Abstract:
:Serum and cerebrospinal fluid (CSF) of 13 patients have been examined to confirm and precise the diagnosis of herpes simplex virus encephalitis (HSVE). By amplifying the DNA with a nested polymerase chain reaction (PCR), we could demonstrate the herpetic origin of these cases of encephalitis. DNA of HSV type 1 or type 2 was directly identified and differentiated, by the use of both type-specific primes in the same reaction. The primer sequences were chosen in the glycoprotein D region for HSV type 1, and in the glycoprotein G region for HSV type 2. Only one case was due to the latter. In all but one cases, an immunoaffinity-mediated capillary blotting study was also performed. This technique showed the occurrence of oligoclonal CSF-specific IgG bands, while the antigen-driven immunoblotting demonstrated intrathecal production of oligoclonal anti HSV antibodies. In most of the cases, repeated CSF analysis allowed us to study the sequential detection of viral DNA and of intrathecal synthesis of virus-specific IgG in relation to the clinical course. All the patients were treated with acyclovir. In one case, a relapse was clinically suspected, but the PCR remained negative.
journal_name
Acta Neurol Belgjournal_title
Acta neurologica Belgicaauthors
Monteyne P,Laterre EC,Sindic CJsubject
Has Abstractpub_date
1997-12-01 00:00:00pages
233-9issue
4eissn
0300-9009issn
2240-2993journal_volume
97pub_type
杂志文章abstract::Migraine headaches are common in children. Early diagnosis and appropriate interventions are mandatory to prevent decades of suffering and diminished quality of life. There is need for data regarding the efficacy and safety of prophylactic agents in children with migraine; therefore, we designed a randomized clinical ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,随机对照试验
doi:10.1007/s13760-012-0011-7
更新日期:2012-03-01 00:00:00
abstract::Inflammatory demyelinating polyradiculoneuropathy causes a spectrum of conditions ranging from acute (Guillain-Barré syndrome), through subacute to chronic forms. The pathogenesis of acute forms is related to antibody responses against glycolipid epitopes which mimic bacterial, especially Campylobacter jejuni, structu...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:2000-09-01 00:00:00
abstract::Osmotic demyelination syndrome (ODS) is the damage over the central nervous system caused by several electrolytes, metabolic and toxic disorders. We aimed to describe cases of unusual forms of ODS. In a 9-year period, 25 consecutive patients with ODS (15 men; mean age 42 years) were registered in our referral institut...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-012-0110-5
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:total removal of spinal hemangioblastomas with satisfactory clinical outcomes remains a challenge. We aimed to evaluate the surgical outcomes of our spinal hemangioblastomas patients, summarize our experiences with this condition and review-related literature. METHODS:records of 18 spinal hemangioblastoma pati...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01420-4
更新日期:2020-07-07 00:00:00
abstract::There is a need for new methods to study CSF proteins. Kerenyi et al., 1973 and Verheecke, 1975 have already used this method and discussed its advantages. The electrophoresis is carried out according to the method of Wieme with as supporting medium agar. The volume applied varies between 5 to 15 microliters according...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1979-07-01 00:00:00
abstract:UNLABELLED:Although there only have been a limited number of double-blind, placebo controlled trials, antipsychotics are considered to be effective drugs for the treatment of tics in Gilles de la Tourette syndrome (GTS). Evidence concerning the efficacy of olanzapine and other atypical antipsychotics in the treatment o...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2005-12-01 00:00:00
abstract::The case of a 57-year-old woman is described with a two months history of proximal muscle weakness and pain, marked hypotrophy and brisk reflexes. Clinical investigation demonstrated normal serum CK, myopathic EMG and osteomalacia. Muscle biopsy showed type II fibre atrophy and mitochondrial alterations without inclus...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1982-03-01 00:00:00
abstract::Diffuse multicentric sarcomas of the brain, also called cerebral malignant lymphomas, sometimes present symmetrical topography. This is well demonstrated by a CAT mirror image obtained by the authors in the reported case. The diagnostic value of the image is underlined in view of the possible forms of therapy, in part...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1980-03-01 00:00:00
abstract::The authors distinguish between two evolutive forms of dementia, one being chracterized by prpgressive deterioration (for instance in the course of arteriopathic, degenerative or infections processes) and the other in which dementia sets in after the clinical picture has improved (for instance after meningeal haemorrh...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1976-07-01 00:00:00
abstract::This retrospective study was performed to reevaluate the effect of polytherapy on mood and cognitive function. 139 patients with refractory epilepsy were screened with a neuropsychological test battery and a depression score. Our regression model with age at admission, duration of the disorder and number of antiepilep...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2011-03-01 00:00:00
abstract::Cervical artery dissection is a frequent cause of stroke, more so in young patients. Innominate artery (IA) dissection is uncommon, and most often associated with dissection of other major arteries like the aorta. The leading cause of IA injury is high-energy thoracic trauma, as in motor vehicle crash. IA dissection a...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-018-0945-5
更新日期:2018-12-01 00:00:00
abstract::Multiple sclerosis is considered to be an immune mediated inflammatory disorder of the central nervous system. It mainly affects young, socioeconomic active patients. Although our armamentarium for this disease has significantly evolved in recent years some patients remain refractory to conventional therapies. In thes...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-018-0905-0
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Increased intima-media thickness (IMT) of the common carotid arteries (CCA) and elevated levels of highly sensitive C-reactive protein (hsCRP) are both shown to be associated with the occurrence of stroke. We investigated whether elevated hsCRP level is a risk factor for the increased IMT of the CCA independ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2005-06-01 00:00:00
abstract::It has been shown that low-frequency stimulation (LFS) can induce anticonvulsant effects. In this study, the effect of different LFS frequencies on kindling induced behavioral and ultrastructural changes was investigated. For induction of kindled seizures in rats, stimulating and recording electrodes were implanted in...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-013-0243-1
更新日期:2014-03-01 00:00:00
abstract::As dystonia may represent a severe disease with possible fatal outcome or physical or social incapacity, and considering the limited efficacy of drug treatments (excepted doparesponsive dystonia), efforts have been made since the 1950s to propose alternative treatment. In this paper, an overview of the works done by n...
