Studies of the solubility of different calcium phosphate ceramic particles in vitro.

abstract：:The effect of inclusion of an immobilization matrix and the capsule membrane permeability on the viability, metabolic activity, and proliferation of encapsulated HEK cells was investigated in vitro. In the absence of a matrix, a particular transfected HEK cell line formed a single aggregate in the core of the poly(hyd...

journal_title：Biomaterials

authors： Lahooti S,Sefton MV

更新日期：2000-05-01 00:00:00

abstract：:Microbial polyhydroxyalkanoates (PHA) including poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) were found to induce chondrogenesis of mesenchymal stem cells (MSCs) and preserve chondrocytic phenotype as well as support chondrocytes-specific extracellular matrix (ECM) secretion. In this study, mouse MSCs cultur...

journal_title：Biomaterials

authors： Yan C,Wang Y,Shen XY,Yang G,Jian J,Wang HS,Chen GQ,Wu Q

更新日期：2011-09-01 00:00:00

abstract：:In the traditional Chinese medicine, Gu-Sui-Bu [Drynaria fortunei (kunze) J. Sm] has been reported as a good enhancer for bone healing. In this experiment, we investigate the biochemical effects of this traditional Chinese medicine on the bone cells culture. Different concentrations of crude extract of Gu-Sui-Bu were ...

journal_title：Biomaterials

authors： Sun JS,Lin CY,Dong GC,Sheu SY,Lin FH,Chen LT,Wang YJ

更新日期：2002-08-01 00:00:00

abstract：:The regulation of endothelial cell (EC) and smooth muscle cell (SMC) proliferation following vascular interventions is critical to clinical efficacy. Our laboratory has developed a method of impregnating biomaterials with suspensions containing bioactive proteins resulting in the capability of differentially modulatin...

journal_title：Biomaterials

authors： Greisler HP,Gosselin C,Ren D,Kang SS,Kim DU

更新日期：1996-02-01 00:00:00

abstract：:Polyurethane microspheres having diameters in the range 150-1500 microns were prepared by condensation polymerization of toluene diisocyanate (TDI) with poly(tetramethylene glycol) (PTMG) of average mol wt 990 in an aqueous dispersion medium containing dioctyl sulphosuccinate (DOS) as the suspension stabilizer and 1,4...

journal_title：Biomaterials

authors： Thanoo BC,Sunny MC,Jayakrishnan A

更新日期：1991-07-01 00:00:00

abstract：:Retinal degeneration impairs the vision of millions in all age groups worldwide. Increasing evidence suggests that the etiology of many retinal degenerative diseases is associated with impairment in biochemical reactions involved in the visual cycle, a metabolic pathway responsible for regeneration of the visual chrom...

journal_title：Biomaterials

authors： Puntel A,Maeda A,Golczak M,Gao SQ,Yu G,Palczewski K,Lu ZR

更新日期：2015-03-01 00:00:00

abstract：:Adoptive cell transfer of targeted chimeric antigen receptor (CAR) T cells has emerged as a highly promising cancer therapy. The pharmacodynamic action or CAR T cells is closely related to their pharmacokinetic profile; because of this as well as the risk of non-specific action, it is important to monitor their biodis...

journal_title：Biomaterials

authors： Harmsen S,Medine EI,Moroz M,Nurili F,Lobo J,Dong Y,Turkekul M,Pillarsetty NVK,Ting R,Ponomarev V,Akin O,Aras O

更新日期：2020-12-23 00:00:00

abstract：:Tumor-homing cytotoxic stem cell (SC) therapy is a promising new approach for treating the incurable brain cancer glioblastoma (GBM). However, problems of retaining cytotoxic SCs within the post-surgical GBM resection cavity are likely to significantly limit the clinical utility of this strategy. Here, we describe a n...

journal_title：Biomaterials

authors： Bagó JR,Pegna GJ,Okolie O,Hingtgen SD

更新日期：2016-04-01 00:00:00

abstract：:Literature has shown that slowing down the curing rate of light-initiated resin composites by lowering the light intensity of the light source improved the integrity of the adhesive composite-cavity interface as a result of a more gradual contraction stress development. This study investigated how the curing rate coul...

journal_title：Biomaterials

authors： Venhoven BA,de Gee AJ,Davidson CL

更新日期：1996-12-01 00:00:00

abstract：:In an effort to examine liver injury, immune response, and other physiological effects in mice caused by intragastric administration of nanoparticulate anatase titanium dioxide (5nm), we assessed T lymphocytes, B lymphocyte and NK lymphocyte counts, hematological indices, biochemical parameters of liver functions, and...

journal_title：Biomaterials

authors： Duan Y,Liu J,Ma L,Li N,Liu H,Wang J,Zheng L,Liu C,Wang X,Zhao X,Yan J,Wang S,Wang H,Zhang X,Hong F

