Clinical, brain electric earth map, endothelin and transcranial ultrasonic Doppler findings after hyperbaric oxygen treatment for severe brain injury.

Abstract:

OBJECTIVE:To analyze the effect and mechanism of hyperbaric oxygen (HBO) treatment for severe brain injury (SBI). METHODS:Fifty-five patients were divided into a treatment group of 35 patients and a control group of 20 patients. We observed the alterations of clinical, brain electric earth map (BEAM), endothelin (ET) and transcranial ultrasonic Doppler (TCD) findings before and after HBO treatment as well as outcome. RESULTS:In the treatment group, Glasgow coma scale, BEAM and outcome improved after HBO treatment; compared with that of the control group, it showed a significant difference. After one course of treatment, treatment group ET was reduced from 91.24 +/- 12.18 ng/L to 68.88 +/- 14.37 ng/L (P < 0.01); in control group, ET was reduced from 90.78 +/- 15.71 ng/L to 83.12 +/- 12.22 ng/L, with a statistically significant difference (P < 0.05). TCD records of MCA mean velocity (Vm) was reduced from 64.2 +/- 4.8 cm/s to 51.6 +/- 4.2 cm/s (P < 0.01), and a decrease in MCA systolic velocity (Vs) and pulse index (PI) values was statistically significant (P < 0.01). CONCLUSION:HBO treatment can improve the clinical, BEAM and outcome of severely brain injured patients, by decreasing acute stage ET and improving the blood velocity of MCA and decreasing cerebral vascular resistance. HBO treatment can reduce cerebral vascular spasms, cerebral ischemia and hypoxia. One of the important mechanisms of HBO treatment for severe brain injury is the lowering of intracranial pressure.

journal_name

Chin Med J (Engl)

journal_title

Chinese medical journal

authors

Ren H,Wang W,Ge Z,Zhang J

keywords:

subject

Has Abstract

pub_date

2001-04-01 00:00:00

pages

387-90

issue

4

eissn

0366-6999

issn

2542-5641

journal_volume

114

pub_type

杂志文章
  • Vitamin D and calcium metabolism in children with nephrotic syndrome of normal renal function.

    abstract::This study demonstrates that there are distinct abnormalities of vitamin D and calcium metabolism in children with nephrotic syndrome (NS) and normal renal function. In patients with active NS, serum calcium, ionized calcium, 25-OHD3 and CT were decreased, plasma PTH level was increased and serum ALP was elevated. The...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Huang JP,Bai KM,Wang BL

    更新日期:1992-10-01 00:00:00

  • Variation analysis of the severe acute respiratory syndrome coronavirus putative non-structural protein 2 gene and construction of three-dimensional model.

    abstract:BACKGROUND:The rapid transmission and high mortality rate made severe acute respiratory syndrome (SARS) a global threat for which no efficacious therapy is available now. Without sufficient knowledge about the SARS coronavirus (SARS-CoV), it is impossible to define the candidate for the anti-SARS targets. The putative ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Lu JH,Zhang DM,Wang GL,Guo ZM,Zhang CH,Tan BY,Ouyang LP,Lin L,Liu YM,Chen WQ,Ling WH,Yu XB,Zhong NS

    更新日期:2005-05-05 00:00:00

  • Correlation between retinal fluorescein angiography and blood viscosity and other factors in patients with primary open angle glaucoma.

    abstract:OBJECTIVE:To investigate the correlation among retinal fluorescein angiography, blood viscosity, and other factors in patients with open angle glaucoma (POAG). METHODS:Multiple step regression analysis was made to investigate the correlation between each of the following blood vessel filling times: the arm-choroid (A-...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Liu X,Zhou W,Ye T,Ge J,Cai X,Cheng A,Lin Y,Liang L,Tang H,Chen Z

    更新日期:1997-09-01 00:00:00

  • Coexisting ankylosing spondylitis and rheumatoid arthritis: a case report with literature review.

