Ex vivo studies of polymorphonuclear neutrophils from patients with early-onset forms of periodontitis. (I). Chemotactic assessment using the under agarose method.

Abstract:

:The polymorphonuclear neutrophil (PMN) appears to be an important cell in the protection of the host from pathogenic periodontal microorganisms and, despite some reports to the contrary, it is generally assumed that early-onset forms of periodontal disease (including both juvenile and rapidly progressing periodontitis) are associated with a defect in PMN chemotactic behaviour. The purpose of the present study was to examine the peripheral PMN chemotactic behaviour, using the under agarose method, in 4 groups, namely healthy periodontium group (n = 7), gingivitis group (n = 8), early-onset periodontitis group (n = 17) and adult periodontitis group (n = 8). PMN from early-onset periodontitis patients showed normal random and chemotactic locomotory behaviour when compared with those of PMN from subjects of the other groups. No statistically significant difference could be found among the 4 studied groups, with regard to spontaneous and oriented migration.

journal_name

J Clin Periodontol

authors

Mouynet P,Delamaire M,le Goff MC,Kerbaol M,Yardin M,Michel JF

doi

10.1111/j.1600-051x.1994.tb00300.x

subject

Has Abstract

pub_date

1994-03-01 00:00:00

pages

177-83

issue

3

eissn

0303-6979

issn

1600-051X

journal_volume

21

pub_type

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