Abstract:
:High resolution MRI is very important in the evaluations of patients with intractable temporal lobe epilepsy in preoperative investigations. Morphologic abnormalities on cranial MRI usually indicate the epileptogenic focus. Intractable TLE patients who have normal cranial MRI or bilateral hippocampal atrophy may have a chance for surgery if a certain epileptogenic focus is determined. We evaluated the patients who were monitorized in Gazi University Medical Faculty Epilepsy Center from October 1997 to April 2004. Seventy three patients, who had a temporal epileptogenic focus, underwent anterior temporal lobectomy at Ankara University Medical Faculty Department of Neurosurgery. Twelve of them (16, 4%), did not have any localizing structural lesion on cranial MRI. Of the 12 patients examined 6 had normal findings and 6 had bilateral hippocampal atrophy. Of these 12 patients, 6 (50%) were women and 6 (50%) were men. The ages of patients ranged from 7 to 37 (mean: 24.5). Preoperatively long-term scalp video-EEG monitoring, cranial MRI, neuropsychological tests, and Wada test were applied in all patients. Five patients, whose investigations resulted in conflicting data, underwent invasive monitoring by the use of subdural strips. The seizure outcome of patients were classified according to Engel with postsurgical follow-up ranging from 11 to 52 (median: 35.7) months. Nine patients (75%) were classified into Engel's Class I and the other 3 patients (25%) were placed into Engel's Class II. One patient who was classified into Engel's Class II had additional psychiatric problems. The other patient had two different epileptogenic foci independent from each other in her ictal EEG. One of them localized in the right anterior temporal area, the other was in the right frontal lobe. She was classified in Engel's Class II and had no seizure originating from temporal epileptic focus, but few seizures originating from the frontal region continued after the surgery. In conclusion, surgery was successful in all 12 patients. We think that patients with no MRI lateralizing or localizing lesion should undergo epilepsy surgery after detailed presurgical evaluations, including invasive monitoring.
journal_name
Acta Neurol Belgjournal_title
Acta neurologica Belgicaauthors
Gomceli YB,Erdem A,Bilir E,Kutlu G,Kurt S,Erden E,Karatas A,Erbas C,Serdaroglu Asubject
Has Abstractpub_date
2006-03-01 00:00:00pages
9-14issue
1eissn
0300-9009issn
2240-2993journal_volume
106pub_type
杂志文章abstract::Diffuse multicentric sarcomas of the brain, also called cerebral malignant lymphomas, sometimes present symmetrical topography. This is well demonstrated by a CAT mirror image obtained by the authors in the reported case. The diagnostic value of the image is underlined in view of the possible forms of therapy, in part...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1980-03-01 00:00:00
abstract::We investigated the ophthalmologic manifestations and factors that influence outcomes in patients with myasthenia gravis (MG). We retrospectively analyzed the prevalence of neuro-ophthalmologic findings and clinical and outcome measures of 100 consecutive patients (53 males, 47 females), aged 55.7 ± 17.5 (range 15-85)...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01556-3
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abstract::Sleep and sleep deprivation are often used for EEG activation in epilepsy. We compared postprandial naps and day-long sleep deprived EEGs in 36 patients with generalized seizures, 57 complex partial seizure patients, and 7 individuals with mixed seizure disorders. Ten of 36 generalized seizure patients had normal slee...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:1990-01-01 00:00:00
abstract::Cerebral venous sinus thrombosis is an uncommon cause of stroke, which is more prevalent in Iran and the Middle East. We aimed to assess the etiology, radiologic, and clinical manifestations of cerebral venous sinus thrombosis, specifically the predictors of patients' outcome in Namazi hospital, Shiraz, Iran. In this ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-018-1009-6
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abstract::There have been recent reports of antibody-mediated status epilepticus. The objective of our study was to investigate the prevalence of neuronal autoantibodies in patients with status epilepticus (SE) with unresolved etiology. The presence of neuronal autoantibodies was investigated prospectively in adult patients wit...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-017-0796-5
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract::Imaging neurotransmission in vivo using positron emission tomography (PET) is a rapidly expanding clinical science. The present review summarizes the actual contribution of PET imaging to clinical problems in movement and seizure disorders and dementia. ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:2005-09-01 00:00:00
abstract::Between January 1992 and June 1995, 160 patients were presurgically evaluated for medically refractory epilepsy by the Epilepsy Monitoring and Surgery Team at the University Hospital of Gent. All these patients underwent a comprehensive presurgical evaluation, including extensive neurological history and examination, ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract::Epilepsy is a neurological disorder consisting of recurrent seizures, resulting from excessive, uncontrolled electrical activity in the brain. Epilepsy treatment is successful in the majority of the cases; however; still one third of the epilepsy patients are refractory to treatment. Besides the ongoing research on th...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:2006-06-01 00:00:00
abstract::Friedreich's ataxia (FRDA), an autosomal recessive disorder, is characterized by spinocerebellar degeneration and cardiomyopathy. Here we explore some of the putative mechanisms underlying the cardiomyopathy in FRDA that have been elucidated using different experimental models. FRDA is characterized by a deficiency in...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:2011-09-01 00:00:00
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-018-0993-x
更新日期:2019-03-01 00:00:00
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-018-0945-5
更新日期:2018-12-01 00:00:00
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:10.1007/s13760-013-0270-y
更新日期:2014-06-01 00:00:00
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journal_title:Acta neurologica Belgica
pub_type: 临床试验,杂志文章
doi:10.1007/s13760-014-0395-7
更新日期:2015-09-01 00:00:00
abstract::Cisplatin is an anticancer agent widely used in the treatment of malignant tumors. One of the major adverse effects of cisplatin is its neurotoxicity. Memantine, an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, has been reported to have neuroprotective effects against neurological deficits. This study...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-019-01161-z
更新日期:2020-02-01 00:00:00
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-019-01182-8
更新日期:2020-04-01 00:00:00
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01362-x
更新日期:2020-04-28 00:00:00
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-015-0431-2
更新日期:2015-12-01 00:00:00
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2009-03-01 00:00:00
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:10.1007/s13760-013-0264-9
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-017-0868-6
更新日期:2018-03-01 00:00:00
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
abstract::The first applications of positron emission tomography (PET) for the study of brain tumours appeared early in the development of this technology. New trends in these particular PET applications tend to take into account the histological heterogeneity of these tumours and the necessity to integrate PET data in their su...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:1997-09-01 00:00:00
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-014-0331-x
更新日期:2015-06-01 00:00:00
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:10.1007/s13760-020-01378-3
更新日期:2020-08-01 00:00:00
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:10.1007/s13760-020-01295-5
更新日期:2020-04-01 00:00:00
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1984-08-01 00:00:00
abstract::Out of the various drugs which may be used in the treatment of intracramial hypertension we have tested long-acting Synacthen (Synacthen-dépot) in patients with inoperable cerebral tumours. The results were favourable, especially in the case of long-term treatment, since the delayed action of the drug allows flexible ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1976-07-01 00:00:00