[Prospective study of JCR-Oligo I of the Child and Adolescence Rheumatology Working Group].

abstract：:In the last years some important therapies were introduced in the treatment of rheumatoid arthritis (RA), which represent a significant clinical advance. This concerns the introduction of TNF blockade with etanercept and inflixmab, the combination of DMARDs, leflunomide and the COX-2-specific inhibitors. In the year 2...

journal_title：Zeitschrift fur Rheumatologie

authors： Edelmann E

更新日期：2001-12-01 00:00:00

abstract：:Because it is a systemic disorder, rheumatoid arthritis (RA) is known to predispose affected individuals to other organ manifestations as well as arthritic problems. The serious complications include pericarditis, pulmonary and cutaneous nodules, episcleritis, and rheumatoid vasculitis. Of late, a significantly increa...

journal_title：Zeitschrift fur Rheumatologie

authors： Whelan P

更新日期：2006-10-01 00:00:00

abstract：AIM:To explore the circadian rhythm of serum interleukin (IL)-6 in collagen-induced arthritis (CIA) rats and compare the safety and effectiveness of methotrexate (MTX) administered traditionally and via chronotherapy. METHODS:CIA rat models were immunized with bovine type II collagen. Serum IL-6 levels in normal and C...

journal_title：Zeitschrift fur Rheumatologie

authors： Wang X,Yan X,Wang F,Ge F,Li Z

更新日期：2018-04-01 00:00:00

abstract：:Facing increasing health-related costs and limited health care resources, the assessment of cost effectiveness (CE) of medical procedures is also gaining considerable importance in the field of rheumatology. Since high annual therapy costs of 17,000-21,000 Euro are related to the employment of TNF-alpha blocking agent...

journal_title：Zeitschrift fur Rheumatologie

authors： Merkesdal S,Ruof J

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Clinical observation suggests a frequent coincidence of back pain (BP) and fibromyalgia (FMA). Based on data from a population survey on back pain we studied the hypothesis of FMA being a frequent underlying condition of BP. We additionally studied the association of the severity of back pain and both chroni...

journal_title：Zeitschrift fur Rheumatologie

authors： Hüppe A,Brockow T,Raspe H

更新日期：2004-02-01 00:00:00

abstract：:The commission "Rehabilitation" of the German Society of Rheumatology compiled a data set for a routine report of the rehabilitation system for muskuloskeletal diseases. More than 250 rehabilitation hospitals offer inpatient rehabilitation for patients with musculoskeletal diseases. The prevalence of inpatient rehabil...

journal_title：Zeitschrift fur Rheumatologie

authors： Jäckel WH,Mau W,Zink A,Beyer W,Droste U,Engel M,Genth E

更新日期：2005-06-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) results from loss of immunological tolerance. Regulatory T‑cells (Treg) are major gatekeepers of peripheral tolerance by suppression of autoreactive lymphocytes. Defects in Treg function are therefore possible pathogenetic mechanisms of SLE. Despite this fact published work about num...

journal_title：Zeitschrift fur Rheumatologie

authors： Ohl K,Tenbrock K

更新日期：2016-04-01 00:00:00

abstract：:Systemic disease demands systemic thinkers. In this mission statement we define rheumatology, describe the role of the German Society of Rheumatology and the rheumatologist's spirit to their discipline. Rheumatologists are dedicated to improving the quality of life of their acute, chronic, and rehabilitative patients ...

journal_title：Zeitschrift fur Rheumatologie

authors： Lorenz HM,Aringer M,Braun J,Hoyer BF,Krause A,Meyer-Olson D,Mucke J,Rudwaleit M,Schneider M,Sewerin P,Späthling-Mestekemper S,Specker C,Voormann A,Wagner U,Wendler J,Schulze-Koops H

更新日期：2020-12-01 00:00:00

abstract：:The "German Society of Rheumatology" was founded in Bad Neuenahr in the Federal Republic of Germany In 1947. The society perceived itself as the successor to the "German Society for the Abatement of Rheumatism". The primary aim of the society was close cooperation with other German-speaking rheumatological societies i...

journal_title：Zeitschrift fur Rheumatologie

authors： Hewelt T

更新日期：2011-01-01 00:00:00

abstract：:Diagnosis and management of the rare disease systemic sclerosis (scleroderma) is a challenge for the physician, not least due to the possible multitude of organ systems involved. The medico-legal assessment is important for the patient claiming insurance benefits or applying for early retirement due to scleroderma. Bo...

