role for autophagy and the lysosomal degradative system.

    abstract::The lysosomal network is the major intracellular proteolytic system accounting for more than 98% of long-lived bulk protein degradation and recycling particularly in tissues such as liver and muscles. Lysosomes are the final destination of intracellular damaged structures, identified and sequestered by the processes o...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2009.05.001

    authors: Rajawat YS,Hilioti Z,Bossis I

    更新日期:2009-07-01 00:00:00

  • Physical activity and exercise in the context of SARS-Cov-2: A perspective from geroscience field.

    abstract::The recent pandemics of the SARS-Cov-2 has pushed physical activity (PA) and exercise at the forefront of the discussion, since PA is associated with a reduced risk of developing all the chronic diseases strongly associated with severe cases of SARS-Cov-2 and exercise is considered a complimentary therapeutics for the...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2021.101258

    authors: de Souto Barreto P,Vellas B,Rolland Y

    更新日期:2021-01-12 00:00:00

  • The preventive strategy for pandemics in the elderly is to collect in advance samples & data to counteract chronic inflammation (inflammaging).

    abstract::Fighting the current COVID-19 pandemic, we must not forget to prepare for the next. Since elderly and frail people are at high risk, we wish to predict their vulnerability, and intervene if possible. For example, it would take little effort to take additional swabs or dried blood spots. Such minimally-invasive samplin...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2020.101091

    authors: Fuellen G,Liesenfeld O,Kowald A,Barrantes I,Bastian M,Simm A,Jansen L,Tietz-Latza A,Quandt D,Franceschi C,Walter M

    更新日期:2020-09-01 00:00:00

  • Effect of nutritional supplementations on physical performance and muscle strength parameters in older people: A systematic review and meta-analysis.

    abstract::Malnutrition plays a role in the development of poor physical performance, frailty and sarcopenia. The use of nutritional supplementations for improving physical performance and muscle strength parameters in older people is unclear. We therefore aimed to summarize the effect of nutritional supplementations compared to...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.arr.2019.02.005

    authors: Veronese N,Stubbs B,Punzi L,Soysal P,Incalzi RA,Saller A,Maggi S

    更新日期:2019-05-01 00:00:00

  • Neurohypophyseal peptides in aging and Alzheimer's disease.

    abstract::The neurohypophyseal hormones arginine-vasopressin (AVP) and oxytocin (OT) are produced in the neurons of the hypothalamic supraoptic (SON) and paraventricular (PVN) nucleus and in the much smaller cells of the suprachiasmatic (SCN) nucleus. The SON is the main source of plasma AVP. Part of the AVP and OT neurons of t...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/s1568-1637(02)00013-2

    authors: Ishunina TA,Swaab DF

    更新日期:2002-06-01 00:00:00

  • Designing neuroreparative strategies using aged regenerating animal models.

    abstract::In our ever-aging world population, the risk of age-related neuropathies has been increasing, representing both a social and economic burden to society. Since the ability to regenerate in the adult mammalian central nervous system is very limited, brain trauma and neurodegeneration are often permanent. As a consequenc...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2020.101086

    authors: Vanhunsel S,Beckers A,Moons L

    更新日期:2020-09-01 00:00:00

  • Targeting the TLR4 signaling pathway by polyphenols: A novel therapeutic strategy for neuroinflammation.

    abstract::A wide array of cell signaling mediators and their interactions play vital roles in neuroinflammation associated with ischemia, brain trauma, developmental disorders and age-related neurodegeneration. Along with neurons, microglia and astrocytes are also affected by the inflammatory cascade by releasing pro-inflammato...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2017.02.004

    authors: Rahimifard M,Maqbool F,Moeini-Nodeh S,Niaz K,Abdollahi M,Braidy N,Nabavi SM,Nabavi SF

    更新日期:2017-07-01 00:00:00

  • Lipotoxicity, overnutrition and energy metabolism in aging.

    abstract::The safest place to store lipids is the white adipose tissue, but its storage capacity may become saturated resulting in excess of fat "overspilled" to non-adipose tissues. This overspill of fat occurs in apparently opposite pathological states such as lipodistrophy or obesity. When the excess of energy is redirected ...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2006.03.004

    authors: Slawik M,Vidal-Puig AJ

    更新日期:2006-05-01 00:00:00

  • Role of the AMPK pathway in promoting autophagic flux via modulating mitochondrial dynamics in neurodegenerative diseases: Insight into prion diseases.

