Abstract:
:The surface ultrastructure of Kupffer cells in the rat liver has been studied by scanning electron microscopy (SEM). The results demonstrate that Kupffer cells are both significantly different and clearly distinct from endothelial cells. Kupffer cells have neither pores (and/or "sieve plates") nor fenestrations, all of which are present in endothelial cells. They possess a stellate shape, and only indirectly, with slender and irregular evaginations, contribute to the lining of the sinusoidal wall. Furthermore, the luminal surface in some areas contains a large population of short microvilli, microphicae and invaginations. These elements form a kind of microlabyrinth which may correpond to the "worm-like" structures described by transmission electron microscopy (TEM). In the present study, transition forms between endothelial and Kupffer cells were never found. On the contrary, considering the highly fenestrated nature of the endothelial cells, the Kupffer cells may, by ameboid movements, easily cross the overlapping barrier of the sinusoid and protrude into the lumen. Thus, acting as activated macrophages, the Kupffer cells might function to prevent the entrance of foreign material into the tissues of the liver through the fragile and highly fenestrated endothelium. Finally, the topographical reconstruction of the sinusoid by correlated SEM and TEM studies demonstrates the Kupffer cells, with their protruding cytoplasm and ability to extend into the lumen of the sinusoid, may actually change the caliber of the vessel, and thus function as a "sphincter" which causes a temporary arrest of the blood flow when the diameter of the sinusoidal lumen is reduced.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Motta Pdoi
10.1007/BF00223015keywords:
subject
Has Abstractpub_date
1975-12-10 00:00:00pages
371-85issue
3eissn
0302-766Xissn
1432-0878journal_volume
164pub_type
杂志文章abstract::Horse spleen ferritin, injected into the blood of the octopus, leaves the capillaries via pericyte junctions and windows. One hour after the administration, ferritin has entered the optic gland main cells; three hours later, it is accumulated in dense-bodies. The evidence for resorption supports earlier papers reporti...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00361712
更新日期:1976-08-10 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219611
更新日期:1976-06-28 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217281
更新日期:1982-01-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
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abstract::This study aimed to characterize porcine Achilles tendon (PAT) in terms of its structural components, vascularity, and resident tendon cells. We found that PAT is composed of a paratenon sheath, a core of fascicles, and an endotenon/interfascicular matrix (IFM) that encases the fascicle bundles. We analyzed each of th...
journal_title:Cell and tissue research
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journal_title:Cell and tissue research
pub_type: 杂志文章
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更新日期:1983-01-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233895
更新日期:1978-12-29 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222429
更新日期:1978-07-27 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
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更新日期:1994-07-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00251058
更新日期:1986-01-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222295
更新日期:1988-08-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218494
更新日期:1975-11-19 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-004-0952-0
更新日期:2005-01-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00224474
更新日期:1976-01-28 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00319624
更新日期:1992-08-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00224373
更新日期:1978-02-24 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
pub_type: 杂志文章,评审
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222805
更新日期:1975-12-29 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章,评审
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更新日期:2017-03-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004419900142
更新日期:2000-02-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222289
更新日期:1988-08-01 00:00:00
abstract::The electron-dense tracers ferritin, and iron-dextran, and the protein horseradish peroxidase, have been used to investigate the ultrastructural basis of permeability in the upper and lower segments of the Malpighian tubules of Glomeris marginata. All these materials were able to cross the basal lamina and enter the t...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219837
更新日期:1977-09-05 00:00:00
abstract::The evolution of aquaporin-5 (AQP5) expression during postnatal development has not been defined in the sweat gland. Previous studies have suggested that AQP isoforms in several peripheral targets are regulated by a neural mechanism. We have examined, in rat sweat glands, the expression of AQP5 during postnatal develo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0399-1
更新日期:2007-07-01 00:00:00
abstract::The otoconia of Amphibia, especially of the frog Rana esculenta, were studied by X-ray diffraction and scanning electron microscopy (SEM). The SEM studies showed that the membranous labyrinth of Amphibia contains two populations of crystals, which can easily be distinguished by their forms. The X-ray diffraction data ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222230
更新日期:1983-01-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-015-2256-y
更新日期:2016-02-01 00:00:00
abstract::The midgut cells of Tomocerus minor (Insecta, Collembola) were examined with the electron microscope and cytochemically. The midgut epithelium consists of a series of cells characterised by numerous mineral concretions scattered throughout the cytoplasm. Mitochondria are abundant; microvilli are well developed at the ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00236347
更新日期:1979-01-30 00:00:00