Crystallization at the polymer/calcium-phosphate interface in a sterilized injectable bone substitute IBS.

abstract：:The aim of this study was to characterize the relation of dimensional changes of dental ceramic materials as function of temperature. The thermal dimensional behavior of one glass ceramic core, four commercially available veneering porcelains and two experimental veneering porcelain materials was determined on cooling...

journal_title：Biomaterials

authors： Isgrò G,Kleverlaan CJ,Wang H,Feilzer AJ

更新日期：2004-05-01 00:00:00

abstract：:Hydroxylated and methylated surfaces were prepared by the self-assembled monolayer technique (SAM) of alkane thiols on gold. The surfaces were used to evaluate the influence of implant surface chemistry on protein deposition and inflammatory cell response. Implants were inserted subcutaneously in the rat for 3 and 24 ...

journal_title：Biomaterials

authors： Källtorp M,Oblogina S,Jacobsson S,Karlsson A,Tengvall P,Thomsen P

更新日期：1999-11-01 00:00:00

abstract：:The aim of this study was to investigate the effects of alginate and agarose on the response of bone marrow stromal cells (BMSCs) to chondrogenic stimuli. Rat BMSCs were expanded in monolayer culture with or without FGF-2 supplementation. Cells were then seeded in 2% alginate and agarose gels and cultured in media wit...

journal_title：Biomaterials

authors： Coleman RM,Case ND,Guldberg RE

更新日期：2007-04-01 00:00:00

abstract：:The aim of this in vitro study was to evaluate the antimicrobial activity, the substantivity, and surface effects of the inclusion compound tetracycline: beta-cyclodextrin on bovine roots. The antimicrobial activity was assessed by dentine slabs which had been immersed in the inclusion complex in concentrations 8.0%, ...

journal_title：Biomaterials

authors： Pataro AL,Franco CF,Santos VR,Cortés ME,Sinisterra RD

更新日期：2003-03-01 00:00:00

abstract：:Enterococcus faecalis is an opportunistic pathogen, which today represents one of the leading aetiologic agents of nosocomial infections and, increasingly, of implant infections. Here, in a collection of 43 E. faecalis isolated from implant orthopaedic infections, virulence-related phenotypes (biofilm and gelatinase p...

journal_title：Biomaterials

authors： Arciola CR,Baldassarri L,Campoccia D,Creti R,Pirini V,Huebner J,Montanaro L

更新日期：2008-02-01 00:00:00

abstract：:Ferroptosis, a newfound non-apoptotic cell death pathway, results from the accumulation of iron-dependent lipid peroxide (LPO). Recently, emerging iron-based nanomaterials have been extensively developed to induce Fenton reaction-dependent ferroptosis for cancer therapy. However, insufficient amount of H2O2 and limite...

journal_title：Biomaterials

authors： He YJ,Liu XY,Xing L,Wan X,Chang X,Jiang HL

更新日期：2020-05-01 00:00:00

abstract：:Retinal pigment epithelial (RPE) cellular morphology and function are vital to the health of the retina. In age-related macular degeneration, RPE dysfunction and changes in Bruch's membrane occur. Thus, a potential cure is a dual-layer biomimetic transplant consisting of a layer of healthy RPE cells cultured on a supp...

journal_title：Biomaterials

authors： Lee CJ,Fishman HA,Bent SF

更新日期：2007-04-01 00:00:00

abstract：:Umbilical cord mesenchymal stem cells (UCMSCs) have shown great potentials in regenerative medicine for their extensive sources, multilineage differentiation potential, low immunogenicity and self-renewal ability. However, the clinical application of UCMSCs still confronts many challenges including the requirement of ...

journal_title：Biomaterials

authors： Qiao Y,Xu Z,Yu Y,Hou S,Geng J,Xiao T,Liang Y,Dong Q,Mei Y,Wang B,Qiao H,Dai J,Suo G

更新日期：2020-01-01 00:00:00

abstract：:The stabilities of two types of polymerically stabilized liposomes consisting of PEG-grafted (DSPC:CHOL:DSPE-PEG1900, 5:4:1) and physically adsorbed carboxymethylchitin (CMC) and carboxymethyl/glycolchitin (CO) are compared. The polyelectrolyte is adsorbed on positive (DSPC:CHOL:DMTAP, 5:4:1) and neutral (DSPC:CHOL, 1...

journal_title：Biomaterials

authors： Mobed M,Chang TM

更新日期：1998-07-01 00:00:00

abstract：:Synthetic hydroxyapatite particles of two median sizes and different morphologies have been used to manufacture hydroxyapatite reinforced high density polyethylene composites (HAPEX) for medical applications. The effects of hydroxyapatite particle size on properties of the resultant composites were investigated using ...