    abstract::A 30-year-old female patient with coexisting ankylosing spondylitis and rheumatoid arthritis was diagnosed and treated. The human leukocyte antigen (HLA)-B27 is a predisposing factor of ankylosing spondylitis and HLA-DR4 is a predisposing factor of rheumatoid arthritis. This patient was HLA-B27 and HLA-DR4 positive, a...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Guo YY,Yang LL,Cui HD,Zhao S,Zhang N

    更新日期:2011-10-01 00:00:00

  • Clinical observation of gastric bypass in treatment of type 2 diabetes.

    abstract:BACKGROUND:Roux-en-Y gastric bypass (GBP) is the main surgical procedure used in type 2 diabetes. The objective of this study was to evaluate the different types of GBP in treatment of type 2 diabetes. METHODS:Patients with type 2 diabetes were randomly divided into two groups: those who underwent gastrojejunal loop a...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Pu YD,Li JQ,Cao ZY,Wang L,Hu X,Dong LG,Li YM,Zhao HZ,Qin R,Yang B,He JM,Wu YJ,Wang Y,Lü G,Zhang B,Wang Y,Liu WP,Weng JF

    更新日期:2012-06-01 00:00:00

  • Role of peroxisome proliferator-activated receptor alpha activation in acute myocardial damage induced by isoproterenol in rats.

    abstract:BACKGROUND:Peroxisome proliferator-activated receptor (PPAR) alpha is one of the subtypes of PPARs. It regulates metabolism of lipid and lipoprotein, as well as glucose homeostasis. In addition, PPARalpha influences cellular proliferation, inflammation, differentiation and apoptosis, which plays a vital role in cardiov...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Yuan J,Wu J,Hang ZG,Zhong XK,Zhou LW,Yu B

    更新日期:2008-08-20 00:00:00

  • Establishment of multidrug-resistance cell line C(6)/adr and reversal of drug-resistance.

    abstract:OBJECTIVE:To investigate the mechanism of multidrug resistance (MDR) in a human glioma cell and methods for overcoming multi-drug resistance. METHODS:MDR cell line C(6)/adr was established. The expression of the mdr-1 gene and its P-glycoprotein (P-gp) in the C(6)/adr cell line was observed by RT-PCR and flow cytometr...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.3901/jme.2002.supp.238

    authors: Liu F,Wang C,Zhang Q,Li J,Zhang Y

    更新日期:2002-02-01 00:00:00

  • Hepatic arterial chemoembolization with CDDP microcapsules. Experimental studies.

    abstract::After cis-diamminedichloroplatinum ethylcellulose microcapsules (CDDPmc) and unencapsulated CDDP were infused into the hepatic arteries of New Zealand rabbits, both CDDP concentrations in the circulating blood and in hepatic tissue were measured at different time intervals. In the rabbits infused with CDDPmc, the CDDP...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang Y,Wu MC,Zhang XH

    更新日期:1992-02-01 00:00:00

  • Polymorphism on chromosome 9p21.3 contributes to early-onset and severity of coronary artery disease in non-diabetic and type 2 diabetic patients.

    abstract:BACKGROUND:Susceptibility to coronary artery disease (CAD) and diabetes is encoded by distinct, tightly-linked single nucleotide polymorphisms on chromosome 9p21. This study aimed to examine the association of variant rs1333049 on chromosome 9p21.3 with early-onset and severity of CAD in Chinese patients with and witho...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.3901/jme.2011.08.066

    authors: Wang W,Peng WH,Lu L,Zhang RY,Zhang Q,Wang LJ,Chen QJ,Shen WF

    更新日期:2011-01-01 00:00:00

  • Prognostic Value of Gai's Plaque Score and Agatston Coronary Artery Calcium Score for Functionally Significant Coronary Artery Stenosis.

