Prolactin levels and autoantibodies in female patients with systemic lupus erythematosus.

Abstract:

:We investigated the relationships between prolactin (PRL) levels and antibody occurrence in systemic lupus erythematosus (SLE). No significant association between PRL levels and the majority of the autoantibodies studied (anti-U1 RNP, anti-rRNP, anti-Sm, anti-dsDNA, anti-DNP, auto-LCA, anti-EACA) could be confirmed (P > 0.05), anti-Ro/SSA antibodies being an exception. Our results showed significantly increased frequencies of these antibodies in the group of female SLE patients with normal PRL levels (< 20 micrograms/L): anti Ro/SSA in 53% (P < 0.025, chi 2 = 5.80, RR = 4.0) and anti-Ro/SSA + anti-Ro/La in 60% (P < 0.05, chi 2 = 4.05) compared with female SLE patients with hyperprolactinemia.

journal_name

Z Rheumatol

authors

Kozáková D,Rovenský J,Cebecauer L,Bosák V,Jahnová E,Vigas M

doi

10.1007/s003930070024

keywords:

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

II/80-4

eissn

0340-1855

issn

1435-1250

journal_volume

59 Suppl 2

pub_type

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