[Sensitivity and significance of nuclear magnetic tomography findings of finger joints in rheumatoid arthritis].


:Evaluation of the sensitivity and value of magnetic resonance imaging (MRI) findings and miniarthroscopic investigations (mini-/needle-arthroscopy = MA) of metacarpophalangeal (MCP) joints in patients with rheumatoid arthritis (RA). 30 patients with RA (21 female, 9 male), disease duration 2 months to 22 years and mean disease activity score (DAS) of 3.90 (range: 2.00-7.67) were examined by MRI of the hand (MCP region) and following MA of the MCP-II joints. MRI parameters for arthritis (synovial enhancement, synovial extension, cortical alterations, joint gap width) and corresponding macroscopic items (synovial extension, synovial hyperemia and vascularity, cortical alterations) by MA, scored semiquantitatively for synovitis (graduated from 0-III degree), were correlated. Additionally, normal radiographs of the hands were performed and compared with MRI findings concerning the detection of bony lesions. Evaluation of the 30 MRI and MA examination revealed highly significant correlations (p < 0.0001) for the parameters of synovial extension (MRI/MA), cortical alterations (MRI/MA) and synovial enhancement (MRI) compared to synovial hyperemia and vascularity (MA). We found significant correlations for parameters of activity and chronicity of RA pathology as assessed by MRI and MA. The detection rate of cortical lesions by MRI was two and a half times higher than by X-ray. MRI findings of MCP-II joints compared to those of MCP III-V showed that the MCP-II joint was more strongly involved.


Z Rheumatol


Peters R,Ostendorf B,Scherer A,Becker A,Dann P,Merk H,Mödder U,Schneider M





Has Abstract


2002-04-01 00:00:00












  • [Ocular sarcoidosis].

    abstract::Ocular manifestation of sarcoidosis occurs in up to 60% of patients with confirmed systemic sarcoidosis and represents one of the most common forms of noninfectious uveitis. In known pulmonary sarcoidosis, ocular involvement can occur in up to 80% of cases. Sarcoidosis can also present only in the eye, without a syste...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审


    authors: Springer-Wanner C,Brauns T

    更新日期:2017-06-01 00:00:00

  • [Bone morphogenetic proteins in the skeletal system].

    abstract::Bone morphogenetic proteins (BMPs) belong to the transforming growth factor-beta superfamily. Their potential for organ and tissue regeneration and repair has been intensively investigated in recent years. Studies on fetal development have demonstrated the important role of these proteins for the development and diffe...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审


    authors: Bramlage CP,Häupl T,Kaps C,Bramlage P,Müller GA,Strutz F

    更新日期:2005-09-01 00:00:00

  • [Prophylaxis and treatment of infections in elderly patients with rheumatism].

    abstract::In general, the risk of serious infections increases with age, mainly explained by immunosenescence and accumulation of comorbidities. Those patients with rheumatoid arthritis who are of advanced age and require treatment with immunosuppressive agents are at particular risk to develop an infectious disease. Actual req...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Kneitz C,Strangfeld A,Krüger K

    更新日期:2014-04-01 00:00:00

  • [Pharmacologic characteristics as the basis for differential therapy using non-steroidal anti-inflammatory agents].

    abstract::An attempt is made to compile the pharmacological data on the leading non-steroidal anti-inflammatory drugs. They concern the pharmacodynamics, the pharmacokinetics and the unwanted effects of these compounds. From these data a few suggestions for rational use are made: Ibuprofen and diclofenac present as drugs with s...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Brune K

    更新日期:1987-01-01 00:00:00

  • [Operative treatment of the rheumatic shoulder].

    abstract::The duration and severity of rheumatic diseases of the shoulder correlate with symptom frequency, structural changes and associated functional limitations. The multifactorial character of the underlying rheumatic disease requires a multimodal therapeutic concept including interaction of surgical and non-surgical disci...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审


    authors: Heers G,Grifka J,Springorum HR,Craiovan B,Anders S

    更新日期:2015-11-01 00:00:00

  • [A new measuring device for computer-assisted imaging of the form and flexibility of the spine].