    abstract::Neurons are highly energy demanding cells dependent on the mitochondrial oxidative phosphorylation system. Mitochondria generate energy via respiratory complexes that constitute the electron transport chain. Adenosine triphosphate depletion or glucose starvation act as a trigger for the activation of adenosine monopho...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2017.09.004

    authors: Shah SZA,Zhao D,Hussain T,Yang L

    更新日期:2017-11-01 00:00:00

  • LncRNA: Shedding light on mechanisms and opportunities in fibrosis and aging.

    abstract::Fibrosis is universally observed in multiple aging-related diseases and progressions and is characterized by excess accumulation of the extracellular matrix. Fibrosis occurs in various human organs and eventually results in organ failure. Noncoding RNAs (ncRNAs) have emerged as essential regulators of cellular signali...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2019.04.001

    authors: Yang Z,Jiang S,Shang J,Jiang Y,Dai Y,Xu B,Yu Y,Liang Z,Yang Y

    更新日期:2019-07-01 00:00:00

  • Selective neuronal vulnerability in Alzheimer's disease.

    abstract::Alzheimer's disease (AD) is defined by a deficiency in specific behavioural and/or cognitive domains, pointing to selective vulnerabilities of specific neurons from different brain regions. These vulnerabilities can be compared across neuron subgroups to identify the most vulnerable neuronal types, regions, and time p...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2020.101114

    authors: Wang ZT,Zhang C,Wang YJ,Dong Q,Tan L,Yu JT

    更新日期:2020-09-01 00:00:00

  • Lysines, Achilles' heel in alpha-synuclein conversion to a deadly neuronal endotoxin.

    abstract::Alpha-synuclein aggregation is associated with Parkinson's disease and other neurodegenerative disorders termed synucleinopathies. The sequence of alpha-synuclein has a remarkable amount of lysines, which may be a target for modifications by several aldehydes found at increased concentration in parkinsonian brains. Th...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2015.12.002

    authors: Plotegher N,Bubacco L

    更新日期:2016-03-01 00:00:00

  • Bioenergetics of aging and calorie restriction.

    abstract::Aging is a physiological process that involves a multi-factorial set of deleterious changes. These alterations are caused by an exponential increase in damage to macromolecules. This process is likely due to the cumulative effects of oxidative stress over time. One area of ongoing research in gerontology has focused o...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2006.03.006

    authors: Hunt ND,Hyun DH,Allard JS,Minor RK,Mattson MP,Ingram DK,de Cabo R

    更新日期:2006-05-01 00:00:00

  • Aberrant spontaneous low-frequency brain activity in amnestic mild cognitive impairment: A meta-analysis of resting-state fMRI studies.

    abstract::Recent resting-state functional magnetic resonance imaging (rs-fMRI) studies have provided strong evidence of abnormal spontaneous brain activity in amnestic mild cognitive impairment (aMCI). However, the conclusions have been inconsistent. A meta-analysis of whole-brain rs-fMRI studies that measured differences in th...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.arr.2016.12.001

    authors: Pan P,Zhu L,Yu T,Shi H,Zhang B,Qin R,Zhu X,Qian L,Zhao H,Zhou H,Xu Y

    更新日期:2017-05-01 00:00:00

  • The role of Nrf2 in neural stem/progenitors cells: From maintaining stemness and self-renewal to promoting differentiation capability and facilitating therapeutic application in neurodegenerative disease.

    abstract::Neurodegenerative diseases (NDs) cause progressive loss of neurons in nervous system. NDs are categorized as acute NDs such as stroke and head injury, besides chronic NDs including Alzheimer's, Parkinson's, Huntington's diseases, Friedreich's Ataxia, Multiple Sclerosis. The exact etiology of NDs is not understood but ...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2020.101211

    authors: Kahroba H,Ramezani B,Maadi H,Sadeghi MR,Jaberie H,Ramezani F

    更新日期:2021-01-01 00:00:00

  • The role of polyphenols in the modulation of sirtuins and other pathways involved in Alzheimer's disease.

    abstract::Alzheimer's disease (AD) is characterised by extracellular amyloid deposits, neurofibrillary tangles, synaptic loss, inflammation and extensive oxidative stress. Polyphenols, which include resveratrol, epigallocatechin gallate and curcumin, have gained considerable interest for their ability to reduce these hallmarks ...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2013.06.003

    authors: Jayasena T,Poljak A,Smythe G,Braidy N,Münch G,Sachdev P

    更新日期:2013-09-01 00:00:00

  • Vascular aging: Molecular mechanisms and potential treatments for vascular rejuvenation.

