Abstract:
:Previous studies of multiple sclerosis (MS) patients have reported an inverse correlation between disability, the number of relapses and vitamin D levels in mostly white patients. It is unclear if this relationship has the same behavior in individuals with Hispanic backgrounds. To determine the relationship between vitamin D serum levels and disability in a sample of Hispanics of a Mexican background with relapsing-remitting multiple sclerosis (RRMS). A cross-sectional study was conducted on 50 RRMS individuals of Mexican background. The Expanded Disability Status Scale (EDSS) score, progression index (PI) and annual relapse rate (ARR) were recorded for each patient. Vitamin D levels were assessed during the summer. Pearson's test was used to evaluate the relationship between vitamin D and EDSS, PI, ARR, and duration of disease evolution. Most patients were females (n = 29, 58%). The mean vitamin D level was 22.3 (± 6.4) ng/ml; the mean EDSS score was 2.2 (± 0.7), ARR 1.3 (± 0.5) and PI1.08 (± 0.6). No correlation was found between vitamin D levels and EDSS scores, ARR, PI or duration of disease. Moderate negative association between vitamin D levels and EDSS was found just in females (<0.0001). No correlation between vitamin D levels and disability was found in this sample of RRMS Mexicans. Longitudinal studies are needed to better understand the impact of Vitamin D in disability and multiple time points.
journal_name
Acta Neurol Belgjournal_title
Acta neurologica Belgicaauthors
Rito Y,Flores J,Fernández-Aguilar A,Escalante-Membrillo C,Barboza MA,Amezcua L,Corona Tdoi
10.1007/s13760-017-0834-3subject
Has Abstractpub_date
2018-03-01 00:00:00pages
47-52issue
1eissn
0300-9009issn
2240-2993pii
10.1007/s13760-017-0834-3journal_volume
118pub_type
杂志文章abstract:OBJECTIVE:To study the impact of cognitive impairment and severity of dementia on the quality of life (QoL) of patients and their caregivers. DESIGN:Descriptive cross-sectional study within the NAtional Dementia Economic Study. SETTING:231 general practices and 15 specialist clinics in Belgium. SUBJECTS:605 patients...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
abstract::Progressive supranuclear palsy (PSP) is a severe neurodegenerative disease still lacking of alleviating treatments for either cognitive or motor disturbances. Aimed at widening the spectrum of therapeutic options, here, we describe efficacy and safety of a long-term treatment with Rotigotine, a non-ergolinic dopamine ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-018-0993-x
更新日期:2019-03-01 00:00:00
abstract::Celiac disease (CD) and non celiac gluten sensitivity (NCGS) can be responsible for neurological complications such as ataxia and peripheral neuropathies but also cognitive impairment. This cognitive involvement is variable in its expression, its duration and its prognosis ranging from transient and reversible subtle ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:10.1007/s13760-017-0870-z
更新日期:2018-03-01 00:00:00
abstract:PURPOSE:total removal of spinal hemangioblastomas with satisfactory clinical outcomes remains a challenge. We aimed to evaluate the surgical outcomes of our spinal hemangioblastomas patients, summarize our experiences with this condition and review-related literature. METHODS:records of 18 spinal hemangioblastoma pati...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01420-4
更新日期:2020-07-07 00:00:00
abstract::Small fiber neuropathy (SFN), due to loss of A-delta and unmyelinated C fibers, is a cause of neuropathic pain. Although the patients with vitamin B12 deficiency are included in SFN studies in the literature, there is no histopathological study investigating the small fiber loss solely in patients with vitamin B12 def...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-017-0847-y
更新日期:2018-09-01 00:00:00
abstract::Friedreich's ataxia (FRDA), an autosomal recessive disorder, is characterized by spinocerebellar degeneration and cardiomyopathy. Here we explore some of the putative mechanisms underlying the cardiomyopathy in FRDA that have been elucidated using different experimental models. FRDA is characterized by a deficiency in...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:2011-09-01 00:00:00
abstract::Appropriate treatment of neonatal seizures with an effective therapy is important in reducing long-term neurologic disabilities. Sixty-seven neonates, who received intravenous (IV) levetiracetam (LEV) as first-line therapy for treating seizures between 2013 and 2017 were evaluated retrospectively to investigate the ef...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01366-7
更新日期:2020-05-18 00:00:00
abstract::Out of the various drugs which may be used in the treatment of intracramial hypertension we have tested long-acting Synacthen (Synacthen-dépot) in patients with inoperable cerebral tumours. The results were favourable, especially in the case of long-term treatment, since the delayed action of the drug allows flexible ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1976-07-01 00:00:00
abstract::Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common heritable cause of stroke and vascular dementia in adults. We present a family from Serbia presenting with stroke and depression in the lack of vascular risk factors, with brain MRI indicating CADASI...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-012-0174-2
更新日期:2013-09-01 00:00:00
abstract::Inflammatory demyelinating polyradiculoneuropathy causes a spectrum of conditions ranging from acute (Guillain-Barré syndrome), through subacute to chronic forms. The pathogenesis of acute forms is related to antibody responses against glycolipid epitopes which mimic bacterial, especially Campylobacter jejuni, structu...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:2000-09-01 00:00:00
abstract::The large choice of antiepileptic drugs (AEDs) in Belgium complicates the selection of the appropriate product for the individual patient. International guidelines on the treatment of epilepsy have been published, but are not tailored to the Belgian situation. This publication presents recommendations from a group of ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,实务指引
doi:
更新日期:2008-12-01 00:00:00
abstract::Various statistical discrimination indices reveal deflections regarded as significant before the 20th ms after stimulation (probably equivalent to Bickford responses or subcortical activity) and between the 20th and 23rd ms (early fractions of MVER). The independence of signal and noise is discussed. Considerations co...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::The authors distinguish between two evolutive forms of dementia, one being chracterized by prpgressive deterioration (for instance in the course of arteriopathic, degenerative or infections processes) and the other in which dementia sets in after the clinical picture has improved (for instance after meningeal haemorrh...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1976-07-01 00:00:00