更新日期：2010-02-01 00:00:00

abstract：:In order to develop a more effective self-etching primer, with a longer lasting shelf life, we designed a self-etching primer comprised of methacrylamide, N-methacryloyl glycine, NMGly. In this study, the hydrolytic stability of the amide portion in the NMGly was examined. The difference in the hydrolytic stability be...

journal_title：Biomaterials

authors： Nishiyama N,Suzuki K,Yoshida H,Teshima H,Nemoto K

更新日期：2004-03-01 00:00:00

abstract：:We report here the development of a chitosan/beta-glycerophosphate(Ch/beta-GP) thermo-sensitive gel to deliver ellagic acid (EA) for cancer treatment. The properties of the Ch/beta-GP gels were characterized regarding chemical structure, surface morphology, and viscoelasticity. In vitro EA release rate from the EA loa...

journal_title：Biomaterials

authors： Kim S,Nishimoto SK,Bumgardner JD,Haggard WO,Gaber MW,Yang Y

更新日期：2010-05-01 00:00:00

abstract：:In this work, the in vitro interaction of cerebellar granule neurons prepared from 7-day-old Wistar rats and poly ethylene-co-vinyl alcohol (EVAL) membranes was investigated. Cells were cultured in smooth and particulate EVAL membranes for up to 7 days. Particulate membranes were prepared by using 1-octanol to precipi...

journal_title：Biomaterials

authors： Young TH,Lin CW,Cheng LP,Hsieh CC

更新日期：2001-07-01 00:00:00

abstract：:One of the major obstacles in drug discovery is the lack of in vitro three-dimensional (3D) models that can capture more complex features of a disease.Here we established a in vitro physiological model of the metabolic syndrome (MS) using cell-assembly technique (CAT), which can assemble cells into designated places t...

journal_title：Biomaterials

authors： Xu M,Wang X,Yan Y,Yao R,Ge Y

更新日期：2010-05-01 00:00:00

abstract：:Four commercial hydroxyapatites (both natural and synthetic) were tested to assess transformations of the chemical and crystalline structure following variation of temperature from 20 to 1600 degrees C. The thermal behaviour of hydroxyapatite is relevant for biomedical applications such as plasma spraying of metallic ...

journal_title：Biomaterials

authors： Locardi B,Pazzaglia UE,Gabbi C,Profilo B

更新日期：1993-05-01 00:00:00

abstract：:Scanning electron microscopy has been used to study the interface between implants of pure metals and the muscular tissue of rats. Several problems arise in the interpretation of the observations made, due to the potential for disruption to the tissue and the exacerbation of any corrosion that may have occurred in viv...

journal_title：Biomaterials

authors： McNamara A,Williams DF

更新日期：1982-07-01 00:00:00

abstract：:A study on the evolution with age of the mineral composition of bones was performed on samples belonging to human and other common mammalian species (cattle, sheep, dog). The study was carried out on the ashes obtained by calcination of the bone samples (1 h at 900 degrees C). The calcined powders were carefully exami...

journal_title：Biomaterials

authors： Ravaglioli A,Krajewski A,Celotti GC,Piancastelli A,Bacchini B,Montanari L,Zama G,Piombi L

更新日期：1996-03-01 00:00:00

abstract：:Effect of poly(epsilon-caprolactone) (PCL) content on the bioactivity and mechanical properties of PCL/silica hybrid was investigated. The PCL/silica hybrids with different PCL contents were prepared through co-condensation reaction with triethoxysilane end capped PCL and tetraethyl orthosilicate. The higher the PCL c...

journal_title：Biomaterials

authors： Rhee SH

更新日期：2004-03-01 00:00:00

abstract：:Engineered nanomaterials are known to exhibit diverse and sometimes unexpected biological effects. Fullerene nanoparticles have been reported to specifically bind to and elicit persistent activation of hippocampal Ca(2+)/calmodulin-dependent protein kinase II (CaMKII), a multimeric intracellular serine/threonine kinas...

journal_title：Biomaterials

authors： Chen L,Miao Y,Chen L,Xu J,Wang X,Zhao H,Shen Y,Hu Y,Bian Y,Shen Y,Chen J,Zha Y,Wen LP,Wang M

更新日期：2014-11-01 00:00:00

abstract：:As radio- and chemotherapy-based cancer treatments affect both tumors and healthy tissue, cancer immunotherapy attempts to specifically enhance the natural immune response to tumor cells. In mouse models of cancer, we tested uniform dimercaptosuccinic acid (DMSA)-coated monodisperse magnetic nanoparticles as a deliver...

journal_title：Biomaterials

authors： Mejías R,Pérez-Yagüe S,Gutiérrez L,Cabrera LI,Spada R,Acedo P,Serna CJ,Lázaro FJ,Villanueva A,Morales Mdel P,Barber DF

