Current status of D-penicillamine therapy in Japan.

abstract：:In rheumatologic diseases magnet resonance imaging (MRI) is capable of depicting early inflammatory changes which are frequently missed by other imaging modalities. New MRI protocols and hardware, primarily whole-body MRI and low-field extremity MRI facilitate the use of MRI in rheumatology patients. The increasing nu...

journal_title：Zeitschrift fur Rheumatologie

authors： Buchbender C,Schneider M,Ostendorf B

更新日期：2013-03-01 00:00:00

abstract：:The neonatal lupus erythematosus syndrome, first described by McCuistion and Schoch in 1954, is associated with characteristic skin lesions and congenital heart block in the new-born, and the presence of Ro-(SSA), La-(SSB), or RNP antibodies in mothers and infants. A transplacental transference of maternal autoantibod...

journal_title：Zeitschrift fur Rheumatologie

authors： Mayet WJ,Hermann E,Bachmann M,Poralla T,Meyer zum Büschenfelde KH

更新日期：1989-03-01 00:00:00

abstract：:The treatment of rheumatic diseases with bioloics has significantly improved the prognosis of patients. Currently, there are 13 preparations available in Germany for the treatment of patients with inflammatory rheumatic diseases. These original preparations generally have-depending on the individual country-15 years o...

journal_title：Zeitschrift fur Rheumatologie

authors： Braun J,Lorenz HM,Müller-Ladner U,Schneider M,Schulze-Koops H,Specker C,Strangfeld A,Wagner U,Dörner T

更新日期：2018-02-01 00:00:00

abstract：:Involvement of the musculoskeletal system in 50 Lyme borreliosis patients seen in Czechoslovakia is described. Thirty-three patients reported tick bites or that they had removed a tick, four patients had been bitten by some other insect. Skin reaction following tick bite were found in 29 patients. Neurologic involveme...

journal_title：Zeitschrift fur Rheumatologie

authors： Valesová M,Trnavský K

更新日期：1990-07-01 00:00:00

abstract：:The painter Max Slevogt (1868-1932), together with Lovis Corinth and Max Liebermann, was one of the most important representatives of German impressionism. Slevogt, a gourmet who appreciated fine food and good wines, suffered from acute recurrent gouty arthritis starting at the age of 27 years. His medical history is ...

journal_title：Zeitschrift fur Rheumatologie

authors： Zeidler H

更新日期：2020-06-01 00:00:00

abstract：:The diagnosis of pyoderma gangraenosum was previously made as a diagnosis of exclusion. For this reason repeated attempts have been made in recent years to develop new diagnostic scores, whereby the typical clinical and anamnestic aspects were usually taken into account and the relevant differential diagnoses were exc...

journal_title：Zeitschrift fur Rheumatologie

authors： Dissemond J

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Since the introduction of biologic treatment in rheumatoid arthritis (RA), disease activity and treatment modalities have changed substantially. The current provision and developments in recent years are analyzed with annual data from the National Database of the Collaborative Arthritis Centers in Germany. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Albrecht K,Huscher D,Eidner T,Kleinert S,Späthling-Mestekemper S,Bischoff S,Zink A

更新日期：2017-02-01 00:00:00

abstract：:The assessment of off-label medications is one of the most common reasons for assessment of drugs for individual patients in the German medical services. Tension is not uncommon because of great expectations of patients and doctors on the one hand and the requirements of the law on the other. They often do not match. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Grell L,Rieger M

更新日期：2012-02-01 00:00:00

abstract：:In the thesis of the Irish physician Bernard Connor (1666-1698) from 1693 in Rheims he describes the torso of a man whose bones were joined together due to ankylosing spondylitis which is considered to be the first example of such skeletal findings. This communication must however be seen in connection with earlier an...

journal_title：Zeitschrift fur Rheumatologie

authors： Keitel W

更新日期：2012-06-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) is a mainstay in musculoskeletal imaging. The term"bone marrow edema" is frequently used for describing the radiological findings, especially with respect to rheumatic diseases. The referring physician should be aware that this term has a purely descriptive character and the pathophysi...

