Permselectivity changes in malaria (Plasmodium falciparum) infected human red blood cell membranes.

abstract：:Excess reactive oxygen species (ROS) generated in embryos during in vitro culture damage cellular macromolecules and embryo development. Glutathione (GSH) scavenges ROS and optimizes the culture system. However, how exogenous GSH influences intracellular GSH and improves the embryo developmental rate is poorly underst...

journal_title：Journal of cellular physiology

authors： Li F,Cui L,Yu D,Hao H,Liu Y,Zhao X,Pang Y,Zhu H,Du W

更新日期：2019-05-01 00:00:00

abstract：:Cardiac hypertrophy is the main cause of heart failure and sudden death in patients. But the pathogenesis is unclear. Angiotensin II may contribute to cardiac hypertrophy in response to pressure overload. In angiotensin II-treated cardiomyocytes, there is a larger cross-sectional area, more apoptosis cells, and a redu...

journal_title：Journal of cellular physiology

authors： Li R,Wang X,Wu S,Wu Y,Chen H,Xin J,Li H,Lan J,Xue K,Li X,Zhuo C,He J,Tang CS,Jiang W

更新日期：2019-08-01 00:00:00

abstract：:Invasion of tumor cells is the primary cause of therapeutic failure in the treatment of malignant chondrosarcomas. Glial cell-derived neurotrophic factor (GDNF) plays a crucial role in migration and metastasis of human cancer cells. Integrins are the major adhesive molecules in mammalian cells. Here we found that GDNF...

journal_title：Journal of cellular physiology

authors： Su CM,Lu DY,Hsu CJ,Chen HT,Huang CY,Yang WH,Su YC,Yang SN,Fong YC,Tseng WP,Tang CH

更新日期：2009-08-01 00:00:00

abstract：:We have described recently that expression of CD44 exon v10 (CD44v10) is down-regulated upon metastasis of squamous cell carcinoma, whereas it is up-regulated in skin metastases of malignant melanoma. The striking regulation of CD44v10 prompted us to generate a murine CD44v10-specific monoclonal antibody to define exp...

journal_title：Journal of cellular physiology

authors： Rösel M,Seiter S,Zöller M

更新日期：1997-06-01 00:00:00

abstract：:This review addresses peptide regions of human tumor liberated protein (TLP) complexes with antigenic activity. The review also deals with antibodies reacting with such proteins, to be used for diagnostic and clinical purposes. We identified peptide sequences of the TLP 100 kDa protein. Lung cancer cells were found po...

journal_title：Journal of cellular physiology

authors： Tarro G

更新日期：2009-10-01 00:00:00

abstract：:Cell-based cartilage resurfacing requires ex vivo expansion of autologous articular chondrocytes. Defined culture conditions minimize expansion-dependent phenotypic alterations but maintenance of the cells' differentiation potential must be carefully assessed. Transforming growth factor β-1 (TGF β-1) positively regula...

journal_title：Journal of cellular physiology

authors： Narcisi R,Quarto R,Ulivi V,Muraglia A,Molfetta L,Giannoni P

更新日期：2012-09-01 00:00:00

abstract：:Gastric cancer prognoses are persistently poor due to cancer's penchant to metastasize. As a crucial regulator of signal transducer and activator of transcription (STAT3) signaling, sirtuin 1's (SIRT1) function in gastric cancer has not been well understood. Here, we report upregulated expression of SIRT1 in tissues i...

journal_title：Journal of cellular physiology

authors： Zhang S,Yang Y,Huang S,Deng C,Zhou S,Yang J,Cao Y,Xu L,Yuan Y,Yang J,Chen G,Zhou L,Lv Y,Wang L,Zou X

更新日期：2019-09-01 00:00:00

abstract：:As a natural metabolite of limonoids from Dictamnus dasycarpus, fraxinellone has been reported to be neuroprotective and anti-inflammatory. However, its influence on cellular metabolism remains largely unknown. In the present study, we investigated the effect of fraxinellone on cellular senescence-induced by oxidative...

journal_title：Journal of cellular physiology

authors： Han X,Chen H,Zhou J,Tai H,Gong H,Wang X,Huang N,Qin J,Fang T,Wang F,Xiao H

更新日期：2018-05-01 00:00:00

abstract：:Acute respiratory distress syndrome (ARDS), characterized by acute hypoxic respiratory dysfunction or failure, is a manifestation of multiple organ failure in the lung, and the most common risk factor is sepsis. We previously showed that blocking α2 -adrenoceptor (α2 -AR) could attenuate lung injury induced by endotox...

journal_title：Journal of cellular physiology

authors： Cong Z,Li D,Tao Y,Lv X,Zhu X

更新日期：2020-10-01 00:00:00

abstract：:A protein carboxyl methyltransferase (PCMT), which specifically modifies atypical protein L-isoaspartyl and D-aspartyl residues, is widely distributed in eucaryotic cells, but the factors that regulate its activity in vivo have not been identified. It has been proposed that the PCMT initiates the repair of structurall...

