No detrimental effect of fibrin glue on the regeneration of intrabony defects. A controlled clinical trial.

Abstract:

:This controlled clinical trial evaluated the potential of fibrin glue as a biological carrier to locally deliver guided tissue regeneration (GTR) modulators, 2 controlateral, morphologically similar defects were selected in each of 11 patients and randomly assigned to the test (teflon membrane and fibrin glue) and the control treatment (teflon membrane alone). Outcomes were assessed at membrane removal as newly formed granulation tissue and at the 1-year follow-up in terms of changes in probing attachment level, probing pocket depth, recession of the gingival margin, probing bone levels and percentage of fill of the intrabony defects. Data confirmed that GTR treatment of deep intrabony defects results in clinically and statistically significant improvements of the clinical parameters. No significant differences, however, were evidenced between the test and the control treatments. It is suggested that, since fibrin glue did not show detrimental effects on GTR, it could be applied as a biological carrier for the delivery of GTR enhancers into the surgical wound.

journal_name

J Clin Periodontol

authors

Cortellini P,Pini Prato GP,Tonetti MS

doi

10.1111/j.1600-051x.1995.tb00829.x

subject

Has Abstract

pub_date

1995-09-01 00:00:00

pages

697-702

issue

9

eissn

0303-6979

issn

1600-051X

journal_volume

22

pub_type

临床试验,杂志文章,随机对照试验
  • A study on the imaging of complex furcation forms in upper and lower molars.

    abstract:BACKGROUND, AIMS:The form of the molar roots and their furcated region influence both the pathogenesis of periodontal destruction and therapeutic attempts. METHOD:Using a specially-constructed measuring device, 359 1st and 2nd molars, both upper and lower, were analysed 3-dimensionally. The parameters measured were ho...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1034/j.1600-051x.2000.027012926.x

    authors: Plagmann HC,Holtorf S,Kocher T

    更新日期:2000-12-01 00:00:00

  • Pleiotropic effects of vitamin D3 on CD4+ T lymphocytes mediated by human periodontal ligament cells and inflammatory environment.

    abstract:AIMS:Both, vitamin D3 and human periodontal ligament cells (hPDLCs) possess immunosuppressive properties, but their combined effect on immune cells has never been investigated. Here, we analysed the impact of vitamin D3 on the immunosuppressive properties of hPDLCs towards CD4+ T lymphocytes. MATERIAL AND METHODS:Allo...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.13283

    authors: Behm C,Blufstein A,Gahn J,Kubin B,Moritz A,Rausch-Fan X,Andrukhov O

    更新日期:2020-06-01 00:00:00

  • Characterization of progressive periodontal lesions in chronic periodontitis patients: levels of chemokines, cytokines, matrix metalloproteinase-13, periodontal pathogens and inflammatory cells.

    abstract:BACKGROUND AND AIMS:Periodontitis is an infection with an episodic nature of tissue support destruction. The aim of this work was to determine the levels of chemokines, cytokines, matrix metalloproteinase-13, periodontal pathogens and inflammatory cells in periodontal sites characterized by active periodontal connectiv...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2007.01190.x

    authors: Silva N,Dutzan N,Hernandez M,Dezerega A,Rivera O,Aguillon JC,Aravena O,Lastres P,Pozo P,Vernal R,Gamonal J

    更新日期:2008-03-01 00:00:00

  • Periodontal healing following reconstructive surgery: effect of guided tissue regeneration using a bioresorbable barrier device when combined with autogenous bone grafting. A randomized controlled clinical trial.

    abstract:OBJECTIVE:The objective of this randomized-controlled clinical trial was to evaluate the adjunctive effect of guided tissue regeneration (GTR) using a bioresorbable polylactic acid (PLA) barrier device when combined with autogenous bone grafting in the treatment of deep intra-bony periodontal defects. MATERIAL AND MET...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-051X.2007.01160.x

    authors: Nygaard-Østby P,Bakke V,Nesdal O,Nilssen HK,Susin C,Wikesjö UM

    更新日期:2008-01-01 00:00:00

  • Effects of chlorhexidine on proteolytic and glycosidic enzyme activities of dental plaque bacteria.

    abstract::Chlorhexidine was tested for its ability to inhibit a wide range of glycosidic and proteolytic enzyme activities produced by Treponema denticola, Porphyromonas gingivalis, Bacteroides intermedius, Actinobacillus actinomycemcomitans, Capnocytophaga sputigena, Capnocytophaga gingivalis, Capnocytophaga orchracea, Capnocy...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1991.tb01693.x

    authors: Beighton D,Decker J,Homer KA

    更新日期:1991-02-01 00:00:00

  • Longitudinal study of untreated periodontitis (II). Microbiological findings.

