Abstract:
:To evaluate the value of pupil cycle time (PCT) as an indicator of optic nerve dysfunction in patients with multiple sclerosis (MS), 42 patients with MS and 35 control subjects were included to the study. Patients with MS with a history of ON were accepted as group 1, without a history of ON as group 2 and healthy control subjects as group 3. Groups were compared with Chi-square and one-way ANOVA tests. Correlations of PCT results with age, best corrected visual acuity, duration of MS, visual field (VF) test, visual evoked potential (VEP) latans, retinal nerve fiber layer (RNFL), and ganglion cell layer-inner plexiform layer (GCL-IPL) thicknesses were analyzed. Mean PCT was 1286.4 ± 357.8 ms in group 1, 1021.3 ± 102.3 ms in group 2, and 872.5 ± 69.4 ms in group 3 (p < 0.001). Moderate-to-significant correlations were found between PCT measurements and duration of MS, VF test, VEP latans, RNFL, and GCL-IPL thicknesses. PCT might be an alternative method to evaluate the optic nerve function in patients with MS.
journal_name
Acta Neurol Belgjournal_title
Acta neurologica Belgicaauthors
Karahan E,Karti O,Koskderelioglu A,Karti DT,Uyar M,Kale MY,Gedizlioglu Mdoi
10.1007/s13760-016-0740-0subject
Has Abstractpub_date
2017-03-01 00:00:00pages
75-81issue
1eissn
0300-9009issn
2240-2993pii
10.1007/s13760-016-0740-0journal_volume
117pub_type
杂志文章abstract::Osmotic demyelination syndrome (ODS) is the damage over the central nervous system caused by several electrolytes, metabolic and toxic disorders. We aimed to describe cases of unusual forms of ODS. In a 9-year period, 25 consecutive patients with ODS (15 men; mean age 42 years) were registered in our referral institut...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-012-0110-5
更新日期:2013-03-01 00:00:00
abstract::A 54-year-old female patient presented acute hallucinatory psychotic episodes with irritative EEG for seven years before an initial state of complex partial mal. A single convulsive episode occurred 14 years after the beginning of the psychiatric symptoms. The intercritical EEG showed independent temporal lobe foci pr...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::We report the case of a 44-year-old woman with chronic facial pain. She was treated with several analgesics, prophylactic medications and infiltrations, but all treatment modalities were ineffective. Finally, the diagnosis of medication-overuse headache complicating migraine without aura was made and an appropriate tr...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2009-09-01 00:00:00
abstract::Epilepsy and psychiatric diseases are frequent comorbidities. Psychoses in patients with epilepsy have special physiopathology and several clinical presentations and prognoses. Their treatments are also specific, according to the specific diagnosis. This paper represents the summary of a consensus meeting held in Nove...
journal_title:Acta neurologica Belgica
pub_type: 共识发展会议,杂志文章,评审
doi:
更新日期:2005-03-01 00:00:00
abstract::As dystonia may represent a severe disease with possible fatal outcome or physical or social incapacity, and considering the limited efficacy of drug treatments (excepted doparesponsive dystonia), efforts have been made since the 1950s to propose alternative treatment. In this paper, an overview of the works done by n...
journal_title:Acta neurologica Belgica
pub_type: 传,历史文章,杂志文章
doi:
更新日期:2003-09-01 00:00:00
abstract::Multiple sclerosis (MS) often starts in the form of clinically isolated syndrome (CIS) and only some of the CIS patients progress to relapsing-remitting MS (RRMS). Biomarkers to predict conversion from CIS to MS are thus greatly needed for making correct treatment decisions. To identify a predictive cerebrospinal flui...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-018-0954-4
更新日期:2019-03-01 00:00:00
abstract::This study investigates symptom relief in patients whose hemifacial spasms (HFS) were completely relieved following microvascular decompression (MVD). Patients with HFS who were operated on from January 2007 to May 2011, at our department, were studied. The medical records and operation videos of each patient were rev...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-015-0471-7
更新日期:2016-03-01 00:00:00
abstract:: ...
journal_title:Acta neurologica Belgica
pub_type: 信件
doi:10.1007/s13760-017-0846-z
更新日期:2019-03-01 00:00:00
abstract::Over the last decade, many new drugs have been added to the therapeutic armamentarium for epilepsy. These drugs differ considerably in their mechanisms of action and, consequently, in their spectrum of efficacy against various seizure types. Oxcarbazepine, gabapentin, tiagabine and vigabatrin are especially useful in ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:1999-12-01 00:00:00
abstract::The purpose of the study was to evaluate the relationship between sympathetic skin responses (SSR), electrodiagnostic reflex activities (F wave, H reflex), and functional capacity in post-stroke patients. The study comprised 40 hemiplegia patients (mean age 57.8 ± 10.9 years) and 40 healthy volunteers (mean age 557 ± ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-014-0397-5
更新日期:2015-09-01 00:00:00
abstract::Although cerebral palsy (CP), which affects the quality of life of many children and their families, is the most common cause of motor dysfunction in children, no comprehensive bibliometric study has holistically evaluated the publications on CP. This study aimed to analyze the scientific outputs published on CP in pe...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01549-2
更新日期:2020-11-23 00:00:00
abstract::Neuromyelitis optica spectrum disorder (NMOSD) has unknown risk factors. The aim of this study was to identify the environmental risk factors for NMOSD. A case-control study was conducted in Tehran from 2015 to 2016 among 100 patients with NMOSD. Sex-matched healthy controls (n = 400) were selected through random digi...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-018-0900-5
更新日期:2018-06-01 00:00:00
abstract::The objective of this study was to evaluate the tolerability and efficacy of lacosamide (LCM) in residential patients at our epilepsy centre. We assessed retrospectively 80 patients (mean age 36.2 years, range 18-63 years; 29 female) with intellectual disability (ID) and drug-resistant epilepsy using an industry-indep...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-019-01098-3
更新日期:2019-09-01 00:00:00
