Atopic asthma is dominant in elderly onset asthmatics: possibility for an alteration of mast cell function by aging through Fc receptor expression.

abstract：BACKGROUND:Sensitivity to Chenopodiaceae is a frequent cause of allergic respiratory diseases in geographic areas where sensitization to Salsola kali and Chenopodium album has been reported. The objective of this study was to evaluate the pattern of sensitization to 3 Salsola species in patients residing on the Mediter...

journal_title：International archives of allergy and immunology

authors： Ferrer A,Larramendi CH,Huertas AJ,Pagán JA,Andreu C,García-Abujeta JL,López-Matas MA,Carnés J

更新日期：2010-01-01 00:00:00

abstract：:We isolated a major wheat flour allergen with a molecular weight of 15-kD. The 15-kD allergen was purified from an extract of wheat flour by ammonium sulfate precipitation followed by gel filtration. Using the immunoblot technique, IgE, specifically directed towards the single isolated allergen, was detectable in 50% ...

journal_title：International archives of allergy and immunology

authors： Fränken J,Stephan U,Meyer HE,König W

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Disturbed cytokine production is thought to govern inflammation in asthma, which, in its turn, may lead to uncontrolled disease. The aim of this study was to assess the relationship between cytokine production from blood leucocytes and the level of asthma control. METHODS:We compared the production of inter...

journal_title：International archives of allergy and immunology

authors： Manise M,Schleich F,Quaedvlieg V,Moermans C,Henket M,Sele J,Corhay JL,Louis R

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Interleukin (IL)-33, a new member of the IL-1 cytokine family, has been recognized as a key cytokine that enhances T helper 2-balanced immune regulation through its receptor ST2; however, the function and relationship of the IL-33 and ST2 pathways in bronchial asthma are still unclear. We investigated the ce...

journal_title：International archives of allergy and immunology

authors： Kurokawa M,Matsukura S,Kawaguchi M,Ieki K,Suzuki S,Odaka M,Watanabe S,Homma T,Sato M,Yamaguchi M,Takeuchi H,Adachi M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Patients with chronic urticaria (CU) in the UK could be referred to health care professionals (HCPs) with diverse specialties using different guidelines. The aims of the present study were to determine which CU guidelines HCPs in the UK use, which tests they use for the diagnosis of CU, and how they manage C...

journal_title：International archives of allergy and immunology

authors： Wu CH,Ardern-Jones MR,Eren E,Venter C

更新日期：2015-01-01 00:00:00

abstract：:Delayed drug allergy reactions (DDAR) are potentially fatal. Certain human leukocyte antigen (HLA) alleles have been associated with delayed allergy reactions following the administration of particular drugs. Examples are HLA-B*57:01 (abacavir), HLA-B*15:02/HLA-A*31:01 (carbamazepine), and HLA-B*58:01 (allopurinol). B...

journal_title：International archives of allergy and immunology

authors： Sousa-Pinto B,Correia C,Gomes L,Gil-Mata S,Araújo L,Correia O,Delgado L

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The so-called 'latex-fruit syndrome' is a well-documented phenomenon in cross-reactive allergies. By contrast, there is a lack of information about allergy to exotic fruits in patients with a predominant pollen sensitization. Since the ubiquitous protein profilin has been identified as an allergen in natural...

journal_title：International archives of allergy and immunology

authors： Reindl J,Rihs HP,Scheurer S,Wangorsch A,Haustein D,Vieths S

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:The allergenic potential of chicken egg white ovomucoid (OVM) is thought to depend on its stability to heat treatment and digestion. Pepsin-digested fragments have been speculated to continue to exert an allergenic potential. OVM was digested in simulated gastric fluid (SGF) to examine the reactivity of the ...

journal_title：International archives of allergy and immunology

authors： Takagi K,Teshima R,Okunuki H,Itoh S,Kawasaki N,Kawanishi T,Hayakawa T,Kohno Y,Urisu A,Sawada J

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Pre-clinical and clinical studies have evaluated the efficacy of probiotics in allergy. However, predictive in vitro systems for rational strain selection are still missing. METHODS:We developed a novel in vitro screening system for the characterization of probiotics with anti-allergic potential. In this mo...

journal_title：International archives of allergy and immunology

authors： Holvoet S,Zuercher AW,Julien-Javaux F,Perrot M,Mercenier A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:A growing body of evidence suggests that proinflammatory cytokines play a role in allergic inflammation by attracting and activating inflammatory cells. In this study, we have investigated the relationship between interleukin-8 (IL-8) in nasal lavage fluid and the local activation of eosinophils and neutroph...

journal_title：International archives of allergy and immunology

authors： Jacobi HH,Poulsen LK,Reimert CM,Skov PS,Ulfgren AK,Jones I,Elfman LB,Malling HJ,Mygind N

