Abstract：
:Functional brain imaging studies, such as positron emission tomography and functional nuclear magnetic resonance imaging, are based on the regional increases in cerebral blood flow, glucose consumption and oxygen consumption that are associated with regional increases in neuronal activity. The cellular basis of the signals that are measured is however incompletely understood at present. An increasingly important role for astrocytes in neurovascular metabolic coupling is being described, which was already suggested over 100 years ago as astrocytes are a structural link between endothelial cells of brain capillaries and neurons. Recent data have provided evidence for a role of the astrocytic intracellular sodium concentration in driving astrocytic glycolysis that may provide neurons with lactate as an energy substrate during activation. We have previously described intracellular sodium changes in astrocytes that are associated with astrocytic intercellular calcium waves. These intercellular calcium waves have been demonstrated both in astrocytes in culture as well as in brain slices. In this paper a new hypothesis concerning a role for astrocytic intercellular calcium waves in brain energy metabolism is formulated.
journal_name
Acta Neurol Belgjournal_title
Acta neurologica Belgicaauthors
Paemeleire Kkeywords:
subject
Has Abstractpub_date
2002-12-01 00:00:00pages
153-7issue
4eissn
0300-9009issn
2240-2993journal_volume
102pub_type
杂志文章,评审abstract：:The aim of this study was to test feasibility of transcranial Doppler (TCD) and single photon emission computed tomography (SPECT) during compound neuroactivation task. The study was performed in 60 healthy right-handed volunteers. Cerebral blood flow velocity was measured by TCD in both middle cerebral arteries (MCA)...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-012-0152-8
更新日期：2013-09-01 00:00:00
abstract：:The authors report the case of a 17 year-old female patient who presented acute ascending polyneuritis of the Landry-Guillain-Barré type extending to all cranial nerve pairs during the abatement of hepatitis of unspecified etiology. The patient remained in a state of coma vigil for five days prior to gradual but full ...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1980-07-01 00:00:00
abstract：:Recently, great advances have been made in the surgical treatment of intramedullary spinal cord tumors (IMSCTs). Many articles have been published; but looking at the literature of the last 5 years, there are only descriptive reviews and no works in which a literature statistical analysis was performed. Here, we analy...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：10.1007/s13760-016-0684-4
更新日期：2017-03-01 00:00:00
abstract：:Multiple sclerosis (MS) often starts in the form of clinically isolated syndrome (CIS) and only some of the CIS patients progress to relapsing-remitting MS (RRMS). Biomarkers to predict conversion from CIS to MS are thus greatly needed for making correct treatment decisions. To identify a predictive cerebrospinal flui...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-018-0954-4
更新日期：2019-03-01 00:00:00
abstract：:The authors present and illustrate most of the ultrastructural abnormalities encountered in skeletal muscle in cases of neuromuscular disease. The diagnostic significance of the changes are discussed but emphasis is laid on the nonspecific character of most of them. For diagnostic purposes, examination by light micros...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1981-03-01 00:00:00
abstract：:Biochemical, physiological and functional studies suggest that the brain renin-angiotensin system (RAS) is regulated independently of the peripheral RAS. Also, all enzymes and peptides necessary for the biosynthesis of various angiotensins have been recognized within the central nervous system. There are divergent opi...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：
更新日期：2009-09-01 00:00:00
abstract：:A correlation is made between the index of circulatory resistance given by ultrasonic flow-measurement and rheography. Patients with normal and increased blood pressure were studied. The characteristics of the transient and of the permanent ischaemic attacks are defined. ...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:Multiple sclerosis (MS) can cause alterations in autonomic cardiovascular functions. We aimed to investigate the correlation of disease activity and disability with heart rate variability (HRV) of cardiovascular autonomic dysfunction (CAD) demonstrated by 24-h Holter monitorization. Thirty-four patients with clinicall...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2011-06-01 00:00:00
abstract：:One study found higher red blood cell distribution width (RDW) on the admission of traumatic brain injury (TBI) in non-surviving patients; however, a regression analysis was not carried out to establish an association between RDW and TBI mortality. Thus, the objectives of this study were to determine whether there is ...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-020-01409-z
更新日期：2020-06-15 00:00:00
abstract：OBJECTIVE:To study the impact of cognitive impairment and severity of dementia on the quality of life (QoL) of patients and their caregivers. DESIGN:Descriptive cross-sectional study within the NAtional Dementia Economic Study. SETTING:231 general practices and 15 specialist clinics in Belgium. SUBJECTS:605 patients...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2003-03-01 00:00:00
abstract：:Multiple sclerosis is considered to be an immune mediated inflammatory disorder of the central nervous system. It mainly affects young, socioeconomic active patients. Although our armamentarium for this disease has significantly evolved in recent years some patients remain refractory to conventional therapies. In thes...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-018-0905-0
更新日期：2018-06-01 00:00:00
abstract：:Thromboelastography (TEG) is commonly used to predict coagulation state in patients with active bleeding. However, the correlation between TEG parameters and conventional tests in patients with cerebrovascular disease (CVD) remains unexplored. Here, we assessed the TEG values and their correlation with conventional te...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-020-01456-6
更新日期：2020-08-05 00:00:00
abstract：:Amyotrophic lateral sclerosis (ALS) is described as a neurodegenerative disorder. However, neuroinflammation and chemokine expression are prominent pathological finding at sites of injury. Adipsin and adiponectin are molecules that are implicated in the pathogenesis of neurodegenerative and neuroimmune disorders. Adip...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-017-0798-3