journal_title：Zeitschrift fur Rheumatologie

authors： Graninger M

更新日期：2007-10-01 00:00:00

abstract：:Sjögren's syndrome is a systemic inflammatory rheumatic disorder of unknown origin with so far inadequate therapy options. Management of Sjögren's syndrome is still primarily palliative using local symptomatic measures, and if appropriate glucocorticoids, NSAIDs and immunosuppressive drugs. New clues to the pathogenes...

journal_title：Zeitschrift fur Rheumatologie

authors： Feist E,Dörner T,Hansen A

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:The choice between outpatient and inpatient care is currently undergoing major changes within the German health care system with the amendment of § 116b SGB V. This study investigates what proportion of hitherto inpatient rheumatologic care could potentially be given on an outpatient basis. METHODS:The anal...

journal_title：Zeitschrift fur Rheumatologie

authors： Rath T,Bokern E,Sefo-Bukow E,Büscher G,Lüngen M,Rubbert-Roth A

更新日期：2011-01-01 00:00:00

abstract：:Cytokine driven inflammation is a common feature in autoimmune diseases. Cytokines are needed under physiological conditions within the innate and adaptive immune systems to control infectious diseases and neoplastic disorders by regulation of the cell cycle and apoptosis. Cytokines can also be found in persistently i...

journal_title：Zeitschrift fur Rheumatologie

authors： Feuchtenberger M,Kneitz C,Tony HP

更新日期：2007-07-01 00:00:00

abstract：:An attempt is made to compile the pharmacological data on the leading non-steroidal anti-inflammatory drugs. They concern the pharmacodynamics, the pharmacokinetics and the unwanted effects of these compounds. From these data a few suggestions for rational use are made: Ibuprofen and diclofenac present as drugs with s...

journal_title：Zeitschrift fur Rheumatologie

authors： Brune K

更新日期：1987-01-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) is a mainstay in musculoskeletal imaging. The term"bone marrow edema" is frequently used for describing the radiological findings, especially with respect to rheumatic diseases. The referring physician should be aware that this term has a purely descriptive character and the pathophysi...

journal_title：Zeitschrift fur Rheumatologie

authors： Hamer OW,Kriegsmann J

更新日期：2012-01-01 00:00:00

abstract：:The effect of meloxicam, a new non-steroidal anti-inflammatory drug, on spontaneous osteoarthrosis of the ankle joint in Crl: CDBR rats was investigated. The drug was administered in the feed at doses of 0.4, 0.6 and 0.8 mg/kg/day over a period of 2 years to 50 males and 50 females per dose. 100 male rats and 100 fema...

journal_title：Zeitschrift fur Rheumatologie

authors： Mohr W,Lehmann H,Engelhardt G

更新日期：1997-01-01 00:00:00

abstract：:Rehabilitation activities belong to tertiary prevention. The latter includes all measures that aim at avoiding the progression of a physical disability to a handicap, or those that diminish the extent of the handicap. Complex rehabilitation programs represent a cooperation of medical, occupational, and social reintegr...

journal_title：Zeitschrift fur Rheumatologie

authors： Wessel G,Leistner K

更新日期：1990-09-01 00:00:00

abstract：:From the about 400 virus species known to cause illness in man, only a small but growing list of representatives are able to induce arthritis. Although virus-associated arthritides are mostly of acute and short-living type, some patients develop long-lasting or even chronic joint inflammation. The viral or host factor...

journal_title：Zeitschrift fur Rheumatologie

authors： Saal JG

更新日期：1995-11-01 00:00:00

abstract：:Rheumatoid arthritis (RA) represents an autoimmune disease affecting mostly joints, in particular small finger and toe joints. In addition RA can show extra-articular manifestations in many organs. Information on the frequency of extra-articular manifestations (EAMs) in RA varies greatly in different publications from...

journal_title：Zeitschrift fur Rheumatologie

authors： Baerwald C,Kneitz C,Bach M,Licht M

更新日期：2012-12-01 00:00:00

abstract：:The antidesoxyribonuclease B reaction shows in persons of all classes of age examined a similar distribution of titres as the antistreptolysin reaction. The anti DNase B titres however are mostly lower than the titres of the antistreptolysin reaction, except in the group of children, 6 to 17 years of age, suffering fr...