    abstract::Our aim is to present a new method to examine spinal mobility and spine shape excluding torsional scoliosis. In comparison to measuring devices of the spine used so far, this noninvasive and easy to use method documents altered patterns of intervertebral mobility of the lumbar and thoracic spine. This may lead to a br...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Hauns B,Ovenhausen K,Hase P,Lorenzen W,Mennet P,Stratz T,Müller W

    更新日期:1994-05-01 00:00:00

  • [Control of penicillamine therapy in patients with chronic polyarthritis through urine disc electrophoresis].

    abstract::D-penicillamine treatment of 50 patients with rheumatoid arthritis with negative ANF tests, was followed by means of protein disk electrophoresis of the urine. In the beginning the urine proteins were analysed every 4 weeks, later at intervals of 3 to 6 months. A glomerular proteinuria, caused by an immune-complex nep...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Rautenstrauch H

    更新日期:1977-11-01 00:00:00

  • [History of the German Society of Rheumatology 1947-2007].

    abstract::The "German Society of Rheumatology" was founded in Bad Neuenahr in the Federal Republic of Germany In 1947. The society perceived itself as the successor to the "German Society for the Abatement of Rheumatism". The primary aim of the society was close cooperation with other German-speaking rheumatological societies i...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 历史文章,杂志文章


    authors: Hewelt T

    更新日期:2011-01-01 00:00:00

  • [Studies on mobility and prognosis in spondylitis ankylosans].

    abstract::278 patients with ankylosing spondylitis have been studied in order to find a basis for prognosis by setting a mobility function index of the vertebral column. This index does not depend on manifestation age or on the blood sedimentation rate. It increases with progression of x-ray findings. A coincidence of impaired ...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Schöffel J,Pohl W

    更新日期:1975-11-01 00:00:00

  • [Need and possibility for quality management in the rheumatologic specialty practice].

    abstract::In recent years German authorities established a global budget for health care expenditures solely based on macroeconomic aspects. In the last year there have been attempts to define differentiated budgets for chronic diseases. These plans are mainly defined by quality aspects on the process level (creating networks) ...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Karger T

    更新日期:1998-12-01 00:00:00

  • [Histopathogenesis of synovialitis in experimental allergic rabbit arthritis. Comparative studies on rheumatoid synovialitis].

    abstract::The development of synovitis was studied in 64 rabbits with experimentally produced allergic arthritis and in 30 rabbits with experimentally produced non-allergic arthritis. The results are compared with the morphological changes of the synovial membrane in rheumatoid arthritis, especially in early stages, known from ...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Püschel W

    更新日期:1982-01-01 00:00:00

  • [Enteropathic arthritis: water in the intestines, fire in the joints].

    abstract::Patients with various kinds of intestinal illnesses sometimes suffer not only abdominal symptoms, but also joint involvement, leading to a reduction in quality of life. Diseases leading to inflammatory joint involvement such as inflammatory bowel disease, Whipple's disease or surgical intestinal bypass, are classified...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审


    authors: Ronneberger M

    更新日期:2009-06-01 00:00:00

  • [Current aspects of cost effectiveness of TNF-alpha blocking agents in patients with rheumatoid arthritis].

    abstract::Facing increasing health-related costs and limited health care resources, the assessment of cost effectiveness (CE) of medical procedures is also gaining considerable importance in the field of rheumatology. Since high annual therapy costs of 17,000-21,000 Euro are related to the employment of TNF-alpha blocking agent...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审


    authors: Merkesdal S,Ruof J

    更新日期:2002-01-01 00:00:00

  • [How long should treatment with tocilizumab be carried out for giant cell arteritis and how should it be ended (discontinue/taper off)?]

    abstract::The revised S2 guidelines for treatment of giant cell arteritis have recently been published. Glucocorticosteroids remain the standard first line treatment. For severe or relapsing courses of the disease, the IL‑6 antagonist tocilizumab, a potent antibody, is now available as a therapeutic option; however, how long th...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Henes J