    abstract::11 volunteer subjects with advanced chronic periodontitis participated in a 1-year longitudinal clinical and microbiological study. Subgingival plaque was collected at each of 7 visits from 148 pre-selected sites in the left jaw quadrants (test sites) and on the first and last visits, only from 117 sites in the left j...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1988.tb01592.x

    authors: MacFarlane TW,Jenkins WM,Gilmour WH,McCourtie J,McKenzie D

    更新日期:1988-05-01 00:00:00

  • A comparison of Er:YAG laser and mechanical debridement for the non-surgical treatment of chronic periodontitis: a randomized, prospective clinical study.

    abstract:AIMS:To compare a monotherapy of Er:YAG laser debridement (ERL), wavelength 2940 nm, with mechanical scaling and root planing (SRP) for the treatment of chronic periodontitis using clinical and patient-centred outcomes. METHODS:Twenty-eight participants had two randomly assigned quadrants treated with ERL and two with...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-051X.2012.01873.x

    authors: Soo L,Leichter JW,Windle J,Monteith B,Williams SM,Seymour GJ,Cullinan MP

    更新日期:2012-06-01 00:00:00

  • Is progression of periodontitis relevantly influenced by systemic antibiotics? A clinical randomized trial.

    abstract:AIM:We investigated the long-term impact of adjunctive systemic antibiotics on periodontal disease progression. Periodontal therapy is frequently supplemented by systemic antibiotics, although its impact on the course of disease is still unclear. MATERIAL & METHODS:This prospective, randomized, double-blind, placebo-c...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1111/jcpe.12441

    authors: Harks I,Koch R,Eickholz P,Hoffmann T,Kim TS,Kocher T,Meyle J,Kaner D,Schlagenhauf U,Doering S,Holtfreter B,Gravemeier M,Harmsen D,Ehmke B

    更新日期:2015-09-01 00:00:00

  • Periodontitis and systemic diseases: a record of discussions of working group 4 of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases.

    abstract:BACKGROUND:There has been an explosion in research into possible associations between periodontitis and various systemic diseases and conditions. AIM:To review the evidence for associations between periodontitis and various systemic diseases and conditions, including chronic obstructive pulmonary disease (COPD), pneum...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.12091

    authors: Linden GJ,Herzberg MC,Working group 4 of joint EFP\/AAP workshop.

    更新日期:2013-04-01 00:00:00

  • Intra- and extra-oral halitosis: finding of a new form of extra-oral blood-borne halitosis caused by dimethyl sulphide.

    abstract:AIM:The aim of this study was to unravel the origen and cause of intra-oral and extra-oral halitosis. MATERIAL AND METHODS:We studied 58 patients complaining of halitosis, using gas chromatography of volatile sulphur compounds (VSCs) in mouth and nose breath, organoleptic scoring of mouth and nose breath, Halimeter re...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2007.01116.x

    authors: Tangerman A,Winkel EG

    更新日期:2007-09-01 00:00:00

  • Successive removal of periodontal tissues. Marginal healing without plaque control.

    abstract::The aim of the present study was to compare periodontal healing after successive removal of periodontal tissue components, from the alveolar bone to the dentin surface. The prevailing tissue reaction when adhering PDM was left on the exposed roots was that most of the bone tissue that had been removed from the buccal ...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1993.tb01753.x

    authors: Lindskog S,Lengheden A,Blomlöf L

    更新日期:1993-01-01 00:00:00

  • Healing of the dento-epithelial junction following the use of dental floss.

    abstract::The healing of the dento-epithelial junction following the use of dental floss was studied on 28 first premolars in seven children who were under orthodontic treatment. On the mesial surfaces the floss was brought to the depth of the pocket and moved back and forth three to five times, while being pressed against the ...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1981.tb02354.x

    authors: Waerhaug J

    更新日期:1981-04-01 00:00:00

  • Cost-effectiveness of regular versus irregular supportive periodontal therapy or tooth removal.

    abstract:AIM:For periodontitis patients, regular supportive periodontal therapy (SPT) decreases risks of tooth loss, with savings for tooth replacement possibly compensating SPT-costs. We aimed to assess the cost-effectiveness of regular versus irregular SPT, and to compare both strategies with immediate tooth removal. METHODS...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.12595

    authors: Schwendicke F,Stolpe M,Plaumann A,Graetz C

    更新日期:2016-11-01 00:00:00

  • Ex vivo studies of polymorphonuclear neutrophils from patients with early-onset forms of periodontitis. (I). Chemotactic assessment using the under agarose method.

