Methylation of inorganic and organic selenium by the bacterial thiopurine methyltransferase.

Abstract:

:Escherichia coli cells expressing the tpm gene encoding the bacterial thiopurine methyltransferase (bTPMT) are shown to methylate selenite and (methyl)selenocysteine into dimethylselenide (DMSe) and dimethyldiselenide (DMDSe). E. coli cells expressing tpm from a gene library cosmid clone (harboring a Pseudomonas syringae insert of about 20 kb) also methylated selenate into DMSe and DMDSe. bTPMT is the first methyltransferase shown to be involved in the methylation of these selenium derivatives.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Ranjard L,Prigent-Combaret C,Nazaret S,Cournoyer B

doi

10.1128/jb.184.11.3146-3149.2002

keywords:

subject

Has Abstract

pub_date

2002-06-01 00:00:00

pages

3146-9

issue

11

eissn

0021-9193

issn

1098-5530

journal_volume

184

pub_type

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