journal_title：Zeitschrift fur Rheumatologie

authors： Hamer OW,Kriegsmann J

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Reliable data on the course and treatment of pediatric COVID-19 ("corona virus disease 2019") in immunosuppressed patients with rheumatic diseases are missing. AIM:Delineation of individual strategies of the members of the Society for Pediatric Rheumatology (GKJR) in cases of COVID-19. METHODS:In May 2020 ...

journal_title：Zeitschrift fur Rheumatologie

authors： Janda A,Schuetz C,Heeg M,Minden K,Hedrich CM,Kallinich T,Hinze C,Schulz A,Speth F

更新日期：2020-09-01 00:00:00

abstract：:A dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis was found in animal models of chronic inflammatory diseases, and the defect was located in more central portions of the HPA axis. This defect of neuroendocrine regulatory mechanisms contributes to the onset of the model disease. Since these first observati...

journal_title：Zeitschrift fur Rheumatologie

authors： Straub RH,Schölmerich J,Zietz B

更新日期：2000-01-01 00:00:00

abstract：:Still's disease covers a range of disorders from systemic juvenile idiopathic arthritis (SJIA) up to adult onset Still's disease (AOSD). The overlapping clinical features suggest that SJIA and AOSD are different manifestations of a phenotypic continuum in different age stages. Still's disease is clinically characteriz...

journal_title：Zeitschrift fur Rheumatologie

authors： Föll D,Wittkowski H,Hinze C

更新日期：2020-09-01 00:00:00

abstract：:An attempt is made to compile the pharmacological data on the leading non-steroidal anti-inflammatory drugs. They concern the pharmacodynamics, the pharmacokinetics and the unwanted effects of these compounds. From these data a few suggestions for rational use are made: Ibuprofen and diclofenac present as drugs with s...

journal_title：Zeitschrift fur Rheumatologie

authors： Brune K

更新日期：1987-01-01 00:00:00

abstract：:By means of the 99m-Tc-pertechnitate joint scintigraphy the authors try to document the effect of antirheumatic drugs in 62 patients with rheumatoid arthritis. By measuring the changes of the synovial blood circulation, conclusions are drawn as to the degree of inflammation. When trying to make a quantitative assessme...

journal_title：Zeitschrift fur Rheumatologie

authors： Kafarnik D,Semmler U,Pfannenstiel P,Miehlke K

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:Scleromyxedema is a rare connective tissue disease that may affect numerous internal organs in addition to the skin. The disease is almost exclusively associated with monoclonal gammopathy. MATERIAL AND METHODS:This retrospective study summarizes the clinical characteristics of four patients with scleromyxe...

journal_title：Zeitschrift fur Rheumatologie

authors： Kreuter A,Stücker M,Kolios AG,Altmeyer P,Möllenhoff K

更新日期：2012-08-01 00:00:00

abstract：:Biochemical studies of rats with mycoplasma arthritis revealed new findings in pathogenesis and pathophysiology. Preliminary examinations showed that mycoplasmas release specific endonucleases and exonucleases. In evaluating the isoenzymes of the lactate dehydrogenases, malate dehydrogenases as well as of the esterase...

journal_title：Zeitschrift fur Rheumatologie

authors： Klein G

更新日期：1975-05-01 00:00:00

abstract：:Methotrexate (MTX) is a safe and well-tolerated drug for the treatment of rheumatic diseases, even if the strictest safety standards are considered. Initial apprehension as to severe pulmonary or hepatic side-effects has not been confirmed. The risk of infection is not elevated compared with other disease-modifying an...

journal_title：Zeitschrift fur Rheumatologie

authors： Keysser G

更新日期：2011-02-01 00:00:00

abstract：:Childhood onset rheumatic and musculoskeletal diseases often continue into adulthood. These diseases are associated with a high risk of permanent disability and impairment in the quality of life of people affected. Adolescence and young adulthood represent a particular risk phase for an unfavorable long-term outcome. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Minden K,Schalm S

更新日期：2016-08-01 00:00:00

abstract：:Conventional radiography, ultrasonography (US), magnetic resonance imaging (MRI), computed tomography, and scintigraphy are imaging techniques in use for rheumatoid arthritis (RA). Conventional radiography of the hands and the forefeet should be performed every 6 to 12 months in the first two years, and every 12 to 24...

