Abstract：
:This study compared individuals with fibromyalgia (FM) and individuals with chronic low back pain (CLBP) on repetition-induced summation of activity-related pain (RISP). Fear of movement, pain catastrophizing and depression were examined as potential mediators of group differences. The sample consisted of 50 women with FM and 50 women with CLBP who were matched on age, pain severity and pain duration. Participants were asked to lift a series of 18 weighted canisters. In one trial, participants were asked to rate their pain after each lift. In a second trial, participants estimated the weight of each of the canisters. An index of repetition-induced summation of pain was derived as the change in pain ratings across repeated lifts. Analyses revealed that women with FM obtained higher scores on the index of RISP than women with CLBP. The heightened sensitivity to RISP in individuals with FM was not due to generalized hyperalgesia or a greater work output. Consistent with previous research, fear of movement was positively correlated with RISP. Pain disability was also associated with greater RISP, but not pain catastrophizing or depression. Discussion addresses the processes by which individuals with FM might have increased RISP responses. The findings of this study point to possible neurophysiological mechanisms that could help explain the high levels of pain-related disability seen in individuals with FM. Patients with fibromyalgia showed greater activity-related summation of pain than patients with chronic low back pain.
journal_name
Painjournal_title
Painauthors
Lambin DI,Thibault P,Simmonds M,Lariviere C,Sullivan MJLdoi
10.1016/j.pain.2011.02.030subject
Has Abstractpub_date
2011-06-01 00:00:00pages
1424-1430issue
6eissn
0304-3959issn
1872-6623pii
00006396-201106000-00031journal_volume
152pub_type
杂志文章相关文献
PAIN文献大全abstract：:The facial expression of pain plays a crucial role in pain communication and pain diagnostics. Despite its importance, it has remained unknown which dimensions of pain (sensory and/or affective) are encoded in the face. To answer this question, we used a well-established cognitive strategy (suggestions) to differentia...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2011.10.027
更新日期：2012-02-01 00:00:00
abstract：:Adrenal medullary transplants in the spinal subarachnoid space, by providing a continual source of opioid peptides and catecholamines, offer a potentially important adjunct in the management of chronic pain. While previous studies have shown that this approach is effective against high-intensity phasic stimuli, adrena...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(93)90135-C
更新日期：1993-02-01 00:00:00
abstract：:Chronic dry eye disease (DE) is associated with an unstable tear film and symptoms of ocular discomfort. The characteristics of symptoms suggest a key role for central neural processing; however, little is known about central neuroplasticity and DE. We used a model for tear deficient DE and assessed effects on eye bli...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000000135
更新日期：2015-05-01 00:00:00
abstract：:The roles of central protein kinases A and C (PKA and PKC) in various pain states have intensively been investigated during the past decade. The aim of the present study was to investigate the peripheral involvement of PKA and PKC in persistent nociceptive response, evoked pain behaviors, and inflammation induced by s...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2007.04.040
更新日期：2008-03-01 00:00:00
abstract：:The existence of prostaglandin (PG) receptors in the spinal cord has been demonstrated, but their role in sensory processing is not yet well defined. PGE1 is widely used clinically as a vasodilator. The present study was designed to investigate the effects of intrathecally administered PGE1 on the transmission of diff...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(95)00055-0
更新日期：1995-12-01 00:00:00
abstract：:Hindlimb pain models developed in rats have been transposed to mice, but assumed sciatic nerve neuroanatomic similarities have not been examined. We compared sciatic nerve structural organization in mouse strains (C57BL/6J, DBA/2J, and B6129PF2/J) and rat strains (Wistar, Brown Norway, and Sprague-Dawley). Dissection ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2008.01.016
更新日期：2008-05-01 00:00:00
abstract：:Substance P (SP) plays a central role in the transduction of second messenger signals from primary afferent nociceptive terminals to second-order neurons in the spinal cord. We have tested a recombinant engineered diphtheria toxin/SP fusion protein (DAB389SP) in acute and chronic pain models in the rat. DAB389SP binds...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(98)00170-5
更新日期：1999-02-01 00:00:00
abstract：:Evidence of the relationship between childhood abuse and pain problems in adulthood has been based on cross-sectional studies using retrospective self-reports of childhood victimization. The objective of the current study was to determine whether childhood victimization increases risk for adult pain complaints, using ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(01)00270-6
更新日期：2001-05-01 00:00:00
abstract：:Venlafaxine hydrochloride (Effexor) is a structurally novel antidepressant that inhibits reuptake of 5-hydroxytryptamine and noradrenaline, but unlike the older antidepressants, has few side-effects. The objective of this study was to determine whether venlafaxine relieves thermal hyperalgesia in rats with neuropathic...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(96)03223-X
