Weight changes in Parkinson's disease patients after subthalamic nucleus deep brain stimulation surgery.

Abstract:

BACKGROUND:After Sub-Thalamic Nucleus Deep Brain Stimulation (STN-DBS), an effective treatment for Parkinson disease patients, weight gain has been observed. As this method of treatment is only in use since two years in Iran, no information regarding its side effects (including weight gain) existed thus far. OBJECTIVE:We conducted this study to evaluate the weight gain 1 and 3 months after the DBS surgery. METHODS:We enrolled all patients who underwent bilateral STN-DBS in Rasool Akram Hospital affiliated to Iran University of Medical Sciences in 2008- 2009. Unified Parkinson Disease Rating Scale (UPDRS), neuropsychological assessment, pulmonary and cardiac evaluation before the surgery were carried out for all patients. They were weighted before, 1 and 3 months after the STN-DBS. RESULTS:The average weight of patients was 70.7 +/- 14.4, 74.1 +/- 16.2 and 76.6 +/- 14.4 Kg before, 1 and 3 months after the STN-DBS, respectively (P < 0.037). CONCLUSION:Our results confirm that rapid weight gain (as soon as 1 month after surgery) occurred in STN-DBS treated parkinsonian patients.

journal_name

Acta Neurol Belg

journal_title

Acta neurologica Belgica

authors

Moghaddasi M,Boshtam M

subject

Has Abstract

pub_date

2010-12-01 00:00:00

pages

311-3

issue

4

eissn

0300-9009

issn

2240-2993

journal_volume

110

pub_type

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