    abstract::Aging is the main risk factor contributing to vascular dysfunction and the progression of vascular diseases. In this review, we discuss the causes and mechanisms of vascular aging at the tissue and cellular level. We focus on Endothelial Cell (EC) and Smooth Muscle Cell (SMC) aging due to their critical role in mediat...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2017.05.006

    authors: Mistriotis P,Andreadis ST

    更新日期:2017-08-01 00:00:00

  • Does cellular iron dysregulation play a causative role in Parkinson's disease?

    abstract::Selective dopaminergic cell loss in Parkinson's disease is correlated with increased levels of cellular iron. It is still hotly debated as to whether the increase in iron is an upstream event which acts to promote neurodegeneration via formation of oxidative stress or whether iron accumulates as a by-product of the ne...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2004.01.003

    authors: Kaur D,Andersen J

    更新日期:2004-07-01 00:00:00

  • Added value of elder abuse definitions: a review.

    abstract::Elder abuse has devastating consequences for older persons such as a poor quality of life, psychological distress, and loss of property and security. It is also associated with increased mortality and morbidity. Elder abuse is a problem that manifests itself in both rich and poor countries and at all levels of society...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.arr.2012.04.001

    authors: Mysyuk Y,Westendorp RG,Lindenberg J

    更新日期:2013-01-01 00:00:00

  • Synthesis and metabolism of methylglyoxal, S-D-lactoylglutathione and D-lactate in cancer and Alzheimer's disease. Exploring the crossroad of eternal youth and premature aging.

    abstract::Both cancer and Alzheimer's disease (AD) are emerging as metabolic diseases in which aberrant/dysregulated glucose metabolism and bioenergetics occur, and play a key role in disease progression. Interestingly, an enhancement of glucose uptake, glycolysis and pentose phosphate pathway occurs in both cancer cells and am...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2019.100915

    authors: de Bari L,Atlante A,Armeni T,Kalapos MP

    更新日期:2019-08-01 00:00:00

  • Autophagy in bone: Self-eating to stay in balance.

    abstract::Autophagy, a major catabolic pathway responsible of the elimination of damaged proteins and organelles, is now recognized as an anti-aging process. In addition to its basal role in cell homeostasis, autophagy is also a stress-responsive mechanism for survival purposes. Here, we review recent literature to highlight th...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2015.08.004

    authors: Pierrefite-Carle V,Santucci-Darmanin S,Breuil V,Camuzard O,Carle GF

    更新日期:2015-11-01 00:00:00

  • Tau protein phosphatases in Alzheimer's disease: the leading role of PP2A.

    abstract::Tau phosphorylation is regulated by a balance between tau kinase and phosphatase activities. Disruption of this equilibrium was suggested to be at the origin of abnormal tau phosphorylation and thereby that might contributes to tau aggregation. Thus, understanding the regulation modes of tau dephosphorylation is of hi...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2012.06.008

    authors: Martin L,Latypova X,Wilson CM,Magnaudeix A,Perrin ML,Terro F

    更新日期:2013-01-01 00:00:00

  • Sunlight and health: shifting the focus from vitamin D3 to photobiomodulation by red and near-infrared light.

    abstract::Both sun exposure and serum vitamin D levels have been associated with lower risks of all-cause mortality and chronic age-related diseases, e.g., cancer, diabetes and cardiovascular disease, in epidemiological studies. These associations have mainly been ascribed to beneficial effects of vitamin D. However, a vast bod...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2020.101089

    authors: Heiskanen V,Pfiffner M,Partonen T

    更新日期:2020-08-01 00:00:00

  • Aging in COVID-19: Vulnerability, immunity and intervention.

    abstract::The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic was first reported in Wuhan, China in December 2019, moved across the globe at an unprecedented speed, and is having a profound and yet still unfolding health and socioeconomic impacts. SARS-CoV-2, a β-coronavirus, is a highly contagious respira...

    journal_title:Ageing research reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.arr.2020.101205

    authors: Chen Y,Klein SL,Garibaldi BT,Li H,Wu C,Osevala NM,Li T,Margolick JB,Pawelec G,Leng SX

    更新日期:2021-01-01 00:00:00