Role of protein tyrosine kinase in IL-1 beta induced activation of mitogen-activated protein kinase in fibroblast-like synoviocytes of rheumatoid arthritis.

abstract：BACKGROUND:Esophageal carcinoma is a common kind of malignant tumor and about 90% of which is esophageal squamous cell carcinoma (ESCC), and it has a high incidence in China. In recent years it has been argued that angiogenesis plays a key role in tumor growth and metastasis and it is a complex process influenced by ma...

journal_title：Chinese medical journal

authors： Chen XY,Li JS,Liang QP,He DZ,Zhao J

更新日期：2008-05-20 00:00:00

abstract：BACKGROUND:Chimerism analysis is an important tool for the surveillance of post-transplant engraftment. It offers the possibility of identifying impending graft rejection and recurrence of underlying malignant or non-malignant disease. Here we investigated the quantitative chimerism kinetics of 21 relapsed leukemia pat...

journal_title：Chinese medical journal

authors： Qin XY,Li GX,Qin YZ,Wang Y,Wang FR,Liu DH,Xu LP,Chen H,Han W,Wang JZ,Zhang XH,Li JL,Li LD,Liu KY,Huang XJ

更新日期：2012-06-01 00:00:00

abstract：Background:Type 2 diabetes (T2DM) patients are susceptible to Helicobacter pylori (HP), and it has been reported that the occurrence of proteinuria is associated with HP infection in T2DM patients; however, this view remains controversial. This meta-analysis aimed to explore the association between HP infection and the...

journal_title：Chinese medical journal

authors： Shi Y,Duan JY,Liu DW,Qiao YJ,Han QX,Pan SK,Tang L,Cai GY,Chen XM,Liu ZS,Zhu HY

更新日期：2018-11-20 00:00:00

abstract：BACKGROUND:Sericin peptide (SP) has shown a powerful anti-oxidant property in a host of studies. The present study was designed to investigate the possible protective effects of SP against alcohol-induced gastric lesions in mice and to explore the potential mechanisms. METHODS:Animals were randomly divided into 5 grou...

journal_title：Chinese medical journal

authors： Li YG,Ji DF,Lin TB,Zhong S,Hu GY,Chen S

更新日期：2008-10-20 00:00:00

abstract：BACKGROUND:Excessive expression of thymic stromal lymphopoietin (TSLP) has been demonstrated in asthmatic airway epithelia and in nasal epithelia from animal models of allergic rhinitis (AR), but the evidence of expression of TSLP in nasal epithelial cells (NECs) of patients with AR is lacking. We aimed to investigate ...

journal_title：Chinese medical journal

authors： Zhu DD,Zhu XW,Jiang XD,Dong Z

更新日期：2009-10-05 00:00:00

abstract：BACKGROUND:Intravertebral and general anesthesia (GA) are two main anesthesia approaches but both have defects. This study was aimed to evaluate the effect of subarachnoid anesthesia combined with propofol target-controlled infusion (TCI) on blood loss and transfusion for total hip arthroplasty (THA) in elderly patient...

journal_title：Chinese medical journal

authors： Xu CS,Qu XD,Qu ZJ,Wang G,Wang HJ

更新日期：2020-03-20 00:00:00

abstract：BACKGROUND:Successful antiretroviral therapy (ART) has been demonstrated to be effective in reducing the infectivity of human immunodeficiency virus (HIV). We conducted a study to predict the potential effect of ART on the spread of HIV in Chaoyang District, Beijing, China, using the Asian Epidemic Model (AEM). METHOD...

journal_title：Chinese medical journal

authors： Tao LL,Liu M,Li SM,Liu J,Jiang SL,Wang LJ,Luo FJ,Wang N

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Recently, substrate mapping (SM) has been described to facilitate catheter ablation of stable and unstable ventricular tachycardia (VT) after myocardial infarction. However, SM is time consuming with potential disadvantages of multiple ablation lines such as impairment of ventricular function or proarrhythmi...

journal_title：Chinese medical journal

authors： Li YG,Grönefeld G,Israel C,Lu SB,Wang QS,Meng S,Hohnloser SH

更新日期：2006-07-20 00:00:00

abstract：OBJECTIVE:To explore the characteristics of Helicobacter pylori (H. pylori) antigen in serum and to evaluate its clinical diagnostic value. METHODS:Enzyme-linked immunosorbant assay (ELISA) was developed to detect the soluble H. pylori antigen (S-Hp) and circulatory specific H. pylori antigen immunocomplexes (Hp-IC) i...

journal_title：Chinese medical journal

authors： Zhu Y,Lin J,Li D,Du Q,Qian K,Wu Q,Zheng S

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Since early December 2019, the 2019 novel coronavirus disease (COVID-19) has caused pneumonia epidemic in Wuhan, Hubei province of China. This study aimed to investigate the factors affecting the progression of pneumonia in COVID-19 patients. Associated results will be used to evaluate the prognosis and to f...