    更新日期:2020-12-22 00:00:00

  • [Magnetic resonance tomography and hybrid imaging in rheumatology].

    abstract::In rheumatologic diseases magnet resonance imaging (MRI) is capable of depicting early inflammatory changes which are frequently missed by other imaging modalities. New MRI protocols and hardware, primarily whole-body MRI and low-field extremity MRI facilitate the use of MRI in rheumatology patients. The increasing nu...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审


    authors: Buchbender C,Schneider M,Ostendorf B

    更新日期:2013-03-01 00:00:00

  • [Trends in rehabilitation of patients with rheumatic diseases in Germany].

    abstract::Recent Deutsche Gesellschaft für Rheumatologie (DGRh, German Society of Rheumatology) guidelines emphasized the significance of coordinated multidisciplinary care and rehabilitation of patients with inflammatory rheumatic diseases. Nationwide data from the German pension insurance funds showed that inpatient rehabilit...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Mau W,Beyer W,Ehlebracht-König I,Engel JM,Genth E,Jäckel WH,Lange U,Thiele K

    更新日期:2014-03-01 00:00:00

  • [SAPHO syndrome].

    abstract::The SAPHO syndrome, an acronym for synovitis, acne, pustulosis, hyperostosis and osteitis, is a rare disease which affects bones, joints and the skin. The main osteoarticular features are hyperostosis and osteitis. Osteoarticular symptoms predominantly occur on the anterior chest wall but the spine and the peripheral ...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Heldmann F,Kiltz U,Baraliakos X,Braun J

    更新日期:2014-10-01 00:00:00

  • [Aseptic osteonecrosis after steroid treatment].

    abstract::A 28-year-old female patient had load-dependent pain of the left knee. MRI showed an osteochondral defect of the medial condyle based on extensive osteonecrosis of the femoral and tibial bone. An association with a prior steroid treatment after cervical injury is most likely. ...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Steinhagen J,Rüther W

    更新日期:2004-06-01 00:00:00

  • The coexistence of mutilating rheumatoid arthritis, progressive systemic sclerosis and polycythemia vera--a case report.

    abstract::A 41-year-old patient with mutilating rheumatoid arthritis and progressive systemic sclerosis, who developed a chronic myeloproliferative disorder polycythemia vera was observed. Some of the pathogenetic aspects of this case with special respect to the function abnormalities of peripheral blood polymorphonuclear cells...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Hrycaj P,Mackiewicz S

    更新日期:1992-09-01 00:00:00

  • Prolactin levels and autoantibodies in female patients with systemic lupus erythematosus.

    abstract::We investigated the relationships between prolactin (PRL) levels and antibody occurrence in systemic lupus erythematosus (SLE). No significant association between PRL levels and the majority of the autoantibodies studied (anti-U1 RNP, anti-rRNP, anti-Sm, anti-dsDNA, anti-DNP, auto-LCA, anti-EACA) could be confirmed (P...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Kozáková D,Rovenský J,Cebecauer L,Bosák V,Jahnová E,Vigas M

    更新日期:2000-01-01 00:00:00

  • [Revised version of the statement by the DGRh on biosimilars-update 2017].

    abstract::The treatment of rheumatic diseases with bioloics has significantly improved the prognosis of patients. Currently, there are 13 preparations available in Germany for the treatment of patients with inflammatory rheumatic diseases. These original preparations generally have-depending on the individual country-15 years o...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Braun J,Lorenz HM,Müller-Ladner U,Schneider M,Schulze-Koops H,Specker C,Strangfeld A,Wagner U,Dörner T

    更新日期:2018-02-01 00:00:00

  • [Psychiatric disorders in rheumatic diseases, as exemplified by systemic lupus erythematosus (SLE)].

