Abstract：
OBJECTIVE:To study the impact of cognitive impairment and severity of dementia on the quality of life (QoL) of patients and their caregivers. DESIGN:Descriptive cross-sectional study within the NAtional Dementia Economic Study. SETTING:231 general practices and 15 specialist clinics in Belgium. SUBJECTS:605 patients aged > or = 65 years: 106 referent subjects without cognitive impairment (R), 113 subjects with cognitive impairment and no dementia (CIND), 386 subjects with mild (83), mild/moderate (108), moderate (62) or severe (133) dementia (D1 to D4). OUTCOME MEASURES:QoL of patients: COOP/WONCA charts, Katz's Activities of Daily Living (ADL) scale, Lawton's Instrumental Activities of Daily Living (IADL) scale. QoL of caregivers: COOP/WONCA charts, SF-36 questionnaire, short-form Beck Depression Inventory, Sense of Competence questionnaire (SCQ). MAIN RESULTS:QoL of patients: For R, CIND and D1 to D4 patients, dependence for ADL reached 5%, 6%, 16%, 20%, 48% and 79%, respectively, and mean IADL scores were 5.6, 5.0, 3.4, 2.0, 0.6 and 0.1, respectively. QoL of caregivers: The main impact of caregiving was on mental health, with SF-36 MCS scores of 51.3, 47.7 and 45.4 for R, CIND and all D patients and respectively 32.6%, 31.3% and 42.5% depression prevalence. Sense of competence decreased with severity of patient's cognitive impairment. Caregivers of CIND patients always rated intermediate between R and D1 patients. Caregivers of D3 patients were the most affected ones. CONCLUSION:The data suggest that improving the cognitive status of patients and providing assistance to caregivers would be complementary ways of action to support caregiving of patients living at home.
journal_name
Acta Neurol Belgjournal_title
Acta neurologica Belgicaauthors
Kurz X,Scuvee-Moreau J,Vernooij-Dassen M,Dresse Akeywords:
subject
Has Abstractpub_date
2003-03-01 00:00:00pages
24-34issue
1eissn
0300-9009issn
2240-2993journal_volume
103pub_type
杂志文章abstract：:The authors report a case of ataxic hemiparesis (dysarthria-clumsy hand syndrome plus crural hemiparesis with homolateral ataxia), secondary to a single cerebellar lacuna (CT scan), in a left rostral para-vermian position in the vicinity of the peduncle and secondary to arterial hypertension. They discuss the nosologi...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：
更新日期：1989-03-01 00:00:00
abstract：:Down syndrome (DS) is a genetic disorder associated with mental and motor developmental delays in childhood. The aim of this study was to investigate the relationship of the femoral cartilage thickness with motor performance in children with Down syndrome (DS). A total of 39 children with DS in the age range of 12-42 ...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-019-01105-7
更新日期：2019-03-06 00:00:00
abstract：:Eighteen patients (11 male, 7 female) with left thalamic haemorrhage confirmed by CT-scan of the brain were investigated for their language function. Aphasia Test for Turkish Citizens modified from Mayo Clinic Aphasia Test and Boston Diagnostic Aphasia Examination were given for evaluating the language modalities. Flu...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:A 40 year-old woman with subacute headache and visual impairment was admitted. Neurological examination revealed meningismus, diminished visual acuity, bilateral sixth cranial nerve palsy, and papillary edema. Dermatologic examination was normal. The brain CT scan showed hydrocephalus and hyperdense edging around fiss...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2011-09-01 00:00:00
abstract：:On the basis of 90 cerebral AVMs, the authors study clinical signs which show the AVM, before a dramatic bleeding. Such clinical signs are: benign subarachnoid hemorrhage or intracranial hypertension and, only for lobar AVMs, migraine, epileptic seizures, progressive neurological deficit. In such cases a misdiagnosis ...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1985-03-01 00:00:00
abstract：:The authors present and illustrate most of the ultrastructural abnormalities encountered in skeletal muscle in cases of neuromuscular disease. The diagnostic significance of the changes are discussed but emphasis is laid on the nonspecific character of most of them. For diagnostic purposes, examination by light micros...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1981-03-01 00:00:00
abstract：:There is a need for new methods to study CSF proteins. Kerenyi et al., 1973 and Verheecke, 1975 have already used this method and discussed its advantages. The electrophoresis is carried out according to the method of Wieme with as supporting medium agar. The volume applied varies between 5 to 15 microliters according...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1979-07-01 00:00:00
abstract：:Chorea paralytica (or chorea mollis) is a very rare variant of Sydenham's chorea, characterized by a profound hypotonia, resulting in severe disability. Given the rarity of this condition, data on its prognosis are lacking. Most reports suggest that the delay from onset to recover total autonomy is long, usually sever...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-013-0214-6