更新日期：1996-11-01 00:00:00
abstract：:Visceral inflammation is thought to play an important role in the sensitization of low and high threshold mechanosensory and polymodal afferents and to recruit silent nociceptors. Yet, little is known about the potential role of the mediators involved in nociceptor sensitization to mechanical stimulation as compared t...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(01)00318-9
更新日期：2001-09-01 00:00:00
abstract：:The aims of this study were two-fold: first, to simplify the method for creating a recently described neuropathic pain model in the rat, and second, to evaluate the effects of a number of drugs with analgesic or antihyperalgesic properties, in this model. Continuous intravenous vincristine infusion (1-100 microg kg(-1...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(01)00294-9
更新日期：2001-07-01 00:00:00
abstract：:This study critically examines the reported exercise-induced analgesia effect in view of the potential stress-induced analgesia of pain testing itself. Two designs were used to test whether previous findings of analgesia were induced by the exercise procedures or by the stress of the pain testing procedures themselves...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(92)90048-G
更新日期：1992-02-01 00:00:00
abstract：:We developed a mouse model of cancer pain to investigate its underlying mechanisms. SCC-7, squamous cell carcinoma (SCC) derived from C3H mice, was inoculated subcutaneously into either the plantar region or thigh in male C3H/Hej mice. Heat and mechanical sensitivity as well as spontaneous behavior were measured at th...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2005.05.010
更新日期：2005-09-01 00:00:00
abstract：:The purpose of this study was to investigate the mechanisms of referred pain observed in female patients with pain from the reproductive organs. We developed a model of inflammatory uterine pain in the rat. Inflammation of the uterus in rats pretreated with Evans Blue Dye resulted in dye extravasation in the skin over...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(97)00112-7
更新日期：1997-12-01 00:00:00
abstract：:Noradrenaline increases thermal hyperalgesia in skin previously sensitized by capsaicin. The aim of the present study was to determine whether a vasoconstrictor ischaemic effect of noradrenaline increases thermal hyperalgesia. Heat pain thresholds were measured in the capsaicin-treated and untreated skin on the forear...
journal_title：Pain
pub_type： 临床试验,杂志文章
doi：10.1016/0304-3959(96)03115-6
更新日期：1996-09-01 00:00:00
abstract：:The L5 spinal nerve ligation model of neuropathic pain in rats has been proposed as a model for sympathetically maintained pain (SMP) based on the effects of surgical or chemical sympathectomy on nerve injury induced behavior. In an attempt to confirm that the lesion produces an animal model of SMP, surgical sympathec...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(98)00186-9
更新日期：1999-02-01 00:00:00
abstract：:The present study examined the relationship between depression and a constellation of pain-related variables that describe the experience of chronic pain patients. Thirty-seven depressed and 32 non-depressed heterogeneous chronic pain patients were identified through structured interviews, use of standardized criteria...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(91)90073-7
更新日期：1991-08-01 00:00:00
abstract：:The aim of the present study was to investigate changes in the plasma calcitonin gene-related peptide (CGRP) concentration and platelet serotonin (5-hydroxytriptamine, 5-HT) content during the immediate headache and the delayed genuine migraine attack provoked by nitroglycerin. Fifteen female migraineurs (without aura...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2003.09.008
更新日期：2003-12-01 00:00:00
abstract：:Chronic pain is gender-related, since there is a clear predominance of one sex with respect to the other in most pain syndromes. Gonadal hormones are known to affect the occurrence and incidence of pain. Transsexuals receive cross-sex hormones to develop and maintain somatic characteristics of the opposite sex: male t...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2007.02.006
更新日期：2007-11-01 00:00:00
abstract：:Physicians are frequently called upon to evaluate patients with chronic pain to (1) establish the etiology, (2) determine the extent of impairment and disability, and (3) prescribe treatment. In many cases, there is little agreement as to what evaluation procedures should be used or how to weight and integrate these f...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(88)90181-9
更新日期：1988-07-01 00:00:00
abstract：:Using the circumplex model of interpersonal behavior [Handbook of research methods in clinical psychology, 1982], this study tested the communal coping model of catastrophizing (CCM) in a large (N = 179) sample of patients with irritable bowel syndrome (IBS), a common, benign chronic pain disorder associated with sign...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2004.04.011
更新日期：2004-08-01 00:00:00
abstract：:Chronic pain often interferes with daily functioning, and may become a threat to an individual's sense of self. Despite the development of a recent theoretical account focussing upon the relationship between the presence of chronic pain and a person's self, research investigating this idea is limited. In the present s...