abstract::Nine cases (seven men and two women, mean age 64.5 years) of classical lacunar syndromes due to intracerebral hemorrhage are reported. Three patients presented with pure motor hemiparesis (two putaminal hematomas with proportional weakness and one cortical hemorrhage with brachio-crural hemiparesis). Four patients pre...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::The aim of this study was to test feasibility of transcranial Doppler (TCD) and single photon emission computed tomography (SPECT) during compound neuroactivation task. The study was performed in 60 healthy right-handed volunteers. Cerebral blood flow velocity was measured by TCD in both middle cerebral arteries (MCA)...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-012-0152-8
更新日期:2013-09-01 00:00:00
abstract::Febrile seizures (FS) are recognized as an antecedent to the development of temporal lobe epilepsy with hippocampal sclerosis (TLE-HS), but it is unclear whether prolonged FS are a direct cause of TLE-HS. Here, we used a rat model of infantile FS to study the effects of inflammatory cytokines on seizure susceptibility...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-013-0246-y
更新日期:2014-09-01 00:00:00
abstract::A case of isolated cerebral vasculitis showing benign outcome is presented. Review of pertinent literature suggests that isolated benign arteritis of the CNS should be considered as a distinct entity, in a heterogeneous group of vasculitides. The common features of the syndrome are as follows: 1(0) benign evolution; 2...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1984-08-01 00:00:00
abstract::CADASIL is an autosomal dominant inherited arteriopathy caused by a point mutation in the Notch3 gene. Classically, it is characterised by recurrent ischemic strokes, often resulting in mental decline. Intracerebral haemorrhages in CADASIL have rarely been reported. We describe a young male with a genetically proven C...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2006-12-01 00:00:00
abstract::This study investigates the correlation between brain magnetic resonance imaging findings and blink reflex abnormalities in patients with relapsing remitting multiple sclerosis. Twenty-six patients and 17 healthy subjects were included in this study. Blink reflex test (BRT) results were obtained using right and left s...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-012-0175-1
更新日期:2013-09-01 00:00:00
abstract::We present a case of partial rhombencephalosynapsis, diagnosed by magnetic resonance imaging (MRI), in fetus aged 27 gestational weeks, in a dizygotic twin pregnancy. The distinctive MRI features of this cerebellar malformation (segmental hypogenesis of the cerebellar vermis, partial fusion of the cerebellar hemispher...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2011-06-01 00:00:00
abstract::Public awareness is essential for the early diagnosis, treatment, and prevention of stroke. In particular, young adults represent an important avenue for increasing awareness and precluding the adoption of unhealthy, risk-increasing behaviors. This study was the first to investigate the basic knowledge of Korean adole...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-017-0754-2
更新日期:2017-06-01 00:00:00
abstract::A 68 year-old man developed progressive hemidystonia and chorea 8 months after a contralateral thalamic stroke. The neurological examination also showed a right pyramidal syndrome without hemiparesis, a right horizontal sectoranopia, and a right hemihypesthesia for all sensory modalities. The MRI revealed infarctions ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract::The aim of this study was to compare the incidence of postoperative, surgery-related complications in patients where fluorescein video angiography (FL-VA) was performed with those operated without intraoperative verification. This is an observational cohort study including 97 patients who were selected for microsurgic...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01365-8
更新日期:2020-05-06 00:00:00
abstract::Psychiatric comorbidity in patients with headache contributes to poorer prognosis, chronification of disease, poor response to treatment, increased cost of treatment, and decreased quality of life. The purpose of the present study was to evaluate the depressive symptoms in adolescents with chronic and episodic migrain...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-012-0135-9
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:The present study was designed to describe the characteristics, risk factors and prognosis of patients diagnosed with CVT in our center. METHOD:The present retrospective cross-sectional study was conducted on patients diagnosed with cerebral vein or sinus thrombosis based on the patients' clinical presentat...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2010-09-01 00:00:00
abstract::Guillain-Barré Syndrome (GBS) is best viewed as a clinical syndrome which can have at least two clinical substrates: the commonest is an acquired demyelinating polyradiculoneuropathy and the other is an acute motor axonal neuropathy. An acute acquired neuropathy can also sometimes cause the Miller Fisher syndrome of o...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract::Stroke is still a major cause of morbidity and mortality throughout the world, although better stratification and treatment modalities are being developed. As compared to ischemic stroke, intracerebral hemorrhage (ICH) possesses many unknown data and lacks guidelines for better prophylaxis. In this study, we aimed to ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-013-0222-6
更新日期:2013-12-01 00:00:00
abstract::The association of carotid atherosclerosis with silent brain infarcts (SBIs) and white matter lesions (WMLs) currently remains unknown. This study aims to compare SBIs, deep white matter lesions (DWMLs), and periventricular white matter lesions (PWMLs) in ipsilateral and contralateral hemispheres to internal carotid a...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01517-w
更新日期:2020-10-09 00:00:00
abstract::Myelin oligodendrocyte glycoprotein antibody (MOG-Ab) is involved in the pathogenesis of central nervous system (CNS) demyelination disorders. We aimed to explore the spectrum of MOG-Ab-associated diseases in eastern India. A single-center, prospective observational study was done over a period of 2 years in a tertiar...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01356-9
更新日期:2020-04-20 00:00:00
abstract:: ...
journal_title:Acta neurologica Belgica
pub_type: 信件
doi:10.1007/s13760-017-0846-z
更新日期:2019-03-01 00:00:00