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Hypersensitivity to contrast media (CMs) may be common and serious. AIM:To evaluate the prevalence of CM hypersensitivity, risk factors associated with it and the role of skin testing in its diagnosis. METHODS:A structured questionnaire was administered to patients who underwent computed tomography during ...

journal_title：International archives of allergy and immunology

authors： Goksel O,Aydın O,Atasoy C,Akyar S,Demirel YS,Misirligil Z,Bavbek S

更新日期：2011-01-01 00:00:00

abstract：:Monoclonal antibody 2F5 recognizing the ELDKWA epitope on HIV-1 gp41 has a significant neutralization potency against 90% of the investigated viruses of African, Asian, American, and European strains, but the antibody responses to the epitope 2F5 in HIV-1-infected individuals were very low. We attempted to induce high...

journal_title：International archives of allergy and immunology

authors： Xiao Y,Dong X,Chen Y

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Sweating can worsen atopic dermatitis (AD). The purpose of this work was to study the associations between reactivity to autologous sweat and the clinical severity of AD as well as investigate the possible wheal-inducing factors of sweat. METHODS:Intracutaneous skin tests with autologous sweat were performe...

journal_title：International archives of allergy and immunology

authors： Ilves T,Virolainen A,Harvima IT

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Nasal polyps are a common health problem that can significantly impact the quality of life. OBJECTIVE:To analyze the impact of allergy and peripheral eosinophils (EOS) on the morbidity of chronic rhinosinusitis with nasal polyps (CRSwNP) in Northwest China. METHODS:A retrospective cohort of 323 patients wh...

journal_title：International archives of allergy and immunology

authors： Chen F,Wen L,Qiao L,Shi Z,Xue T,Chen X,Li X

更新日期：2019-01-01 00:00:00

abstract：:Reversible airway obstruction and airway inflammation following allergen exposure represent crucial pathophysiological features of allergic asthma. In order to investigate these events, bronchial-specific challenge is commonly employed although it may be complicated and may not be free of possible risks. Therefore, we...

journal_title：International archives of allergy and immunology

authors： Ciprandi G,Buscaglia S,Scordamaglia A,Canonica GW

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:15-Deoxy-Delta(12,14)-prostaglandin J2 (15d-PGJ2), a major prostanoid metabolized from prostaglandin D2 (PGD2), plays an important role in various biological processes including inflammatory responses. 15d-PGJ2 exerts its effects through two major receptors, chemoattractant receptor- homologous molecule expr...

journal_title：International archives of allergy and immunology

authors： Chiba T,Ueki S,Ito W,Kato H,Takeda M,Kayaba H,Furue M,Chihara J

更新日期：2009-01-01 00:00:00

abstract：:Human mononuclear leukocytes (MNL), probably OKT4-positive T cells, produced an eosinophil chemotactic factor (ECF) when they were cocultured with irradiated BALL-1, a B cell lymphoma line. Treatment of MNL, with anti-IL-2 antibody failed to suppress BALL-1-induced ECF production. Periodate-lysine-paraformaldehyde-fix...

journal_title：International archives of allergy and immunology

authors： Yoshida N,Ueno M,Saita N,Hirashima M

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:There is no information whether galectin-9 (a novel eosinophil chemoattractant) was associated with pathogenesis of eosinophilic disorders. METHODS:We assessed the expression of galectin-9 with imunostaining and in situ hybridization both in the lesion of angiolymphoid hyperplasia with eosinophilia, and per...

journal_title：International archives of allergy and immunology

authors： Saita N,Goto E,Yamamoto T,Cho I,Tsumori K,Kohrogi H,Maruo K,Ono T,Takeya M,Kashio Y,Nakamura K,Hirashima M

更新日期：2002-05-01 00:00:00

abstract：:Factors are discussed as potential diagnostic parameters of atopic disorders. The amounts of sCD23 in sera from newborn children (n = 4,329) were determined by radioimmunoassay with monoclonal antibodies specific for CD23. The sCD23 levels ranged between 0 and 81.5 ng/ml of CD23-specific mAb. Furthermore, the sera of ...

journal_title：International archives of allergy and immunology

authors： Bujanowski-Weber J,Knöller I,Wahn U,König W

更新日期：1992-01-01 00:00:00

abstract：:Epithelial cells line all cavities and surfaces throughout the body and play a substantial role in maintaining tissue homeostasis. Asthma and other atopic diseases are increasing worldwide and allergic disorders are hypothesized to be a consequence of a combination of dysregulation of the epithelial response towards e...

