Abstract:
:The concept of a group of headaches whose pathophysiological focus revolves around the trigeminal-autonomic reflex fills a useful gap in characterising a number of primary headache syndromes. Broadly, these syndromes involve activation of trigeminovascular nociceptive pathways with reflex cranial autonomic activation. Clinically, this physiology predicts pain with some combination of lacrimation, conjunctival injection, nasal congestion, or eyelid oedema. Several of the primary neurovascular headaches, notably cluster headache, paroxysmal hemicrania and short-lasting neuralgiform pain with conjunctival injection and tearing (SUNCT), seem to immediately fit this classification. This physiology also explains why some patients with migraine present cranial autonomic features, and the concept is thus broadly useful for clinicians seeking a pathophysiological understanding of the primary neurovascular headaches. Given the known pathophysiology one can place the various treatments aimed at preventing these headaches or indeed treating the acute attacks, into context.
journal_name
Acta Neurol Belgjournal_title
Acta neurologica Belgicaauthors
Goadsby PJkeywords:
subject
Has Abstractpub_date
2001-03-01 00:00:00pages
10-9issue
1eissn
0300-9009issn
2240-2993journal_volume
101pub_type
杂志文章,评审abstract:: ...
journal_title:Acta neurologica Belgica
pub_type:
doi:10.1007/s13760-018-1035-4
更新日期:2018-12-01 00:00:00
abstract:UNLABELLED:Although there only have been a limited number of double-blind, placebo controlled trials, antipsychotics are considered to be effective drugs for the treatment of tics in Gilles de la Tourette syndrome (GTS). Evidence concerning the efficacy of olanzapine and other atypical antipsychotics in the treatment o...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2005-12-01 00:00:00
abstract::A case of femoral palsy associated with chronic pain sensible to Carbamazepine, secondary to iliacus haematoma during anticoagulant therapy is reported. Late femoral nerve decompression followed by transcutaneous neurostimulation permit the normalization of the sensory nerve conduction and a complete clinical recovery...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1985-11-01 00:00:00
abstract::The purpose of the study was to evaluate the relationship between sympathetic skin responses (SSR), electrodiagnostic reflex activities (F wave, H reflex), and functional capacity in post-stroke patients. The study comprised 40 hemiplegia patients (mean age 57.8 ± 10.9 years) and 40 healthy volunteers (mean age 557 ± ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-014-0397-5
更新日期:2015-09-01 00:00:00
abstract::We report a 44-year-old female patient without any familial history of dementia presenting with increasing disturbances in behaviour and language followed by a progressive cognitive deterioration. Neuropsychological evaluation revealed a significant impairment on frontal lobe tests. A brain PET scan disclosed a severe...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract::Despite the huge health and economic burden of migraine headache, few medications have been approved for its prophylactic treatment, most of which can potentially induce serious adverse effects. Coenzyme Q10 (CoQ10) is a supplement and has shown preliminary benefits in migraine prophylaxis. We aimed to assess this eff...
journal_title:Acta neurologica Belgica
pub_type: 临床试验,杂志文章
doi:10.1007/s13760-016-0697-z
更新日期:2017-03-01 00:00:00
abstract::The objective of the study was to investigate the associations between the degree of edema with the clinical and biochemical parameters such as serum lactate dehydrogenase (LDH), albumin (ALB) in posterior reversible encephalopathy syndrome (PRES) patients. Forty-nine patients with typical clinical symptoms and charac...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-012-0060-y
更新日期:2012-09-01 00:00:00
abstract::Amyotrophic Lateral Sclerosis and CHARGE syndrome are complex neurological disorders, which never occurred together in the same family and, to date, no putative correlation between them has been described on PubMed Central. Due to our aim was to evaluate the presence of different genetic variants involved in these pat...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-018-1029-2
更新日期:2018-12-01 00:00:00
abstract:: ...