    abstract:BACKGROUND:The prognostic values of the coronary computed tomography angiography (CCTA) score for predicting future cardiovascular events have been previously demonstrated in numerous studies. However, few studies have used the rich information available from CCTA to detect functionally significant coronary lesions. We...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.194636

    authors: Zhang C,Yang S,Gai LY,Han ZQ,Xin Q,Yang XB,Yang JJ,Jin QH

    更新日期:2016-12-05 00:00:00

  • Evaluation of clinical application of ESICM acute gastrointestinal injury grading system: a single-center observational study.

    abstract:BACKGROUND:In 2012, the working group on abdominal problems of the European Society of Intensive Care Medicine (ESICM) proposed a definition and also guidelines for the grading system and treatment of acute gastrointestinal injury (AGI). Until now, clinical reports on this topic have not been available, and the practic...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhang D,Li N,Dong L,Fu Y,Liu Z,Wang Y

    更新日期:2014-01-01 00:00:00

  • T helper cells in patients with chronic hepatitis B virus infection.

    abstract:OBJECTIVE:To investigate the compositions of Th1/Th2/Th3 cells in chronic hepatitis B virus (HBV)-infected individuals by determining the expression of interleukin-4 (IL-4), inetrferon-gamma (IFN-gamma), and transform growth factor-beta (TGF-beta) in single CD4(+) T cells isolated from peripheral blood mononuclear cell...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Jiang R,Feng X,Guo Y,Lu Q,Hou J,Luo K,Fu N

    更新日期:2002-03-01 00:00:00

  • Effect of artificial colloids on blood coagulation during shock stage of severe burn injury.

    abstract:BACKGROUND:There are controversies about the use of artificial colloids. This research was aimed to determine the effect of various artificial colloids on blood coagulation in the shock stage of severe burn injury. METHODS:Totally, 18 female Ba-Ma mini-pigs were subjected to a 40% total body surface third-degree flame...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhou JJ,Xing N,Chen J,Shi JW,Su GL

    更新日期:2013-01-01 00:00:00

  • Mechanisms of selective head cooling for resuscitating damaged neurons during post-ischemic reperfusion.

    abstract:OBJECTIVE:To evaluate the efficacy and the mechanism of application of selective head cooling on neuronal morphological damage during postischemic reperfusion in a rabbit model. METHODS:168 New Zealand rabbits were randomized into three groups. Group I [n = 24, (38 +/- 0.5) degrees C, non-ischemic control]; Group II [...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Duan M,Li D,Xu J

    更新日期:2002-01-01 00:00:00

  • J wave syndromes: a decade of progress.

    abstract:OBJECTIVE:The objective was to provide a brief history of J wave syndromes and to summarize our current understanding of their molecular, ionic, cellular mechanisms, and clinical features. We will also discuss the existing debates and further direction in basic and clinical research for J wave syndromes. DATA SOURCES:...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,评审

    doi:10.4103/0366-6999.154320

    authors: Li GL,Yang L,Cui CC,Sun CF,Yan GX

    更新日期:2015-04-05 00:00:00

  • Na (+) /Ca (2+) Exchanger 3 is Downregulated in the Hippocampus and Cerebrocortex of Rats with Hyperthermia-induced Convulsion.

    abstract:BACKGROUND:Na + /Ca 2+ exchanger (NCX) plays a crucial role in pentylenetetrazol-induced convulsion. However, it is unclear whether NCX is critically involved in hyperthermia-induced convulsion. In this study, we examined the potential changes in NCX3 in the hippocampus and cerebrocortex of rats with hyperthermia-induc...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.169103

    authors: Sun D,Xiao JH,Bai Y,Chen MS,Hu JS,Wu GF,Mao B,Wu SH,Hu Y

    更新日期:2015-11-20 00:00:00

  • Liver transplantation for hepatic metastatic pancreatic insulinoma with a survival over five years.

