Nongonadal LH/hCG receptors in pig: functional importance and parallels to human.

abstract：:The hypothalamus-pituitary-gonadal (HPG) axis is the most critical modulator of reproductive function. Genetic or environmental insults to the HPG axis during developmental windows can persist into adulthood, and processes such as gonadal hormone synthesis, timing of puberty, and fertility can be affected. At the leve...

journal_title：Seminars in reproductive medicine

authors： Biehl MJ,Raetzman LT

更新日期：2017-03-01 00:00:00

abstract：:Anejaculation within the context of a male infertility evaluation can be a distressing condition for patients. A variety of causes for anejaculation have been identified, and although the condition cannot be reversed, in many cases a minimally invasive treatment is feasible, allowing the patient to pursue his desire f...

journal_title：Seminars in reproductive medicine

authors： Ohl DA,Quallich SA,Sønksen J,Brackett NL,Lynne CM

更新日期：2009-03-01 00:00:00

abstract：:Vasomotor symptoms, including hot flushes and night sweats, pose a significant symptomatic burden to women undergoing menopause, and negatively impact on both their physical and psychological well-being. Management of these symptoms can be challenging, with the use of conventional hormone replacement therapy limited b...

journal_title：Seminars in reproductive medicine

authors： Modi M,Dhillo WS

更新日期：2019-05-01 00:00:00

abstract：:Whereas the importance of close monitoring and tight glycemic control in diabetic pregnancies cannot be ignored, the growing body of knowledge surrounding the different effects of diabetes mellitus on the earliest stages of reproduction underscores the need for aggressive screening among reproductive-aged women at ris...

journal_title：Seminars in reproductive medicine

authors： Jungheim ES,Moley KH

更新日期：2008-03-01 00:00:00

abstract：:Intrauterine insemination (IUI) is a widely used fertility treatment for couples with male and/or non-male factor infertility and is a relatively simple and inexpensive procedure. When used for unexplained infertility, IUI combined with ovarian stimulation increases the pregnancy rates, but evidence does not support t...

journal_title：Seminars in reproductive medicine

authors： Kim YJ,Park CW,Ku SY

更新日期：2014-07-01 00:00:00

abstract：:Noncommunicable diseases (NCDs), long considered diseases of little significance to global health, represent the greatest threat to economic development and human health. The main NCDs-diabetes, cancer, cardiovascular disease, and chronic respiratory disease-are the world's number one killer and bear the greatest burd...

journal_title：Seminars in reproductive medicine

authors： Marrero S,Adashi EY

更新日期：2015-01-01 00:00:00

abstract：:Gonadotropin-releasing hormone agonist (GnRHa) administration for the induction of oocyte maturation during in vitro fertilization treatment is effective in the prevention of ovarian hyperstimulation syndrome (OHSS). However, some studies have reported a lower ongoing pregnancy rate after GnRHa trigger. The excellent ...

journal_title：Seminars in reproductive medicine

authors： Engmann L,Benadiva C

更新日期：2010-11-01 00:00:00

abstract：:The ability of glycerol to protect cells from freezing injury was discovered accidentally. The subsequent development of cryopreservation techniques has had a huge impact in many fields, most notably in reproductive medicine. Freezing injury has been shown to have two components, direct damage from the ice crystals an...

journal_title：Seminars in reproductive medicine

authors： Pegg DE

更新日期：2002-02-01 00:00:00

abstract：:Despite the critical role the placenta plays in governing the outcome of pregnancy, a great deal remains to be learned about this transient organ. Several factors have contributed to our relative lack of knowledge. For example, most of the placenta's development, which precedes that of the embryo or fetus, occurs duri...

journal_title：Seminars in reproductive medicine

authors： Fisher SJ

更新日期：2000-01-01 00:00:00

abstract：:Pelvic pain, acute or chronic, accounts for more than 10% of referrals to gynecologists. Pain accounts for more than 40% of gynecologic diagnostic laparoscopies. Predicting operative findings is critical in planning surgical interventions, as well as preoperative and postoperative medical therapy. Ultrasound is useful...