    abstract::Among the rheumatic diseases, systemic lupus erythematosus (SLE) reveals the highest frequency of central nervous symptoms. Psychiatric abnormalities are present in over 90% of the patients, if very mild cognitive impairment is included. The psychiatric syndromes listed by the American College of Rheumatologists encom...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审


    authors: Haupt M

    更新日期:2004-04-01 00:00:00

  • [Effect of histamine-blocking substances on mitogen-induced lympho proliferation in rheumatic diseases].

    abstract::Peripheral blood lymphocytes of patients with rheumatoid arthritis, psoriatic arthritis and healthy controls, isolated by a ficoll density gradient, were incubated with different concentrations of histamine, cimetidine and diphenhydramine (DPH) and simultaneously stimulated with phytohemagglutinine (PHA). In compariso...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Manger BJ,Stix R,Platzer E,Hess B,Kalden JR

    更新日期:1984-07-01 00:00:00

  • [Measurement of quality of life in patients with active ankylosing spondylitis being treated with infliximab-a comparison of SF-36 and SF-12].

    abstract:BACKGROUND:Quality of life as a part of the WHO definition of health is an important assessment tool for measuring the success in the treatment of chronic diseases. The short form 36 questionnaire (SF-36), which is measuring health related quality of life, was used in a multicentre placebo controlled study in patients ...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Haibel H,Niewerth M,Brandt J,Rudwaleit M,Listing J,Sieper J,Braun J

    更新日期:2004-10-01 00:00:00

  • [Neonatal lupus erythematosus].

    abstract::The neonatal lupus erythematosus syndrome, first described by McCuistion and Schoch in 1954, is associated with characteristic skin lesions and congenital heart block in the new-born, and the presence of Ro-(SSA), La-(SSB), or RNP antibodies in mothers and infants. A transplacental transference of maternal autoantibod...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审


    authors: Mayet WJ,Hermann E,Bachmann M,Poralla T,Meyer zum Büschenfelde KH

    更新日期:1989-03-01 00:00:00

  • [Comparison of glycosaminoglycan polysulfate (Arteparon) and physiological saline solution in arthrosis of the large joints. Results of a multicenter double-blind study].

    abstract::In a double-blind study, glycosaminoglycan polysulfate (GAGPS, Arteparon) was compared to saline solution: both preparations were applied intramuscularly in two groups of 70 patients, each over a period of 8 weeks. The patients were suffering from pain and impaired function of the knee and hip joints. To assess the th...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Siegmeth W,Radi I

    更新日期:1983-07-01 00:00:00

  • [Polyarteritis nodosa: differential diagnostics and therapy].

    abstract::Polyarteritis nodosa (PAN) is a necrotizing vasculitis of medium size arteries that may affect various organs. The clinical appearance is very variable. The most common manifestations are of the skin, the peripheral nervous system presenting as mononeuritis multiplex and the mesenteric and renal blood vessels due to t...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Schirmer JH,Holl-Ulrich K,Moosig F

    更新日期:2014-12-01 00:00:00

  • [Visceral diseases as cause of lumbar syndromes].

    abstract::30 patients with hepatitis, 50 patients with gynecological diseases, and 100 with urological diseases were investigated with regards to lumbago to find out whether there is a correlation between the internal disease and the signs of low back pain. The patients were compared with a control group of 33 healthy people. T...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Tilscher H,Bogner G,Landsiedl F

    更新日期:1977-05-01 00:00:00

  • Orthopädische Rheumatologie.

    abstract:: ...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 新闻



    更新日期:2018-11-01 00:00:00

  • [Imaging procedures in rheumatology: imaging in vasculitis].

    abstract::In small vessel vasculitides, imaging studies aid in determining disease extent and activity, localization for biopsy, and for disease monitoring. They do not directly delineate the vasculitic lesion. Imaging studies focus on the upper and lower respiratory tract. Cranial magnetic resonance imaging (MRI) shows upper r...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章


    authors: Schmidt WA,Both M,Reinhold-Keller E

    更新日期:2006-11-01 00:00:00