    abstract::Pancreatic neuroendocrine tumors (NETs) are one subgroup of gastroenteropancreatic NETs. Its main characteristics are slow growth, frequent metastasis to the liver, and limited to the liver for long periods. In patients with irresectable liver metastatic NET, liver transplantation is the only radical treatment. About ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Chen XB,Yang J,Xu MQ,Yan LN

    更新日期:2012-08-01 00:00:00

  • Changes in Ca2+-ATPase in a guinea pig endolymphatic hydrops model.

    abstract:OBJECTIVE:To investigate the localization of Ca(2+)-ATPase (Ca(2+) pump) in the cochlear and its change after endolymphatic hydrops, and to study the relationship between compound action potential (CAP) threshold and the Ca(2+)-ATPase activety. METHODS:The left endolymphatic sac was ablated to induce endolymphatic hyd...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhang S,Yang W,Sun J,Zhao C,Zhou N

    更新日期:2002-08-01 00:00:00

  • Chinese patients with transient ischemic attacks.

    abstract::In 123 cases of transient ischemic attacks, 72 were followed up for 22 years. The percentage of complete stroke was 46.5% and the fatality rate 47.9%. Causes of death, survival rate by life table, limitation of indication of neurovascular surgical operation and rehabilitation of survived patients were studied. The cau...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang XD

    更新日期:1990-09-01 00:00:00

  • Soft tissue release on the concave side in the treatment of scoliosis. A preliminary report of 23 cases.

    abstract::Since February 1982, 23 patients with scoliosis were treated by releasing the soft tissues on the concave side and plaster spinal fusion jacket. Of these patients, 13 had congenital scoliosis and 10 idiopathic scoliosis. Follow-up for 1 to 8.5 years showed that the results of correction were satisfactory. The maximum ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Dong L

    更新日期:1992-02-01 00:00:00

  • Morphological evidence of telocytes in mice aorta.

    abstract:BACKGROUND:Telocytes (TCs) are a novel type of interstitial cells, which have been recently described in a large variety of cavitary and noncavitary organs. TCs have small cell bodies, and remarkably thin, long, and moniliform prolongations called telopodes (Tps). Until now, TCs have been found in various loose connect...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.150102

    authors: Zhang HQ,Lu SS,Xu T,Feng YL,Li H,Ge JB

    更新日期:2015-02-05 00:00:00

  • Combination of medial patellofemoral ligament reconstruction with vastus medialis advancement for chronic patellar dislocation.

    abstract:BACKGROUND:The medial patellofemoral ligament (MPFL) reconstruction is popular in clinical practice for chronic patellar dislocation; however, the combination with vastus medialis advancement is rare. The aim of this study was to evaluate the clinical outcome of the combination of MPFL reconstruction with vastus medial...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang F,Kang HJ,Chen BC,Chen W,Su YL,Zhang YZ

    更新日期:2010-11-01 00:00:00

  • Pleomorphic xanthoastrocytoma in the lateral ventricle with extensive subarachnoid dissemination: report of a case and review of the literature.

    abstract::Pleomorphic xanthoastrocytoma (PXA) is a rare benign tumor that is usually located in the superficial cerebral hemisphere. Most reports of PXAs have included only a single case or small series. Therefore, the data with respect to the natural history of this tumor are fragmentary. We report a case of a PXA in the unusu...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Yang WQ,Huang B,Liang CH

    更新日期:2012-01-01 00:00:00

  • ESR spin trapping studies on the free radicals in gasphase of cigarette smoking.

    abstract::Free radicals in the gasphase of cigarette smoke were determined by spin trapping agent PBN (N-tert-butyl-2-phenyl nitrone) and DMPO (5,5-dimethyl-1-pyrroline-oxide) on electron spin resonance spectrometer. They were identified according to the spectrum parameters calculated from the spectra. The free radicals mainly ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhao BL,Yan LJ,Hou JW,Xin WJ

    更新日期:1991-07-01 00:00:00

  • Correlation between Electroencephalogram Alterations and Frontal Cognitive Impairment in Esophageal Cancer Patients Complicated with Depression.