更新日期：2017-12-01 00:00:00
abstract：:Out of the various drugs which may be used in the treatment of intracramial hypertension we have tested long-acting Synacthen (Synacthen-dépot) in patients with inoperable cerebral tumours. The results were favourable, especially in the case of long-term treatment, since the delayed action of the drug allows flexible ...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1976-07-01 00:00:00
abstract：:Optical coherence tomography (OCT) has been suggested as a method for detection of retinal alterations in neurodegenerative diseases. The usefulness of OCT as a diagnostic tool to differentiate Parkinson's disease (PD) from other tremor diseases, remains unknown. We aimed to evaluate morphological changes of the retin...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-019-01228-x
更新日期：2020-02-01 00:00:00
abstract：:Celiac disease (CD) and non celiac gluten sensitivity (NCGS) can be responsible for neurological complications such as ataxia and peripheral neuropathies but also cognitive impairment. This cognitive involvement is variable in its expression, its duration and its prognosis ranging from transient and reversible subtle ...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：10.1007/s13760-017-0870-z
更新日期：2018-03-01 00:00:00
abstract：:To evaluate the value of pupil cycle time (PCT) as an indicator of optic nerve dysfunction in patients with multiple sclerosis (MS), 42 patients with MS and 35 control subjects were included to the study. Patients with MS with a history of ON were accepted as group 1, without a history of ON as group 2 and healthy con...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-016-0740-0
更新日期：2017-03-01 00:00:00
abstract：:Although cerebral palsy (CP), which affects the quality of life of many children and their families, is the most common cause of motor dysfunction in children, no comprehensive bibliometric study has holistically evaluated the publications on CP. This study aimed to analyze the scientific outputs published on CP in pe...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-020-01549-2
更新日期：2020-11-23 00:00:00
abstract：:A case of Refsum's disease in a 62-year-old man, with an ophthalmologic symptomatology dominated by a tight bilateral miosis, is reported. The miosis mechanism in this disease is discussed. The clinical evolution has been stabilized by a diet poor in phytanic acid. ...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：:The most common causes of chronic cough in nonsmokers are postnasal drip syndrome, asthma, and gastroesophageal reflux disease. Drugs are also important in the etiology of resistant cough. Most common drugs inducing cough are the ACE inhibitors. Many drugs other than ACE inhibitors can also cause dry cough and one amo...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-012-0016-2
更新日期：2012-06-01 00:00:00
abstract：:In Parkinson's disease (PD), sleep disorders (SD) occur as a result of the neurochemical changes in sleep centres, neurodegenerative changes in dopaminergic neurons, and other factors. The most common SD include excessive daytime sleepiness, insomnia, restless legs syndrome and nocturia. The aim of the study was to co...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-015-0478-0
更新日期：2015-12-01 00:00:00
abstract：:Estradiol (E2) has been used in the treatment of Alzheimer's disease (AD) for many years but with various responses. Evidence from clinical studies, randomized clinical trials (RCTs), and observational studies further underscores the importance of E2 in postmenopause women diagnosed with AD. The purpose of this articl...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：10.1007/s13760-015-0593-y
更新日期：2016-09-01 00:00:00
abstract：: ...
journal_title：Acta neurologica Belgica
pub_type： 信件
doi：10.1007/s13760-018-0897-9
更新日期：2018-12-01 00:00:00
abstract：:The various neurological manifestations encountered in 40 zairians out of a total of 500 with homozygous (SS) Sickle cell disease were described. These included convulsions, vascular accidents, mental changes, increased intracranial pressure and meningism. The literature on the involvement of the nervous system in Sic...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1977-03-01 00:00:00
abstract：:Epilepsy affects 50 million patients and their caregivers worldwide. Devices that facilitate the detection of seizures can have a large influence on a patient's quality of life, therapeutic decisions and the conduct of clinical trials with anti-epileptic drugs. This article provides an up-to-date overview and comparis...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：10.1007/s13760-020-01417-z
更新日期：2020-12-01 00:00:00
abstract：:Neurosarcoidosis is a diagnostic challenge, especially in the absence of systemic involvement, even when cerebral biopsies show noncaseating granulomas. We report a patient with a pineal germinoma associated with a extensive peri- and intra- tumoural granulomatous reaction, who was first diagnosed as possible neurosar...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2009-06-01 00:00:00
abstract：:The first applications of positron emission tomography (PET) for the study of brain tumours appeared early in the development of this technology. New trends in these particular PET applications tend to take into account the histological heterogeneity of these tumours and the necessity to integrate PET data in their su...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：
更新日期：1997-09-01 00:00:00
abstract：:Oculomotor functions are analysed by clinical examination and oculography in 21 cases of deep cerebral hematoma. Significant paralysis of verticality and of movements contralateral to the lesions was observed in all cases where the hemorrhage affected the paramedian thalamo-subthalamic region. A slight deficit of elev...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1983-11-01 00:00:00
abstract：:We present a case of partial rhombencephalosynapsis, diagnosed by magnetic resonance imaging (MRI), in fetus aged 27 gestational weeks, in a dizygotic twin pregnancy. The distinctive MRI features of this cerebellar malformation (segmental hypogenesis of the cerebellar vermis, partial fusion of the cerebellar hemispher...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2011-06-01 00:00:00
abstract：:The concept of a group of headaches whose pathophysiological focus revolves around the trigeminal-autonomic reflex fills a useful gap in characterising a number of primary headache syndromes. Broadly, these syndromes involve activation of trigeminovascular nociceptive pathways with reflex cranial autonomic activation....
journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：
更新日期：2001-03-01 00:00:00
