The coexistence of mutilating rheumatoid arthritis, progressive systemic sclerosis and polycythemia vera--a case report.

abstract：:Rheumatoid arthritis (RA) is associated with a shortened life expectancy. Most premature deaths are caused by cardiovascular (CV) events; therefore it is of importance to consider the increased CV risk when treating RA patients. Traditional CV risk factors cannot fully explain the increased risk but the common underst...

journal_title：Zeitschrift fur Rheumatologie

authors： Pieringer H,Hoppe UC

更新日期：2013-05-01 00:00:00

abstract：:After clinical and radiological examination, the elbows of 74 patients with rheumatoid arthritis were examined by ultrasound. Clinical examination gives a good impression of the inflammatory changes of the elbow joint. Sonography was very useful in detecting synovitis and joint effusion and their distribution in the d...

journal_title：Zeitschrift fur Rheumatologie

authors： Sell S,König S,Zacher J

更新日期：1993-05-01 00:00:00

abstract：:The effect of recombinant interleukin-2 (IL-2) on proliferative and cytotoxic response of peripheral blood mononuclear cells (PBMC) was investigated in a group of 21 patients with systemic lupus erythematosus (SLE). There was a significant decrease in thymidine uptake of peripheral blood mononuclear cells when compare...

journal_title：Zeitschrift fur Rheumatologie

authors： Jira M,Strejcek J,Zavadil Z,Antosova E,Rejholec V

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Recent data provided evidence on the implication of the adipocytokines adiponectin, visfatin, and resistin in inflammation, immune response, and tissue destruction and revealed several links between them and arthritis. AIM OF THE STUDY:The purpose of this study was to assess the levels of adiponectin, visfa...

journal_title：Zeitschrift fur Rheumatologie

authors： Alkady EA,Ahmed HM,Tag L,Abdou MA

更新日期：2011-09-01 00:00:00

abstract：:The aim of this review is to critically analyze the evidence of therapeutic ultrasound between 0.8 and 3 MHz for treating musculoskeletal diseases. Relevant randomized, controlled, clinical trials and systematic reviews published on this topic have been taken into consideration.There was evidence of effectiveness for ...

journal_title：Zeitschrift fur Rheumatologie

authors： Ebenbichler G

更新日期：2009-09-01 00:00:00

abstract：UNLABELLED:The regulatory region of the corticotropin releasing hormone (CRH) is highly conserved and plays a crucial role in the response of the organism to stress. Release of CRH initiates a cascade of events leading to the release of cortisone and the regulation of inflammatory and immune events. OBJECTIVE:Since it...

journal_title：Zeitschrift fur Rheumatologie

authors： Baerwald CG,Mok CC,Tickly M,Lau CS,Wordsworth BP,Ollier B,Panayi GS,Lanchbury JS

更新日期：2000-02-01 00:00:00

abstract：:Serum protein binding of naproxen is considerably reduced in patients with renal insufficiency. The hypothetical plasma concentration at time zero and the half life are not significantly altered in uremic patients in comparison with healthy subjects when the drug is given orally. This suggests an increased pharmacodyn...

journal_title：Zeitschrift fur Rheumatologie

authors： Held H

更新日期：1979-03-01 00:00:00

abstract：:Self-administered patient-centered questionnaires have been shown to be practical, reliable and valid in terms of evaluating functional limitations in rheumatic diseases. In systemic sclerosis a modified version of the HAQ and condition-specific questionnaires have been used. The Health Assessment Questionnaire (HAQ) ...

journal_title：Zeitschrift fur Rheumatologie

authors： Sigl T,Ewert T,Stucki G

更新日期：2004-12-01 00:00:00

abstract：:The diagnosis of rheumatoid arthritis has been hampered by the lack of a truly disease-specific serologic marker. Thus, despite its moderate specificity rheumatoid factor (RF) is still the only established marker antibody for RA and among the diagnostic criteria of the American College of Rheumatology the only serolog...

journal_title：Zeitschrift fur Rheumatologie

authors： Steiner G,Smolen JS

更新日期：2002-12-01 00:00:00

abstract：:Polyarthralgias are widely common complaints. In earlier stages it might be difficult to state the right diagnosis. Differential diagnosis is absolutely necessary for starting in time with the right treatment. Out of a great clinical material the following diseases causing mono-, oligo- or polyarthralgia were discusse...

journal_title：Zeitschrift fur Rheumatologie

authors： Singer F

更新日期：1982-01-01 00:00:00

abstract：:Biomarkers form the basis for patient stratification and the development of individualized treatment strategies. As the understanding of the pathophysiological processes underlying rheumatic diseases increases, novel biomarkers will become available and established markers can be used more efficiently. Autoantibodies ...