journal_title：Pain
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.pain.2013.07.055
更新日期：2013-12-01 00:00:00
abstract：:This study compared a remote-delivered pain management program, the Pain Course, when delivered in online and workbook formats. Participants (n = 178) were randomised into 2 groups: (1) an Internet Group (n = 84) who were provided with secure accounts to the program in an online format; or (2) a Workbook Group (n = 94...
journal_title：Pain
pub_type： 杂志文章,随机对照试验
doi：10.1097/j.pain.0000000000000916
更新日期：2017-07-01 00:00:00
abstract：:The results of two experiments show that ratio scales of sensory and affective verbal pain descriptors are valid, reliable and objective. In the first experiment, 16 subjects rated 15 sensory and 15 affective verbal pain descriptors by numerical magnitude estimation and by cross-modality matching to handgrip force. Ra...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(78)90020-9
更新日期：1978-06-01 00:00:00
abstract：:Immune activation near healthy peripheral nerves may have a greater role in creating pathological pain than previously recognized. We have developed a new model of sciatic inflammatory neuritis to assess how such immune activation may influence somatosensory processing. The present series of experiments reveal that zy...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(01)00354-2
更新日期：2001-12-01 00:00:00
abstract：:Fear-avoidance beliefs have been identified as an important psychosocial variable in patients with chronic disability doe to low back pain. The importance of fear-avoidance beliefs for individuals with acute low back pain has not been explored. Seventy-eight subjects with work-related low back pain of less than 3 week...
journal_title：Pain
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/S0304-3959(01)00333-5
更新日期：2001-10-01 00:00:00
abstract：:The aim of this study was to investigate the postnatal development of mu-(MOR) and delta-opioid receptor (DOR) immunoreactivity in rat dorsal root ganglia. Lumbar dorsal root ganglia (DRG) from postnatal day (P) 0, 3, 7 and 21 rat pups were immunostained for MOR and DOR. Proportions of MOR +ve and DOR +ve cells were c...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(00)00397-3
更新日期：2001-02-01 00:00:00
abstract：:The N-methyl-D-aspartic acid (NMDA) receptor antagonist D, L-2-amino-5-phosphonopentanoic acid (AP5) caused a stronger inhibition of wind-up in single wide dynamic range (WDR) neurons after carrageenan inflammation compared with control neurons without inflammation in the receptive field. This indicates that even a sh...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(99)00155-4
更新日期：1999-12-01 00:00:00
abstract：:Individual differences in interoceptive sensitivity are associated with differences in reported intensity of emotional experience, vulnerability to anxiety and mood disorder and capacity for emotional self-regulation. Enhanced sensitivity to autonomic state is often accompanied by increased autonomic reactivity. Here ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2012.04.030
更新日期：2012-08-01 00:00:00
abstract：:Chronic or episodic severe itch is recurrent in atopic dermatitis (AD). Nonhistaminergic itch pathways are suggested to dominate in AD itch, contributing to an "itch-scratch-itch cycle" that prolongs and worsens itch, pain, and skin lesions. We hypothesized that nonhistaminergic neuronal sensitization contributes to i...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000000980
更新日期：2017-09-01 00:00:00