journal_title:Acta neurologica Belgica
pub_type: 传,历史文章,杂志文章
doi:
更新日期:2003-09-01 00:00:00
abstract::Nine cases (seven men and two women, mean age 64.5 years) of classical lacunar syndromes due to intracerebral hemorrhage are reported. Three patients presented with pure motor hemiparesis (two putaminal hematomas with proportional weakness and one cortical hemorrhage with brachio-crural hemiparesis). Four patients pre...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::We report an unusual case of probable progressive multifocal leukoencephalopathy (PML), who initially presented with a right-sided movement disorder, including upper limb dystonia, tremor, and dyspraxia, reminiscent of corticobasal degeneration. In the further course, the patient developed disorientation, confusion, a...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
abstract::Thromboelastography (TEG) is commonly used to predict coagulation state in patients with active bleeding. However, the correlation between TEG parameters and conventional tests in patients with cerebrovascular disease (CVD) remains unexplored. Here, we assessed the TEG values and their correlation with conventional te...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01456-6
更新日期:2020-08-05 00:00:00
abstract::To analyze the clinical characteristics and PRRT2 gene mutation of self-limited familial infantile epilepsy and evaluate the treatment responses of different antiepileptic drugs in self-limited familial infantile epilepsy. We reviewed the clinical feature and genetic mutation results and treatment responses of two sib...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01348-9
更新日期:2020-08-01 00:00:00
abstract::Oculomotor functions are analysed by clinical examination and oculography in 21 cases of deep cerebral hematoma. Significant paralysis of verticality and of movements contralateral to the lesions was observed in all cases where the hemorrhage affected the paramedian thalamo-subthalamic region. A slight deficit of elev...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1983-11-01 00:00:00
abstract::We investigated the ophthalmologic manifestations and factors that influence outcomes in patients with myasthenia gravis (MG). We retrospectively analyzed the prevalence of neuro-ophthalmologic findings and clinical and outcome measures of 100 consecutive patients (53 males, 47 females), aged 55.7 ± 17.5 (range 15-85)...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01556-3
更新日期:2021-01-04 00:00:00
abstract:: ...
journal_title:Acta neurologica Belgica
pub_type: 信件
doi:10.1007/s13760-018-0951-7
更新日期:2018-12-01 00:00:00
abstract::Needle insertion during electromyography (EMG) may cause varying levels of pain that could lead to inaccurate assessment and premature termination of the procedure. The aim of this study is to compare paracetamol 325 mg/tramadol 37.5 mg with placebo in relieving pain before EMG. This is a randomized, crossover, placeb...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,随机对照试验
doi:10.1007/s13760-016-0621-6
更新日期:2016-12-01 00:00:00
abstract::Eight cases of acute or subacute hypercalcemic encephalopathy are described. The symptoms comprise digestive disorders, signs of dehydration and neuropsychological anomalies. Among the latter, it is stressed that impairments of upright stance and locomotion are present in all cases. The clinical picture is not charact...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1977-05-01 00:00:00
abstract::The authors present the clinico-pathological correlation in a women who developed at the age of 43 years progressive pain in the left hemiface with motor and sensitive disorders of the left trigeminal nerve. Progressive involvement of the left IIIrd, IVth and Vth cranial nerves appeared with persistence of intractable...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::A case of isolated cerebral vasculitis showing benign outcome is presented. Review of pertinent literature suggests that isolated benign arteritis of the CNS should be considered as a distinct entity, in a heterogeneous group of vasculitides. The common features of the syndrome are as follows: 1(0) benign evolution; 2...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1984-08-01 00:00:00
abstract::The authors present and illustrate most of the ultrastructural abnormalities encountered in skeletal muscle in cases of neuromuscular disease. The diagnostic significance of the changes are discussed but emphasis is laid on the nonspecific character of most of them. For diagnostic purposes, examination by light micros...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1981-03-01 00:00:00
abstract::Diets that have effects on health problems can vary in their composition. Whilst following a regular diet (RD) a person typically consumes about 30% of calories from fat. Ketogenic diet (KD) is a form of diet whereby a person consumes as much as 90% of calories from fat. KD has been trialed as a treatment for neurolog...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01486-0
更新日期:2020-09-06 00:00:00
abstract::Central hypoventilation in adult patients is a rare life-threatening condition characterised by the loss of automatic breathing, more pronounced during sleep. In most cases, it is secondary to a brainstem lesion or to a primary pulmonary, cardiac or neuromuscular disease. More rarely, it can be a manifestation of cong...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:10.1007/s13760-020-01363-w
更新日期:2020-04-25 00:00:00
abstract:BACKGROUND:Meningiomas are common tumors of the central nervous system. Although most are benign tumors, approximately 10% show a histologic progression to a higher malignancy grade similar to atypical (GII) and anaplastic (GIII) meningiomas. Monosomy 22q12 is the most frequent genetic alteration detected in these tumo...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2002-06-01 00:00:00