journal_title：Zeitschrift fur Rheumatologie

authors： Otto R,Richter M,Scholz E,Neumann G

更新日期：1981-01-01 00:00:00

abstract：:Progressive multifocal leukoencephalopathy (PML) is a rare but often fatal demyelinating disease of the central nervous system induced by the JC virus. It mainly occurs in immunocompromised patients. Growing interest in rheumatology has arisen from reports of patients with rheumatic diseases suffering from PML. A dire...

journal_title：Zeitschrift fur Rheumatologie

authors： Kneitz C,Wiendl H

更新日期：2008-07-01 00:00:00

abstract：:Heavy physical work load is a known determinant of osteoarthritis of the hip, which may account for the high risk observed among farmers. On the other hand, the data on influence of heavy manual work in the pathogenesis of hand osteoarthritis are still controversial. We examined 25 retired farm laborers who strenuousl...

journal_title：Zeitschrift fur Rheumatologie

authors： Schmid L,Dreier D,Muff B,Allgayer B,Schlumpf U

更新日期：1999-12-01 00:00:00

abstract：:ECG from 200 patients with radiologically and clinically definite rheumatoid arthritis were compared with those from a healthy group with the same age and sex distribution. The frequency of pathological changes of the ECG was found to be the same in both groups. Therefore doubt remains whether the pathological changes...

journal_title：Zeitschrift fur Rheumatologie

authors： Droste U,Zimmermann H

更新日期：1979-07-01 00:00:00

abstract：:The duration and severity of rheumatic diseases of the shoulder correlate with symptom frequency, structural changes and associated functional limitations. The multifactorial character of the underlying rheumatic disease requires a multimodal therapeutic concept including interaction of surgical and non-surgical disci...

journal_title：Zeitschrift fur Rheumatologie

authors： Heers G,Grifka J,Springorum HR,Craiovan B,Anders S

更新日期：2015-11-01 00:00:00

abstract：:Rheumatoid vasculitis usually occurs on the background of seropositive rheumatoid arthritis, although in rare cases the patients can be seronegative. We report a woman with seronegative rheumatoid arthritis with rheumatoid vasculitis who developed toxic epidermal necrolysis involving most of her body surface area, whi...

journal_title：Zeitschrift fur Rheumatologie

authors： Chowdhury AC,Misra DP,Patro PS,Agarwal V

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To assess the relative efficacy and safety of apremilast, secukinumab, and ustekinumab at different doses in patients with active psoriatic arthritis (PsA). METHOD:A Bayesian network meta-analysis was conducted, which included randomized controlled trials (RCTs) that examined the efficacy and safety of aprem...

journal_title：Zeitschrift fur Rheumatologie

authors： Song GG,Lee YH

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Taking part in physical education is an important element of social participation for children with chronic diseases. Nevertheless, children suffering from rheumatism mostly receive recommendations to stop sport activities either completely or partially, without underlying scientific guidelines. OBJECTIVE:T...

journal_title：Zeitschrift fur Rheumatologie

authors： Hartmann M,Merker J,Schrödl S,König M,Georgi M,Hinze C,Schwirtz A,Haas JP

更新日期：2018-10-01 00:00:00

abstract：:Autoinflammatory syndromes are characterized by periodic febrile attacks in combination with increased inflammatory markers. The dysregulation of different cellular signaling pathways leads to an excessive immune response, which can in turn promote multisystemic inflammatory processes. Due to overlapping symptoms, var...

journal_title：Zeitschrift fur Rheumatologie

authors： Schnappauf O

更新日期：2020-09-01 00:00:00

abstract：:Behçet's disease (BD) is a recurrent, multisystemic, inflammatory blood vessel disorder that can result in mouth, genital, and skin ulcers; arthritis; and eye and intestinal inflammation. We describe a 21-year-old Korean female patient with intestinal BD refractory to conventional medical treatment and biologic drugs....

journal_title：Zeitschrift fur Rheumatologie

authors： Kim HJ,Kim KT,Lee SG,Kim Y

更新日期：2020-09-01 00:00:00

abstract：:Performing histo-morphologic studies of knee joints in several hundred mice of the strains C57 black, STR/1N and MAGf, showing a disposition for spontaneous osteo-arthrosis, we found tentative reparative processes in many cases. There was a proliferation of cartilage and of the synovial membrane, mostly in the periphe...

journal_title：Zeitschrift fur Rheumatologie

authors： Wilhelmi G,Schneider-Faust R

更新日期：1984-09-01 00:00:00