更新日期：2011-04-01 00:00:00

abstract：:Titanium surfaces with micro-nano hybrid topography (nanoscale nodules in microscale pits) have been recently demonstrated to show higher biological capability than those with microtopography alone. On the other hand, UV treatment of titanium surfaces, which is called UV photofunctionalization, has recently been intro...

journal_title：Biomaterials

authors： Tsukimura N,Yamada M,Iwasa F,Minamikawa H,Att W,Ueno T,Saruwatari L,Aita H,Chiou WA,Ogawa T

更新日期：2011-07-01 00:00:00

abstract：:We have developed an ion-sensing nanoparticle that is comprised of a superparamagnetic iron oxide (SPIO) core encapsulated with a porous silica shell. The latter can be readily anchored with ligands capable of coordinating with positron-emitting metal. Evidently, this nanoparticle has a great potential for use in cell...

journal_title：Biomaterials

authors： Patel D,Kell A,Simard B,Deng J,Xiang B,Lin HY,Gruwel M,Tian G

更新日期：2010-04-01 00:00:00

abstract：:Implant-associated infections represent a significant health problem and financial burden on healthcare systems. Current strategies for the treatment or prevention of such infections are still inadequate and new strategies are needed in this era of antibiotic resistance. Melimine, a synthetic antimicrobial peptide wit...

journal_title：Biomaterials

authors： Chen R,Willcox MD,Ho KK,Smyth D,Kumar N

更新日期：2016-04-01 00:00:00

abstract：:Although PEGylated liposomes (PEG-LS) have been intensively studied as drug-delivery vehicles, the rigidity and the hydrophilic PEG corona of liposomal membranes often limits cellular uptake, resulting in insufficient drug delivery to target cells. Thus, it is necessary to develop a new type of lipid-based self-assemb...

journal_title：Biomaterials

authors： Saw PE,Yu M,Choi M,Lee E,Jon S,Farokhzad OC

更新日期：2017-04-01 00:00:00

abstract：:To evaluate the biocompatibility of chemically and structurally modified polyurethane elastomers for use as blood vessel replacements, small squares of vascular prostheses were cultured in direct contact with endothelium from chick embryo aorta using an organotypic culture assay. The polyurethane materials tested were...

journal_title：Biomaterials

authors： Guidoin R,Sigot M,King M,Sigot-Luizard MF

更新日期：1992-01-01 00:00:00

abstract：:Reverse phase protein microarrays (RPMA) enable high throughput screening of posttranslational modifications of important signaling proteins within diseased cells. One limitation of protein-based molecular profiling is the lack of a PCR-like intrinsic amplification system for proteins. Enhancement of protein microarra...

journal_title：Biomaterials

authors： Nijdam AJ,Ming-Cheng Cheng M,Geho DH,Fedele R,Herrmann P,Killian K,Espina V,Petricoin EF 3rd,Liotta LA,Ferrari M

更新日期：2007-01-01 00:00:00

abstract：:Adhesion of cells to surfaces is a basic and important requirement in cell culture and tissue engineering. Here, we designed artificial extracellular matrix (ECM) mimics for efficient cellular attachment, based on mussel adhesive protein (MAP) fusion with biofunctional peptides originating from ECM materials, includin...

journal_title：Biomaterials

authors： Choi BH,Choi YS,Kang DG,Kim BJ,Song YH,Cha HJ

更新日期：2010-12-01 00:00:00

abstract：:Periosteal derived bovine osteoblast-like cells migrated in culture onto an ionomeric cement. Cell cultures were maintained for 4 weeks and used to study the in vitro behaviour of cells on the ionomeric bone cement (IC). The cells produced bone matrix proteins (osteocalcin, bone sialoprotein II) and were osteoblast-li...

journal_title：Biomaterials

authors： Meyer U,Szulczewski DH,Barckhaus RH,Atkinson M,Jones DB

更新日期：1993-10-01 00:00:00

abstract：:Biomaterials can potentially influence stem and progenitor cell proliferation and differentiation in both a positive and a negative way. Herein, we report on the expansion and differentiation of rat embryonic (E17) liver (RLC-18) cells on new bioactive membrane made of PEEK-WC-PU, whose surface was grafted with nitrog...

journal_title：Biomaterials

authors： Pavlica S,Piscioneri A,Peinemann F,Keller M,Milosevic J,Staeudte A,Heilmann A,Schulz-Siegmund M,Laera S,Favia P,De Bartolo L,Bader A

更新日期：2009-11-01 00:00:00

abstract：:Three-dimensional gelatin-chondroitin 6 sulphate-hyanuronic acid (gelatin-C6S-HA) biomatrices were used as the scaffold to investigate the phenotypic and molecular expression of basement membrane (BM) and extracellular matrix (ECM) proteins in vitro. The cells were cultured in three different culture conditions: kerat...

journal_title：Biomaterials

authors： Wang TW,Sun JS,Huang YC,Wu HC,Chen LT,Lin FH

更新日期：2006-10-01 00:00:00