abstract::We performed a retrospective study of 62 patients with syringomyelia. Most noteworthy among the clinical features in our patient population are the following: segmental sensory disturbances are usually less restrictive than the classical thermoanalgesia, pain is a presenting symptom in almost 50% of cases, and skeleta...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Oculomotor functions are analysed by clinical examination and oculography in 21 cases of deep cerebral hematoma. Significant paralysis of verticality and of movements contralateral to the lesions was observed in all cases where the hemorrhage affected the paramedian thalamo-subthalamic region. A slight deficit of elev...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1983-11-01 00:00:00
abstract::Spinal cord stimulation is an accepted treatment for neuropathic pain. Technical advances in electrode design and better patient selection have led to better and sustained pain control by these devices. Multilead electrical stimulation is the latest innovation in implantable electrostimulation (Mattrix, Medtronic Minn...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1998-06-01 00:00:00
abstract:PURPOSE:A retrospective evaluation of the ictal temporal tracer uptake and the perfusion pattern in other neo- and subcortical structures was performed to define typical extratemporal changes of rCBF that might further aid the differentiation of temporal and extratemporal seizures. METHOD:Ictal and interictal rCBF bra...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1998-12-01 00:00:00
abstract::The association of carotid atherosclerosis with silent brain infarcts (SBIs) and white matter lesions (WMLs) currently remains unknown. This study aims to compare SBIs, deep white matter lesions (DWMLs), and periventricular white matter lesions (PWMLs) in ipsilateral and contralateral hemispheres to internal carotid a...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01517-w
更新日期:2020-10-09 00:00:00
abstract::A 68 year-old man developed progressive hemidystonia and chorea 8 months after a contralateral thalamic stroke. The neurological examination also showed a right pyramidal syndrome without hemiparesis, a right horizontal sectoranopia, and a right hemihypesthesia for all sensory modalities. The MRI revealed infarctions ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract::This review focusses on the validation and standardization of Alzheimer's disease (AD) cerebrospinal fluid (CSF) biomarkers, as well as on the current clinical indications and rational use of CSF biomarkers in daily clinical practice. The validated AD CSF biomarkers, Aβ1-42, T-tau, and P-tau181, have an added value in...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:10.1007/s13760-017-0816-5
更新日期:2017-09-01 00:00:00
abstract::A case of bilateral agraphia produced by a left parietal glioma is described in a 49 year-old right-handed woman. Hypothesis of a pure agraphia, etiology and non-frontal localisation of tumor are discussed. This agraphia is associated to a right astereognosia; neither functional nor behavioral relationships are found ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1978-07-01 00:00:00
abstract::There is a need for new methods to study CSF proteins. Kerenyi et al., 1973 and Verheecke, 1975 have already used this method and discussed its advantages. The electrophoresis is carried out according to the method of Wieme with as supporting medium agar. The volume applied varies between 5 to 15 microliters according...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1979-07-01 00:00:00
abstract::Diffuse multicentric sarcomas of the brain, also called cerebral malignant lymphomas, sometimes present symmetrical topography. This is well demonstrated by a CAT mirror image obtained by the authors in the reported case. The diagnostic value of the image is underlined in view of the possible forms of therapy, in part...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1980-03-01 00:00:00
abstract::To analyze the clinical characteristics and PRRT2 gene mutation of self-limited familial infantile epilepsy and evaluate the treatment responses of different antiepileptic drugs in self-limited familial infantile epilepsy. We reviewed the clinical feature and genetic mutation results and treatment responses of two sib...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01348-9
更新日期:2020-08-01 00:00:00
abstract::Data examining the association between vitamin D and diabetic peripheral neuropathy are limited. This study investigated the serum levels of vitamin D, vitamin D-binding protein (VDBP), and vitamin D receptor (VDR) in diabetics in the Yozgat region of Turkey, and assessed their relationships with diabetic peripheral n...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-014-0304-0
更新日期:2015-03-01 00:00:00
abstract::Amyotrophic lateral sclerosis (ALS) is associated with frontotemporal lobar degeneration (FTLD) in 15% of the cases. A neuropathological continuity between ALS and FTLD-TDP is suspected. The present post-mortem 7.0-tesla magnetic resonance imaging (MRI) study compares the topographic distribution of iron (Fe) depositi...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-017-0832-5
更新日期:2017-12-01 00:00:00
abstract::A language test protocol for aphasia in French-speaking patients was drawn up recently by workers in Toulouse and Montreal. The protocol has been applied to sixty hospitalized sciatica patients of the same age range and socio-cultural level as the average population of aphasics in our department. Only one of the norma...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::Multiple sclerosis (MS) is a neuro-immunological demyelinating disease. From the immunological aspects, it is well accepted that T cells play a pivotal role in the etiology of the disease. T helper (Th) 1 and Th17 cells are thought to be the main pathogenic T cells in the pathogenesis of MS and are known as effector T...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,meta分析
doi:10.1007/s13760-018-1028-3
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:FDG-PET in ALS most typically demonstrates a primary (and sometimes also supplementary) motor cortex hypometabolism, often associated with more diffuse cortical hypometabolism involving mostly the dorsolateral prefrontal cortex, the medial and lateral premotor cortices, and the bilateral insular cortex invol...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
abstract::Epilepsy affects 50 million patients and their caregivers worldwide. Devices that facilitate the detection of seizures can have a large influence on a patient's quality of life, therapeutic decisions and the conduct of clinical trials with anti-epileptic drugs. This article provides an up-to-date overview and comparis...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:10.1007/s13760-020-01417-z
更新日期:2020-12-01 00:00:00