journal_title:Acta neurologica Belgica
pub_type: 信件
doi:10.1007/s13760-018-0951-7
更新日期:2018-12-01 00:00:00
abstract::Previous studies of multiple sclerosis (MS) patients have reported an inverse correlation between disability, the number of relapses and vitamin D levels in mostly white patients. It is unclear if this relationship has the same behavior in individuals with Hispanic backgrounds. To determine the relationship between vi...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-017-0834-3
更新日期:2018-03-01 00:00:00
abstract::Ulnar nerve lesions may occur at different sublocations at wrist and may involve various branches of the nerve. Standard neurophysiological studies are generally insufficient in revealing these lesions. Demonstration of conduction block and/or focal slowing of nerve conduction is the most definitive electrodiagnostic ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:2010-03-01 00:00:00
abstract::Functional brain imaging studies, such as positron emission tomography and functional nuclear magnetic resonance imaging, are based on the regional increases in cerebral blood flow, glucose consumption and oxygen consumption that are associated with regional increases in neuronal activity. The cellular basis of the si...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:2002-12-01 00:00:00
abstract::Small fiber neuropathy (SFN), due to loss of A-delta and unmyelinated C fibers, is a cause of neuropathic pain. Although the patients with vitamin B12 deficiency are included in SFN studies in the literature, there is no histopathological study investigating the small fiber loss solely in patients with vitamin B12 def...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-017-0847-y
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:FDG-PET in ALS most typically demonstrates a primary (and sometimes also supplementary) motor cortex hypometabolism, often associated with more diffuse cortical hypometabolism involving mostly the dorsolateral prefrontal cortex, the medial and lateral premotor cortices, and the bilateral insular cortex invol...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
abstract::A case of isolated cerebral vasculitis showing benign outcome is presented. Review of pertinent literature suggests that isolated benign arteritis of the CNS should be considered as a distinct entity, in a heterogeneous group of vasculitides. The common features of the syndrome are as follows: 1(0) benign evolution; 2...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1984-08-01 00:00:00
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:10.1007/s13760-012-0040-2
更新日期:2012-03-01 00:00:00
abstract::The authors study the characteristics of a group of 23 patients for whom an initial tentative diagnosis of Hakim-Adams syndrome (H-A syndrome) was eventually rejected. On account of several factors distinguishing these patients from the true H-A group, the authors propose using the term "pseudo Hakim-Adams syndrome". ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1982-07-01 00:00:00
abstract::A case of Refsum's disease in a 62-year-old man, with an ophthalmologic symptomatology dominated by a tight bilateral miosis, is reported. The miosis mechanism in this disease is discussed. The clinical evolution has been stabilized by a diet poor in phytanic acid. ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
abstract::Cisplatin is an anticancer agent widely used in the treatment of malignant tumors. One of the major adverse effects of cisplatin is its neurotoxicity. Memantine, an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, has been reported to have neuroprotective effects against neurological deficits. This study...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-019-01161-z
更新日期:2020-02-01 00:00:00
abstract::The aim of this study was to investigate personality, by means of the Rorschach Psychodiagnostic test, in a consecutive series of fourteen patients with Parkinson's disease (PD) submitted to bilateral deep brain stimulation of the subthalamic nucleus (DBS STN). Patients were evaluated pre-operatively and 1 year after ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2008-03-01 00:00:00
abstract::Smoking is associated with increased multiple sclerosis (MS) risk. In addition, some studies have reported that smoking is associated with anxiety and depression. However, the associations between smoking, walking, and fatigue are needed to be investigated. The objective was to investigate the associations between cig...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01341-2
更新日期:2020-03-28 00:00:00
abstract::Data examining the association between vitamin D and diabetic peripheral neuropathy are limited. This study investigated the serum levels of vitamin D, vitamin D-binding protein (VDBP), and vitamin D receptor (VDR) in diabetics in the Yozgat region of Turkey, and assessed their relationships with diabetic peripheral n...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-014-0304-0
更新日期:2015-03-01 00:00:00
abstract::Evidence suggests that symptoms of migraine are related to the involvement of the autonomic nervous system. Data on atrial conduction system are limited in migraineurs. We aimed to assess atrial electromechanical delay using tissue Doppler imaging (TDI) in patients with migraine. Forty-five migraine patients and age- ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-013-0273-8
更新日期:2014-12-01 00:00:00
abstract::Neuropraxia of the cervical spinal cord is a rare condition which is almost exclusively reported in American football players following cervical hyperextension or hyperflexion trauma. In this entity-neurological symptoms of both arms and legs for a period of up to 15 minutes are observed with complete recovery. We rep...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract::We describe an additional case of spastic paretic hemifacial contracture, an uncommon condition characterized by sustained unilateral contraction of the facial muscles associated with mild ipsilateral facial paresis. This entity has only rarely been associated with multiple sclerosis (MS) and can be mistaken for hemif...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-017-0817-4
更新日期:2017-12-01 00:00:00
abstract::Out of the various drugs which may be used in the treatment of intracramial hypertension we have tested long-acting Synacthen (Synacthen-dépot) in patients with inoperable cerebral tumours. The results were favourable, especially in the case of long-term treatment, since the delayed action of the drug allows flexible ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1976-07-01 00:00:00
abstract::Short-term cyclophosphamide pulse therapy was administered to five patients with idiopathic inflammatory myopathies (IIM) which were refractory to corticosteroids and, in two cases, to other aggressive therapies. Both disease remission and a reduction in corticosteroid dosage were obtained in four patients. Three of t...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::Despite intensive research efforts, the cause of the muscular dystrophies has remained elusive for many decades. In the late 1980s, major advances in molecular genetics have led to the discovery of the dystrophin gene and its protein product, dystrophin. Mutations in the dystrophin gene result in dystrophin deficiency...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:1995-01-01 00:00:00
abstract::We performed a retrospective study of 62 patients with syringomyelia. Most noteworthy among the clinical features in our patient population are the following: segmental sensory disturbances are usually less restrictive than the classical thermoanalgesia, pain is a presenting symptom in almost 50% of cases, and skeleta...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::In contrast to the classic, slowly progressive polyneuropathy in alcoholic patients, acute forms, clinically mimicking Guillain-Barré syndrome, are rare. We present a patient who developed motor weakness and sensory loss in all four limbs within four days. Laboratory data were consistent with long-term alcohol abuse a...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00