Prevalence and Correlates of Psychiatric Symptoms in Minimally Verbal Children and Adolescents With ASD.

Abstract:

:Despite many studies documenting the prevalence of various co-occurring psychiatric symptoms in children and adults with ASD, less is known about how these symptoms relate to subtypes defined by particular phenotypic features within the ASD population. We examined the severity and prevalence of comorbid symptoms of psychopathology, emotion dysregulation, and maladaptive behaviors, as well as adaptive functioning, in a group of 65 minimally verbal children (n = 33) and adolescents (n = 32) with ASD. On the Child and Adolescent Symptom Inventory (CASI-5), for all the symptom classifications except oppositional defiant disorder and conduct disorder, more participants in our sample showed elevated or clinically concerning severity scores relative to the general population. On the Emotion Dysregulation Inventory (EDI), the mean scores for Reactivity and Dysphoria factors in our sample were lower than in the autism calibration sample, which included a large number of inpatient youth with ASD. Overall, few differences were found between the children and adolescents within this severely impaired group of ASD individuals based on clinical cutoff scores on the CASI-5 and EDI factor scores. Psychiatric comorbidities and emotion dysregulation measures were not correlated with autism symptom severity or with measures of adaptive functioning, and were largely unrelated to IQ in our sample. The number of clinically significant psychiatric symptoms on the CASI-5 emerged as the main predictor of maladaptive behaviors. Findings suggest a wide range of co-occurring psychopathology and high degree of maladaptive behavior among minimally verbal children and adolescents with ASD, which are not directly attributable to autism symptom severity, intellectual disability or limitations in adaptive functioning.

journal_name

Front Psychiatry

journal_title

Frontiers in psychiatry

authors

Plesa Skwerer D,Joseph RM,Eggleston B,Meyer SR,Tager-Flusberg H

doi

10.3389/fpsyt.2019.00043

subject

Has Abstract

pub_date

2019-02-18 00:00:00

pages

43

issn

1664-0640

journal_volume

10

pub_type

杂志文章
  • Rejection Sensitivity Mediates the Relationship Between Social-Interpersonal Stressors and Depressive Symptoms in Military Context.

    abstract:Background:Depression is pervasive in the military context and is likely to elicit lasting negative effects on health. Based on interpersonal models, social-interpersonal stressors are significantly associated with the development and maintenance of depression. However, little is known about the mechanisms by which the...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00447

    authors: Wang J,Cheng X,Xu K,Xu H,Wang H,Feng Z

    更新日期:2020-06-18 00:00:00

  • Using structural neuroimaging to make quantitative predictions of symptom progression in individuals at ultra-high risk for psychosis.

    abstract::Neuroimaging holds the promise that it may one day aid the clinical assessment of individual psychiatric patients. However, the vast majority of studies published so far have been based on average differences between groups, which do not permit accurate inferences at the level of the individual. We examined the potent...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2013.00187

    authors: Tognin S,Pettersson-Yeo W,Valli I,Hutton C,Woolley J,Allen P,McGuire P,Mechelli A

    更新日期:2014-01-29 00:00:00

  • Placing Cognitive Rigidity in Interpersonal Context in Psychosis: Relationship With Low Cognitive Reserve and High Self-Certainty.

    abstract::Introduction: People with psychosis show impairments in cognitive flexibility, a phenomenon that is still poorly understood. In this study, we tested if there were differences in cognitive and metacognitive processes related to rigidity in patients with psychosis. We compared individuals with dichotomous interpersonal...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.594840

    authors: García-Mieres H,Usall J,Feixas G,Ochoa S

    更新日期:2020-11-26 00:00:00

  • Prognostic Utility of Multivariate Morphometry in Schizophrenia.

    abstract::Background: Voxel-based morphometry studies have repeatedly highlighted the presence of distributed gray matter changes in schizophrenia, but to date, it is not clear if clinically useful prognostic information can be gleaned from structural imaging. The suspected association between gray matter volume (GMV) and durat...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2019.00245

    authors: Li M,Li X,Das TK,Deng W,Li Y,Zhao L,Ma X,Wang Y,Yu H,Meng Y,Wang Q,Palaniyappan L,Li T

    更新日期:2019-04-15 00:00:00

  • Modulation of Social Cognition via Hallucinogens and "Entactogens".

    abstract::Social cognition is a fundamental ability in human everyday lives. Deficits in social functioning also represent a core aspect of many psychiatric disorders. Yet, despite its significance, deficits in social cognition skills are insufficiently targeted by current treatments. Hallucinogens and entactogens have been sho...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2019.00881

    authors: Preller KH,Vollenweider FX

    更新日期:2019-12-03 00:00:00

  • Social Attention in Autism: Neural Sensitivity to Speech Over Background Noise Predicts Encoding of Social Information.

