Myosin in developing normal and dystrophic chicken pectoralis. I. Synthesis and degradation.

Abstract:

:The synthesis and degradation of pectoralis myosin have been investigated in chickens 15-23 days after hatching. An essentially nonreutilizable tracer amino acid was used to demonstrate differences in the rates of synthesis and degradation of myosin isolated from normal and hypertrophied, cystrophic breast tissue. The analyses have shown that the dystrophic system synthesizes myosin faster than the normal system and that only myosin in dystrophic pectoralis is degraded during the experimental period. Double label experiments have indicated that the heavy chains of dystrophic myosin are destroyed at a rate greater than that characteristic of the light chains.

journal_name

J Cell Physiol

authors

Rourke AW

doi

10.1002/jcp.1040860406

keywords:

subject

Has Abstract

pub_date

1975-10-01 00:00:00

pages

343-51

issue

2 PT 2 SUPPL 1

eissn

0021-9541

issn

1097-4652

journal_volume

86

pub_type

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