Abstract：
:During a course of therapy by anticoagulants, 16 intracranial haemorrhages and 10 cerebral infarctions, were observed over a period of seven years. The intracranial haemorrhages include 11 subdural haematomas (four acute, seven chronic) and ive intracerebral haemorrhages, one of which resulted from the rupture of an arterial aneurysm. The anticoagulant therapy lasted in 12 cases for more than two years, and in four cases between twenty-four hours and two months. Monocoumarinics are most often the cause of the haemorrhages. The subdural haematomas are unpredictable and a traumatism was only observed in four cases. Three out of four patients with acute haematomas died, as well as two out of seven patients with chronic haematomas. Three out of four intracerebral haemorrhages occurred after ischemic cerebral accidents. The existence of a cerebral infarction counter-indicates the use of anticoagulants. The cerebral infarctions occurred five times during the anticoagulation therapy, and five times after stopping the treatment (from within a few days to a few weeks). Anticoagulation therapy, apart from infarction, is in general well supported and well supervised during the first weeks. Used for a long time, it may lead to very serious and often fatal complication, and must therefore be weighed against the advantages of the treatment.
journal_name
Acta Neurol Belgjournal_title
Acta neurologica Belgicaauthors
Petrov V,Bonnal Jkeywords:
subject
Has Abstractpub_date
1975-09-01 00:00:00pages
205-18issue
5eissn
0300-9009issn
2240-2993journal_volume
75pub_type
杂志文章abstract：:Total lateral paralysis in a case of "One and half" Fisher's syndrome accompanied by paralytic pontine exotropia is described. Oculographic investigation indicates involvement of the nucleus of the VIth cranial nerve. Paralytic pontine exotropia, may therefore be encountered where the VIth nucleus is involved. ...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1986-08-01 00:00:00
abstract：:Multiple sclerosis (MS) can cause alterations in autonomic cardiovascular functions. We aimed to investigate the correlation of disease activity and disability with heart rate variability (HRV) of cardiovascular autonomic dysfunction (CAD) demonstrated by 24-h Holter monitorization. Thirty-four patients with clinicall...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2011-06-01 00:00:00
abstract：:The objective of this study was to evaluate the tolerability and efficacy of lacosamide (LCM) in residential patients at our epilepsy centre. We assessed retrospectively 80 patients (mean age 36.2 years, range 18-63 years; 29 female) with intellectual disability (ID) and drug-resistant epilepsy using an industry-indep...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-019-01098-3
更新日期：2019-09-01 00:00:00
abstract：:Cyclosporine-A is a highly potent immunosuppressive agent for solid organ transplantation, but has many side effects including nephrotoxicity, hypertension, gum hyperplasia, hepatotoxicity, and neurotoxicity. Neurotoxicity is a less known toxic effect. The pathogenesis of this effect is unclear. However, it has been p...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2001-06-01 00:00:00
abstract：:The ictal bradycardia syndrome is an uncommon diagnosis in which bradycardia is accompanied by simultaneous epileptic discharges in the EEG. We describe a patient who was referred to the emergency ward because of syncope. Ictal semeiology and EEG-EG findings are discussed and compared with those published in the liter...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2007-03-01 00:00:00
abstract：:We present a case of partial rhombencephalosynapsis, diagnosed by magnetic resonance imaging (MRI), in fetus aged 27 gestational weeks, in a dizygotic twin pregnancy. The distinctive MRI features of this cerebellar malformation (segmental hypogenesis of the cerebellar vermis, partial fusion of the cerebellar hemispher...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2011-06-01 00:00:00
abstract：:Despite the huge health and economic burden of migraine headache, few medications have been approved for its prophylactic treatment, most of which can potentially induce serious adverse effects. Coenzyme Q10 (CoQ10) is a supplement and has shown preliminary benefits in migraine prophylaxis. We aimed to assess this eff...