journal_title：Chinese medical journal

authors： Liu W,Tao ZW,Wang L,Yuan ML,Liu K,Zhou L,Wei S,Deng Y,Liu J,Liu HG,Yang M,Hu Y

更新日期：2020-05-05 00:00:00

abstract：OBJECTIVE:To investigate the correlation between glutathione S-transferase (GST) M1 and T1 genotypes and endometriosis risk (EM). METHODS:Polymerase chain reaction (PCR) technique was used to detect the presence or absence of the GSTM1 and GSTT1 genes in genomic DNA isolated from the blood samples of 68 Han Chinese wo...

journal_title：Chinese medical journal

authors： Lin J,Zhang X,Qian Y,Ye Y,Shi Y,Xu K,Xu J

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:The Xpert MTB/RIF showed high sensitivity and specificity in previous studies carried out in different epidemiological and geographical settings and patient populations in high-burden tuberculosis (TB) countries. However, there were little data obtained by validation or demonstration study of the assay in Ch...

journal_title：Chinese medical journal

authors： Hu P,Bai L,Liu F,Ou X,Zhang Z,Yi S,Chen Z,Gong D,Liu B,Guo J,Tan Y

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Distal pancreatectomy traditionally included splenectomy; the spleen, however, is an important organ in the immunologic defense of the host and is worthy of preservation. The aim of this research was to study the feasibility, safety and clinical effects of spleen and splenic vessel-preserving distal pancreat...

journal_title：Chinese medical journal

authors： Ma JP,Chen CQ,Peng L,Zhao G,Cai SR,Hu SX,He YL,Zhan WH

更新日期：2011-04-01 00:00:00

abstract：:Cogan’s syndrome (CS) is a rare inflammatory disorder characterized by interstitial keratitis and vestibuloauditory abnormalities often associated with various systemic manifestations. Involvement of cardiovascular system resembling systemic vasculitis may lead to severe complications and death. The present report des...

journal_title：Chinese medical journal

authors： Branislava I,Marijana T,Nemanja D,Dragan S,Maja Z

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To induce islet grafting tolerance by intravenous injection of anti-CD4, anti-CD8 immunotoxins and donor soluble antigen. METHODS:Fourteen days or 7 days prior to transplantation, the immunotoxin of anti-CD4, anti-CD8 200 micrograms respectively, and donor soluble antigen 500 micrograms were intravenously in...

journal_title：Chinese medical journal

authors： Lan P,Yan L,Xiao L

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:In vivo quantification of choroidal neovascularization (CNV) based on noninvasive optical coherence tomography (OCT) examination and in vitro choroidal flatmount immunohistochemistry stained of CNV currently were used to evaluate the process and severity of age-related macular degeneration (AMD) both in huma...

journal_title：Chinese medical journal

authors： Nie C,Zhang MN,Zhao HW,Olsen TD,Jackman K,Hu LN,Ma WP,Chen XF,Wang J,Zhang Y,Gao TS,Uehara H,Ambati BK,Luo L

更新日期：2015-06-05 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) is a common primary cancer frequently associated with hepatitis B virus (HBV) infection. However, whether these identified genes are particularly associated with HBV-related HCC remains unknown. The aim of this study was to investigate the differential gene expression between H...

journal_title：Chinese medical journal

authors： Huang YK,Fan XG,Qiu F,Wang ZM

更新日期：2011-07-05 00:00:00

abstract：BACKGROUND:The postremission therapies for adult patients generally contain consolidation chemotherapy, allogeneic hematopoietic stem cell transplantation and autologous hematopoietic stem cell transplantation (auto-HSCT). Because of the various results from different centers, the optimal therapy for adult acute lympho...

journal_title：Chinese medical journal

authors： Ding Z,Han MZ,Chen SL,Ma QL,Wei JL,Pang AM,Zhang XY,Liang C,Yao JF,Cao YG,Feng SZ,Jiang EL

更新日期：2015-08-05 00:00:00

abstract：OBJECTIVE:To review the advances of studies on vitamin D receptor and its role in the pathogenesis of diabetic nephropathy. DATA SOURCES:A comprehensive search of the PubMed literatures without restriction on the publication date was carried out using keywords such as vitamin D receptor and diabetic nephropathy. STUD...

journal_title：Chinese medical journal

authors： Guan X,Yang H,Zhang W,Wang H,Liao L

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The activation of extracellular signal-regulated kinase1/2 (ERK1/2) has been shown to be important signaling pathway in the ischemic preconditioning (IPC) response. Recently, some studies suggest a key role for the mitochondrial ATP-sensitive potassium channel (mKATP) as both a trigger and an end effector of...