journal_title：Seminars in reproductive medicine

authors： Shwayder JM

更新日期：2008-05-01 00:00:00

abstract：:The maternal-fetal environment plays an important role in developmental programming of adult disease. Metabolic and hormonal dysfunction during human fetal development accompanies gestational diabetes as a common occurrence in mothers with polycystic ovary syndrome (PCOS), while human fetal androgen excess from congen...

journal_title：Seminars in reproductive medicine

authors： Dumesic DA,Goodarzi MO,Chazenbalk GD,Abbott DH

更新日期：2014-05-01 00:00:00

abstract：:The constructs and the provision of preconception and obstetrical care have historically been based on the assumption of heterosexuality, and have often excluded lesbian women. However, due to significant strides in lesbian, gay, bisexual, transgender, and queer (LGBTQ) civil rights, more lesbian women desire to creat...

journal_title：Seminars in reproductive medicine

authors： Bushe S,Romero IL

更新日期：2017-09-01 00:00:00

abstract：:Male infertility is a condition that affects approximately 50% of infertile couples and about 30% of those couples have only male factor infertility identified. There has been speculation that male military service members may have an even greater lifetime prevalence of infertility as compared to the general populatio...

journal_title：Seminars in reproductive medicine

authors： Reed-Maldonado AB,Madden KC

更新日期：2019-01-01 00:00:00

abstract：:Couples experiencing recurrent pregnancy loss are often concerned that toxins within the environment have contributed to their reproductive difficulty. Questions posed by these couples to their health care providers are difficult to answer because scientifically accurate information regarding the reproductive impact o...

journal_title：Seminars in reproductive medicine

authors： Gardella JR,Hill JA 3rd

更新日期：2000-01-01 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) has become increasingly common over recent years and is associated with reproductive features as well as cardiometabolic risk factors, including visceral obesity, dyslipidemia and impaired glucose homeostasis, and potentially cardiovascular disease. Emerging evidence suggests that thes...

journal_title：Seminars in reproductive medicine

authors： Shorakae S,Teede H,de Courten B,Lambert G,Boyle J,Moran LJ

更新日期：2015-07-01 00:00:00

abstract：:Primary ovarian insufficiency (POI) compromises a woman's chance of conceiving with her own oocytes. Although biomarkers such as serum follicle-stimulating hormone, serum antimüllerian hormone, and assessment of antral follicle count by transvaginal ultrasound can give some general idea about ovarian activity and perh...

journal_title：Seminars in reproductive medicine

authors： Baker V

更新日期：2011-07-01 00:00:00

abstract：:Trophoblast cells of the murine placenta are derived from the trophectoderm (TE) cells of the preimplantation embryo. Establishment of the TE cell lineage is the result of a cell segregation event early in blastomere division. Models of cell lineage segregation suggest it is driven by the internalization of spatial in...

journal_title：Seminars in reproductive medicine

authors： Underhill LA,Robins JC

更新日期：2016-01-01 00:00:00

abstract：:Contraceptive vaginal rings (CVRs) contain sex steroids that diffuse through a plastic polymer ring at a constant rate and are absorbed directly through the vaginal epithelium into the systemic circulation. This delivery system provides many advantages over oral contraceptives (OCs), including avoidance of the first-p...

journal_title：Seminars in reproductive medicine

authors： Harwood B,Mishell DR Jr

更新日期：2001-12-01 00:00:00

abstract：:Aromatase p450 (p450arom) is the key enzyme for biosynthesis of estrogen, which is an essential hormone for the establishment and growth of endometriosis. There is no detectable aromatase enzyme activity in normal endometrium; therefore, estrogen is not locally produced in endometrium. Endometriosis tissue, however, c...

journal_title：Seminars in reproductive medicine

authors： Bulun SE,Fang Z,Imir G,Gurates B,Tamura M,Yilmaz B,Langoi D,Amin S,Yang S,Deb S

更新日期：2004-02-01 00:00:00

abstract：:Subclinical hypothyroidism has been found to be associated with adverse reproductive outcomes, such as infertility, miscarriage, preterm birth, and complications of pregnancy. Multiple studies have investigated the relationships between thyroid function, thyroid antibodies, fertility, and pregnancy. Thyroid autoimmuni...

