Cortical Thickness in Alcohol Dependent Patients With Apathy.

abstract：Background:Recent meta-analyses reported placebo response rate in antidepressant trials to be stable since the 1970s. These meta-analyses however were limited in considering only linear time trends, assessed trial-level covariates based on single-model hypothesis testing only, and did not adjust for small-study effects...

journal_title：Frontiers in psychiatry

authors： Holper L

更新日期：2020-07-28 00:00:00

abstract：:Background: Recent models of eating disorders (EDs) have proposed social and emotional difficulties as key factors in the development and maintenance of the illness. While a number of studies have demonstrated difficulties in theory of mind and emotion recognition, little is known about empathic abilities in those wit...

journal_title：Frontiers in psychiatry

authors： Kerr-Gaffney J,Harrison A,Tchanturia K

更新日期：2019-03-04 00:00:00

abstract：Background:Past studies using the Bonn Scale for the Assessment of Basic Symptoms (hereafter, Bonn Scale) have shown that self-reported perceptual/cognitive disturbances reveal which persons have or will soon develop schizophrenia. Here, we focused specifically on the clinical value of self-reported visual perceptual a...

journal_title：Frontiers in psychiatry

authors： Keane BP,Cruz LN,Paterno D,Silverstein SM

更新日期：2018-03-12 00:00:00

abstract：:As the population ages and the number of people living with dementia or mild cognitive impairment (MCI) continues to increase, it is critical to identify creative and innovative ways to support and improve their quality of life. Motion-based technology has shown significant potential for people living with dementia or...

journal_title：Frontiers in psychiatry

authors： Astell AJ,Czarnuch S,Dove E

更新日期：2018-05-11 00:00:00

abstract：Background:Schizophrenia patients exhibit cognitive deficits across multiple domains, including verbal memory, working memory, and executive function, which substantially contribute to psychosocial disability. Gamma oscillations are associated with a wide range of cognitive operations, and are important for cortico-cor...

journal_title：Frontiers in psychiatry

authors： Tanaka-Koshiyama K,Koshiyama D,Miyakoshi M,Joshi YB,Molina JL,Sprock J,Braff DL,Light GA

更新日期：2020-08-31 00:00:00

abstract：:Motivated behaviors are often initiated in response to perturbations of homeostasis. Indeed, animals and humans have fundamental drives to procure (appetitive behaviors) and eventually ingest (consummatory behaviors) substances based on deficits in body fluid (e.g., thirst) and energy balance (e.g., hunger). Consumpti...

journal_title：Frontiers in psychiatry

authors： Hsu TM,McCutcheon JE,Roitman MF

更新日期：2018-09-03 00:00:00

abstract：:Previous work has demonstrated that goal-directed control of alcohol-seeking and other drug-related behaviors is reduced following extended self-administration and drug exposure. Here, we examined how the magnitude of stimulus influences on responding changes across similar training and drug exposure. Rats self-admini...

journal_title：Frontiers in psychiatry

authors： Corbit LH,Janak PH

更新日期：2016-10-10 00:00:00

abstract：:The view that anatomically distinct memory systems differentially contribute to the development of drug addiction and relapse has received extensive support. The present brief review revisits this hypothesis as it was originally proposed 20 years ago (1) and highlights several recent developments. Extensive research e...

journal_title：Frontiers in psychiatry

authors： Goodman J,Packard MG

更新日期：2016-02-25 00:00:00

abstract：:Increasing evidence suggests that binge eating-related disorders could be related to addiction-like eating patterns due to the addictive potential of hyperpalatable foods. Subsequently, important implications have been derived for treatment of those disorders and even political actions. However, studies on the prevale...

journal_title：Frontiers in psychiatry

authors： Meule A

更新日期：2011-11-03 00:00:00

abstract：:Background: Catatonic phenomena such as stupor, mutism, stereotypy, echolalia, echopraxia, affective flattening, psychomotor deficits, and social withdrawal are characteristic symptoms of both schizophrenia and autism spectrum disorders (ASD), suggesting overlapping pathophysiological similarities such as altered glut...

journal_title：Frontiers in psychiatry

authors： Hefter D,Topor CE,Gass P,Hirjak D

更新日期：2019-04-12 00:00:00

abstract：:Fragile X syndrome (FXS) is caused by the full mutation (>200 CGG repeats) in the Fragile X Mental Retardation 1 (FMR1) gene. It is the most common inherited cause of intellectual disability (ID) and autism. This review focuses on neuropsychiatric disorders frequently experienced by premutation carriers with 55 to 200...

journal_title：Frontiers in psychiatry

authors： Hagerman RJ,Protic D,Rajaratnam A,Salcedo-Arellano MJ,Aydin EY,Schneider A