journal_title：Acta neurologica Belgica
pub_type： 临床试验,杂志文章
doi：10.1007/s13760-016-0697-z
更新日期：2017-03-01 00:00:00
abstract：:The objective of the study was to investigate the associations between the degree of edema with the clinical and biochemical parameters such as serum lactate dehydrogenase (LDH), albumin (ALB) in posterior reversible encephalopathy syndrome (PRES) patients. Forty-nine patients with typical clinical symptoms and charac...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-012-0060-y
更新日期：2012-09-01 00:00:00
abstract：:A 54-year-old female patient presented acute hallucinatory psychotic episodes with irritative EEG for seven years before an initial state of complex partial mal. A single convulsive episode occurred 14 years after the beginning of the psychiatric symptoms. The intercritical EEG showed independent temporal lobe foci pr...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Although migraine is a neurological disorder known for its long, physiopathology remains unclear. The aim of this study was to investigate the levels of hematological parameters and neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), lymphocyte/monocyte ratio (LMR) and neutrophil/monocyte ratio (NMR) u...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-020-01362-x
更新日期：2020-04-28 00:00:00
abstract：:Neuropathology plays a crucial role in the phenotypic individualization of hereditary disorders affecting the central and peripheral nervous system even if molecular genetics represents the most essential step in describing the genotypes. The neuropathological description of phenotypes and genotypes can be used for re...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：
更新日期：2002-03-01 00:00:00
abstract：:Between 1973 and 1978 spontaneous lysis of obstructions in an external cerebral artery was detected in seven out of 3500 patients who suffered from symptoms of cerebrovascular failure in the territory of the internal carotid or vertebral artery. All patients underwent our routine cerebrovascular Doppler ultrasound exa...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:Headache is one of the chronic disorders that can trigger sexual dysfunction due to complex mechanisms. This study recruited 120 consecutive patients from our outpatient clinics with migraine (n = 60), TTH (n = 60) as well as healthy age-matched controls (n = 60) for a total of 180 patients. All the participants were ...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-020-01504-1
更新日期：2020-09-25 00:00:00
abstract：:Febrile seizures (FS) are recognized as an antecedent to the development of temporal lobe epilepsy with hippocampal sclerosis (TLE-HS), but it is unclear whether prolonged FS are a direct cause of TLE-HS. Here, we used a rat model of infantile FS to study the effects of inflammatory cytokines on seizure susceptibility...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-013-0246-y
更新日期：2014-09-01 00:00:00
abstract：:The etiology of chronic subdural hematoma (CSDH) in patients is diverse. The primary objective of this article was to discuss one of the causes, spontaneous intracranial hypotension with spinal cerebrospinal fluid (CSF) leak, which is usually neglected by the neurosurgeon. All the consecutive 15 patients who underwent...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-016-0597-2
更新日期：2016-12-01 00:00:00
abstract：:Recovery of stroke-related aphasia can be affected by language therapy in the early and chronic stage. Objectively monitoring therapy-induced neuroplasticity is possible by several measurement techniques including electro- and magneto-encephalography. The obtained event-related potentials (ERPs) and fields (ERFs) prov...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：10.1007/s13760-020-01378-3
更新日期：2020-08-01 00:00:00
abstract：:This review focusses on the validation and standardization of Alzheimer's disease (AD) cerebrospinal fluid (CSF) biomarkers, as well as on the current clinical indications and rational use of CSF biomarkers in daily clinical practice. The validated AD CSF biomarkers, Aβ1-42, T-tau, and P-tau181, have an added value in...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：10.1007/s13760-017-0816-5
更新日期：2017-09-01 00:00:00
abstract：:Despite intensive research efforts, the cause of the muscular dystrophies has remained elusive for many decades. In the late 1980s, major advances in molecular genetics have led to the discovery of the dystrophin gene and its protein product, dystrophin. Mutations in the dystrophin gene result in dystrophin deficiency...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：
更新日期：1995-01-01 00:00:00
