Pathogenesis and treatment of inflammatory demyelinating polyradiculoneuropathy.

Abstract:

:Inflammatory demyelinating polyradiculoneuropathy causes a spectrum of conditions ranging from acute (Guillain-Barré syndrome), through subacute to chronic forms. The pathogenesis of acute forms is related to antibody responses against glycolipid epitopes which mimic bacterial, especially Campylobacter jejuni, structures but T cells are also involved. The pathogenesis of chronic forms is poorly understood. Different forms differ in their responses to steroids. Chronic inflammatory demyelinating polyradiculoneuropathy responds to steroids but a variant multifocal motor neuropathy and the acute forms of inflammatory demyelinating polyradiculoneuropathy do not. Acute and chronic forms respond to plasma exchange and intravenous immunoglobulin.

journal_name

Acta Neurol Belg

journal_title

Acta neurologica Belgica

authors

Hughes RA

keywords:

subject

Has Abstract

pub_date

2000-09-01 00:00:00

pages

167-70

issue

3

eissn

0300-9009

issn

2240-2993

journal_volume

100

pub_type

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