Abstract：
AIM:The aim of this study was to determine the correlations among hippocampal damage, spontaneous recurrent seizures (SRS), and mossy fiber sprouting (MFS) using pentylenetetrazole (PTZ) kindling model. METHODS:Chronic epileptic model was established by administration of PTZ. Behaviour and EEG seizure activity were recorded. Rats' hippocampus were analyzed with haematoxylin and eosin (H&E) stain for histological lesions and evaluated for MFS with Timm stain. RESULTS:Prominent MFS was observed in area CA3 rather than the inner molecular layer in PTZ treated rats and the degree of MFS progressed with the development of behavioral kindled seizures. MFS preceded the occurrence of spontaneous seizures. No obvious neuronal necrosis and loss were observed in different regions of the hippocampus during kindling progression. CONCLUSION:MFS is not the outcome of SRS. Severe hippocampal damage is not required in the development of MFS and SRS.
journal_name
Acta Neurol Belgjournal_title
Acta neurologica Belgicaauthors
Tian FF,Zeng C,Guo TH,Chen Y,Chen JM,Ma YF,Fang J,Cai XF,Li FR,Wang XH,Huang WJ,Fu JJ,Dang Jsubject
Has Abstractpub_date
2009-12-01 00:00:00pages
298-304issue
4eissn
0300-9009issn
2240-2993journal_volume
109pub_type
杂志文章abstract：:Evaluation of the analgesic effect after a single application of the capsaicin 8 % cutaneous patch (Qutenza™) in 37 patients suffering from painful, distal symmetric polyneuropathy (PNP) for an average of 5 years. Patients ranged from 40 to 78 years of age and 22 subjects were HIV-positive. Patients were observed 4 we...
journal_title：Acta neurologica Belgica
pub_type： 临床试验,杂志文章
doi：10.1007/s13760-014-0395-7
更新日期：2015-09-01 00:00:00
abstract：:Blood circulating endothelial cells and circulating hematopoietic progenitor cells (CPCs) are two cell populations that are thought to play important role in angiogenesis. In the present study, we investigated the role of CPCs in patients with brain tumors. We prospectively studied 19 brain tumor patients. Ten healthy...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-012-0097-y
更新日期：2013-03-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：10.1007/s13760-015-0593-y
更新日期：2016-09-01 00:00:00
abstract：:Transient ischemic attack (TIA) is defined as a brief episode of neurological dysfunction caused by focal cerebral ischemia. TIA is a critical early warning signal of stroke. Patients with TIA may have long-term cognitive decline. The pathogenesis and pathological changes of TIA have not been fully elucidated. Animal ...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：10.1007/s13760-020-01295-5
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abstract：:Neuropraxia of the cervical spinal cord is a rare condition which is almost exclusively reported in American football players following cervical hyperextension or hyperflexion trauma. In this entity-neurological symptoms of both arms and legs for a period of up to 15 minutes are observed with complete recovery. We rep...
journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1983-08-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-020-01556-3
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：10.1007/s13760-012-0040-2
更新日期：2012-03-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-012-0150-x
更新日期：2013-06-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2002-09-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-017-0868-6
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-020-01549-2
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-017-0796-5
更新日期：2017-12-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1976-07-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-012-0110-5
更新日期：2013-03-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-013-0214-6
更新日期：2013-12-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：
更新日期：2010-03-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1975-09-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-017-0817-4
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-020-01365-8
更新日期：2020-05-06 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：
更新日期：1992-01-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-018-0900-5
更新日期：2018-06-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：1989-05-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章,评审
doi：
更新日期：1989-03-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：10.1007/s13760-019-01137-z
更新日期：2019-04-13 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2003-03-01 00:00:00
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journal_title：Acta neurologica Belgica
pub_type： 杂志文章
doi：
更新日期：2002-06-01 00:00:00
