Abstract:
:The subcellular targeting of mRNAs encoding myelin proteins to the oligodendrocyte processes is an accepted fact in myelin formation. How these messengers are kept silent during their movement to the subcellular domain where they are turned on remains a mystery. This review focuses on aspects of mRNA targeting and speculates on possible molecular mechanisms for the translational control of myelin-located mRNAs.
journal_name
J Neurosci Resjournal_title
Journal of neuroscience researchauthors
Boccaccio GLdoi
10.1002/1097-4547(20001115)62:4<473::AID-JNR1>3.0.keywords:
subject
Has Abstractpub_date
2000-11-15 00:00:00pages
473-9issue
4eissn
0360-4012issn
1097-4547pii
10.1002/1097-4547(20001115)62:4<473::AID-JNR1>3.0.journal_volume
62pub_type
杂志文章,评审abstract::This study examined the effect of chronic exposure to ethanol and brain-derived neurotrophic factor (BDNF) on the responsiveness of cerebellar granule cells to gamma-aminobutyric acid (GABA). Cerebellar granule cell cultures were chronically exposed to ethanol (100 mM), BDNF (20 ng/ml), or the combination of ethanol a...
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journal_title:Journal of neuroscience research
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journal_title:Journal of neuroscience research
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journal_title:Journal of neuroscience research
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pub_type: 杂志文章
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journal_title:Journal of neuroscience research
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doi:
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更新日期:2010-10-01 00:00:00
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journal_title:Journal of neuroscience research
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abstract::A link between aluminum (Al) exposure and age-related neurological disorders has long been proposed. Although the exact mechanism by which the metal may influence disease processes is unknown, there is evidence that exposure to Al causes an increase in both oxidative stress and inflammatory events. These processes hav...
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journal_title:Journal of neuroscience research
pub_type: 杂志文章
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abstract::Remyelination of the central nervous system in multiple sclerosis patients is often incomplete. Remyelination depends on normal oligodendrogenesis and the differentiation of oligodendrocyte precursor cells (OPC) into mature oligodendrocytes (OL). Inhibitor of DNA binding (ID), a transcription factor, is thought to inh...
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journal_title:Journal of neuroscience research
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更新日期:2004-09-15 00:00:00
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