journal_title：International archives of allergy and immunology

authors： Papazian D,Würtzen PA,Hansen SW

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Mast cell tryptase has recently been reported to be involved in atherosclerotic plaque destabilization. However, the results of these reports are conflicting. METHODS:The aim of this study was to characterize the role of tryptase as a prognostic marker of patient cardiovascular complexity in acute coronary ...

journal_title：International archives of allergy and immunology

authors： Pastorello EA,Morici N,Farioli L,Di Biase M,Losappio LM,Nichelatti M,Lupica L,Schroeder JW,Stafylaraki C,Klugmann S

更新日期：2014-01-01 00:00:00

abstract：:Volumetric air sampling was performed at Corpus Christi, Tex., September 1987 to August 1989. Grass aeropollen during all of 1988 accounted for 15.3% of total pollen captured during two major peaks, one in May and another during September and October. The remaining grass pollen, about one-quarter of the total, was fou...

journal_title：International archives of allergy and immunology

authors： Lewis WH,Dixit AB,Wedner HJ

更新日期：1992-01-01 00:00:00

abstract：:Increased serum IgE and enhanced susceptibility to viral infections, decreased levels of interferons, lymphocytic skin infiltrates and IgE-bearing epidermal Langerhans cells are striking features in patients with atopic eczema (AE). Since the hyper-IgE syndrome is known to improve under alpha-interferon (alpha-IFN) th...

journal_title：International archives of allergy and immunology

authors： Gruschwitz MS,Peters KP,Heese A,Stosiek N,Koch HU,Hornstein OP

更新日期：1993-01-01 00:00:00

abstract：:The aim of this study was to assess the relevance of immunoinflammatory markers on the response to short acting beta(2)-agonist in acute asthma exacerbation. Thus, we measured serum eosinophil cationic protein (ECP) levels and sIL-2R at acute exacerbation in 52 adult patients with atopic asthma, and assessed forced ex...

journal_title：International archives of allergy and immunology

authors： Di Lorenzo G,Pacor ML,Morici G,Drago A,Esposito-Pellitteri M,Candore G,Lo Bianco C,Caruso C

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Galectin-9 was recently identified as a ligand for Tim-3, which negatively regulates Th1 cells. Here, we investigated whether administration of anti-galectin-9 antibodies (Abs) affects the development of murine experimental allergic conjunctivitis (EC), a Th2-mediated disease. METHODS:EC was induced in BALB...

journal_title：International archives of allergy and immunology

authors： Fukushima A,Sumi T,Fukuda K,Kumagai N,Nishida T,Okumura K,Akiba H,Yagita H,Ueno H

更新日期：2008-01-01 00:00:00

abstract：:IL-3-dependent, murine mast cell lines derived from embryonic yolk sac precursors display a tumoricidal activity that is blocked by antibodies against tumor necrosis factor-alpha, indicating that this cytokine is the major mediator involved in the cytotoxic activity of the cultured mast cell lines. Further, cholera to...

journal_title：International archives of allergy and immunology

authors： Manning JK,Malkovsky M,Meager A

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Data regarding the prevalence of chronic spontaneous urticaria (CSU) in childhood-onset systemic lupus erythematosus (cSLE) patients and possible associated factors are limited to a few case reports. The objectives of this study were to assess CSU in a large cSLE population, in order to evaluate the demograp...

journal_title：International archives of allergy and immunology

authors： Ferriani MP,Silva MF,Pereira RM,Terreri MT,Saad Magalhães C,Bonfá E,Pastorino AC,Carolina Dos Santos M,Appenzeller S,Ferriani VP,Len CA,Sallum AM,Libório J,Monteiro de Castro TC,Silva CA

更新日期：2015-01-01 00:00:00

abstract：:In all mammalian species investigated so far, mast cells and basophils are the only cells that synthesize histamine and express plasma membrane receptors that bind IgE with high affinity (Fc epsilonRI). Human basophils and mast cells derive from distinct precursors that originate in the bone marrow and fetal liver and...

journal_title：International archives of allergy and immunology

authors： Marone G,Casolaro V,Patella V,Florio G,Triggiani M

更新日期：1997-11-01 00:00:00

abstract：:Ever since the realization that T lymphocytes are key players in the defense against pathogens and tumors, a major aim of immunologists has been to understand the relationship between the functional and migratory properties of antigen-specific T cells. The current paradigm proposes that T cells follow organ-specific t...

journal_title：International archives of allergy and immunology

authors： Iparraguirre A,Weninger W

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:The role of food allergens in the induction of allergic reactions in the airways is not completely understood. The aim of the present study was to evaluate fluorocytometric assays of the peripheral blood during food challenge tests in children with asthma and food allergy. PATIENTS AND METHODS:22 children w...

journal_title：International archives of allergy and immunology

authors： Krogulska A,Wasowska-Królikowska K,Polakowska E,Chrul S

更新日期：2009-01-01 00:00:00