Dramatic osteonecrosis of the jaw associated with oral bisphosphonates, periodontitis, and dental implant removal.

Abstract:

INTRODUCTION:Osteoporosis affects millions of elderly patients, and anti-resorptive drugs (ARD) such as bisphosphonates (BP) represent the first-line therapy. Despite the benefits related to the use of these medications, osteonecrosis of the jaw is a significant complication in a subset of patients receiving these drugs. CASE PRESENTATION:This report documents a case of dramatic bisphosphonate-related osteonecrosis associated with periodontitis and dental implant removal in an osteoporotic patient treated with per os bisphosphonates for an uninterrupted period of 15 years. CONCLUSION:The aim of this report was to discuss the administration period of BP in the treatment of osteoporosis, the decision-making and clinical management of severe MRONJ and the indications for dental implant placement in these specific patients.

journal_name

J Clin Periodontol

authors

Fernández Ayora A,Herion F,Rompen E,Reginster JY,Magremanne M,Lambert F

doi

10.1111/jcpe.12322

subject

Has Abstract

pub_date

2015-02-01 00:00:00

pages

190-5

issue

2

eissn

0303-6979

issn

1600-051X

journal_volume

42

pub_type

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