Abstract:
:This is the first meta-analysis focusing on elderly patients with mobility problems, physical disability and/or multi-morbidity. The aim of this study is to assess the effect of physical exercise therapy on mobility, physical functioning, physical activity and quality of life. A broad systematic literature search was performed in the databases PubMed, CINAHL, Embase, PEDro and The Cochrane Library. Relevant study characteristics were reviewed and meta-analyses using standardized mean differences (SMDs) were performed. The results show that physical exercise therapy has a positive effect on mobility (SMD final value: 0.18; 95% CI: 0.05, 0.30; SMD change value: 0.82; 95% CI: 0.54, 1.10) and physical functioning (SMD final value: 0.27; 95% CI: 0.08, 0.46; SMD change value: 2.93; 95% CI: 2.50, 3.36). High-intensity exercise interventions seem to be somewhat more effective in improving physical functioning than low-intensity exercise interventions (SMD final value: 0.22; 95% CI: -0.17, 0.62; SMD change value: 0.38; 95% CI: -0.48, 1.25). These positive effects are of great value for older adults who are already physically impaired. The effect on physical activity and quality of life was not evident and no definite conclusions on the most effective type of physical exercise therapy intervention can be drawn.
journal_name
Ageing Res Revjournal_title
Ageing research reviewsauthors
de Vries NM,van Ravensberg CD,Hobbelen JS,Olde Rikkert MG,Staal JB,Nijhuis-van der Sanden MWdoi
10.1016/j.arr.2011.11.002subject
Has Abstractpub_date
2012-01-01 00:00:00pages
136-49issue
1eissn
1568-1637issn
1872-9649pii
S1568-1637(11)00069-9journal_volume
11pub_type
杂志文章,meta分析,评审abstract::Aging effects have often been reported for spatial navigation performance. Moreover, navigation performance is thought to be an early marker of pathological aging. Yet, the cognitive complexity of navigation and large individual variation in healthy population make it difficult to pinpoint the precise aging mechanisms...
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journal_title:Ageing research reviews
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journal_title:Ageing research reviews
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journal_title:Ageing research reviews
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journal_title:Ageing research reviews
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journal_title:Ageing research reviews
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journal_title:Ageing research reviews
pub_type: 杂志文章,评审
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journal_title:Ageing research reviews
pub_type: 杂志文章,评审
doi:10.1016/j.arr.2012.01.003
更新日期:2012-09-01 00:00:00
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journal_title:Ageing research reviews
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doi:10.1016/j.arr.2015.07.006
更新日期:2015-11-01 00:00:00
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doi:10.1016/j.arr.2020.101124
更新日期:2020-09-01 00:00:00
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journal_title:Ageing research reviews
pub_type: 杂志文章,评审
doi:10.1016/j.arr.2011.12.004
更新日期:2012-04-01 00:00:00
abstract::The rapid developments in science have led to an increase in human life expectancy and thus, ageing and age-related disorders/diseases have become one of the greatest concerns in the 21st century. Cognitive abilities tend to decline as we get older. This age-related cognitive decline is mainly attributed to aberrant c...
journal_title:Ageing research reviews
pub_type: 杂志文章,评审
doi:10.1016/j.arr.2018.01.001
更新日期:2018-03-01 00:00:00
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journal_title:Ageing research reviews
pub_type: 杂志文章,评审
doi:10.1016/j.arr.2009.09.005
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journal_title:Ageing research reviews
pub_type: 杂志文章
doi:10.1016/j.arr.2010.05.002
更新日期:2010-10-01 00:00:00
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journal_title:Ageing research reviews
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doi:10.1016/j.arr.2010.08.006
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pub_type: 杂志文章,评审
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journal_title:Ageing research reviews
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journal_title:Ageing research reviews
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journal_title:Ageing research reviews
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journal_title:Ageing research reviews
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doi:10.1016/j.arr.2017.05.005
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abstract::Within the last years, a rapidly growing number of polyphenolic compounds with neuroprotective effects have been described. Many efforts have been made to explore the mechanisms behind the neuroprotective action of polyphenols. However, many pathways and mechanisms considered for mediating these effects are rather gen...
journal_title:Ageing research reviews
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更新日期:2012-04-01 00:00:00
abstract::Fibrosis is the final hallmark of pathological remodeling, which is a major contributor to the pathogenesis of various chronic diseases and aging-related organ failure to fully control chronic wound-healing and restoring tissue function. The process of fibrosis is involved in the pathogenesis of the kidney, lung, live...
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doi:10.1016/j.arr.2020.101063
更新日期:2020-07-01 00:00:00