Fatigue in systemic lupus erythematosus : Association with disease activity, quality of life and psychosocial factors.

abstract：:Five to 9 months after a comparative study of 2 groups of patients with coxarthrosis and gonarthrosis, 69 individuals (group 1) receiving Arteparon forte injections and physical therapy and 46 persons (group 2) with physical therapy only, questioneer with specific questions was sent out. From 72 questioneers mailed 55...

journal_title：Zeitschrift fur Rheumatologie

authors： Rau E,Schmid C,Bach GL

更新日期：1977-07-01 00:00:00

abstract：:Serum protein binding of naproxen is considerably reduced in patients with renal insufficiency. The hypothetical plasma concentration at time zero and the half life are not significantly altered in uremic patients in comparison with healthy subjects when the drug is given orally. This suggests an increased pharmacodyn...

journal_title：Zeitschrift fur Rheumatologie

authors： Held H

更新日期：1979-03-01 00:00:00

abstract：:Antibodies to double-stranded DNA (anti-dsDNA, dsDNA-Ab) are frequently found in systemic lupus erythematosus (SLE), especially during active disease and differ with respect to immunoglobulin class and avidity. The detection of anti-dsDNA is one of the diagnostic criteria for SLE according to the American College of R...

journal_title：Zeitschrift fur Rheumatologie

authors： Wigand R,Gottschalk R,Falkenbach A,Matthias T,Kaltwasser JP,Hoelzer D

更新日期：1997-03-01 00:00:00

abstract：:D-penicillamine treatment of 50 patients with rheumatoid arthritis with negative ANF tests, was followed by means of protein disk electrophoresis of the urine. In the beginning the urine proteins were analysed every 4 weeks, later at intervals of 3 to 6 months. A glomerular proteinuria, caused by an immune-complex nep...

journal_title：Zeitschrift fur Rheumatologie

authors： Rautenstrauch H

更新日期：1977-11-01 00:00:00

abstract：:278 patients with ankylosing spondylitis have been studied in order to find a basis for prognosis by setting a mobility function index of the vertebral column. This index does not depend on manifestation age or on the blood sedimentation rate. It increases with progression of x-ray findings. A coincidence of impaired ...

journal_title：Zeitschrift fur Rheumatologie

authors： Schöffel J,Pohl W

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease affecting a broad range of different organ systems and, hence, presenting with multiple symptomatic domains, which considerably reduces the quality of life of patients. Within the last decade the prognosis of the disease has been...

journal_title：Zeitschrift fur Rheumatologie

authors： Schneider M,Haupt M

更新日期：2015-09-01 00:00:00

abstract：:OM 8930, a bacterial product with immunostimulatory capacities, was studied for its efficacy in the long-term treatment of rheumatoid arthritis (RA). Ten (10) patients with active seropositive rheumatoid arthritis were treated intermittently for six months with the agent and were evaluated according to clinical, labor...

journal_title：Zeitschrift fur Rheumatologie

authors： Rosenthal M,Plattner S

更新日期：1981-09-01 00:00:00

abstract：:Osteoarthritis is the most common joint disease. In addition to known risk factors e.g. genetics, age and hormonal status it has been suggested that chronic-repetitive micro- and substantial (macro-) injury may play an important pathogenetic role. In a longitudinal case-study we examined Judo-players for clinical and ...

journal_title：Zeitschrift fur Rheumatologie

authors： Strasser P,Hauser M,Häuselmann HJ,Michel BA,Frei A,Stucki G

更新日期：1997-12-01 00:00:00

abstract：:The development of synovitis was studied in 64 rabbits with experimentally produced allergic arthritis and in 30 rabbits with experimentally produced non-allergic arthritis. The results are compared with the morphological changes of the synovial membrane in rheumatoid arthritis, especially in early stages, known from ...

journal_title：Zeitschrift fur Rheumatologie

authors： Püschel W

更新日期：1982-01-01 00:00:00

abstract：:Systemic disease demands systemic thinkers. In this mission statement we define rheumatology, describe the role of the German Society of Rheumatology and the rheumatologist's spirit to their discipline. Rheumatologists are dedicated to improving the quality of life of their acute, chronic, and rehabilitative patients ...

journal_title：Zeitschrift fur Rheumatologie

authors： Lorenz HM,Aringer M,Braun J,Hoyer BF,Krause A,Meyer-Olson D,Mucke J,Rudwaleit M,Schneider M,Sewerin P,Späthling-Mestekemper S,Specker C,Voormann A,Wagner U,Wendler J,Schulze-Koops H