更新日期：2013-12-01 00:00:00
abstract：:BRAT1-related neurodevelopmental disorders are characterized by heterogeneous phenotypes with varying levels of clinical severity. Since the discovery of BRAT1 variants as the molecular etiology of lethal neonatal rigidity and multifocal seizure syndrome (RMFSL, OMIM 614498), these variants have also been identified i...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-020-01513-0
更新日期：2020-12-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：10.1007/s13760-018-1044-3
更新日期：2019-03-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：10.1007/s13760-020-01295-5
更新日期：2020-04-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2004-06-01 00:00:00
abstract：:A case of femoral palsy associated with chronic pain sensible to Carbamazepine, secondary to iliacus haematoma during anticoagulant therapy is reported. Late femoral nerve decompression followed by transcutaneous neurostimulation permit the normalization of the sensory nerve conduction and a complete clinical recovery...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1985-11-01 00:00:00
abstract：:For a long-term period (25-30 years) the author sums up the results obtained by cervical discectomy through a ventral route followed by interbody arthrodisis. In the disc diseases, the radicular syndromes gave excellent results, the medullar syndromes good results. In the cervical injuries, the results were always goo...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1987-03-01 00:00:00
abstract：:The purpose of the study was to evaluate the relationship between sympathetic skin responses (SSR), electrodiagnostic reflex activities (F wave, H reflex), and functional capacity in post-stroke patients. The study comprised 40 hemiplegia patients (mean age 57.8 ± 10.9 years) and 40 healthy volunteers (mean age 557 ± ...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-014-0397-5
更新日期：2015-09-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：
更新日期：1997-09-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Guillain-Barré Syndrome (GBS) is best viewed as a clinical syndrome which can have at least two clinical substrates: the commonest is an acquired demyelinating polyradiculoneuropathy and the other is an acute motor axonal neuropathy. An acute acquired neuropathy can also sometimes cause the Miller Fisher syndrome of o...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
abstract：:Despite the huge health and economic burden of migraine headache, few medications have been approved for its prophylactic treatment, most of which can potentially induce serious adverse effects. Coenzyme Q10 (CoQ10) is a supplement and has shown preliminary benefits in migraine prophylaxis. We aimed to assess this eff...
journal_title：Acta neurologica Belgica
pub_type： 临床试验,杂志文章
doi：10.1007/s13760-016-0697-z
更新日期：2017-03-01 00:00:00
abstract：:Recovery of stroke-related aphasia can be affected by language therapy in the early and chronic stage. Objectively monitoring therapy-induced neuroplasticity is possible by several measurement techniques including electro- and magneto-encephalography. The obtained event-related potentials (ERPs) and fields (ERFs) prov...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：10.1007/s13760-020-01378-3
更新日期：2020-08-01 00:00:00
abstract：: ...
journal_title：Acta neurologica Belgica
pub_type： 信件
doi：10.1007/s13760-018-0897-9
更新日期：2018-12-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-012-0152-8
更新日期：2013-09-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2004-03-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：
更新日期：1995-01-01 00:00:00
abstract：:Increasing costs of healthcare call for rational approaches based on cost-effectiveness of the surgical procedures. When treating trigeminal neuralgia, therapeutic options vary widely as does their cost. We have compared microvascular decompression (MVD), radiofrequency rhizotomy (RFR), percutaneous balloon compressio...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-012-0095-0
更新日期：2012-09-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2002-06-01 00:00:00
abstract：:High resolution MRI is very important in the evaluations of patients with intractable temporal lobe epilepsy in preoperative investigations. Morphologic abnormalities on cranial MRI usually indicate the epileptogenic focus. Intractable TLE patients who have normal cranial MRI or bilateral hippocampal atrophy may have ...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2006-03-01 00:00:00
abstract：:Between January 1992 and June 1995, 160 patients were presurgically evaluated for medically refractory epilepsy by the Epilepsy Monitoring and Surgery Team at the University Hospital of Gent. All these patients underwent a comprehensive presurgical evaluation, including extensive neurological history and examination, ...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1996-03-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：
更新日期：2010-03-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-015-0431-2
更新日期：2015-12-01 00:00:00
