The development of pain-related behaviour and opioid tolerance after neuropathy-inducing surgery and sham surgery.

abstract：:Pain catastrophizing is associated with enhanced temporal summation of pain (TS-Pain). However, because prior studies have found that pain catastrophizing is not associated with a measure of spinal nociception (nociceptive flexion reflex [NFR] threshold), this association may not result from changes in spinal nocicept...

journal_title：Pain

authors： Rhudy JL,Martin SL,Terry EL,France CR,Bartley EJ,DelVentura JL,Kerr KL

更新日期：2011-04-01 00:00:00

abstract：:The processes of individual adaptation to chronic pain are complex and occur across multiple domains. We examined the social, cognitive, and affective context of daily pain adaptation in individuals with fibromyalgia and osteoarthritis. By using a sample of 260 women with fibromyalgia or osteoarthritis, we examined th...

journal_title：Pain

authors： Sturgeon JA,Zautra AJ,Arewasikporn A

更新日期：2014-02-01 00:00:00

abstract：:The purpose of this study was to assess if the functional activation caused by painful stimuli could be detected with arterial spin labeling (ASL), which is a non-invasive magnetic resonance imaging (MRI) technique for measuring cerebral blood flow (CBF). Because ASL directly measures blood flow, it is well suited to ...

journal_title：Pain

authors： Owen DG,Bureau Y,Thomas AW,Prato FS,St Lawrence KS

更新日期：2008-05-01 00:00:00

abstract：:Pain is a complex human trait. It is likely that the interaction of multiple genes, each with a small individual effect, along with the effect of environmental factors, influences the clinical efficacy of opioids rather than a single gene alone. Polymorphisms in genes coding for the mu-opioid receptor (A118G) and cate...

journal_title：Pain

authors： Reyes-Gibby CC,Shete S,Rakvåg T,Bhat SV,Skorpen F,Bruera E,Kaasa S,Klepstad P

更新日期：2007-07-01 00:00:00

abstract：:We studied the prevalence of chronic pain and long term sensory changes after cosmetic augmentation mammoplasty and the effects of a single i.v. preoperative dose of methylprednisolone 125 mg (n=74), parecoxib 40 mg (n=71), or placebo (n=74). A questionnaire was mailed 6 weeks and 1 year after surgery. Response rate a...

journal_title：Pain

authors： Romundstad L,Breivik H,Roald H,Skolleborg K,Romundstad PR,Stubhaug A

更新日期：2006-09-01 00:00:00

abstract：:Previous evidence supports the utility of the newly developed pain attitudes questionnaire (PAQ) for assessing pain-related stoicism and cautiousness in community-dwelling pain-free adults (Yong et al., 2001). A revised questionnaire (PAQ-R) was examined in the present study to determine the generalizability of psycho...

journal_title：Pain

authors： Yong HH,Bell R,Workman B,Gibson SJ

更新日期：2003-08-01 00:00:00

abstract：:Aiming at developing a new, noninvasive approach to spinal cord neuromodulation, we evaluated whether transcutaneous direct current (DC) stimulation induces long-lasting changes in the central pain pathways in human beings. A double-blind crossover design was used to investigate the effects of anodal direct current (2...

journal_title：Pain

authors： Cogiamanian F,Vergari M,Schiaffi E,Marceglia S,Ardolino G,Barbieri S,Priori A

更新日期：2011-02-01 00:00:00

abstract：:Although calcitonin gene-related peptide (CGRP) has been shown to be elevated in jugular venous blood of adult migraineurs during acute migraine attacks, it remains unknown whether CGRP is increased outside of attacks in jugular or cubital venous blood. The aim of the present study was to compare interictal plasma lev...

journal_title：Pain

authors： Ashina M,Bendtsen L,Jensen R,Schifter S,Olesen J

更新日期：2000-05-01 00:00:00

abstract：:Although cognitive-behavioral therapies (CBT) have been demonstrated to be effective for a variety of chronic pain problems, patients vary in their response and little is known about patient characteristics that predict or moderate treatment effects. Furthermore, although cognitive-behavioral theory posits that change...

journal_title：Pain

authors： Turner JA,Holtzman S,Mancl L

更新日期：2007-02-01 00:00:00

abstract：:Medical case management has improved in the past few decades, changing the dynamic interaction between depression and prevalent medical diseases. It is relevant to describe the comorbidity between depression and medical diseases to further improve the effectiveness of case management. We analyzed the data of adults ag...