    abstract:BACKGROUND:Some esophageal cancer patients complicated with depression exhibit cognitive impairments. Frontal electroencephalogram (EEG) may be used as a reliable biomarker for prefrontal-mediated cognitive functions. This study was to investigate alterations of EEG and frontal cognitive impairment in esophageal cancer...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.211552

    authors: Cao Y,Chen X,Xie H,Zou L,Hu LJ,Zhou XJ

    更新日期:2017-08-05 00:00:00

  • Lung-protective Ventilation in Patients with Brain Injury: A Multicenter Cross-sectional Study and Questionnaire Survey in China.

    abstract:BACKGROUND:Over the years, the mechanical ventilation (MV) strategy has changed worldwide. The aim of the present study was to describe the ventilation practices, particularly lung-protective ventilation (LPV), among brain-injured patients in China. METHODS:This study was a multicenter, 1-day, cross-sectional study in...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,多中心研究

    doi:10.4103/0366-6999.185869

    authors: Luo XY,Hu YH,Cao XY,Kang Y,Liu LP,Wang SH,Yu RG,Yu XY,Zhang X,Li BS,Ma ZX,Weng YB,Zhang H,Chen DC,Chen W,Chen WJ,Chen XM,Du B,Duan ML,Hu J,Huang YF,Jia GJ,Li LH,Liang YM,Qin BY,Wang XD,Xiong J,Yan LM

    更新日期:2016-07-20 00:00:00

  • Angiographic leakage of polypoidal choroidal vasculopathy on indocyanine angiography.

    abstract:BACKGROUND:There is no detailed report about the angiographic leakage of polypoidal choroidal vasculopathy (PCV) lesions on indocyanine green (ICG) angiography. This study aimed to investigate the angiographic leakage of polypoidal lesions in PCV on ICG angiography. METHODS:One hundred and forty-four eyes of 137 patie...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zuo CG,Wen F,Huang SZ,Luo GW,Yan H,Wu WJ,Wu DZ

    更新日期:2010-06-01 00:00:00

  • Relationship between Apolipoprotein Superfamily and Parkinson's Disease.

    abstract:OBJECTIVE:Parkinson's disease (PD) is featured with motor disorder and nonmotor manifestations including psychological symptoms, autonomic nervous system dysfunction, and paresthesia, which results in great inconvenience to the patients' life. The apolipoprotein (Apo) superfamily, as a group of potentially modifiable b...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,评审

    doi:10.4103/0366-6999.217092

    authors: Li L,Liu MS,Li GQ,Tang J,Liao Y,Zheng Y,Guo TL,Kang X,Yuan MT

    更新日期:2017-11-05 00:00:00

  • Effects of gypenosides on cellular immunity of gamma-ray-irradiated mice.

    abstract:OBJECTIVE:To investigate the effects of gypenosides (Gs) on cellular immunocompetence in the gamma-ray-irradiated mice. MATERIALS AND METHODS:Tested mice of ICR strain were treated continuously with Gs for 10 days before or after 4 Gy gamma-irradiation. Body weight and splenic weight of mice were measured. The blastog...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Hau DM,Feng Y,Chen WC,Lin IH,Chen KT,Lin SS,Wang MI

    更新日期:1996-02-01 00:00:00

  • Endovenous laser ablation of great saphenous vein with ultrasound-guided perivenous tumescence: early and midterm results.

    abstract:BACKGROUND:Endovenous laser ablation (EVLA) is an improved method to treat varicose great saphenous veins (GSV) with a high satisfactory rate. This study aimed to evaluate the efficiency and safety of treatment by EVLA procedures with ultrasound-guided perivenous tumescence. METHODS:Thirty-one patients (31 limbs) with...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Chen JQ,Xie H,Deng HY,Yuan K,Zhang JW,Zhang H,Zhang L

    更新日期:2013-02-01 00:00:00