Raising Placebo Efficacy in Antidepressant Trials Across Decades Explained by Small-Study Effects: A Meta-Reanalysis.

abstract：:Over the past years, there has been a growing interest in the association between lifestyle psychosocial interventions, severe mental illness, and suicide risk. Patients with severe mental disorders have higher mortality rates, poor health states, and higher suicide risk compared to the general population. Lifestyle b...

journal_title：Frontiers in psychiatry

authors： Berardelli I,Corigliano V,Hawkins M,Comparelli A,Erbuto D,Pompili M

更新日期：2018-11-06 00:00:00

abstract：:In the brain of female mammals, including humans, a number of physiological and behavioral changes occur as a result of sex hormone exposure. Estradiol and progesterone regulate several brain functions, including learning and memory. Sex hormones contribute to shape the central nervous system by modulating the formati...

journal_title：Frontiers in psychiatry

authors： Hansberg-Pastor V,González-Arenas A,Piña-Medina AG,Camacho-Arroyo I

更新日期：2015-11-20 00:00:00

abstract：:Several studies investigated the role of resilience as a mediating factor for psychopathological phenotypes. The aim of the current study is to explore the putative role of resilience as a mediator between different vulnerability factors and depressive symptoms. One hundred and fifty patients with a major depressive d...

journal_title：Frontiers in psychiatry

authors： Collazzoni A,Stratta P,Pacitti F,Rossi A,Santarelli V,Bustini M,Talevi D,Socci V,Rossi R

更新日期：2020-02-28 00:00:00

abstract：:Biomarkers are of interest as potential diagnostic and predictive instruments in personalized medicine. We present the first urinary metabolomics biomarker study of childhood aggression. We aim to examine the association of urinary metabolites and neurotransmitter ratios involved in key metabolic and neurotransmitter ...

journal_title：Frontiers in psychiatry

authors： Hagenbeek FA,Roetman PJ,Pool R,Kluft C,Harms AC,van Dongen J,Colins OF,Talens S,van Beijsterveldt CEM,Vandenbosch MMLJZ,de Zeeuw EL,Déjean S,Fanos V,Ehli EA,Davies GE,Hottenga JJ,Hankemeier T,Bartels M,Vermeiren RRJM

更新日期：2020-03-31 00:00:00

abstract：:Disrupted white matter (WM) integrity in the anterior thalamic radiation (ATR) has been identified in individuals with bipolar disorder (BD). We explored whether structural WM aberration in the ATR could be visually evaluated by diffusion tensor tractography (DTT). The study comprised 114 participants, including 57 pa...

journal_title：Frontiers in psychiatry

authors： Niida R,Yamagata B,Niida A,Uechi A,Matsuda H,Mimura M

更新日期：2018-10-24 00:00:00

abstract：:Objective: We previously found that chronic ketamine usages were associated with various psychotic and cognitive symptoms mimicking schizophrenia. The blockade of the NMDA receptor and subsequent nitric oxide synthase 1 (NOS1) dysfunction were found to be closely correlated with schizophrenia including NOS1 gene polym...

journal_title：Frontiers in psychiatry

authors： Chen J,Zhang M,Zhou C,Ding Y,Fan N,He H

更新日期：2020-12-23 00:00:00

abstract：Background:Depression is pervasive in the military context and is likely to elicit lasting negative effects on health. Based on interpersonal models, social-interpersonal stressors are significantly associated with the development and maintenance of depression. However, little is known about the mechanisms by which the...

journal_title：Frontiers in psychiatry

authors： Wang J,Cheng X,Xu K,Xu H,Wang H,Feng Z

更新日期：2020-06-18 00:00:00

abstract：:This study explored how different forms of reward-based decision-making are associated with pathological gambling (PG) among abstinent individuals with prior dependence on different classes of drugs. Participants had lifetime histories of either "pure" heroin dependence (n = 64), "pure" amphetamine dependence (n = 51)...

journal_title：Frontiers in psychiatry

authors： Wilson MJ,Vassileva J

更新日期：2018-06-05 00:00:00

abstract：BACKGROUND:Electroconvulsive therapy (ECT) is effective in the treatment of major depressive disorder and schizophrenia in patients who are drug-naïve or less-receptive to antipsychotic drugs. Several studies have discussed the correlation between patient characteristics, input-current volume, and seizure duration. Acc...

journal_title：Frontiers in psychiatry

authors： Wang CC,Lin CH,Chiu YC,Tseng CC

更新日期：2013-12-23 00:00:00

abstract：:Background: COVID-19 affects not only patients' physical health but also their mental health. For the general public, although their physical health may not be directly affected, their mental health may be affected by stress, anxiety, and social panic caused by COVID-19. Controlling the pandemic should focus on not on...

