Abstract:
:The 10% ethanol extract of the aerial parts of Calligonum comosum (50--400 mg/kg, i.p.) significantly reduced the increase in hind paw oedema induced by carrageenan in rats. Following sub-acute oral administration of the extract (50 and 100 mg/kg, daily for 14 days), a significant anti-inflammatory activity in the cotton pellet model was observed. Pre-treatment with the extract (100, 200 and 400 mg/kg) produced a significant and dose-dependent inhibition to the acute gastric ulcers induced by phenylbutazone, indomethacin, 0.2 N NaOH and 80% ethanol.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Liu XM,Zakaria MN,Islam MW,Radhakrishnan R,Ismail A,Chen HB,Chan K,Al-Attas Adoi
10.1016/s0367-326x(01)00271-4keywords:
subject
Has Abstractpub_date
2001-06-01 00:00:00pages
487-91issue
5eissn
0367-326Xissn
1873-6971pii
S0367-326X(01)00271-4journal_volume
72pub_type
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