journal_title：Pain

authors： Johnson K,Politis MD,Hansen AR,McKenzie LE,Duncan DT,Zhang J

更新日期：2017-04-01 00:00:00

abstract：:Thirty subjects were given a placebo (intravenous saline), which was described as a known pain killer, once a week for 3 consecutive weeks. Experimental ischemic arm pain was produced prior to the placebo and again 1 h later. In a double blind procedure, half of the subjects received 10 mg of naloxone after placebo; t...

journal_title：Pain

authors： Grevert P,Albert LH,Goldstein A

更新日期：1983-06-01 00:00:00

abstract：:A controlled clinical trial on the efficacy of a nortriptyline-fluphenazine combination was carried out in patients with painful diabetic polyneuropathy. A visual analog scale was used to evaluate the relief of pain or paresthesia. Significant relief of both pain and paresthesia was obtained with this combination. The...

journal_title：Pain

authors： Gomez-Perez FJ,Rull JA,Dies H,Rodriguez-Rivera GJ,Gonzalez-Barranco J,Lozano-Castañeda O

更新日期：1985-12-01 00:00:00

abstract：:The analgesic efficacy of single doses of oral morphine sulphate solution (10 mg) and ibuprofen 600 mg was compared in 12 volunteers using a double-blind, double-dummy, placebo-controlled design on the cold pressor experimental pain model. Measurement of pain intensity was made before medication and then at 30, 60, 90...

journal_title：Pain

authors： Jones SF,McQuay HJ,Moore RA,Hand CW

更新日期：1988-08-01 00:00:00

abstract：:Although conduction failure has been observed in nociceptive C-fibers, little is known regarding its significance or therapeutic potential. In a previous study, we demonstrated that C-fiber conduction failure, which is regarded as an intrinsic self-inhibition mechanism, was reduced in circumstances of painful diabetic...

journal_title：Pain

authors： Wang X,Wang S,Wang W,Duan J,Zhang M,Lv X,Niu C,Tan C,Wu Y,Yang J,Hu S,Xing J

更新日期：2016-10-01 00:00:00

abstract：:The role of proinflammatory cytokines in neuropathic and inflammatory pain is well established. Recent studies suggest that cytokines such as tumor necrosis factor-alpha (TNF) may also be involved in the development of muscle pain. To investigate the pathophysiology of intramuscular TNF, exogenous TNF (0.1-10 microg),...

journal_title：Pain

authors： Schäfers M,Sorkin LS,Sommer C

更新日期：2003-08-01 00:00:00

abstract：:Tolerance to morphine-induced analgesia is an intractable phenomenon, often hindering its prolonged applications in the clinics. The enhanced pronociceptive actions of spinal pain-related molecules such as calcitonin gene-related peptide (CGRP) may underlie this phenomenon and could be a promising target for intervent...

journal_title：Pain

authors： Wang Z,Ma W,Chabot JG,Quirion R

更新日期：2010-10-01 00:00:00

abstract：ABSTRACT:Morphine-induced alterations in sphingolipid metabolism in the spinal cord and increased formation of the bioactive sphingolipid metabolite sphingosine-1-phosphate (S1P) have been implicated in the development of morphine-induced hyperalgesia (OIH; increased pain sensitivity) and antinociceptive tolerance. The...

journal_title：Pain

authors： Doyle TM,Janes K,Chen Z,Grace PM,Esposito E,Cuzzocrea S,Largent-Milnes TM,Neumann WL,Watkins LR,Spiegel S,Vanderah TW,Salvemini D

更新日期：2020-09-01 00:00:00

abstract：:The objective of this preliminary study was to examine the extent to which affective marital interaction related to depressive symptoms in persons with chronic pain and their spouses and to pain severity in persons with pain. Couples from the community completed self-report surveys and engaged in a videotaped conversa...

journal_title：Pain

authors： Johansen AB,Cano A

更新日期：2007-11-01 00:00:00

abstract：:Extracellular signal-regulated kinase (ERK), a mitogen-activated protein kinases (MAPK), transduces a broad range of extracellular stimuli into diverse intracellular responses. Recent studies have showed that ERK activation in the supraspinal level involved in the development of drug dependence, especially in psycholo...

journal_title：Pain

authors： Cao JL,He JH,Ding HL,Zeng YM

更新日期：2005-12-05 00:00:00

abstract：:There are contradictory findings about whether there are differences in personality and/or amount of emotional disturbance between patients with functional versus organic low back pain. The MMPI scores of 42 back pain patients diagnosed as "organic" were compared with the scores of 37 patients classified as "functiona...