更新日期：2020-12-01 00:00:00

abstract：:Cartilage destruction in arthritis and osteoarthritis is linked to aberrant cytokine and growth factor expression in the affected tissues. It becomes clear that the balance of protective and destructive cytokines is more important for the net destruction than the absolute levels of destructive mediators. IL-1 is a key...

journal_title：Zeitschrift fur Rheumatologie

authors： van den Berg WB

更新日期：1999-06-01 00:00:00

abstract：:The assessment of off-label medications is one of the most common reasons for assessment of drugs for individual patients in the German medical services. Tension is not uncommon because of great expectations of patients and doctors on the one hand and the requirements of the law on the other. They often do not match. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Grell L,Rieger M

更新日期：2012-02-01 00:00:00

abstract：:The revised S2 guidelines for treatment of giant cell arteritis have recently been published. Glucocorticosteroids remain the standard first line treatment. For severe or relapsing courses of the disease, the IL‑6 antagonist tocilizumab, a potent antibody, is now available as a therapeutic option; however, how long th...

journal_title：Zeitschrift fur Rheumatologie

authors： Henes J

更新日期：2020-12-22 00:00:00

abstract：:Within the group of inflammatory rheumatic diseases, spondyloarthropathy is the most common diagnosis after rheumatoid arthritis. Its prevalence was long underestimated. Ankylosing spondylitis (AS) and undifferentiated spondyloathropathy (uSpA) are the most common subgroups in western countries. There are still diffic...

journal_title：Zeitschrift fur Rheumatologie

authors： Haibel H,Rudwaleit M,Braun J,Sieper J

更新日期：2002-02-01 00:00:00

abstract：:30 patients with hepatitis, 50 patients with gynecological diseases, and 100 with urological diseases were investigated with regards to lumbago to find out whether there is a correlation between the internal disease and the signs of low back pain. The patients were compared with a control group of 33 healthy people. T...

journal_title：Zeitschrift fur Rheumatologie

authors： Tilscher H,Bogner G,Landsiedl F

更新日期：1977-05-01 00:00:00

abstract：:Up to now stratified therapy concepts have not played an important role in the treatment of patients with rheumatoid arthritis; however, a high heterogeneity regarding the effectiveness of therapies and occurrence of side effects in patients with the same indications provokes research efforts aiming at identifying and...

journal_title：Zeitschrift fur Rheumatologie

authors： Frank M,Mittendorf T

更新日期：2013-02-01 00:00:00

abstract：:A dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis was found in animal models of chronic inflammatory diseases, and the defect was located in more central portions of the HPA axis. This defect of neuroendocrine regulatory mechanisms contributes to the onset of the model disease. Since these first observati...

journal_title：Zeitschrift fur Rheumatologie

authors： Straub RH,Schölmerich J,Zietz B

更新日期：2000-01-01 00:00:00

abstract：:Mainly due to the general demographic changes and decreasing mortality in rheumatic diseases based on therapeutic progress, the proportion of older patients treated by rheumatologists is growing. Drug treatment in the elderly, however, harbors certain risks including age-specific pharmacokinetic features and high rate...

journal_title：Zeitschrift fur Rheumatologie

authors： Krüger K,Strangfeld A,Kneitz C

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:The treatment strategies for osteoarthritis (OA) are well known from numerous studies. One of the challenges is long-term patient compliance to the recommended therapies without supervision. OBJECTIVE:To examine the ability of salutogenic concepts to improve rehabilitative management of OA. MATERIALS AND M...

journal_title：Zeitschrift fur Rheumatologie

authors： Benz T,Aeschlimann A,Angst F

更新日期：2015-09-01 00:00:00

abstract：INTRODUCTION:Only insufficient data are available regarding the question whether treatment with immunosuppressants or biologicals is feasible and safe in patients with a history of malignancy. METHOD:Literature search via PubMed, EULAR abstracts and ACR abstracts from 2013 to 2015. RESULTS:The Société Francaise de Rh...

journal_title：Zeitschrift fur Rheumatologie

authors： Schmalzing M,Strangfeld A,Tony HP

更新日期：2016-02-01 00:00:00

abstract：:Arthrosis deformans is a common disease worldwide with a high prevalence among all ethnic groups. All joints may be affected and genetic factors influence the onset of the disease. The main symptoms include pain and increasing immobility over the course of the illness. Treatment in early stages is conservative. In the...