journal_title：Chinese medical journal

authors： Gong KZ,Zhang ZG,Li AH,Huang YF,Bu P,Dong F,Liu J

更新日期：2004-03-01 00:00:00

abstract：:Immunohistochemical and ultrastructural findings in a primary intracranial endodermal sinus tumor are reported in this paper. The tumor cells exhibited AFP, CEA and anti-alpha-1-trypsin positive immunoreactivity immunocytochemically. Aggregates of electron-dense material in the extra- and intracellular spaces and amor...

journal_title：Chinese medical journal

authors： Shi QL,Jin XZ,Zhou XJ,Qian YC,Shi Q

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Aquaporin-1 (AQP1) has involved in fluid transport in diverse pulmonary edema diseases. Our study aimed to explore the dynamic changes of AQP1 in pulmonary water metabolism in rats following traumatic brain injury (TBI) and the protective effect provided by shenmai injection. METHODS:Sixty male Sprague Dawl...

journal_title：Chinese medical journal

authors： Bai Y,Yao HX,Hu ML,Wang LR,Jin LD,Wang WT,Lin LN

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:The SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery Score II (SS-II) can well predict 4-year mortality in patients with complex coronary artery disease (CAD), and guide decision-making between coronary artery bypass graft surgery and percutaneous coronary intervention (PCI)....

journal_title：Chinese medical journal

authors： He JQ,Yu XP,Peng C,Li Q,Luo YW,Gao YC,Zhang XL,Wu CY,Zhao H,Zhang YC,Liu JH,Lyu SZ,Chen F

更新日期：2015-08-20 00:00:00

abstract：BACKGROUND:Hospital-acquired pneumonia (HAP) is the most common hospital-acquired infection in China with substantial morbidity and mortality. But no specific risk assessment model has been well validated in patients with HAP. The aim of this study was to investigate the published risk assessment models that could pote...

journal_title：Chinese medical journal

authors： Wen JN,Li N,Guo CX,Shen N,He B

更新日期：2020-12-03 00:00:00

abstract：:Dot-ELISA assay was compared with standard Sandwich ELISA in detecting parasite antigen in sera from patients with bancroftian filariasis. The same monoclonal antibody and the same serum samples were used in both assays. With Dot-ELISA, 67 of 70 serum samples from microfilaremic patients were positive at a dilution of...

journal_title：Chinese medical journal

authors： Zheng HJ,Fuhrman JA,Xu M,Cheng WF,Reddy MV,Piessens WF

更新日期：1990-09-01 00:00:00

abstract：Background:Endometriosis is a challenging disease with symptoms such as dysmenorrhea and infertility. However, its etiology is still vague and there is still no effective markers or treatment. This study aimed to profile the circular RNAs (circRNAs) expressed in eutopic endometrium from patients with ovarian endometrio...

journal_title：Chinese medical journal

authors： Xu XX,Jia SZ,Dai Y,Zhang JJ,Li XY,Shi JH,Leng JH,Lang JH

更新日期：2018-03-05 00:00:00

abstract：BACKGROUND:Homoharringtonine (HHT) is a cephalotaxine ester derived from an evergreen tree found wildely throughout southern China, which has antileukemic activities against a variety of acute myeloid leukemic cells. For the sake of illustrating the mechanisms of HHT in the treatment of leukemia, we assessed the effect...

journal_title：Chinese medical journal

authors： Mai WY,Lin MF

更新日期：2005-03-20 00:00:00

abstract：:Atrial fibrillation (AF) is the most common sustained dysrhythmia in clinical practice. The bulk of evidence suggests that inflammatory processes, oxidative stress and matrix metalloproteinase are associated with development of AF. However, these agents may be involved in high mobility group box 1 protein (HMGB1). We ...

journal_title：Chinese medical journal

authors： Hu XR,Wang XH,Liu HF,Zhou WJ,Jiang H

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To analyze the effect and mechanism of hyperbaric oxygen (HBO) treatment for severe brain injury (SBI). METHODS:Fifty-five patients were divided into a treatment group of 35 patients and a control group of 20 patients. We observed the alterations of clinical, brain electric earth map (BEAM), endothelin (ET) ...

journal_title：Chinese medical journal

authors： Ren H,Wang W,Ge Z,Zhang J

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Epinephrine has been used as a first-choice vasopressor drug for cardiac arrest (CA) since 1974. However, the administration of epinephrine is controversial. This study aims to compare the effects of Shen-Fu injection (SFI) and epinephrine on resuscitation outcomes in a porcine model of prolonged CA. METHOD...

journal_title：Chinese medical journal

authors： Yin W,Guo Z,Li C

更新日期：2014-01-01 00:00:00