更新日期：2018-11-13 00:00:00

abstract：:HIV-related stigma has been documented as one of the greatest obstacles to reducing HIV spread, engagement in HIV treatment, and poor mental health functioning among people living with HIV (PLWH). Although disclosure is important for people to receive social support, the fear of stigma and discrimination prevents PLWH...

journal_title：Frontiers in psychiatry

authors： Nabunya P,Byansi W,Sensoy Bahar O,McKay M,Ssewamala FM,Damulira C

更新日期：2020-07-31 00:00:00

abstract：:While psychological treatments have been shown to be effective in treating psychiatric disorders, the mechanism of their therapeutic effect is less well understood. An improved mechanistic understanding of psychiatric disorders and their treatments would enable refinement of existing interventions, and more targeted i...

journal_title：Frontiers in psychiatry

authors： Griffin B,Saunders KEA

更新日期：2020-01-17 00:00:00

abstract：BACKGROUND:The treatment of cocaine-dependent individuals (CDI) is substantially challenged by high drop-out rates, raising questions regarding contributing factors. Recently, a number of studies have highlighted the potential of greater focus on the clinical significance of neurocognitive impairments in treatment-seek...

journal_title：Frontiers in psychiatry

authors： Stevens L,Betanzos-Espinosa P,Crunelle CL,Vergara-Moragues E,Roeyers H,Lozano O,Dom G,Gonzalez-Saiz F,Vanderplasschen W,Verdejo-García A,Pérez-García M

更新日期：2013-11-15 00:00:00

abstract：:Converging lines of evidence indicates that smoking and internet gaming disorder (IGD) affect spontaneous brain activity, respectively. However, little is known about whether these two factors work together on the human brain. In this study, we investigated the interaction between smoking and IGD on local spontaneous ...

journal_title：Frontiers in psychiatry

authors： Qiu X,Han X,Wang Y,Ding W,Sun Y,Zhou Y,Lei H,Lin F

更新日期：2020-12-03 00:00:00

abstract：:We use auditory verbal hallucinations (AVH) to illustrate the challenges in defining and assessing target engagement in the context of transcranial direct current stimulation (tDCS) for psychiatric disorders. We defined the target network as the cluster of regions of interest (ROIs) that are consistently implicated in...

journal_title：Frontiers in psychiatry

authors： Lee WH,Kennedy NI,Bikson M,Frangou S

更新日期：2018-02-22 00:00:00

abstract：:Background: Inpatient mental health wards are reported by many consumers to be custodial, unsafe, and lacking in therapeutic relationships. These consumer experiences are concerning, given international policy directives requiring recovery-oriented practice. Safewards is both a model and a suite of interventions desig...

journal_title：Frontiers in psychiatry

authors： Fletcher J,Buchanan-Hagen S,Brophy L,Kinner SA,Hamilton B

更新日期：2019-07-09 00:00:00

abstract：:Despite many studies documenting the prevalence of various co-occurring psychiatric symptoms in children and adults with ASD, less is known about how these symptoms relate to subtypes defined by particular phenotypic features within the ASD population. We examined the severity and prevalence of comorbid symptoms of ps...

journal_title：Frontiers in psychiatry

authors： Plesa Skwerer D,Joseph RM,Eggleston B,Meyer SR,Tager-Flusberg H

更新日期：2019-02-18 00:00:00

abstract：:Introduction: Previous studies have indicated that changes in the concentration of glutamate and related metabolites may mediate the progression of addiction in patients with methamphetamine (MA) use disorders. In the present study, we utilized magnetic resonance spectroscopy (MRS) to investigate absolute glutamate co...

journal_title：Frontiers in psychiatry

authors： Yang W,Yang R,Luo J,He L,Liu J,Zhang J

更新日期：2018-08-31 00:00:00

abstract：:Community integration is recognized as a meaningful goal that is highly relevant to the long-term success of supportive housing programs. Research to date highlights concerns that some individuals in permanent supportive housing remain socially isolated and have limited success in other domains of community integratio...

journal_title：Frontiers in psychiatry

authors： Chinchilla M,Gabrielian S,Hellemann G,Glasmeier A,Green M

更新日期：2019-06-26 00:00:00

abstract：:Socioeconomic status is a strong predictor of normative development and well-being in young people. It is well-known that growing up in a socioeconomically disadvantaged context may lead to negative outcomes, both in childhood and in adulthood. Early intervention and prevention programmes are crucial for building resi...

journal_title：Frontiers in psychiatry

authors： Kara B,Morris R,Brown A,Wigglesworth P,Kania J,Hart A,Mezes B,Cameron J,Eryigit-Madzwamuse S

