Microbiology of destructive periodontal disease in adolescent patients with congenital neutropenia. A report of 3 cases.

Abstract:

BACKGROUND, AIMS:Congenital neutropenia is one condition that may predispose for destructive periodontal disease at a young age. In this report, we describe the microbiology of 3 adolescent patients with congenital neutropenia two of whom suffered from severe periodontitis. METHOD:Microbiological testing of the parents was also performed in 1 case. DNA fingerprinting was used to study transmission of putative periodontal pathogens in this case. From 1 patient with periodontitis, Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis were isolated; a 2nd periodontitis patient was infected with P. gingivalis. A 3rd patient had gingivitis only and no A. actinomycetemcomitans or P. gingivalis were found. RESULTS:Using the amplified fragment length polymorphism DNA fingerprinting technique, bacterial transmission between the father and a patient was shown for A. actinomycetemcomitans but not for P. gingivalis.

journal_name

J Clin Periodontol

authors

van Winkelhoff AJ,Schouten-van Meeteren AY,Baart JA,Vandenbroucke-Grauls CM

doi

10.1034/j.1600-051x.2000.027011793.x

keywords:

subject

Has Abstract

pub_date

2000-11-01 00:00:00

pages

793-8

issue

11

eissn

0303-6979

issn

1600-051X

journal_volume

27

pub_type

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