Abstract：
:Pain catastrophizing is associated with enhanced temporal summation of pain (TS-Pain). However, because prior studies have found that pain catastrophizing is not associated with a measure of spinal nociception (nociceptive flexion reflex [NFR] threshold), this association may not result from changes in spinal nociceptive processes. The goal of the present study in healthy participants was to examine the relationship between trait (traditional) and state (situation-specific) pain catastrophizing and temporal summation of NFR (TS-NFR) and TS-Pain. A secondary goal was to replicate prior findings concerning relationships between catastrophizing and NFR threshold, electrocutaneous pain threshold, and sensory and affective ratings of electrocutaneous stimuli. All analyses controlled for depression symptoms, pain-related anxiety, and participant sex. As expected, multiple regression analyses indicated that neither trait nor situation-specific catastrophizing was associated with NFR threshold, but that situation-specific catastrophizing was associated with pain ratings. Multilevel linear growth models of TS data indicated that situation-specific catastrophizing was associated with TS-Pain but not TS-NFR. Trait catastrophizing was not related to TS-Pain or TS-NFR. Together, these results confirm prior studies that indicate that catastrophizing enhances pain via supraspinal processes rather than spinal processes. Moreover, because catastrophizing was associated with TS-Pain but not TS-NFR, caution is warranted when using pain ratings to infer temporal summation of spinal nociceptive processes.
journal_name
Painjournal_title
Painauthors
Rhudy JL,Martin SL,Terry EL,France CR,Bartley EJ,DelVentura JL,Kerr KLdoi
10.1016/j.pain.2010.12.041subject
Has Abstractpub_date
2011-04-01 00:00:00pages
794-801issue
4eissn
0304-3959issn
1872-6623pii
00006396-201104000-00016journal_volume
152pub_type
杂志文章相关文献
PAIN文献大全abstract：:Capsaicin elicits burning pain via the activation of the vanilloid receptor (TRPV1). Intriguingly, several reports showed that capsaicin also inhibits Na+ currents but the mechanisms remain unclear. To explore this non-TRPV1 action we applied capsaicin to HEK293 cells stably expressing inactivation-deficient rat skele...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2006.08.002
更新日期：2007-01-01 00:00:00
abstract：:A young female outpatient experienced painful tonic contractions in the right triceps surae muscles as a result of a partial damage of the right peroneal nerve. Electrophysiological recordings of the soleus muscle showed a tonic EMG activity and an hyperexcitability of the monosynaptic H reflex (Hmax/Mmax ratio: 90%)....
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(88)90037-1
更新日期：1988-03-01 00:00:00
abstract：:There is extensive evidence that spinal excitatory amino acids (EAAs) like glutamate (Glu) and aspartate (Asp) are important in the processing of nociceptive behaviors caused by incisions. To better understand EAA-induced dorsal horn sensitization caused by surgery, we examined the time course and extent of spinal ami...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(02)00241-5
更新日期：2002-11-01 00:00:00
abstract：:(1) Capsaicin solution was applied for 15 min around a 1 cm length of sciatic nerve in the mid upper leg of adult rats. (2) Electron microscopic examinations of the nerve in the treated region after 14 days shows no signs of degeneration of either myelinated or unmyelinated fibres attributable to the capsaicin. (3) Fl...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(81)90637-0
更新日期：1981-12-01 00:00:00
abstract：:Anecdotal reports suggest that the general anaesthetic drug ketamine, taken orally in low doses, can give rise to some extra analgesia in patients with refractory neuropathic pain. This study was designed to determine the proportion of patients with chronic neuropathic pain responding to oral ketamine, and then to sep...