    abstract::Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by lack of attention to social cues in the environment, including speech. Hypersensitivity to sensory stimuli, such as loud noises, is also extremely common in youth with ASD. While a link between sensory hypersensitivity and impaired social...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00343

    authors: Hernandez LM,Green SA,Lawrence KE,Inada M,Liu J,Bookheimer SY,Dapretto M

    更新日期:2020-04-24 00:00:00

  • Manual Dexterity in Schizophrenia-A Neglected Clinical Marker?

    abstract::Impaired manual dexterity is commonly observed in schizophrenia. However, a quantitative description of key sensorimotor components contributing to impaired dexterity is lacking. Whether the key components of dexterity are differentially affected and how they relate to clinical characteristics also remains unclear. We...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2017.00120

    authors: Térémetz M,Carment L,Brénugat-Herne L,Croca M,Bleton JP,Krebs MO,Maier MA,Amado I,Lindberg PG

    更新日期:2017-07-10 00:00:00

  • Effects of COVID-19 Epidemic Lockdown on Postpartum Depressive Symptoms in a Sample of Italian Mothers.

    abstract::The extraordinary health emergency of the COVID-19 pandemic represents a new challenge for mental health researchers and clinical practitioners. The related containment measures may be a risk factor for psychological distress and mood disorders, especially in at-risk populations. This study aims to explore the impact ...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.589916

    authors: Spinola O,Liotti M,Speranza AM,Tambelli R

    更新日期:2020-11-17 00:00:00

  • Bibliometric and Visual Analysis of Research on the Links Between the Gut Microbiota and Depression From 1999 to 2019.

    abstract::Background: There is a crucial link between the gut microbiota and the host central nervous system, and the communication between them occurs via a bidirectional pathway termed the "microbiota-gut-brain axis." The gut microbiome in the modern environment has markedly changed in response to environmental factors. These...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.587670

    authors: Zhu X,Hu J,Deng S,Tan Y,Qiu C,Zhang M,Ni X,Lu H,Wang Z,Li L,Chen H,Huang S,Xiao T,Shang D,Wen Y

    更新日期:2021-01-08 00:00:00

  • Internet- and App-Based Stress Intervention for Distance-Learning Students With Depressive Symptoms: Protocol of a Randomized Controlled Trial.

    abstract::Background: Mental disorders are highly prevalent among university students. Distance-learning students are particularly burdened and have limited access to conventional university health services. Interventions for stress are sought after in distance learners and may help increase treatment coverage. Internet-based i...

    journal_title:Frontiers in psychiatry

    pub_type:

    doi:10.3389/fpsyt.2019.00361

    authors: Harrer M,Apolinário-Hagen J,Fritsche L,Drüge M,Krings L,Beck K,Salewski C,Zarski AC,Lehr D,Baumeister H,Ebert DD

    更新日期:2019-05-21 00:00:00

  • Pharmacological modulation of the short-lasting effects of antagonistic direct current-stimulation over the human motor cortex.

    abstract::Combined administration of transcranial direct current-stimulation (tDCS) with either pergolide (PER) or d-cycloserine (d-CYC) can prolong the excitability-diminishing effects of cathodal, or the excitability enhancing effect of anodal stimulation for up to 24 h poststimulation. However, it remains unclear whether the...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2012.00067

    authors: Chaieb L,Antal A,Terney D,Paulus W

    更新日期:2012-07-05 00:00:00

  • Comorbid Mental Disorders and 6-Month Symptomatic and Functioning Outcomes in Chinese University Students at Clinical High Risk for Psychosis.

    abstract:Background:High rates of non-psychotic psychopathological symptoms have been observed in clinical population at clinical high risk (CHR) for psychosis. These comorbid disorders affected the baseline functional level of CHR patients. However, little is known about the comorbid mental disorder in CHR individuals in non-c...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2017.00209

    authors: Shi J,Wang L,Yao Y,Su N,Zhan C,Mao Z,Zhao X

    更新日期:2017-10-23 00:00:00

  • Cinemotion, a Program of Cognitive Remediation to Improve the Recognition and Expression of Facial Emotions in Schizophrenia: A Pilot Study.

    abstract::Objective: Patients with schizophrenia exhibit impaired social cognition, especially in the recognition and expression of facial emotions, aspects of communication profoundly interlinked in an embodied approach of cognition. Nevertheless, many training programs have been developed that focus on either of these deficit...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2018.00312

    authors: Sevos J,Grosselin A,Gauthier M,Carmona F,Gay A,Massoubre C

    更新日期:2018-07-23 00:00:00

  • Using EEG-Guided Basket and Umbrella Trials in Psychiatry: A Precision Medicine Approach for Cognitive Impairment in Schizophrenia.