journal_title：Frontiers in psychiatry

authors： Wang S,Feng K,Zhang Y,Liu J,Wang W,Li Y

更新日期：2020-11-12 00:00:00

abstract：:Excessive glutamate release has been linked to stress and many neurodegenerative diseases. Evidence indicates abnormalities of glutamatergic neurotransmission or glutamatergic dysfunction as playing an important role in the development of many major psychiatric disorders (e.g., schizophrenia, bipolar disorder, and maj...

journal_title：Frontiers in psychiatry

authors： Li CT,Yang KC,Lin WC

更新日期：2019-01-24 00:00:00

abstract：Objectives:Deviations from typical word use have been previously reported in clinical depression, but language patterns of mild depression (MD), as distinct from normal sadness (NS) and euthymic state, are unknown. In this study, we aimed to apply the linguistic approach as an additional diagnostic key for understandin...

journal_title：Frontiers in psychiatry

authors： Smirnova D,Cumming P,Sloeva E,Kuvshinova N,Romanov D,Nosachev G

更新日期：2018-04-10 00:00:00

abstract：:Cognitive performance at illness onset may predict outcomes in first-episode psychosis (FEP), and the change in cognition may associate with clinical changes. Cognitive testing was administered to 54 FEP participants 2 months after entering treatment and to 39 participants after 1 year. We investigated whether baselin...

journal_title：Frontiers in psychiatry

authors： Lindgren M,Holm M,Kieseppä T,Suvisaari J

更新日期：2020-12-04 00:00:00

abstract：:The aim of this study is to explore the changes and clinical significance of serum C3, C4, hypersensitive C-reactive protein (hsCRP) and uric acid (UA) in patients of bipolar disorder (BD). In this case-control study, we recruited 141 BD patients from The Second Xiangya Hospital, Central South University, and 151 age ...

journal_title：Frontiers in psychiatry

authors： Yang X,Tao H,Xiao L,Li C,Tang Y,Liu Y

更新日期：2018-08-21 00:00:00

abstract：Background:Neuropsychological studies have revealed that patients with schizophrenia (SZ) have facial recognition difficulties and a reduced visual evoked N170 response to human faces. However, detailed neurophysiological evidence of this face processing deficit in SZ with a higher spatial resolution has yet to be acqu...

journal_title：Frontiers in psychiatry

authors： Ohara N,Hirano Y,Oribe N,Tamura S,Nakamura I,Hirano S,Tsuchimoto R,Ueno T,Togao O,Hiwatashi A,Nakao T,Onitsuka T

更新日期：2020-09-03 00:00:00

abstract：:Cogmed Working Memory Training (CWMT), an online cognitive training program developed for children, is an increasingly popular non-pharmacological intervention for ADHD amongst all ages, despite limited supporting evidence. The initial objective of the present work was to examine the short- and long-term impacts of CW...

journal_title：Frontiers in psychiatry

authors： Marcelle ET,Ho EJ,Kaplan MS,Adler LA,Castellanos FX,Milham MP

更新日期：2018-08-28 00:00:00

abstract：Background:Previous studies have revealed the efficacy of metacognitive training for schizophrenia. However, the underlying mechanisms of metacognitive training on brain function alterations, including the default-mode network (DMN), remain unknown. The present study explored treatment effects of metacognitive training...

journal_title：Frontiers in psychiatry

authors： Shan X,Liao R,Ou Y,Ding Y,Liu F,Chen J,Zhao J,Guo W,He Y

更新日期：2020-03-27 00:00:00

abstract：Background:Opiate addiction is a major health problem in many countries. A crucial component of the medical treatment is the management of highly aversive opiate withdrawal signs, which may otherwise lead to resumption of drug taking. In a medication-assisted treatment (MAT), methadone and buprenorphine have been imple...

journal_title：Frontiers in psychiatry

authors： Hassan R,Pike See C,Sreenivasan S,Mansor SM,Müller CP,Hassan Z

更新日期：2020-05-07 00:00:00

abstract：:Baclofen, particularly high-dose baclofen, has recently emerged as a treatment of major interest for alcohol-dependence. However, baclofen has many potentially dangerous side effects, and the maximal dose of baclofen that may be used is a matter of discussion. Here, the author analyses the medical charts of the last 1...

journal_title：Frontiers in psychiatry

authors： de Beaurepaire R

更新日期：2014-10-10 00:00:00

abstract：:The dark triad (DT) traits-psychopathy, narcissism and Machiavellianism-have collectively been linked to reduced empathy and increased aggression; however, their association with distinct empathic subtypes remains unclear; and unique links to indirect relational aggression (IRA) have not been delineated. Moreover, whe...