journal_title：Pain
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0304-3959(99)00117-7
更新日期：1999-11-01 00:00:00
abstract：:Measurement of depression and other mood states in pain patients has been criticised in recent years on the grounds that most questionnaires were not developed in pain populations and suffer from criterion contamination by somatic items. In addition, there is no accepted measurement for positive emotions which are mor...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2004.02.004
更新日期：2004-05-01 00:00:00
abstract：:The present study observed the expression of the 5-hydroxytryptamine (5-HT) (1A) receptor mRNA in the lumbar spinal dorsal horn neurons following carrageenan inflammation using in situ hybridization (ISH). We also studied the co-localization of 5-HT(1A) receptor mRNA and gamma-amino butyric acid (GABA) or enkephalin (...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(02)00026-X
更新日期：2002-08-01 00:00:00
abstract：:Although trigeminal neuralgia and atypical facial pain can usually be distinguished on the basis of several well-established criteria, differential diagnosis is difficult in a small number of patients. The purpose of this study was to determine whether the McGill Pain Questionnaire (MPQ) is capable of discriminating b...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(86)90157-0
更新日期：1986-12-01 00:00:00
abstract：:Surgery and trauma are recognised as important causes of chronic pain, although their overall contribution has not been systematically studied. This paper reports on the contribution of surgery and trauma to chronic pain among 5130 patients attending 10 outpatient clinics located throughout North Britain. Surgery cont...
journal_title：Pain
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：:Monoclonal antibodies against GD(2) ganglioside, such as ch14.18, the human-mouse chimeric antibody, have been shown to be effective for the treatment of neuroblastoma. However, treatment is associated with generalized, relatively opiate-resistant pain. We investigated if a point mutation in ch14.18 antibody (hu14.18K...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2010.01.024
更新日期：2010-04-01 00:00:00
abstract：:Intraoral somatosensory sensitivity in patients with atypical odontalgia (AO) has not been investigated systematically according to the most recent guidelines. The aims of this study were to examine intraoral somatosensory disturbances in AO patients using healthy subjects as reference, and to evaluate the percent agr...
journal_title：Pain
pub_type： 杂志文章,多中心研究
doi：10.1016/j.pain.2013.04.005
更新日期：2013-08-01 00:00:00
abstract：:Eight patients with established lower limb postamputation stump pain were given lumbar intrathecal fentanyl 25 micrograms and lidocaine 70 mg 2 weeks apart in an attempt to better understand the role of peripheral and central mechanisms in this condition. Baseline pain was recorded and then analgetic and side effects ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(90)90064-K
更新日期：1990-02-01 00:00:00
abstract：:Wind-up and secondary hyperalgesia both are related to central sensitization, but whereas the former is explained by homosynaptic facilitation, the latter is due to heterosynaptic facilitation. To investigate possible interactions between both types of facilitation, we tested for alterations of perceptual wind-up in t...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(97)00177-2
更新日期：1998-02-01 00:00:00
abstract：:Pregnant women may take nonsteroidal antiinflammatory drugs (NSAIDs), selective cyclooxygenase (COX)-2 inhibitors, or biological agents to relieve symptoms or manage disease flares in late pregnancy. We aimed to quantify the risk of prematurity associated with late pregnancy exposure to nonselective NSAIDs, selective ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000001163
更新日期：2018-05-01 00:00:00
abstract：:The present paper describes the effect of vibratory stimulation on pain of dental origin in 36 patients. The patients were from a clinic for dental surgery and all had suffered pain from pulpal inflammation, apical periodontitis or postoperative pain following extraction of an impacted wisdom tooth for more than 2 day...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(81)90043-9
更新日期：1981-02-01 00:00:00
abstract：:G-protein coupled inwardly rectifying potassium (GIRK) channels are effectors determining degree of analgesia experienced upon opioid receptor activation by endogenous and exogenous opioids. The impact of GIRK-related genetic variation on human pain responses has received little research attention. We used a tag singl...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2013.08.026
更新日期：2013-12-01 00:00:00
abstract：:Investigating protective strategies against chronic neuropathic pain (CNP) after breast cancer surgery entails using valid screening tools. The DN4 (Douleur Neuropathique en 4 questions) is 1 tool that offers important research advantages. This prospective 6-month follow-up study seeks to validate the DN4 and assess i...