journal_title：Journal of cellular physiology

authors： Ladino CA,O'Connor CM

更新日期：1992-11-01 00:00:00

abstract：:Despite the advantages of transplantation of umbilical cord blood's (UCB's) hematopoietic stem cells (uHSCs) for hematologic malignancy treatment, there are two major challenges in using them: (a) Insufficient amount of uHSCs in a UCB unit; (b) a defect in uHSCs homing to bone marrow (BM) due to loose binding of their...

journal_title：Journal of cellular physiology

authors： Islami M,Payandeh Z,Dalir Abdolahinia E,Saburi E,Soleimanifar F,Kehtari M,Mortazavi Y,Nadri S,Darvish M

更新日期：2019-12-01 00:00:00

abstract：:The human chronic myeloid leukemia cell line K562 acquires several megakaryoblastoid features when cultured in the presence of the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate (TPA). We observed strongly increased secretion of several proteins into the culture media of K562 cells within a few hours of TPA trea...

journal_title：Journal of cellular physiology

authors： Alitalo R,Andersson LC,Tapiovaara H,Sistonen L,Vaheri A,Stephens R

更新日期：1989-07-01 00:00:00

abstract：:The essential trace element zinc (Zn) is widely required in cellular functions, and abnormal Zn homeostasis causes a variety of health problems including immunodeficiency and sensory dysfunctions. Previous studies had shown that Zn availability was also important for tumor growth and progression. The aim of the presen...

journal_title：Journal of cellular physiology

authors： Yu Z,Yu Z,Chen Z,Yang L,Ma M,Lu S,Wang C,Teng C,Nie Y

更新日期：2019-11-01 00:00:00

abstract：:The protein tyrosine kinase pp125FAK (focal adhesion kinase, or FAK) is expressed by a variety of cell types and has been implicated in integrin-mediated signaling events. We explored the potential functions of FAK by expressing it de novo in a cell type lacking FAK. We showed previously that cultured human macrophage...

journal_title：Journal of cellular physiology

authors： De Nichilo MO,Katz BZ,O'Connell B,Yamada KM

更新日期：1999-02-01 00:00:00

abstract：:The presence and origin of mast-cell precursors fixed in the skin tissue of mice were investigated. Giant granules of beige (C57BL/6-bh'/bg', Chediak-Higashi syndrome) mice were used to distinguish different populations of mast cells. Pieces of the skin were grafted from the intact WBB6F1 (WB X C57BL/6)F1-+/+ mice int...

journal_title：Journal of cellular physiology

authors： Matsuda H,Kitamura Y,Sonoda T,Imori T

更新日期：1981-09-01 00:00:00

abstract：:The transforming growth factor-beta (TGF-beta) superfamily includes more than 30 members which have a broad array of biological activities. TGF-beta superfamily ligands bind to type II and type I serine/threonine kinase receptors and transduce signals via Smad proteins. Receptor-regulated Smads (R-Smads) can be classi...

journal_title：Journal of cellular physiology

authors： Miyazono K,Kusanagi K,Inoue H

更新日期：2001-06-01 00:00:00

abstract：:Several papers report a hypoxia-induced upregulation of the endothelial nitric oxide synthase (eNOS) mRNA expression. Since there is no known hypoxia-sensitive element binding site in the eNOS promoter, we reasoned that the effect of hypoxia could be simulated by a metabolically elicited alteration of the redox state....

journal_title：Journal of cellular physiology

authors： Hoffmann A,Gloe T,Pohl U

更新日期：2001-07-01 00:00:00

abstract：:Extracellular ATP and other nucleotides induce autocrine and/or paracrine purinergic signalling via activation of the P2 receptors on the cell surface, which represents one of the most common signalling mechanisms. Mesenchymal stem cells (MSC) are a type of multipotent adult stem cells that have many promising applica...

journal_title：Journal of cellular physiology

authors： Jiang LH,Hao Y,Mousawi F,Peng H,Yang X

更新日期：2017-02-01 00:00:00

abstract：:Toll-like receptors (TLRs) are related to foam cell formation (FCF), key event in the establishment/progression of atherosclerosis. The activation of TLR2 and TLR4 can increase FCF. The aim of this study was to evaluate the role of TLR9 in FCF. Murine macrophages were treated with CpG-ODN, TLR9 agonist, and oxidized p...

journal_title：Journal of cellular physiology

authors： Sorrentino R,Morello S,Chen S,Bonavita E,Pinto A

更新日期：2010-04-01 00:00:00

abstract：:Studies on a normal human diploid cell strain revealed that the specific activity of the cell protein, for each of the three enzymes of the Leloir pathway, changed significantly as the cells grew. The kinetics of change in specific activity varied according to the enzyme being studied, and the kinetics for each enzyme...

journal_title：Journal of cellular physiology

authors： Stern ES,Krooth RS

更新日期：1975-08-01 00:00:00

abstract：BACKGROUND:Cigarette smoke exposure, increasing Toll-like receptor 4 (TLR4) and reactive oxygen species (ROS), promotes inflammatory responses in airway epithelial cells. Chronic inflammation, microRNA (miRNA), and oxidative stress are associated with cancer development. AIMS:The present study was aimed to explore whe...