journal_title：Seminars in reproductive medicine

authors： Seungdamrong A

更新日期：2016-11-01 00:00:00

abstract：:In recent years, there has been increasing concern regarding the safety of in vitro fertilization (IVF) because of the potential health impact on these infants. Multiple pregnancy contributes the vast majority of morbidity associated with IVF and, initially, many thought that adverse outcomes after IVF were solely att...

journal_title：Seminars in reproductive medicine

authors： Kalra SK,Molinaro TA

更新日期：2008-09-01 00:00:00

abstract：:Women with polycystic ovary syndrome (PCOS) most often seek treatment for reduction of hair growth and/or acne, restoration of menstrual cyclicity, and infertility. In addition, these patients are increasingly seeking advise and treatment for the metabolic abnormalities related to PCOS (e.g., insulin resistance and ty...

journal_title：Seminars in reproductive medicine

authors： Ehrmann DA,Rychlik D

更新日期：2003-08-01 00:00:00

abstract：:Minimally invasive gynecologic surgery is continuously pushing its limits by embracing ever more sophisticated technology. This is also true for reproductive surgery, arguably the birthplace of gynecologic endoscopy, where minimally invasive treatment of uterine, tubal, ovarian, and peritoneal pathology has long becom...

journal_title：Seminars in reproductive medicine

authors： Gargiulo AR,Nezhat C

更新日期：2011-03-01 00:00:00

abstract：:The birth of a child with ambiguous genitalia is a challenging and distressing event for the family and physician and one with life-long consequences. Most disorders of sexual differentiation (DSD) associated with ambiguous genitalia are the result either of inappropriate virilization of girls or incomplete virilizati...

journal_title：Seminars in reproductive medicine

authors： Wilson JD,Rivarola MA,Mendonca BB,Warne GL,Josso N,Drop SL,Grumbach MM

更新日期：2012-10-01 00:00:00

abstract：:In this article the role of LH receptor gene mutations in patients with aberrant sex differentiation is discussed. In a dominant autosomal familial form of precocious puberty in boys (familial male-limited precocious puberty) LH receptor gene mutations have been identified. These single amino acid changes, mostly foun...

journal_title：Seminars in reproductive medicine

authors： Themmen AP,Verhoef-Post M

更新日期：2002-08-01 00:00:00

abstract：:Complementary therapies and medicines are a broad and diverse range of treatments, and are frequently used by women and their partners during the preconception period to assist with infertility, and to address pregnancy-related conditions. Despite frequent use, the evidence examining the efficacy, effectiveness, and s...

journal_title：Seminars in reproductive medicine

authors： Smith CA,Armour M,Ee C

更新日期：2016-03-01 00:00:00

abstract：:As sperm traverse the female tract from vagina to oocyte, they experience a steroid milieu, which due to transcriptional inactivity, they can only respond to via non-genomic signaling. This environment mediates events including capacitation, changes in motility patterns, chemotaxis, and acrosome reaction. Current know...

journal_title：Seminars in reproductive medicine

authors： Correia JN,Conner SJ,Kirkman-Brown JC

更新日期：2007-05-01 00:00:00

abstract：:Pregnancy results in major changes in the hypothalamo-pituitary-adrenal (HPA) axis, which in turn influence fetal growth and the timing of labor. From the beginning of the second trimester maternal cortisol secretion increases, and in late pregnancy the placenta, in large part mediated through corticotroph-releasing h...

journal_title：Seminars in reproductive medicine

authors： Trainer PJ

更新日期：2002-11-01 00:00:00

abstract：:Identifying appropriate candidates for menopausal hormone therapy (HT) is challenging given the complex profile of risks and benefits associated with treatment. Most professional societies agree that HT should not be used for chronic disease prevention. Recent findings from the Women's Health Initiative and other rand...

journal_title：Seminars in reproductive medicine

authors： Wild RA,Manson JE

更新日期：2014-11-01 00:00:00

abstract：:Inhibin is a dimeric glycoprotein that suppresses follicle-stimulating hormone (FSH) secretion from the pituitary. Two bioactive forms of inhibin exist, inhibin A and B. The availability of specific immunoassays for each of the isoforms has enabled the study of the individual inhibins and their physiological roles. In...

journal_title：Seminars in reproductive medicine

authors： O'Connor AE,De Kretser DM

更新日期：2004-08-01 00:00:00