journal_title：Pain

authors： McCreary C,Turner J,Dawson E

更新日期：1977-10-01 00:00:00

abstract：:Heat and electrical detection thresholds were assessed in 72 patients suffering from painful temporomandibular disorder. Employing widely accepted criteria, 44 patients were classified as suffering from temporomandibular joint (TMJ) arthralgia (i.e. pain originating from the TMJ) and 28 from myalgia (i.e. pain origina...

journal_title：Pain

authors： Eliav E,Teich S,Nitzan D,El Raziq DA,Nahlieli O,Tal M,Gracely RH,Benoliel R

更新日期：2003-08-01 00:00:00

abstract：:The perception of pain is highly variable. It depends on bottom-up-mediated factors like stimulus intensity and top-down-mediated factors like expectations. In the brain, pain is associated with a complex pattern of neuronal responses including evoked potentials and induced responses at alpha and gamma frequencies. Al...

journal_title：Pain

authors： Tiemann L,May ES,Postorino M,Schulz E,Nickel MM,Bingel U,Ploner M

更新日期：2015-02-01 00:00:00

abstract：:VGF (nonacronymic) is a granin-like protein that is packaged and proteolytically processed within the regulated secretory pathway. VGF and peptides derived from its processing have been implicated in neuroplasticity associated with learning, memory, depression, and chronic pain. In sensory neurons, VGF is rapidly incr...

journal_title：Pain

authors： Fairbanks CA,Peterson CD,Speltz RH,Riedl MS,Kitto KF,Dykstra JA,Braun PD,Sadahiro M,Salton SR,Vulchanova L

更新日期：2014-07-01 00:00:00

abstract：:The present study examined the role of spinal cholinergic modulation of spinal mechanical and thermal transmission. Intrathecal administration of the cholinergic muscarinic receptor antagonists atropine or scopolamine in awake rats produced a dose-dependent decrease in the nociceptive mechanical withdrawal threshold o...

journal_title：Pain

authors： Zhuo M,Gebhart GF

更新日期：1991-08-01 00:00:00

abstract：:Although it is well known that cannabinoids produce antinociception in acute pain models, there is less information on the ability of cannabinoids to alleviate hyperalgesia. In the present study, we determined whether cannabinoids attenuated the development of hyperalgesia produced by intraplantar injection of capsaic...

journal_title：Pain

authors： Li J,Daughters RS,Bullis C,Bengiamin R,Stucky MW,Brennan J,Simone DA

更新日期：1999-05-01 00:00:00

abstract：:This open prospective study evaluated the combination of initial dose titration with patient-controlled analgesia (PCA) and long-term treatment with transdermal fentanyl in 50 cancer patients requiring opioids for severe pain. The delivery rate of the first transdermal therapeutic system (TTS) was calculated from the ...

journal_title：Pain

authors： Grond S,Zech D,Lehmann KA,Radbruch L,Breitenbach H,Hertel D

更新日期：1997-01-01 00:00:00

abstract：:Injection of a dilute solution of formalin into a rat hindpaw produces a biphasic nociceptive response consisting of an early phase during the first 5 min after formalin injection and a later phase starting after 15 min and lasting for 40-50 min. The period between the two phases of nociceptive responding is generally...

journal_title：Pain

authors： Henry JL,Yashpal K,Pitcher GM,Coderre TJ

更新日期：1999-07-01 00:00:00

abstract：:The significance of preamputation pain for the development of postamputation stump and phantom pain has been discussed over the years and is still a matter of dispute. It has been argued that preamputation pain increases the risk of phantom pain and that phantom pain is a revivification of pain experienced before the ...

journal_title：Pain

authors： Nikolajsen L,Ilkjaer S,Krøner K,Christensen JH,Jensen TS

更新日期：1997-09-01 00:00:00

abstract：:Preliminary reports have shown that hyperbaric oxygen (HBO) interrupts cluster headache (CH) attacks. In the present study, 6 of 7 patients with episodic cluster headache who were treated with hyperbaric oxygen experienced an interruption of the attack. In 3 of 6 responders the florid period of the cluster headache wa...

journal_title：Pain

authors： Di Sabato F,Fusco BM,Pelaia P,Giacovazzo M

更新日期：1993-02-01 00:00:00

abstract：:Dysfunction in the motor system is a feature of persistent whiplash associated disorders. Little is known about motor dysfunction in the early stages following injury and of its progress in those persons who recover and those who develop persistent symptoms. This study measured prospectively, motor system function (ce...

journal_title：Pain

authors： Sterling M,Jull G,Vicenzino B,Kenardy J,Darnell R

更新日期：2003-05-01 00:00:00