    abstract::Due to advances over the last several decades, many fields of medicine are moving toward a precision medicine approach where treatments are tailored to nuanced patient factors. While in some disciplines these innovations are commonplace leading to unique biomarker-guided experimental medicine trials, there are no such...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2018.00554

    authors: Joshi YB,Light GA

    更新日期:2018-11-19 00:00:00

  • Corrigendum: Preventing and Reducing Coercive Measures-An Evaluation of the Implementation of the Safewards Model in Two Locked Wards in Germany.

    abstract::[This corrects the article DOI: 10.3389/fpsyt.2019.00340.]. ...

    journal_title:Frontiers in psychiatry

    pub_type: 已发布勘误

    doi:10.3389/fpsyt.2020.00162

    authors: Baumgardt J,Jäckel D,Helber-Böhlen H,Stiehm N,Morgenstern K,Voigt A,Schöppe E,Mc Cutcheon AK,Velasquez Lecca EE,Löhr M,Schulz M,Bechdolf A,Weinmann S

    更新日期:2020-03-11 00:00:00

  • The use of very high-doses of baclofen for the treatment of alcohol-dependence: a case series.

    abstract::Baclofen, particularly high-dose baclofen, has recently emerged as a treatment of major interest for alcohol-dependence. However, baclofen has many potentially dangerous side effects, and the maximal dose of baclofen that may be used is a matter of discussion. Here, the author analyses the medical charts of the last 1...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2014.00143

    authors: de Beaurepaire R

    更新日期:2014-10-10 00:00:00

  • Mental Health Symptoms and Work-Related Stressors in Hospital Midwives and NICU Nurses: A Mixed Methods Study.

    abstract::Hospital midwives and neonatal intensive care (NICU) nurses frequently encounter work-related stressors and are therefore vulnerable to developing mental health problems, such as secondary traumatic stress, burnout, anxiety, and depression. However, so far, the exact nature of these work-related stressors (traumatic v...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2018.00364

    authors: Favrod C,Jan du Chêne L,Martin Soelch C,Garthus-Niegel S,Tolsa JF,Legault F,Briet V,Horsch A

    更新日期:2018-08-20 00:00:00

  • Employment, Studies and Feelings: Two to Nine Years After a Personalized Program of Cognitive Remediation in Psychiatric Patients.

    abstract::Employment rate in psychiatry is around 10 to 30%. Cognitive remediation (CR) associated with psychosocial rehabilitation shows good functional outcomes, with a high level of satisfaction in participants provided by tailored CR. However, few studies looked at the long-term outcome in participants who experienced such ...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00609

    authors: Amado I,Moualla M,Jouve J,Brénugat-Herné L,Attali D,Willard D,Rigaut B,Malangin B,Kern L,Meyniel C,Gaillard R,Plaze M,Perquier F,Yannick M

    更新日期:2020-07-03 00:00:00

  • Rethinking a Negative Event: The Affective Impact of Ruminative versus Imagery-Based Processing of Aversive Autobiographical Memories.

    abstract:INTRODUCTION:Ruminative (abstract verbal) processing during recall of aversive autobiographical memories may serve to dampen their short-term affective impact. Experimental studies indeed demonstrate that verbal processing of non-autobiographical material and positive autobiographical memories evokes weaker affective r...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2017.00082

    authors: Slofstra C,Eisma MC,Holmes EA,Bockting CLH,Nauta MH

    更新日期:2017-05-30 00:00:00

  • Development of the WHO Caregiver Skills Training Program for Developmental Disorders or Delays.

    abstract::Globally, 52.9 million children under the age of 5 experience a developmental disability, such as sensory impairment, intellectual disability, and autism spectrum disorders. Of these 95% live in low-and-middle-income countries. Most of these children lack access to care. In light of the growing evidence that caregiver...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2019.00769

    authors: Salomone E,Pacione L,Shire S,Brown FL,Reichow B,Servili C

    更新日期:2019-11-11 00:00:00

  • Computer-Assisted Cognitive-Behavioral Therapy to Treat Adolescents With Depression in Primary Health Care Centers in Santiago, Chile: A Randomized Controlled Trial.

    abstract::Introduction: Evidence from developed countries shows the efficacy of computer-assisted cognitive-behavioral therapy (cCBT) in addressing adolescent depression in home and/or school settings. This paper presents the results of a randomized controlled trial (RCT) of a brief therapist-guided cCBT intervention for adoles...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2019.00552

    authors: Martínez V,Rojas G,Martínez P,Gaete J,Zitko P,Vöhringer PA,Araya R

    更新日期:2019-07-30 00:00:00

  • Vagus Nerve Stimulation as a Treatment for Catatonia: A Hypothesis.