journal_title：Journal of cellular physiology

authors： Pace E,Di Vincenzo S,Di Salvo E,Genovese S,Dino P,Sangiorgi C,Ferraro M,Gangemi S

更新日期：2019-12-01 00:00:00

abstract：:Sirtuins are a family of enzymes, which govern a number of cellular processes essential for maintaining physiological balance. SIRT6, a nuclear sirtuin, is implicated in the development of metabolic disorders. The role of SIRT6 in regulation of cardiac metabolism is unexplored. Although glucose is not the primary ener...

journal_title：Journal of cellular physiology

authors： Khan D,Sarikhani M,Dasgupta S,Maniyadath B,Pandit AS,Mishra S,Ahamed F,Dubey A,Fathma N,Atreya HS,Kolthur-Seetharam U,Sundaresan NR

更新日期：2018-07-01 00:00:00

abstract：:To evaluate the regulation of endothelial cell Cu,Zn-SOD, we have exposed bovine pulmonary artery endothelial cells in culture to hyperoxia and hypoxia, second messengers or related agonists, hormones, free radical generating systems, endotoxin, and cytokines and have measured Cu,Zn-SOD protein of these cells by an EL...

journal_title：Journal of cellular physiology

authors： Kong XJ,Fanburg BL

更新日期：1992-12-01 00:00:00

abstract：:Polyploidy has been linked to tumorigenicity mainly due to the chromosomal aberrations. Elevated reactive oxygen species (ROS) generation, on the other hand, has also been associated with oncogenic transformation in most cancer cells. However, a possible link between ploidy and ROS is largely unexplored. Here we have ...

journal_title：Journal of cellular physiology

authors： Roh M,van der Meer R,Abdulkadir SA

更新日期：2012-02-01 00:00:00

abstract：:Arsenicosis induced by chronic exposure to arsenic is recognized as one of the main damaging effects on public health. Exposure to arsenic can cause hepatic fibrosis, but the molecular mechanisms by which this occurs are complex and elusive. It is not known if miRNAs are involved in arsenic-induced liver fibrosis. We ...

journal_title：Journal of cellular physiology

authors： Xue J,Xiao T,Wei S,Sun J,Zou Z,Shi M,Sun Q,Dai X,Wu L,Li J,Xia H,Tang H,Zhang A,Liu Q

更新日期：2021-01-22 00:00:00

abstract：:Biology of glomerular visceral epithelial cells ("podocytes") and their role in inflammatory process remain obscure, partly because of the lack of well-differentiated podocyte cultures. We have established a human cell line by transfecting with a replication-defective SV40 plasmid (pSVHB1), a primary culture of podocy...

journal_title：Journal of cellular physiology

authors： Ardaillou N,Lelongt B,Turner N,Piedagnel R,Baudouin B,Estrade S,Cassingena R,Ronco PM

更新日期：1992-09-01 00:00:00

abstract：:The plasma membrane of erythrocytes, as of other cells, is thought to act as the barrier responsible for maintaining intracellular gradients of most ions and small molecular species between the cell and its environment. Controlled application of the nonionic detergent Brij 58 effectively opened the erythrocyte plasma ...

journal_title：Journal of cellular physiology

authors： Kellermayer M,Ludány A,Miseta A,Kŏszegi T,Berta G,Bogner P,Hazlewood CF,Cameron IL,Wheatley DN

更新日期：1994-05-01 00:00:00

abstract：:Although osteoarthritis (OA) in the hip joint is a common and debilitating degenerative disease, the precise molecular mechanisms underlying its pathological process remains unclear. This study sets out to investigate whether β-catenin plays a critical role in hip OA pathogenesis. Here, we showed overexpressed β-caten...

journal_title：Journal of cellular physiology

authors： Xia C,Wang P,Fang L,Ge Q,Zou Z,Dong R,Zhang P,Shi Z,Xu R,Zhang L,Luo C,Ying J,Xiao L,Shen J,Chen D,Tong P,Jin H

更新日期：2019-08-01 00:00:00

abstract：:Bethanechol, a muscarinic agonist, inhibits the initial rate of amiloride-sensitive Na uptake by intact mucosa of avian small intestine as well as by isolated chicken villus enterocytes, an effect that is maximal at 90 seconds and reverses by 6 minutes. Bethanechol similarly decreases intracellular pH in isolated cell...

journal_title：Journal of cellular physiology

authors： Musch MW,Drabik-Arvans D,Rao MC,Chang EB

更新日期：1992-08-01 00:00:00

abstract：:The biological effects of the Corticotropin-releasing factor (CRF) family of neuropeptides are mediated by mobilization of [Ca(2+)]. Aim of the current work was to examine if the calcineurin/NFAT (nuclear factor of activated T-cells) signaling pathway is involved in the effect of CRF peptides in catecholamine synthesi...

journal_title：Journal of cellular physiology

authors： Dermitzaki E,Tsatsanis C,Gravanis A,Margioris AN

更新日期：2012-05-01 00:00:00