journal_title：Frontiers in psychiatry

authors： Heym N,Firth J,Kibowski F,Sumich A,Egan V,Bloxsom CAJ

更新日期：2019-03-12 00:00:00

abstract：:This study compares the impact of repeated injections of baclofen (an agonist of GABAB receptors) or diazepam (a benzodiazepine having an agonist action on GABAA receptors) given during the alcohol-withdrawal period on the stress-induced restoration of alcohol-seeking behavior and hypothalamic-pituitary-adrenal (HPA) ...

journal_title：Frontiers in psychiatry

authors： Rabat Y,Henkous N,Corio M,Nogues X,Beracochea D

更新日期：2019-04-16 00:00:00

abstract：INTRODUCTION:Ruminative (abstract verbal) processing during recall of aversive autobiographical memories may serve to dampen their short-term affective impact. Experimental studies indeed demonstrate that verbal processing of non-autobiographical material and positive autobiographical memories evokes weaker affective r...

journal_title：Frontiers in psychiatry

authors： Slofstra C,Eisma MC,Holmes EA,Bockting CLH,Nauta MH

更新日期：2017-05-30 00:00:00

abstract：:Objective: During the outbreak of the COVID-19 epidemic in China, breast cancer (BC) patients and healthcare workers faced several challenges, resulting in great psychological stress. We measured the psychological status of BC patients and female nurses and compared the severity within the two groups at the peak time-...

journal_title：Frontiers in psychiatry

authors： Cui Q,Cai Z,Li J,Liu Z,Sun S,Chen C,Wang G

更新日期：2020-12-15 00:00:00

abstract：:We use auditory verbal hallucinations (AVH) to illustrate the challenges in defining and assessing target engagement in the context of transcranial direct current stimulation (tDCS) for psychiatric disorders. We defined the target network as the cluster of regions of interest (ROIs) that are consistently implicated in...

journal_title：Frontiers in psychiatry

authors： Lee WH,Kennedy NI,Bikson M,Frangou S

更新日期：2018-02-22 00:00:00

abstract：:Several studies support currently the hypothesis that autism etiology is based on a polygenic and epistatic model. However, despite advances in epidemiological, molecular and clinical genetics, the genetic risk factors remain difficult to identify, with the exception of a few chromosomal disorders and several single g...

journal_title：Frontiers in psychiatry

authors： Tordjman S,Somogyi E,Coulon N,Kermarrec S,Cohen D,Bronsard G,Bonnot O,Weismann-Arcache C,Botbol M,Lauth B,Ginchat V,Roubertoux P,Barburoth M,Kovess V,Geoffray MM,Xavier J

更新日期：2014-08-04 00:00:00

abstract：:Psychological stress is recognized as a major modifiable risk factor for adult non-communicable disease (NCD) that includes depression, type 2 diabetes mellitus, and cardiovascular disease. Dysregulation of hypothalamic-pituitary-adrenal (HPA) axis activity resulting in either exaggerated or blunted cortisol responses...

journal_title：Frontiers in psychiatry

authors： Krishnaveni GV,Srinivasan K

更新日期：2019-10-29 00:00:00

abstract：:Individuals with schizophrenia, particularly those with passivity symptoms, may not feel in control of their actions, believing them to be controlled by external agents. Cognitive operations that contribute to these symptoms may include abnormal processing in agency as well as body representations that deal with body ...

journal_title：Frontiers in psychiatry

authors： Graham KT,Martin-Iverson MT,Holmes NP,Jablensky A,Waters F

更新日期：2014-09-10 00:00:00

abstract：:The One-to-One program aims to reduce criminal recidivism among prisoners shortly awaiting release, and among probationers. Of 1,484 program participants in Sweden, 776 contained adequate data for analysis. Pre- and post-program scores were available for the Alternative Thinking Test, Levenson's Locus of Control Scale...

journal_title：Frontiers in psychiatry

authors： Berman AH,Gajecki M,Morien P,Priestley P

更新日期：2019-11-29 00:00:00

abstract：:The prevalence of alcohol abuse among patients treated in accident and emergency departments (A&E) is considered as substantial. This paper is a narrative review of studies investigating the effectiveness of brief interventions (BI) for hazardous and harmful alcohol consumption in A&E. A&E departments in hospitals (an...

journal_title：Frontiers in psychiatry

authors： Wojnar M,Jakubczyk A

更新日期：2014-11-03 00:00:00

abstract：:Background: Australia is a high-income country with increasing income inequality. It is unclear whether Australia's well-developed mental healthcare system is making a difference to population mental health and the Federal Government has targeted outcomes accountability in service funding strategies. In high-income co...

journal_title：Frontiers in psychiatry

authors： Isaacs AN,Enticott J,Meadows G,Inder B

更新日期：2018-10-26 00:00:00