    abstract::The polymorphonuclear neutrophil (PMN) appears to be an important cell in the protection of the host from pathogenic periodontal microorganisms and, despite some reports to the contrary, it is generally assumed that early-onset forms of periodontal disease (including both juvenile and rapidly progressing periodontitis...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1994.tb00300.x

    authors: Mouynet P,Delamaire M,le Goff MC,Kerbaol M,Yardin M,Michel JF

    更新日期:1994-03-01 00:00:00

  • Relationship of ascorbic acid levels of blood and gingival tissue with response to periodontal therapy.

    abstract::The effect of ascorbic acid megadoses on gingival clinical parameters and vitamin content of blood and gingival tissue was studied. 10 nondeficient individuals, carefully matched according to age, periodontal status, and oral hygiene level, were divided into 2 groups: one received 250 mg q.i.d. of ascorbic acid and th...

    journal_title:Journal of clinical periodontology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-051x.1984.tb01319.x

    authors: Woolfe SN,Kenney EB,Hume WR,Carranza FA Jr

    更新日期:1984-03-01 00:00:00

  • Synergistic effect of maternal obesity and periodontitis on preterm birth in women with pre-eclampsia: a prospective study.

    abstract:AIM:The aim of this study was to investigate if pregnant women with both obesity and periodontitis are more likely to experience preterm birth (PTB) in women with pre-eclampsia (PE) than pregnant women with only obesity or only periodontitis. MATERIALS AND METHODS:The study examined a total of 328 pregnant women at 21...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.12574

    authors: Lee HJ,Ha JE,Bae KH

    更新日期:2016-08-01 00:00:00

  • A comparison of manual and controlled-force attachment-level measurements.

    abstract::This study compared the intra-examiner and inter-examiner error of 2 constant force probes to the reading of a conventional manual probe. 3 examiners made repeated examinations of attachment level using a modified Florida probe and a manual North Carolina probe (read to 1 mm or 0.5 mm); relative attachment level measu...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1997.tb01212.x

    authors: Reddy MS,Palcanis KG,Geurs NC

    更新日期:1997-12-01 00:00:00

  • Antagonists of Wnt/β-catenin signalling in the periodontitis associated with type 2 diabetes and smoking.

    abstract:AIM:This study evaluated the levels of sclerostin (SOST) and Dickkopf (DKK)-1 in the chronic periodontitis (CP) associated with type 2 diabetes (DM) and/or smoking. Relationships between SOST, DDK1, RANKL, OPG, IL-1ß, IL-6 and TNF-α, and pathogens were assessed. MATERIAL AND METHODS:The study population included non-d...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.12854

    authors: Miranda TS,Napimoga MH,Feres M,Marins LM,da Cruz DF,da Silva HDP,Duarte PM

    更新日期:2018-03-01 00:00:00

  • The effect of oral irrigation with a magnetic water treatment device on plaque and calculus.

    abstract::Calculus formation on tooth surfaces is analogous to the formation of lime and scale deposits in plumbing. Magnetic water devices have been shown to significantly reduce scale deposits in industry; therefore an oral irrigator with a magnetic water device may have a similar effect on calculus. To test this hypothesis, ...

    journal_title:Journal of clinical periodontology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1600-051x.1993.tb00366.x

    authors: Watt DL,Rosenfelder C,Sutton CD

    更新日期:1993-05-01 00:00:00

  • The width of radiologically-defined attached gingiva over permanent teeth in children.

    abstract::Several authors have determined clinically the width of attached gingiva (AG) over the deciduous and early permanent dentitions in children. They have noticed that when comparing the width of AG over deciduous teeth to the width of AG over the succeeding newly erupted permanent teeth, a clear diminishing in AG can be ...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1994.tb00784.x

    authors: Saario M,Ainamo A,Mattila K,Ainamo J

    更新日期:1994-11-01 00:00:00

  • Association between periodontitis and anti-cardiolipin antibodies in Buerger disease.

    abstract:AIM:Anti-cardiolipin (CL) antibodies can be induced in Buerger disease (BD), an inflammatory occlusive disorder affecting peripheral blood vessels, in response to bacteria bearing homology to the TLRVYK peptide of a phospholipid-binding plasma protein beta-2-glycoprotein I. TLRVYK homologies are present in Porphyromona...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2009.01467.x

    authors: Chen YW,Nagasawa T,Wara-Aswapati N,Ushida Y,Wang D,Takeuchi Y,Kobayashi H,Umeda M,Inoue Y,Iwai T,Ishikawa I,Izumi Y

    更新日期:2009-10-01 00:00:00

  • Effect of ultrasonic debridement using a chlorhexidine irrigant on circulating levels of lipopolysaccharides and interleukin-6.