journal_title：Zeitschrift fur Rheumatologie

authors： Kellner H,Schmidt W,Rau R

更新日期：2005-11-01 00:00:00

abstract：:A case is reported in which a patient with a rheumatoid factor-negative rheumatoid arthritis developed rheumatoid nodules in the penis during treatment with methotrexate. The development of rheumatoid nodules in seronegative rheumatoid arthritis patients is extremely rare. An acceleration of rheumatoid nodules in meth...

journal_title：Zeitschrift fur Rheumatologie

authors： Essig KM,Mayet WJ,Mottrie AM,Helmreich-Becker I,Meyer zum Büschenfelde KH

更新日期：1994-09-01 00:00:00

abstract：:The sulfhydryl groups are chemically active parts of the protein molecule and participate in many important biochemical and metabolic processes. The present material comprised 132 patients with rheumatoid arthritis, 104 patients with other diseases and 44 controls. The patients with rheumatoid arthritis had decreased ...

journal_title：Zeitschrift fur Rheumatologie

authors： Haataja M,Kalliomäki JL

更新日期：1977-03-01 00:00:00

abstract：:Alopecia universalis is an advanced form of alopecia areata, characterized by complete loss of hair on all hair-bearing areas. It is currently believed to be an autoimmune disorder. The development of alopecia during treatment with tumor necrosis factor alpha (TNF-α) inhibitors is a rarely observed adverse event. This...

journal_title：Zeitschrift fur Rheumatologie

authors： Ostojic P,Pavlov-Dolijanovic S

更新日期：2018-06-01 00:00:00

abstract：AIM:Our aim was to adapt and implement the evidence based recommendations for the management of ankylosing spodylitis (AS) of the "Assessments in AS" (ASAS) International Working Group together with the European League Against Rheumatism (EULAR) within the framework of a competence network (CN) in rheumatology in the G...

journal_title：Zeitschrift fur Rheumatologie

authors： Braun J,Zochling J,Märker-Hermann E,Stucki G,Böhm H,Rudwaleit M,Zeidler H,Sieper J

更新日期：2006-12-01 00:00:00

abstract：:MicroRNAs are small non-coding RNAs which are crucial for the fine regulation of gene expression. Recent results suggest that these molecules display multifaceted functions in B-cells and T-cells in rheumatic inflammatory diseases. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Wittmann J,Jäck HM,Mashreghi MF

更新日期：2011-08-01 00:00:00

abstract：:Biomarkers form the basis for patient stratification and the development of individualized treatment strategies. As the understanding of the pathophysiological processes underlying rheumatic diseases increases, novel biomarkers will become available and established markers can be used more efficiently. Autoantibodies ...

journal_title：Zeitschrift fur Rheumatologie

authors： Scherer HU,Burmester GR,Häupl T

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis is found in approximately 2 % of the total population in Europe and the peak incidence of the disease is during the fourth and fifth decades of life. In approximately 15 % the first symptoms of the disease occur at the level of the foot and ankle. If the early stage-dependent therapy wit...

journal_title：Zeitschrift fur Rheumatologie

authors： Thomas M,Jordan M

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Familial Mediterranean fever (FMF) in Germany is a rare, genetically linked disease of childhood and adolescence, which is characterized by recurrent febrile episodes and clinical signs of peritonitis, pleuritis and arthritis. Treatment with colchicine is effective and well-tolerated in the majority of patie...

journal_title：Zeitschrift fur Rheumatologie

authors： Kallinich T,Blank N,Braun T,Feist E,Kiltz U,Neudorf U,Oommen PT,Weseloh C,Wittkowski H,Braun J

更新日期：2019-02-01 00:00:00

abstract：:In the last years some important therapies were introduced in the treatment of rheumatoid arthritis (RA), which represent a significant clinical advance. This concerns the introduction of TNF blockade with etanercept and inflixmab, the combination of DMARDs, leflunomide and the COX-2-specific inhibitors. In the year 2...

journal_title：Zeitschrift fur Rheumatologie

authors： Edelmann E

更新日期：2001-12-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a classic systemic autoimmune disease. Standard treatment consists of chronic therapy with antimalarials, glucocorticoids and immunosuppressive/cytotoxic drugs, which is associated with considerable side effects. In contrast, immunoablation of autoreactive immunologic memory follo...

journal_title：Zeitschrift fur Rheumatologie

authors： Alexander T,Arnold R,Hiepe F

更新日期：2009-05-01 00:00:00