journal_title：Biomaterials

authors： Wang M,Joseph R,Bonfield W

更新日期：1998-12-01 00:00:00

abstract：:The ability to precisely pattern embryonic stem (ES) cells in vitro into predefined arrays/geometries may allow for the recreation of a stem cell niche for better understanding of how cellular microenvironmental factors govern stem cell maintenance and differentiation. In this study, a new gelatin-based laser direct-w...

journal_title：Biomaterials

authors： Raof NA,Schiele NR,Xie Y,Chrisey DB,Corr DT

更新日期：2011-03-01 00:00:00

abstract：:In vitro solubility tests of hydroxyapatite, tetracalcium phosphate or tricalcium phosphate particles were performed in lactate, citrate, Gomoris or Michaelis buffer with pH 6.2 or 7.2 and in aqua destillata. The results showed that in general the solubility decreased in the order tetracalcium phosphate greater than t...

journal_title：Biomaterials

authors： Klein CP,de Blieck-Hogervorst JM,Wolke JG,de Groot K

更新日期：1990-09-01 00:00:00

abstract：:Poly(epsilon-caprolactone) (PCL) was dissolved in four solvent systems, chloroform, tetrahydrofuran, acetone and ethyl acetate, and cast onto glass Petri dishes. The surface properties of the resulting films were investigated. The extent to which their properties were determined by the solvent used in each case was qu...

journal_title：Biomaterials

authors： Tang ZG,Black RA,Curran JM,Hunt JA,Rhodes NP,Williams DF

更新日期：2004-08-01 00:00:00

abstract：:Cationic nanoparticles are a promising class of transfection agents for oligonucleotide and gene delivery, but vary greatly in their effectiveness and cytotoxicity. Recently, we developed a new class of cationic transfection agents based on cationic shell-crosslinked knedel-like nanoparticles (cSCKs) that efficiently ...

journal_title：Biomaterials

authors： Zhang K,Fang H,Wang Z,Li Z,Taylor JS,Wooley KL

更新日期：2010-03-01 00:00:00

abstract：:Drug hepatotoxicity testing requires in vitro hepatocyte culture to maintain the long-term and stable liver specific functions. We developed a drug testing platform based on laminar-flow immediate-overlay hepatocyte sandwich perfusion culture. The immediate-overlay sandwich (collagen-coated porous polymeric membrane a...

journal_title：Biomaterials

authors： Xia L,Ng S,Han R,Tuo X,Xiao G,Leo HL,Cheng T,Yu H

更新日期：2009-10-01 00:00:00

abstract：:Peel bond strength and tensile bond strength between three polyvinylsiloxane denture soft liners and a heat-cured acrylic resin denture base were measured using two adhesive systems. The soft lining materials differed only in regard of their filler content and compliance. The values of bond strength and mode of failur...

journal_title：Biomaterials

authors： McCabe JF,Carrick TE,Kamohara H

更新日期：2002-03-01 00:00:00

abstract：:The development of highly funtional and orally available nanoparticles is the ultimate goal in nanoparticle delivery. Various functional nanoparticles have been studied to that end but there has yet to be an oral nanoparticle that can be successfully applied. Here, we describe for the first time a novel bile acid conj...

journal_title：Biomaterials

authors： Park J,Choi JU,Kim K,Byun Y

更新日期：2017-12-01 00:00:00

abstract：:This work reports the development of new non-thrombogenic polymers based on the linear polymers of polyamidoamines (PAAs), having heparin binding ability, obtained by polyaddition of secondary amines to N,N'-methylene bis-acrylamide. PAAs could not be used directly in the making of blood-contacting materials due to th...

journal_title：Biomaterials

authors： Dey RK,Ray AR

更新日期：2003-08-01 00:00:00

abstract：:One of the major limitations of studying cancer-bone metastasis has been the lack of an appropriate ex-vivo model which can be used under defined conditions that simulates closely the in vivo live bone microenvironment in response to cancer-bone interactions. We have developed and utilized a three-dimensional (3D) can...

journal_title：Biomaterials

authors： Curtin P,Youm H,Salih E

更新日期：2012-02-01 00:00:00

abstract：:The hydrolytic degradation of aliphatic polyesters derived from lactic and glycolic acids (PLA/GA polymers) has been previously shown to proceed heterogeneously in the case of large size devices, the rate of degradation being greater inside than at the surface. A qualitative model based on diffusion-reaction phenomena...

journal_title：Biomaterials

authors： Grizzi I,Garreau H,Li S,Vert M

更新日期：1995-03-01 00:00:00

abstract：:A new system of single piece electrodes was applied to in vivo and in vitro measurements of anodic polarization of several alloys used in orthopaedic implants. The tested surface was scrutinized with a stereomicroscope after each experiment. This confirmed pit formation and excluded the possibility of other sudden inc...

