Genetic and biochemical analysis of the isoenzymes concerned in the first reaction of aromatic biosynthesis in Escherichia coli.

Abstract:

:Mutant strains of Escherichia coli K-12 were isolated possessing mutations which affected the tyrosine-inhibitable 3-deoxy-d-arabinoheptulosonic acid-7-phosphate (DAHP) synthetase, the phenylalanine-inhibitable DAHP synthetase, or the tryptophan-repressible DAHP synthetase. The mutations causing the loss of each of these activities have been mapped and are widely separated from each other on the E. coli chromosome. Chromatography on diethylaminoethyl cellulose columns allowed the recognition of four peaks of activity.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Wallace BJ,Pittard J

doi

10.1128/JB.93.1.237-244.1967

subject

Has Abstract

pub_date

1967-01-01 00:00:00

pages

237-44

issue

1

eissn

0021-9193

issn

1098-5530

journal_volume

93

pub_type

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