当前位置： SCI文献检索 > ACTA NEUROLOGICA BELGICA期刊下所有文献 > Clinical and radiological characteristics and predictors of outcome of cerebral venous sinus thrombosis, a hospital-based study.

Clinical and radiological characteristics and predictors of outcome of cerebral venous sinus thrombosis, a hospital-based study.

Abstract：

:Cerebral venous sinus thrombosis is an uncommon cause of stroke, which is more prevalent in Iran and the Middle East. We aimed to assess the etiology, radiologic, and clinical manifestations of cerebral venous sinus thrombosis, specifically the predictors of patients' outcome in Namazi hospital, Shiraz, Iran. In this retrospective study, we included all adult patients with the diagnosis of cerebral venous sinus thrombosis, who were admitted in hospital, from 2012 to 2016. Demographic data, radiologic findings, clinical presentation, risk factors, treatment, and outcome according to modified Rankin Scale (mRS) on discharge were assessed and the factors associated with hospital fatality and poor outcome (mRS > 2) were investigated through univariable and multivariable analyses. Adjusted odds ratio (OR), 95% confidence interval (CI), and p values were reported. Among 174 patients, 128 (73.6%) were female. The mean age was 37.8 ± 11.2. Total of 39 patients (22.4%) had poor discharge outcome and nine patients died in hospital. Older age (OR = 1.041, CI = 1.000-1.08), decreased level of consciousness (OR = 5.46, CI = 2.17-13.72), focal neurologic deficit (OR = 5.63, CI = 2.14-14.77), and expansion of intracranial hemorrhage (ICH) (OR = 9.13, CI = 1.96-42.64) were predictors of poor outcome according to the logistic regression model. Older age (p = 0.02), focal neurologic deficit (p = 0.005), deep venous system thrombosis (p = 0.002), early intracranial hemorrhage (p = 0.049), delayed hemorrhage (p = 0.007) and hemorrhage expansion (p = 0.002), infratentorial hemorrhagic lesions (p = 0.005), and higher CRP (p = 0.011) were associated with hospital fatality. The patients with gynecologic risk factors were at lower risk of hospital death (p = 0.005). Age, decreased consciousness and focal neurological deficit on admission, and expanded intracranial hemorrhage are predictors of poor outcome. The patients who are at higher risk of unfavorable outcome should be recognized and closely monitored.

journal_name

Acta Neurol Belg

journal_title

Acta neurologica Belgica

authors

Shakibajahromi B,Haghighi AB,Salehi A,Vardanjani HM,Ghaedian M,Safari A,Mowla A

doi

10.1007/s13760-018-1009-6

subject

Has Abstract

pub_date

2020-08-01 00:00:00

pages

845-852

issue

eissn

0300-9009

issn

2240-2993

pii

10.1007/s13760-018-1009-6

journal_volume

120

pub_type

杂志文章

在线工具

Clinical and radiological characteristics and predictors of outcome of cerebral venous sinus thrombosis, a hospital-based study.