journal_title：Pain
pub_type： 杂志文章,随机对照试验
doi：10.1097/j.pain.0000000000000108
更新日期：2015-04-01 00:00:00
abstract：:In recent years, oxytocin has been implicated in a wide diversity of functions. The role of oxytocin in analgesia and pain modulation represents an important new function of an endogenous system controlling sensorial information. The paraventricular (PV) nucleus of the hypothalamus is one of the most important sources...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2006.01.029
更新日期：2006-05-01 00:00:00
abstract：:Pain is processed in multiple cortical and subcortical brain areas. Subcortical structures are substantially involved in different processes that are closely linked to pain processing, e.g. motor preparation, autonomic responses, affective components and learning. However, it is unclear to which extent nociceptive inf...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(02)00157-4
更新日期：2002-09-01 00:00:00
abstract：:Tolerance to the antinociceptive (analgesic) effect of morphine, a mu-opioid agonist, was developed in male CD-1 mice as assessed by a shift to the right of the analgesic (tail-flick) dose-response curves and an increase in the ED50 values. Administration of dextromethorphan at 30 mg/kg s.c., but not saline, 30 min pr...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(94)90022-1
更新日期：1994-12-01 00:00:00
abstract：:Forty patients with cancer pain receiving intermittent narcotics were admitted to a prospective study designed to assess the cognitive effects of narcotics. Twenty patients had undergone no change in narcotic dose or type greater than or equal to 7 days (stable dose, SD, group), and 20 patients had undergone an increa...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(89)90169-3
更新日期：1989-10-01 00:00:00
abstract：:This study compared individuals with fibromyalgia (FM) and individuals with chronic low back pain (CLBP) on repetition-induced summation of activity-related pain (RISP). Fear of movement, pain catastrophizing and depression were examined as potential mediators of group differences. The sample consisted of 50 women wit...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2011.02.030
更新日期：2011-06-01 00:00:00
abstract：:Nonopioid agents, such as nonsteroidal anti-inflammatory drugs (NSAIDs), are the most commonly used class of analgesics. Increasing evidence suggests that cyclooxygenase (COX) inhibition at both peripheral and central sites can contribute to the antihyperalgesic effects of NSAIDs, with the predominant clinical effect ...
journal_title：Pain
pub_type： 杂志文章,随机对照试验
doi：10.1097/j.pain.0000000000000176
更新日期：2015-07-01 00:00:00
abstract：:Microglia-neuron signalling in the spinal cord is a key mediator of mechanical allodynia caused by peripheral nerve injury. We recently reported sex differences in microglia in pain signalling in mice: spinal mechanisms underlying nerve injury-induced allodynia are microglial dependent in male but not female mice. Whe...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000001265
更新日期：2018-09-01 00:00:00
abstract：:This study examined the adaptational classification stability of the multidimensional pain inventory (MPI) in two samples of female fibromyalgia syndrome patients. Retest resulted in one-third of patients being assigned to a different classification. Twenty patients had four repeated MPI assessments over a 10-month pe...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2004.01.014
更新日期：2004-05-01 00:00:00
abstract：:Venlafaxine hydrochloride (Effexor) is a structurally novel antidepressant that inhibits reuptake of 5-hydroxytryptamine and noradrenaline, but unlike the older antidepressants, has few side-effects. The objective of this study was to determine whether venlafaxine relieves thermal hyperalgesia in rats with neuropathic...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(96)03223-X
更新日期：1996-11-01 00:00:00
abstract：:Unlike most classical analgesics, botulinum toxin type A (BoNT/A) does not alter acute nociceptive thresholds, and shows selectivity primarily for allodynic and hyperalgesic responses in certain pain conditions. We hypothesized that this phenomenon might be explained by characterizing the sensory neurons targeted by B...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2014.04.027
更新日期：2014-08-01 00:00:00
abstract：:Many treatments used for women with vulvodynia are based solely upon expert opinion. This randomized trial aimed to test the relative efficacy of cognitive-behavioral therapy (CBT) and supportive psychotherapy (SPT) in women with vulvodynia. Of the 50 participants, 42 (84%) completed 10-week treatments and 47 (94%) co...
journal_title：Pain
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.pain.2008.09.031
更新日期：2009-01-01 00:00:00
abstract：:This study critically examines the reported exercise-induced analgesia effect in view of the potential stress-induced analgesia of pain testing itself. Two designs were used to test whether previous findings of analgesia were induced by the exercise procedures or by the stress of the pain testing procedures themselves...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(92)90048-G
更新日期：1992-02-01 00:00:00
abstract：:A survey of the psychological characteristics of a large sample of chronic headache cases (n = 360), including classical and common migraine and tension headache sufferers, was carried out. Comparing groups defined in terms of the chronicity of their headache problems, it was found that those with a longer history of ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(85)90286-6
更新日期：1985-02-01 00:00:00