更新日期：2021-01-14 00:00:00

abstract：:In this short review, we want to summarize the current findings on the role of vitamin-D in multiple sclerosis (MS), schizophrenia, and autism. Many studies have highlighted hypovitaminosis-D as a potential environmental risk factor for a variety of conditions such as MS, asthma, cardiovascular disease, and, more rece...

journal_title：Frontiers in psychiatry

authors： Kočovská E,Gaughran F,Krivoy A,Meier UC

更新日期：2017-03-27 00:00:00

abstract：:Inflammation and immune dysregulation could contribute to the pathogenesis of schizophrenia. Osteopontin (OPN) is a cytokine-like glycoprotein involved in inflammation and in modulating immune responses, and it can also directly modify the cytokine expression and survival of microglia. Furthermore, elevated gene expre...

journal_title：Frontiers in psychiatry

authors： Kovács MÁ,Tényi T,Kugyelka R,Prenek L,Hau L,Magyar ÉE,Herold R,Balogh P,Simon D

更新日期：2020-01-23 00:00:00

abstract：:Glutamate is involved in excitatory neurotransmission and metabolic processes related to brain function. Previous studies using proton functional magnetic resonance spectroscopy (1H fMRS) have demonstrated elevated cortical glutamate levels by 2-4% during visual and motor stimulation, relative to periods of no stimula...

journal_title：Frontiers in psychiatry

authors： Woodcock EA,Anand C,Khatib D,Diwadkar VA,Stanley JA

更新日期：2018-03-06 00:00:00

abstract：:The high rate of comorbidity between insomnia and anxiety disorders have been confirmed by previous studies. However, the underlying neurobiological correlates of the relationship between insomnia and anxiety disorders are largely unknown. The aim of the present study was to investigate the effect of insomnia on corti...

journal_title：Frontiers in psychiatry

authors： Huang Z,Zhan S,Chen C,Li N,Ding Y,Hou Y,Wang L,Wang Y

更新日期：2019-01-10 00:00:00

abstract：:Cogmed Working Memory Training (CWMT), an online cognitive training program developed for children, is an increasingly popular non-pharmacological intervention for ADHD amongst all ages, despite limited supporting evidence. The initial objective of the present work was to examine the short- and long-term impacts of CW...

journal_title：Frontiers in psychiatry

authors： Marcelle ET,Ho EJ,Kaplan MS,Adler LA,Castellanos FX,Milham MP

更新日期：2018-08-28 00:00:00

abstract：:Recent work on the mechanisms underlying auditory verbal hallucination (AVH) has been heavily informed by self-monitoring accounts that postulate defects in an internal monitoring mechanism as the basis of AVH. A more neglected alternative is an account focusing on defects in auditory processing, namely a spontaneous ...

journal_title：Frontiers in psychiatry

authors： Cho R,Wu W

更新日期：2013-11-27 00:00:00

abstract：:Biomarkers are of interest as potential diagnostic and predictive instruments in personalized medicine. We present the first urinary metabolomics biomarker study of childhood aggression. We aim to examine the association of urinary metabolites and neurotransmitter ratios involved in key metabolic and neurotransmitter ...

journal_title：Frontiers in psychiatry

authors： Hagenbeek FA,Roetman PJ,Pool R,Kluft C,Harms AC,van Dongen J,Colins OF,Talens S,van Beijsterveldt CEM,Vandenbosch MMLJZ,de Zeeuw EL,Déjean S,Fanos V,Ehli EA,Davies GE,Hottenga JJ,Hankemeier T,Bartels M,Vermeiren RRJM

更新日期：2020-03-31 00:00:00

abstract：:Defense mechanisms are psychological factors that influence emotional distress and quality of life. There are a number of measures assessing the construct of defense mechanisms, but only few available instruments reflect the gold-standard theoretical hierarchical organization of defenses. We report on the development ...

journal_title：Frontiers in psychiatry

authors： Di Giuseppe M,Perry JC,Lucchesi M,Michelini M,Vitiello S,Piantanida A,Fabiani M,Maffei S,Conversano C

更新日期：2020-08-26 00:00:00

abstract：:Objective: During the outbreak of the COVID-19 epidemic in China, breast cancer (BC) patients and healthcare workers faced several challenges, resulting in great psychological stress. We measured the psychological status of BC patients and female nurses and compared the severity within the two groups at the peak time-...

journal_title：Frontiers in psychiatry

authors： Cui Q,Cai Z,Li J,Liu Z,Sun S,Chen C,Wang G

更新日期：2020-12-15 00:00:00