    abstract:AIM:Transient bacteraemia and endotoxaemia, and elevated levels of systemic cytokines have been reported following subgingival debridement. This study aimed to investigate the effect of chlorhexidine (CHX) solution on circulating levels of lipopolysaccharide (LPS) and interleukin-6 (IL-6) when used as an irrigant durin...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-051X.2008.01221.x

    authors: Lee MK,Ide M,Coward PY,Wilson RF

    更新日期:2008-05-01 00:00:00

  • The influence of surface free energy and surface roughness on early plaque formation. An in vivo study in man.

    abstract::Previous in vivo studies suggested that a high substratum surface free energy (s.f.e.) and an increased surface roughness facilitate the supragingival plaque accumulation. It is the aim of this clinical trial to explore the "relative" effect of a combination of these surface characteristics on plaque growth. 2 strips,...

    journal_title:Journal of clinical periodontology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-051x.1990.tb01077.x

    authors: Quirynen M,Marechal M,Busscher HJ,Weerkamp AH,Darius PL,van Steenberghe D

    更新日期:1990-03-01 00:00:00

  • Collagen gel and membrane in guided tissue regeneration in periodontal fenestration defects in dogs.

    abstract::The effect of a collagen gel matrix as a submembranous space-maintaining material was evaluated in guided tissue regeneration procedures. In 4 dogs, contralateral surgical circular fenestration defects, 5 mm in diameter, were produced at the midbuccal aspect of the alveolar bone in 8 maxillary canines. Removal of bone...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1996.tb00496.x

    authors: Tal H,Pitaru S,Moses O,Kozlovsky A

    更新日期:1996-01-01 00:00:00

  • Guided tissue regeneration for the treatment of intraosseous defects using a biabsorbable membrane. A controlled clinical study.

    abstract::The aim of this controlled, clinical study was to evaluate guided tissue regeneration using a bioabsorbable membrane in periodontal intraosseous defects. Forty patients, each contributing one defect > or =4 mm in depth participated. The control group (18 individuals) received conventional flap therapy, while the test ...

    journal_title:Journal of clinical periodontology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1600-051x.1998.tb02492.x

    authors: Mayfield L,Söderholm G,Hallström H,Kullendorff B,Edwardsson S,Bratthall G,Brägger U,Attström R

    更新日期:1998-07-01 00:00:00

  • The validity and reproducibility of an oral rating index as a measurement of gingival health care and oral hygiene level in adults.

    abstract::The purpose of this study was to investigate the validity and reproducibility of an oral rating index (ORI) as a conceptual measurement of "gingival health care" level in adults. The study was conducted on 163 patients who received medical examinations and attended for dental checkups at a hospital. The score of the O...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1034/j.1600-051x.2000.027006411.x

    authors: Kawamura M,Fukuda S,Inoue C,Sasahara H,Iwamoto Y

    更新日期:2000-06-01 00:00:00

  • The effect of two commercial antibacterial mouthrinses on plaque growth in vivo.

    abstract::An experimental study was designed to compare the claimed antibacterial effect of Betadine and Blend-a-med Fluid with the known plaque growth inhibiting effect of a 0.2% aqueous solution of chlorhexidine digluconate (Hibitane). Before the test perios for 5 days. During the following week they cleaned their teeth mecha...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1976.tb00038.x

    authors: Saxén L,Harjola O,Ainamo J

    更新日期:1976-11-01 00:00:00

  • One-piece zirconia oral implants for single-tooth replacement: Three-year results from a long-term prospective cohort study.

    abstract:AIM:This 3-year report of a prospective long-term cohort investigation aimed to evaluate the clinical and radiographic outcomes of a one-piece zirconia oral implant for single-tooth replacement. MATERIALS AND METHODS:Sixty-five patients received a 1-stage implant surgery with immediate temporization. Standardized radi...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.12815

    authors: Kohal RJ,Spies BC,Bauer A,Butz F

    更新日期:2018-01-01 00:00:00

  • Mechanical and chemical implant decontamination in surgical peri-implantitis treatment: preclinical "in vivo" study.

    abstract:OBJECTIVE:The aim of the present study was to evaluate the effect of a titanium brush and chemical agents following surgical treatment of experimental peri-implantitis. MATERIAL AND METHODS:Six implants were installed in the mandible of eight beagle dogs (unit of analysis) 3 months after tooth extraction. Experimental...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.12566

    authors: Carral C,Muñoz F,Permuy M,Liñares A,Dard M,Blanco J

    更新日期:2016-08-01 00:00:00

  • Predictive power of various models for longitudinal attachment level change.

    abstract::Several statistical models that have been suggested in the periodontal literature for describing longitudinal attachment level changes, such as the gradual loss, single-burst, multiple-burst, and random walk models as well as other models introduced in this paper are compared by their power to predict future attachmen...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1992.tb00444.x

    authors: Yang MC,Marks RG,Clark WB,Magnusson I

    更新日期:1992-02-01 00:00:00