abstract：:In Parkinson's disease (PD), sleep disorders (SD) occur as a result of the neurochemical changes in sleep centres, neurodegenerative changes in dopaminergic neurons, and other factors. The most common SD include excessive daytime sleepiness, insomnia, restless legs syndrome and nocturia. The aim of the study was to co...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-015-0478-0
更新日期：2015-12-01 00:00:00
abstract：:The percentage of echinocytes in the blood from patients affected by Duchenne muscular dystrophy, in mothers carriers of the dystrophic state, and in Steinert dystrophic patients, has been investigated after addition of low levels of lysolecithin. The echinocyte content was significantly higher in both Duchenne patien...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1981-07-01 00:00:00
abstract：:To evaluate the relationship between disease duration, disability, disease pattern, age and sex with fatigue in MS patients. One hundred and seventy-three clinically definite MS patients and 87 age-matched healthy controls enrolled in this cross sectional study. Demographic data (sex, age), duration of the disease and...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-013-0198-2
更新日期：2013-12-01 00:00:00
abstract：:The primary source of malignant intracerebral nerve sheath tumors is still unclear We report the imaging and MR spectroscopic findings in a 39-year-old man with a very rare brain stem tumor MR examination revealed the presence of intraaxial brain stem tumor with a partial exophytic growth. On pathological examination,...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2008-06-01 00:00:00
abstract：:The aim of this study was to investigate personality, by means of the Rorschach Psychodiagnostic test, in a consecutive series of fourteen patients with Parkinson's disease (PD) submitted to bilateral deep brain stimulation of the subthalamic nucleus (DBS STN). Patients were evaluated pre-operatively and 1 year after ...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2008-03-01 00:00:00
abstract：:After a review of current concepts about post-traumatic mutism, the authors describe five patients with this unusual symptom. The study extends on a long follow-up period. Differential diagnosis and possible neurological and psychopathological factors are discussed. Analysis of their personal observations leads the au...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1979-09-01 00:00:00
abstract：:Functional brain imaging studies, such as positron emission tomography and functional nuclear magnetic resonance imaging, are based on the regional increases in cerebral blood flow, glucose consumption and oxygen consumption that are associated with regional increases in neuronal activity. The cellular basis of the si...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：
更新日期：2002-12-01 00:00:00
abstract：:Friedreich's ataxia (FRDA), an autosomal recessive disorder, is characterized by spinocerebellar degeneration and cardiomyopathy. Here we explore some of the putative mechanisms underlying the cardiomyopathy in FRDA that have been elucidated using different experimental models. FRDA is characterized by a deficiency in...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：
更新日期：2011-09-01 00:00:00
abstract：:Blood circulating endothelial cells and circulating hematopoietic progenitor cells (CPCs) are two cell populations that are thought to play important role in angiogenesis. In the present study, we investigated the role of CPCs in patients with brain tumors. We prospectively studied 19 brain tumor patients. Ten healthy...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-012-0097-y
更新日期：2013-03-01 00:00:00
abstract：:The aim of this study was to test feasibility of transcranial Doppler (TCD) and single photon emission computed tomography (SPECT) during compound neuroactivation task. The study was performed in 60 healthy right-handed volunteers. Cerebral blood flow velocity was measured by TCD in both middle cerebral arteries (MCA)...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-012-0152-8
更新日期：2013-09-01 00:00:00
abstract：PURPOSE:total removal of spinal hemangioblastomas with satisfactory clinical outcomes remains a challenge. We aimed to evaluate the surgical outcomes of our spinal hemangioblastomas patients, summarize our experiences with this condition and review-related literature. METHODS:records of 18 spinal hemangioblastoma pati...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-020-01420-4
更新日期：2020-07-07 00:00:00
abstract：BACKGROUND:FDG-PET in ALS most typically demonstrates a primary (and sometimes also supplementary) motor cortex hypometabolism, often associated with more diffuse cortical hypometabolism involving mostly the dorsolateral prefrontal cortex, the medial and lateral premotor cortices, and the bilateral insular cortex invol...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2011-12-01 00:00:00