journal_title：Zeitschrift fur Rheumatologie

authors： Rehart S,Lehnert H

更新日期：2008-07-01 00:00:00

abstract：:An appropriate treatment of elderly rheumatic patients implements comprehensive diagnostics and exclusion diagnostics of e.g. coronary heart disease, osteoporosis, renal failure, diabetes mellitus type 2 and thyroid gland dysfunction. Furthermore, the complex disease situation might require the integration of other fa...

journal_title：Zeitschrift fur Rheumatologie

authors： Lakomek HJ,Brabant T,Lakomek M,Lüttje D

更新日期：2013-08-01 00:00:00

abstract：:Heberden nodes affect mainly middle-aged women. Inheritance is autosomal dominant in female and autosomal recessive in male patients. We report the case of a young man who presented already with 12 years of age with pain in the distal finger joints. There were no other clinical or serological signs for other rheumatoi...

journal_title：Zeitschrift fur Rheumatologie

authors： Rascu A,Kraetsch HG,Grünke M,Kalden JR,Manger B

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Since the introduction of biologic treatment in rheumatoid arthritis (RA), disease activity and treatment modalities have changed substantially. The current provision and developments in recent years are analyzed with annual data from the National Database of the Collaborative Arthritis Centers in Germany. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Albrecht K,Huscher D,Eidner T,Kleinert S,Späthling-Mestekemper S,Bischoff S,Zink A

更新日期：2017-02-01 00:00:00

abstract：:Our aim is to present a new method to examine spinal mobility and spine shape excluding torsional scoliosis. In comparison to measuring devices of the spine used so far, this noninvasive and easy to use method documents altered patterns of intervertebral mobility of the lumbar and thoracic spine. This may lead to a br...

journal_title：Zeitschrift fur Rheumatologie

authors： Hauns B,Ovenhausen K,Hase P,Lorenzen W,Mennet P,Stratz T,Müller W

更新日期：1994-05-01 00:00:00

abstract：:Commonly-used serological methods for the determination of Yersinia antibodies are based on the presence of agglutinins, which are frequently absent or of low titer when arthritis begins. Stool cultures are usually negative at that time, so many Yersinia infections are underdiagnosed. On the other hand, significant ag...

journal_title：Zeitschrift fur Rheumatologie

authors： Grasedyck K,Heesemann J

更新日期：1987-07-01 00:00:00

abstract：:In a double-blind study, glycosaminoglycan polysulfate (GAGPS, Arteparon) was compared to saline solution: both preparations were applied intramuscularly in two groups of 70 patients, each over a period of 8 weeks. The patients were suffering from pain and impaired function of the knee and hip joints. To assess the th...

journal_title：Zeitschrift fur Rheumatologie

authors： Siegmeth W,Radi I

更新日期：1983-07-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) results from loss of immunological tolerance. Regulatory T‑cells (Treg) are major gatekeepers of peripheral tolerance by suppression of autoreactive lymphocytes. Defects in Treg function are therefore possible pathogenetic mechanisms of SLE. Despite this fact published work about num...

journal_title：Zeitschrift fur Rheumatologie

authors： Ohl K,Tenbrock K

更新日期：2016-04-01 00:00:00

abstract：:The modified significance of radiological criterion in the new ACR/EULAR classification criteria for rheumatoid arthritis is based on the fact that the bone erosion seen using conventional radiology is the result of an already longstanding inflammatory process.In contrast, new imaging modalities such as magnetic reson...

journal_title：Zeitschrift fur Rheumatologie

authors： Strunk J

更新日期：2011-04-01 00:00:00

abstract：:The histopathological synovitis score evaluates in a graded approach, as is largely usual for diagnostic histopathological scores, the immunological and inflammatory changes caused by synovitis. A synovitis score of between 1 and ≤ 4 is classified as low-grade (osteoarthritis-related synovitis, post-traumatic synoviti...

journal_title：Zeitschrift fur Rheumatologie

authors： Krenn V,Perino G,Rüther W,Krenn VT,Huber M,Hügle T,Najm A,Müller S,Boettner F,Pessler F,Waldstein W,Kriegsmann J,Häupl T,Wienert S,Krukemeyer MG,Sesselmann S,Tikhilov R,Morawietz L

更新日期：2017-08-01 00:00:00