    abstract::Background: Catatonia is a syndrome comprising psychomotor, behavioral, and autonomous symptoms which may occur in the context of severe schizophrenic, affective, and other mental disorders or medical conditions. Treatment options include high dose benzodiazepines (lorazepam) and electroconvulsive therapy (ECT) with s...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2019.00086

    authors: Zilles D

    更新日期:2019-02-27 00:00:00

  • Sleep Quality as a Mediator in the Relationship Between Perceived Stress and Job Burnout Among Chinese Nurses: A Structural Equation Modeling Analysis.

    abstract::Background: Job burnout has become an increasing prevailing phenomenon among nurses in both developed and developing countries. There is a paucity of research exploring the relationship between perceived stress (i.e., the level of one's perception or appraisal of stress rather than objective stressful events) and job ...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.566196

    authors: Song Y,Yang F,Sznajder K,Yang X

    更新日期:2020-11-13 00:00:00

  • Suicidal Ideation in Newly-Diagnosed Chinese Cancer Patients.

    abstract:Objective:Suicide is one of the main reasons cited behind the death rate of cancer, and suicidal ideation (SI) is the first step toward it. This study aimed to investigate the prevalence and associates of suicidal ideation in newly-diagnosed Chinese cancer patients. Methods:This multicenter study was conducted from Ja...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00708

    authors: Zhang Y,Li W,Zhang Z,Sun H,Garg S,Yang Y,Wang H

    更新日期:2020-07-23 00:00:00

  • Decision-Making Dysfunctions of Counterfactuals in Depression: Who Might I have Been?

    abstract::Cognitive neuroscience enables us now to decompose major depressive disorder into dysfunctional component processes and relate these processes to specific neural substrates. This approach can be used to illuminate the biological basis of altered psychological processes in depression, including abnormal decision-making...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2013.00143

    authors: Howlett JR,Paulus MP

    更新日期:2013-11-08 00:00:00

  • Effects of Adolescent THC Exposure on the Prefrontal GABAergic System: Implications for Schizophrenia-Related Psychopathology.

    abstract::Marijuana is the most commonly used drug of abuse among adolescents. Considerable clinical evidence supports the hypothesis that adolescent neurodevelopmental exposure to high levels of the principal psychoactive component in marijuana, -delta-9-tetrahydrocanabinol (THC), is associated with a high risk of developing p...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2018.00281

    authors: Renard J,Rushlow WJ,Laviolette SR

    更新日期:2018-07-02 00:00:00

  • Long-Term Test-Retest Reliability of Auditory Gamma Oscillations Between Different Clinical EEG Systems.

    abstract:Objective:There is increasing interest in the utility of gamma-band activity for assessing various brain functions, including perception, language, memory, and cognition. The auditory steady-state response (ASSR) involves neural activity in the brain elicited by trains of a click sound, and its maximum response is obta...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00876

    authors: Hirano Y,Nakamura I,Tamura S,Onitsuka T

    更新日期:2020-09-02 00:00:00

  • Sex Differences in the Peripheral Immune System in Patients with Depression.

    abstract:BACKGROUND:Females are twice as likely as males to experience depression. Recent findings indicate a relationship linking inflammation with depression. Whether the higher prevalence of depression in women is sex-specific or if inflammation contributes to a higher prevalence of depression in females is unclear. Thus, th...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2017.00108

    authors: Birur B,Amrock EM,Shelton RC,Li L

    更新日期:2017-06-16 00:00:00

  • Astrocytic Regulation of Glutamate Transmission in Schizophrenia.

    abstract::According to the glutamate hypothesis of schizophrenia, the abnormality of glutamate transmission induced by hypofunction of NMDA receptors (NMDARs) is causally associated with the positive and negative symptoms of schizophrenia. However, the underlying mechanisms responsible for the changes in glutamate transmission ...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2018.00544

    authors: Mei YY,Wu DC,Zhou N

    更新日期:2018-11-06 00:00:00

  • Determinants of Mental Illness Among Humanitarian Migrants: Longitudinal Analysis of Findings From the First Three Waves of a Large Cohort Study.

    abstract::Background: As refugee numbers grow worldwide, understanding prevalence and determinants of mental illness in this population becomes increasingly important. Methods: We used longitudinal data to examine the initial years of resettlement in Australian refugees with a focus on ethnic-like social support. Three annual w...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2019.00545

    authors: Cooper S,Enticott JC,Shawyer F,Meadows G

    更新日期:2019-08-02 00:00:00