journal_title：Zeitschrift fur Rheumatologie

authors： Scherer HU,Burmester GR,Häupl T

更新日期：2013-02-01 00:00:00

abstract：:The enzyme poly-(ADP-ribose) polymerase (PARP) is localized within the cell nucleus and catalyzes DNA-repair. During programmed cell death (apoptosis), PARP is enzymatically cleaved. Detection of the cleavage products is characteristic for apoptosis. In patients with systemic lupus erythematosus (SLE), the highly orde...

journal_title：Zeitschrift fur Rheumatologie

authors： Böhm I

更新日期：2006-10-01 00:00:00

abstract：:Fifty-seven patients with rheumatoid arthritis were examined clinically, radiologically, and by means of transcranial magnetic brain stimulation. With this method central motor conduction times of the corticospinal pathways can be measured. The aim of the study was to compare the different methods to detect a cervical...

journal_title：Zeitschrift fur Rheumatologie

authors： Theiler R,Dvorak J,Janssen B,Baumgartner H,Herdmann J

更新日期：1990-09-01 00:00:00

abstract：:Recent Deutsche Gesellschaft für Rheumatologie (DGRh, German Society of Rheumatology) guidelines emphasized the significance of coordinated multidisciplinary care and rehabilitation of patients with inflammatory rheumatic diseases. Nationwide data from the German pension insurance funds showed that inpatient rehabilit...

journal_title：Zeitschrift fur Rheumatologie

authors： Mau W,Beyer W,Ehlebracht-König I,Engel JM,Genth E,Jäckel WH,Lange U,Thiele K

更新日期：2014-03-01 00:00:00

abstract：:The effect of meloxicam, a new non-steroidal anti-inflammatory drug, on spontaneous osteoarthrosis of the ankle joint in Crl: CDBR rats was investigated. The drug was administered in the feed at doses of 0.4, 0.6 and 0.8 mg/kg/day over a period of 2 years to 50 males and 50 females per dose. 100 male rats and 100 fema...

journal_title：Zeitschrift fur Rheumatologie

authors： Mohr W,Lehmann H,Engelhardt G

更新日期：1997-01-01 00:00:00

abstract：:In recent years, new findings in immunology have been successfully converted to therapeutic principles, in particular for rheumatoid arthritis (RA) and spondylarthritides. The introduction of cytokine blockers in RA using tumor necrosis factor (TNF)-alpha and interleukin (IL)-1 inhibitors presented the first original ...

journal_title：Zeitschrift fur Rheumatologie

authors： Mei H,Dörner T

更新日期：2009-07-01 00:00:00

abstract：:Osteoid osteomas are painful bone tumors that usually occur in childhood or adolescence. Despite the small size of the bony lesions osteoid osteomas can cause persistent pain. Pathogenesis has not been completely understood. Remission usually occurs within several months to years. Therefore surgical therapy is not ind...

journal_title：Zeitschrift fur Rheumatologie

authors： Hedrich CM,Fiebig B,Sallmann S,Bruck N,Thielemann F,Hahn G,Heubner G,Gahr M

更新日期：2008-03-01 00:00:00

abstract：:Large data bases and the projects arising from them have led to a much improved understanding of systemic sclerosis over the last decade. Serology has developed further so that more autoantibodies are available for routine testing. Capillary microscopy has become standard and relevant progress has also been made in th...

journal_title：Zeitschrift fur Rheumatologie

authors： Aringer M,Müller-Ladner U,Burkhardt H,Distler JH,Distler O,Graninger WB,Günther C,Hunzelmann N,Kiener H,Sticherling M,Sunderkötter C,Walker UA,Riemekasten G

更新日期：2015-03-01 00:00:00

abstract：:Bone metabolic homeostasis is regulated by a number of hormones and local modulators, and the study of these factors has been of major help in our understanding of bone disease. However, these parameters do not, in a strict sense reflect the metabolic and biochemical changes in the diseased bone tissue. Thus, there is...

journal_title：Zeitschrift fur Rheumatologie

authors： Tohmé JF,Seibel MJ,Silverberg SJ,Robins SP,Bilezikian JP

更新日期：1991-05-01 00:00:00

abstract：:Heavy physical work load is a known determinant of osteoarthritis of the hip, which may account for the high risk observed among farmers. On the other hand, the data on influence of heavy manual work in the pathogenesis of hand osteoarthritis are still controversial. We examined 25 retired farm laborers who strenuousl...

journal_title：Zeitschrift fur Rheumatologie

authors： Schmid L,Dreier D,Muff B,Allgayer B,Schlumpf U

更新日期：1999-12-01 00:00:00

abstract：:The duration and severity of rheumatic diseases of the shoulder correlate with symptom frequency, structural changes and associated functional limitations. The multifactorial character of the underlying rheumatic disease requires a multimodal therapeutic concept including interaction of surgical and non-surgical disci...

