Abstract：
:The aim of this study was to investigate retinal nerve fiber layer (RNFL) thickness and macular changes (central subfield thickness, cube average thickness, cube volume) in patients with chronic migraine (CM) without visual impairment using spectral-domain optical coherence tomography (SD-OCT) and to compare the results to healthy controls. A total of 80 subjects, including 40 CM patients (24 females, 16 males, [corrected] at 19-36 years of age) with no migraine prophylactic treatment and 40 healthy controls (22 females, 18 males, [corrected] at 20-40 years of age) were enrolled. Both eyes of patients with CM and controls were imaged using Cirrus HD SD-OCT (Carl Zeiss Meditec, Dublin, CA, USA). The average RNFL thickness was not significantly thinner in patients with CM. The mean average RNFL thickness was 83 ± 10.5 μm in CM patients and 85 ± 9.6 μm in healthy controls (p = 0.648), but superior quadrant RNFL thickness in the CM patients was significantly lower than healthy controls. The mean superior RNFL thickness was 86 ± 6.7 μm in CM patients and 108 ± 7.3 μm in controls (p < 0.001). Illness duration and frequency of the attacks were not affected by RNFL thickness. No significant differences were detected in macular changes between CM patients and healthy controls. In our study, the thickness of superior RNFL was found to be thinner in CM patients. This implies that longitudinal follow-up is needed to clarify whether RNFL thinning, in migraine patients, is related to a progressive loss of axons and retinal ganglion cells.
journal_name
Acta Neurol Belgjournal_title
Acta neurologica Belgicaauthors
Kirbas S,Tufekci A,Turkyilmaz K,Kirbas A,Oner V,Durmus Mdoi
10.1007/s13760-012-0150-xsubject
Has Abstractpub_date
2013-06-01 00:00:00pages
167-72issue
2eissn
0300-9009issn
2240-2993journal_volume
113pub_type
杂志文章abstract：:We performed a retrospective study of 62 patients with syringomyelia. Most noteworthy among the clinical features in our patient population are the following: segmental sensory disturbances are usually less restrictive than the classical thermoanalgesia, pain is a presenting symptom in almost 50% of cases, and skeleta...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
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journal_title：Acta neurologica Belgica
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journal_title：Acta neurologica Belgica
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journal_title：Acta neurologica Belgica
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pub_type： 杂志文章,评审
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doi：
更新日期：2009-09-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
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journal_title：Acta neurologica Belgica
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更新日期：2001-06-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2007-03-01 00:00:00
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journal_title：Acta neurologica Belgica
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doi：
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
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pub_type： 杂志文章
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doi：
更新日期：2010-09-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
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journal_title：Acta neurologica Belgica
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更新日期：1976-07-01 00:00:00
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journal_title：Acta neurologica Belgica
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doi：
更新日期：1987-05-01 00:00:00
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更新日期：1996-03-01 00:00:00
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更新日期：2011-06-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