journal_title：Biomaterials

authors： Nakayama Y,Yamamuro T,Kotoura Y,Oka M

更新日期：1989-08-01 00:00:00

abstract：:Combined treatment using nonviral agent-mediated enzyme/prodrug therapy and immunotherapy had been proposed as a powerful alternative method of cancer therapy. The present study was aimed to evaluate the cytotoxicity in vitro and the therapeutic efficacy in vivo when the cytosine deaminase/5-fluorocytosine (CD/5-FC) a...

journal_title：Biomaterials

authors： Liang B,He ML,Chan CY,Chen YC,Li XP,Li Y,Zheng D,Lin MC,Kung HF,Shuai XT,Peng Y

更新日期：2009-08-01 00:00:00

abstract：:Adipose tissue engineering offers a promising alternative to the current breast reconstruction options. Here we investigated patient-specific breast scaffolds fabricated from poly(d,l)-lactide polymer with pore sizes>1 mm for their potential in long-term sustained regeneration of high volume adipose tissue. An optimis...

journal_title：Biomaterials

authors： Chhaya MP,Melchels FP,Holzapfel BM,Baldwin JG,Hutmacher DW

更新日期：2015-06-01 00:00:00

abstract：:Suture materials may interact with immune competent cells and thereby affect localized immunity. Macrophages are central to the inflammatory response and coordinate wound healing. They are also involved in the clearance of foreign material, bacteria and malignant cells. We studied the influence of soluble factors asso...

journal_title：Biomaterials

authors： Uff CR,Scott AD,Pockley AG,Phillips RK

更新日期：1995-03-01 00:00:00

abstract：:Eye drops producing long-acting ocular anesthesia would be desirable for corneal pain management. Here we present liposome-based formulations to achieve very long ocular anesthetic effect after a single eye drop instillation. The liposomes were functionalized with succinyl-Concanavalin A (sConA-Lip), which can bind co...

journal_title：Biomaterials

authors： Zhan C,Santamaria CM,Wang W,McAlvin JB,Kohane DS

更新日期：2018-10-01 00:00:00

abstract：:Rare-earth upconversion nanoparticles (UCNP) which can absorb low-energy photons and emit high energy photons have attracted great interest not only because of their unique application in upconversion luminescence imaging, but also because they can be used as ideal building blocks for multimodal bioimaging probes. Imp...

journal_title：Biomaterials

authors： Liu Q,Chen M,Sun Y,Chen G,Yang T,Gao Y,Zhang X,Li F

更新日期：2011-11-01 00:00:00

abstract：:A multifunctional organic-inorganic hybrid nanocapsule based on Bi2S3-embedded poly (lactic-co-glycolic acid) (PLGA) nanocapsule has been elaborately designed to combine the merits of both polymeric shell structure and Bi2S3 nanoparticles. Hydrophobic Bi2S3 nanoparticles were successfully introduced into the PLGA nano...

journal_title：Biomaterials

authors： Yao MH,Ma M,Chen Y,Jia XQ,Xu G,Xu HX,Chen HR,Wu R

更新日期：2014-09-01 00:00:00

abstract：:Adhesion of cells to surfaces is a basic and important requirement in cell culture and tissue engineering. Here, we designed artificial extracellular matrix (ECM) mimics for efficient cellular attachment, based on mussel adhesive protein (MAP) fusion with biofunctional peptides originating from ECM materials, includin...

journal_title：Biomaterials

authors： Choi BH,Choi YS,Kang DG,Kim BJ,Song YH,Cha HJ

更新日期：2010-12-01 00:00:00

abstract：:The photodynamic activity of a carrier-sensitizer system consisting of heterotopic colloidal nanoparticles (diameter 100-1000 nm) of a cationic amphiphilic cyclodextrin, heptakis(2-omega-amino-O-oligo(ethylene oxide)-6-hexylthio)-beta-CD (SC6CDNH2) encapsulating the anionic 5,10,15,20-tetrakis(4-sulfonatophenyl)-21H,2...

journal_title：Biomaterials

authors： Sortino S,Mazzaglia A,Monsù Scolaro L,Marino Merlo F,Valveri V,Sciortino MT

更新日期：2006-08-01 00:00:00

abstract：:Hydrogels produced from self-assembling peptides and peptide derivatives are being investigated as synthetic extracellular matrices for defined cell culture substrates and scaffolds for regenerative medicine. In many cases, however, they are less stiff than the tissues and extracellular matrices they are intended to m...

journal_title：Biomaterials

authors： Jung JP,Jones JL,Cronier SA,Collier JH

更新日期：2008-05-01 00:00:00