journal_title：Zeitschrift fur Rheumatologie

authors： Heers G,Grifka J,Springorum HR,Craiovan B,Anders S

更新日期：2015-11-01 00:00:00

abstract：:This paper concerns a radiological and postmortem study of an 81-year-old woman with diffuse intervertebral osteochondrosis (T12-L1 severe erosion) in association with generalized osteoarthritis and articular chondrocalcinosis. Varying degrees of cartilage plate flaws with cartilaginous Schmorl's nodes and vertebral p...

journal_title：Zeitschrift fur Rheumatologie

authors： Lagier R,Mac Gee W

更新日期：1979-11-01 00:00:00

abstract：:Low back pain (LBP) in patients with rheumatoid arthritis (RA) has so far been of little concern in clinical investigations. The main focus of scientific publications on spinal problems in RA was the cervical spine. In a recent study, we could demonstrate that LBP in RA patients leads to a significantly higher degree ...

journal_title：Zeitschrift fur Rheumatologie

authors： Kothe R

更新日期：2017-12-01 00:00:00

abstract：:Osteoarthritis is the most common joint disease. In addition to known risk factors e.g. genetics, age and hormonal status it has been suggested that chronic-repetitive micro- and substantial (macro-) injury may play an important pathogenetic role. In a longitudinal case-study we examined Judo-players for clinical and ...

journal_title：Zeitschrift fur Rheumatologie

authors： Strasser P,Hauser M,Häuselmann HJ,Michel BA,Frei A,Stucki G

更新日期：1997-12-01 00:00:00

abstract：:In a sequential study the pathogenesis of chronic polyarthritis occurring spontaneously in MRL mice was analysed by light microscopy. A total of 128 MRL mice of both substrains (MRL/Mp-lpr/lpr and +/+) and different age groups was studied. In 50 lpr/lpr mice, tinctorial and histochemical methods were applied for the i...

journal_title：Zeitschrift fur Rheumatologie

authors： Hewicker M,Garcés LH,Kromschröder E,Trautwein G

更新日期：1988-07-01 00:00:00

abstract：:Following the EULAR recommendations published in 2010 German guidelines for the medical treatment of rheumatoid arthritis were developed based on an update of the systematic literature search and expert consensus. Methotrexate is the standard treatment option at the time of diagnosis, preferably in combination with lo...

journal_title：Zeitschrift fur Rheumatologie

authors： Krüger K,Wollenhaupt J,Albrecht K,Alten R,Backhaus M,Baerwald C,Bolten W,Braun J,Burkhardt H,Burmester G,Gaubitz M,Gause A,Gromnica-Ihle E,Kellner H,Kuipers J,Krause A,Lorenz HM,Manger B,Nüßlein H,Pott HG,Rubbert-

更新日期：2012-09-01 00:00:00

abstract：:The case of a 36-year old man with Behçet's disease (BS) for 16 years had low back pain and stiffness in the cervical and lumbar spine. He was diagnosed as having ankylosing spondylitis (AS). In this report we wish to emphasize the clinically occult co-existence of AS in BS and revelation of AS after a long time of BS...

journal_title：Zeitschrift fur Rheumatologie

authors： Cimen OB,Sahin G,Biçer A,Erdoğan C

更新日期：2002-08-01 00:00:00

abstract：:In a twenty-nine year old female patient with progressive systemic sclerosis (scleroderma) (PSS) and an impressing involvement of the intestine (disturbance of the oesophageal motility, pseudo-obstruction, malabsorption) a spontaneous, asymptomatic pneumoperitoneum is observed. Perforation or pneumatosis cystoides int...

journal_title：Zeitschrift fur Rheumatologie

authors： Lang B,Meske S,Billmann P,Vaith P,Peter HH

更新日期：1986-03-01 00:00:00

abstract：:The immune system is regulated by a variety of mechanisms that prevent overwhelming immune responses and a break in tolerance. There have been indications for some time that populations of B cells are also a part of this network and able to exert regulatory functions. Here we summarize current knowledge on this previo...

journal_title：Zeitschrift fur Rheumatologie

authors： Tretter T,Lorenz HM

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Sport is becoming increasingly more important in our society. Due to the changing age spectrum with a greater number of elderly and substantially more active people, an increasing number of people with underlying orthopedic diseases are becoming interested in participating in sport. MATERIAL AND METHODS:Thi...

journal_title：Zeitschrift fur Rheumatologie

authors： Proschek D,Rehart S

更新日期：2014-06-01 00:00:00